Immunoglobulin class- and subclass-specific HIV antibody detection in serum and CSF specimens by ELISA and Western blot.

Abstract:

:Twenty-four homosexual adult patients suffering from LAS or AIDS were investigated for immunoglobulin class- and IgG subclass-specific antibodies to human immunodeficiency virus (HIV) by the indirect ELISA and Western blot using monoclonal tracer antibodies. All patients revealed HIV-specific serum antibodies of IgG subclass 1, and half of them IgG3. Only two had IgG2 and one IgG4 antibodies. IgM-anti-HIV was present in a person who presented a sero-conversion in subsequent blood specimens. In twelve patients who developed signs of an ongoing encephalitis, cerebrospinal fluid specimens were also tested. HIV-specific IgG antibodies were usually restricted to the subclass 1. In two cases specific IgM was found to be present, although lacking in the blood specimens. By comparison with HSV antibody detection in blood and CSF, an intrathecal, possibly pathognomonic antibody formation to HIV could be confirmed, mainly directed to gp120, gp41 and p24.

journal_name

Infection

journal_title

Infection

authors

Mergener K,Enzensberger W,Rübsamen-Waigmann H,von Briesen H,Doerr HW

doi

10.1007/BF01647729

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

317-22

issue

5

eissn

0300-8126

issn

1439-0973

journal_volume

15

pub_type

杂志文章
  • Operative management of intraabdominal infection.

    abstract::Surgical principles in the management of intraabdominal infection have remained constant. Rather, it is the application of these principles in selected cases that has varied. Judgement, therefore, becomes paramount for the surgeon. In selected cases multiple planned relaparotomies may be the most effective means of cl...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01726464

    authors: Aprahamian C,Wittmann DH

    更新日期:1991-11-01 00:00:00

  • Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases.

    abstract:INTRODUCTION:In the time of increasing resistance and paucity of new drug development there is a growing need for strategies to enhance rational use of antibiotics in German and Austrian hospitals. An evidence-based guideline on recommendations for implementation of antibiotic stewardship (ABS) programmes was developed...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-016-0885-z

    authors: de With K,Allerberger F,Amann S,Apfalter P,Brodt HR,Eckmanns T,Fellhauer M,Geiss HK,Janata O,Krause R,Lemmen S,Meyer E,Mittermayer H,Porsche U,Presterl E,Reuter S,Sinha B,Strauß R,Wechsler-Fördös A,Wenisch C,Kern

    更新日期:2016-06-01 00:00:00

  • [A microbiological method for the rapid determination of antibiotic concentrations during therapy].

    abstract::The assay described is an agar diffusion test using Bacillus stearothermophilus as test organism. Incubation is at 62° C; results can be obtained rapidly within 2 to 3 hours. The test was developed for the determination of gentamicin concentrations in serum and other body fluids. Because of its high sensitivity the te...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01642093

    authors: Wahlig H

    更新日期:1977-06-01 00:00:00

  • Neglected tropical diseases in Europe: rare diseases and orphan drugs?

    abstract::Neglected tropical diseases are becoming more and more frequent in Europe due to the increasing immigration from endemic areas. Nonetheless specific treatments are scarcely available in many European countries, since they are neither officially licensed nor marketed. Only a few referral health centres can afford to ac...

    journal_title:Infection

    pub_type: 社论

    doi:10.1007/s15010-018-1241-2

    authors: Calleri G,Angheben A,Albonico M

    更新日期:2019-02-01 00:00:00

  • [Altered bacterial periurethral flora in young girls with chronic, recurrent urinary tract infections? (author's transl)].

    abstract::Assuming a local weakness in the defence system to be responsible for chronic, recurrent infection of the urinary tract in young girls, we made 86 determinations of the bacterial periurethral flora from 70 female patients aged between five and eleven years. Within three patient groups (urologically healthy, temporaril...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01640729

    authors: Hofmann K,Marget W,Belohradsky B

    更新日期:1981-01-01 00:00:00

  • Onset of symptoms, diagnostic confirmation, and occurrence of multiple infective foci in patients with Staphylococcus aureus bloodstream infection: a look into the order of events and potential clinical implications.

    abstract:PURPOSE:Data on the systemic dissemination in Staphylococcus aureus bloodstream infection (SAB) remain sparse. We investigated the timing and the sequence of clinical symptoms, diagnostic confirmation, and occurrence of multiple infective foci in relation to three major infective foci. METHODS:From 2006 to 2011, all a...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-018-1165-x

    authors: Smit J,Rieg SR,Wendel AF,Kern WV,Seifert H,Schønheyder HC,Kaasch AJ

    更新日期:2018-10-01 00:00:00

  • A Thr72Ala polymorphism in the NKG2D gene is associated with early symptomatic congenital cytomegalovirus disease.

