Prevalence of hepatitis B virus infection in out-patient alcoholics.

Abstract:

:Sera from 192 out-patient alcoholics attending a clinic for the treatment of alcoholism were tested for hepatitis B surface antigen (HBsAg) and for antibodies to HBsAg and to hepatitis B core antigen (HBcAg). Three sera (1.5%) were positive for HBsAg. Of the remaining 189 alcoholics, 29 (15%) were positive for one or both antibodies. This prevalence is not significantly different from that found in 137 hospitalized HBsAg-negative patients with alcoholic liver disease (35/137 [26%] were positive for one or both antibodies). However, the prevalence of hepatitis B antibodies in out-patient alcoholics is significantly (p less than 0.01) higher when compared with the prevalence in healthy volunteer blood donors (5/114 [4%] were positive for one or both antibodies). A comparison of out-patient alcoholics positive for one or both antibodies (n = 29) with patients negative for both antibodies (n = 160) revealed that the median age in the former group (46 years) was significantly (p less than 0.05) higher than that in the latter group (40 years).

journal_name

Infection

journal_title

Infection

authors

Gluud C,Gluud B,Aldershvile J,Jacobsen A,Dietrichson O

doi

10.1007/BF01641674

subject

Has Abstract

pub_date

1984-03-01 00:00:00

pages

72-4

issue

2

eissn

0300-8126

issn

1439-0973

journal_volume

12

pub_type

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