Abstract:
:Toxic shock syndrome (TSS) is a well-defined clinical syndrome attributed to certain exotoxins produced by Staphylococcus aureus. The acute episode is often characterized by a toxic encephalopathy, possibly caused by direct neurotoxicity of these exotoxins, although this mechanism has never been proven. We describe a patient who developed TSS, meningitis and cauda equina syndrome simultaneously several days after lumbar laminectomy. A space-occupying lesion was excluded. Enterotoxin C-producing S. aureus was cultured from the surgical wound and the cerebrospinal fluid (CSF). The patient recovered from TSS but remained partially paralyzed. Presumably the cauda equina syndrome was caused by neurotoxic effects of the intrathecally produced S. aureus exotoxins. This case provides evidence for the neurotoxic effects of TSS-associated S. aureus exotoxins.
journal_name
Infectionjournal_title
Infectionauthors
Arend SM,Steenmeyer AV,Mosmans PC,Bijlmer HA,van't Wout JWdoi
10.1007/BF01728901subject
Has Abstractpub_date
1993-07-01 00:00:00pages
248-50issue
4eissn
0300-8126issn
1439-0973journal_volume
21pub_type
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