    abstract::The potential risk factors for congenital cytomegalovirus (cCMV) infection or development of disease remain unclear. Here, we investigated the genetic polymorphisms in natural killer (NK) group 2, member D (NKG2D), an activating receptor expressed on NK cells, and in MHC class I-related chains A, the ligand of NKG2D, ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-015-0774-x

    authors: Taniguchi R,Koyano S,Suzutani T,Goishi K,Ito Y,Morioka I,Nakamura H,Yamada H,Oka A,Inoue N

    更新日期:2015-06-01 00:00:00

  • Influence of intimal Chlamydophila pneumoniae persistence on cardiovascular complications after coronary intervention.

    abstract:PURPOSE:Chlamydophila pneumoniae has been implicated in atherosclerosis/restenosis; however, clear evidence is missing. Therefore, the aim of our study was to examine the influence of intimal infection and systemic inflammation on cardiovascular complications after coronary intervention. METHODS:45 atheroma specimens ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-014-0694-1

    authors: Tuleta I,Reek D,Braun P,Bauriedel G,Nickenig G,Skowasch D,Andrié R

    更新日期:2015-02-01 00:00:00

  • In-vitro activity of lomefloxacin (SC-47111) and other quinolones.

    abstract::The in vitro activity of lomefloxacin, a new difluorinated quinolone, was compared to that of ciprofloxacin, ofloxacin, norfloxacin and other relevant antibacterial agents. Lomefloxacin and norfloxacin shared similar activity, whereas ofloxacin and in particular ciprofloxacin showed superior activity. Most gram-negati...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644019

    authors: Sun ZM,Maskell JP,Sehgal SC,Williams JD

    更新日期:1989-05-01 00:00:00

  • Infectious keratitis and orthokeratology lens use: a systematic review.

    abstract:PURPOSE:Myopia is a prevalent condition among Asians. Orthokeratology lens has gained popularity as a method of myopia control. This systematic review is to summarize the clinical profile of infectious keratitis in association with orthokeratology lens wear. METHODS:We searched in the PubMed and EMBASE for articles ad...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-017-1023-2

    authors: Kam KW,Yung W,Li GKH,Chen LJ,Young AL

    更新日期:2017-12-01 00:00:00

  • The effects of ciprofloxacin on human chondrocytes in cell culture.

    abstract::Ciprofloxacin is a highly potent antibacterial agent that is used extensively in bone and joint infections. Because of reports of potential chondro-toxicity in animals, the effects of this drug on cells derived from human cartilage were tested in liquid micromass and agarose gel cultures. An inhibition of cell prolife...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01713325

    authors: Mont MA,Mathur SK,Frondoza CG,Hungerford DS

    更新日期:1996-03-01 00:00:00

  • The treatment of uncomplicated urinary tract infections with mezlocillin.

    abstract::Fourteen adult patients with uncomplicated urinary tract infections (UTI) caused by gram-negative and gram-positive bacteria were treated with 2 g mezlocillin daily by i. m. injection for an average of eight days. Clinical examinations were performed daily; bacteriological and laboratory controls (blood and urine) wer...

    journal_title:Infection

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF01640667

    authors: Coimbra F

    更新日期:1982-01-01 00:00:00

  • Release of vancomycin and teicoplanin from a plasticized and resorbable gelatin sponge: in vitro investigation of a new antibiotic delivery system with glycopeptides.

    abstract:BACKGROUND:The aim of this study was to evaluate the efficacy of sustained release of vancomycin and teicoplanin from a resorbable gelatin glycerol sponge, in order to establish a new delivery system for local anti-infective therapy. MATERIALS AND METHODS:60 plasticized glycerol gelatin sponges containing either 10 or...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-006-1067-1

    authors: Drognitz O,Thorn D,Krüger T,Gatermann SG,Iven H,Bruch HP,Muhl E

    更新日期:2006-02-01 00:00:00

  • Prenatal diagnosis of intrauterine rubella.

    abstract::The results of prenatal diagnosis of fetal rubella infection by specific IgM antibody detection in fetal infection by specific IgM antibody detection in fetal blood obtained in the 21st to 23rd weeks of pregnancy of women with different types of rubella problems during pregnancy (categorised in four groups) showed tha...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01646038

    authors: Enders G,Jonatha W

    更新日期:1987-05-01 00:00:00

  • [Experimental study of the local application of silver sulfadiazine, cefsulodin and povidone-iodine in burns].

    abstract::Non-infected standardized burns and those contaminated experimentally with a constant number of organisms of a selected Pseudomonas aeruginosa strain underwent varying forms of treatment with silver sulfadiazine, cefsulodin cream and povidone iodine ointment. Wound healing was controlled by evaluating the wound area. ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641022

    authors: Kaiser W,von der Lieth H,Potel J,Heymann H

    更新日期:1984-01-01 00:00:00

  • Six different strains of Neisseria meningitidis in a case with meningococcal sepsis and five contact persons in a boys' home.

    abstract:BACKGROUND:It is routine practice to provide chemoprophylaxis for close contacts of a patient infected with meningococci. PATIENTS:When a 17-year-old boy living in a boys' home was admitted to the hospital with septic shock caused by Neisseria meningitidis, we immediately identified contact persons in the boys' home. ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s150100050070

    authors: Linde H,Glück T,Metz M,Reng C,Erlmeier S,Lehn N

    更新日期:2000-05-01 00:00:00

  • Guidelines for medical research in children.

    abstract::Nearly everyone agrees that violations in research occur. Nobody knows how often. But if Pediatrics is to progress children must be the subjects of research carried out in an acceptable way. The following guidelines should be followed in childhood experimentation: (1) Research should not be done on children if the sam...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01645562

    authors: Papadatos CJ

    更新日期:1989-11-01 00:00:00

  • Fusobacterium nucleatum prosthetic hip infection in an adult with sickle cell-beta thalassemia.

    abstract::Fusobacterium nucleatum is an anaerobic Gram-negative bacillus commensal to the human oropharynx and gastrointestinal tract which causes an array of human infection, yet it has never been associated with infection of prosthetic joints. We report the first case of prosthetic hip infection caused by F. nucleatum in a ma...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0197-2

    authors: Verma K,McNabb PC,Kurtz W,Green J,Trabue CH

    更新日期:2012-06-01 00:00:00

  • Low rate of clinical consequences derived from results of blood cultures obtained in an internal medicine emergency department.

    abstract:BACKGROUND:Blood cultures detect bacteremia in individual patients and help define local pathogen and resistance spectra. At the same time, the benefits of blood culture results in the management of individual patients -- and therefore their cost-effectiveness -- are disputed. PATIENTS AND METHODS:During 1 calendar ye...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-005-5065-5

    authors: Ehrenstein BP,Jarry T,Linde HJ,Schölmerich J,Glück T

    更新日期:2005-10-01 00:00:00

  • Emergency endovascular stent-grafting for infected pseudoaneurysm of brachial artery.

    abstract::The use of covered stents in an infected field is controversial. It is generally recommended that infected aneurysms be treated using autografts or allografts. We report a case of infected brachial pseudoaneurysms that developed after medical debridement of a methicillin-resistant Staphylococcus aureus (MRSA)-infected...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-002-3046-5

    authors: Kurimoto Y,Tsuchida Y,Saito J,Yama N,Narimatsu E,Asai Y

    更新日期:2003-06-01 00:00:00

  • Meningitis in a girl with recurrent otitis media caused by Streptococcus pyogenes--otitis media has to be treated appropriately.

    abstract::Streptococcus pyogenes rarely causes meningitis. A recent increase in the incidence and severity of diseases due to S. pyogenes has been observed worldwide, without an apparent increase in the incidence of S. pyogenes meningitis. However, more recently severe and fulminant cases of S. pyogenes meningitis have been rep...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-001-1065-2

    authors: Steppberger K,Adams I,Deutscher J,Müller H,Kiess W

    更新日期:2001-10-01 00:00:00

  • Serum and sputum antibiotic levels after ampicillin, amoxycillin and bacampicillin chronic bronchitis patients.

    abstract::Serum and sputum concentrations of ampicillin or amoxycillin were measured in patients admitted to hospital for acute exacerbations of chronic bronchitis with purulent sputum. Mean peak serum levels of nearly 12 mg/l were found after 1600 mg bacampicillin (mean peak level in sputum 0.85 mg/l). The serum and sputum con...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01659773

    authors: Davies B,Maesen F

    更新日期:1979-01-01 00:00:00

  • Effectiveness of a multidimensional approach for prevention of ventilator-associated pneumonia in 11 adult intensive care units from 10 cities of Turkey: findings of the International Nosocomial Infection Control Consortium (INICC).

    abstract:PURPOSE:To evaluate the impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional approach on the reduction of ventilator-associated pneumonia (VAP) in adult patients hospitalized in 11 intensive care units (ICUs), from 10 hospitals, members of the INICC, in 10 cities of Turkey. METH...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s15010-013-0407-1

    authors: Leblebicioglu H,Yalcin AN,Rosenthal VD,Koksal I,Sirmatel F,Unal S,Turgut H,Ozdemir D,Ersoz G,Uzun C,Ulusoy S,Esen S,Ulger F,Dilek A,Yilmaz H,Turhan O,Gunay N,Gumus E,Dursun O,Yýlmaz G,Kaya S,Ulusoy H,Cengiz M

    更新日期:2013-04-01 00:00:00

  • Aortic thrombus and multiple embolisms during a Mycoplasma pneumoniae infection.

    abstract::We report the case of a patient who presented with a thrombus of the aortic arch complicated with splenic, renal and peroneal artery embolisms, associated with transient lupus anticoagulant, during a Mycoplasma pneumoniae infection. The outcome was good under antibiotic and anticoagulant treatment. We also review the ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-013-0475-2

    authors: Flateau C,Asfalou I,Deman AL,Ficko C,Andriamanantena D,Fontan E,Viant E,Bonnevie L,Rapp C

    更新日期:2013-08-01 00:00:00

  • Neuraminidase inhibitors in the treatment of influenza A and B--overview and case reports.

    abstract::Influenza viruses type A and B can cause a wide spectrum of illness, and they are responsible for considerable mortality and morbidity. With the new neuraminidase inhibitors, of which zanamivir was the first drug to be licensed, the physician has antivirals at his disposal which are safe and effective against both inf...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s150100070016

    authors: Wutzler P,Vogel G

    更新日期:2000-09-01 00:00:00

  • Efficacy of clarithromycin in preventing viridans streptococcal bacteremia following autologous stem cell transplantation.

    abstract:BACKGROUND:In a study involving 200 patients, we previously found that 17.5% of patients developed viridans streptococcal (VS) bacteremia following autologous peripheral blood stem cell transplantation (aPBSCT) when ciprofloxacin or ciprofloxacin plus ampicillin was used for prophylaxis. PATIENTS AND METHODS:A retrosp...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-001-1028-7

    authors: Naqvi B,Dorsky D,Ali SA,Feingold JM,Edwards RL,Bona RD,Clive J,Tutschka PJ,Bilgrami S

    更新日期:2001-08-01 00:00:00

  • Effect of pH on the in vitro activity of and propensity for emergence of resistance to fluoroquinolones, macrolides, and a ketolide.

    abstract::Antibiotic activity against common respiratory pathogens can be affected by the pH of the medium (in vitro) or the bodily fluid (in vivo) in which bacteria are present. The ionized fraction of an antibiotic is not able to efficiently penetrate bacterial or mammalian membranes, reducing the quantity of molecules able t...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-005-8206-y

    authors: Dalhoff A,Schubert S,Ullmann U

    更新日期:2005-12-01 00:00:00

  • Optimal duration of antimicrobial therapy for uncomplicated Gram-negative bloodstream infections.

    abstract:PURPOSE:Optimal antimicrobial treatment duration for Gram-negative bloodstream infection (BSI) remains unclear. This retrospective cohort study examined effectiveness of short (7-10 days) and long (>10 days) courses of antimicrobial therapy for uncomplicated Gram-negative BSI. METHODS:Hospitalized adults with uncompli...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-1020-5

    authors: Nelson AN,Justo JA,Bookstaver PB,Kohn J,Albrecht H,Al-Hasan MN

    更新日期:2017-10-01 00:00:00

  • Left and right ventricular dysfunction in patients with COVID-19-associated myocardial injury.

    abstract:PURPOSE:SARS-COV-2 infection can develop into a multi-organ disease. Although pathophysiological mechanisms of COVID-19-associated myocardial injury have been studied throughout the pandemic course in 2019, its morphological characterisation is still unclear. With this study, we aimed to characterise echocardiographic ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-020-01572-8

    authors: Bieber S,Kraechan A,Hellmuth JC,Muenchhoff M,Scherer C,Schroeder I,Irlbeck M,Kaeaeb S,Massberg S,Hausleiter J,Grabmaier U,Orban M,Weckbach LT

    更新日期:2021-01-30 00:00:00

  • Comparative trial of trimethoprim and co-trimoxazole in recurrent urinary infections.

    abstract::Eighty-nine patients with a history of recurrent urinary infection who required immediate treatment for significant bacteriuria were treated with either trimethoprim (300 mg at night) or with the standard course of co-trimoxazole (two tablets 12-hourly) for seven days. Cure rates one week after the end of treatment we...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01640874

    authors: Brumfitt W,Hamilton-Miller JM,Ludlam H,Damjanovic V,Gargan R

    更新日期:1982-09-01 00:00:00