Effect of pH on the in vitro activity of and propensity for emergence of resistance to fluoroquinolones, macrolides, and a ketolide.

abstract：:Preliminary data from the U.S. regarding the safety and efficacy of ofloxacin in the treatment of urinary tract infections are presented. Treatment of uncomplicated urinary tract infections with either 200 mg or 300 mg ofloxacin b.i.d. was as effective as treatment with a standard therapy, co-trimoxazole. In another s...

journal_title：Infection

authors： Cox CE,Callery SV,Tack KJ

更新日期：1986-01-01 00:00:00

abstract：:The original version of this article unfortunately contained a mistake. ...

journal_title：Infection

authors： Sagnelli C,Macera M,Pisaturo M,Zampino R,Coppola N,Sagnelli E

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:There are conflicting results concerning an association between Chlamydia pneumoniae and MS (multiple sclerosis). In the present study, we investigated a possible therapeutic option with antibiotics. PATIENTS AND METHODS:In our randomized, placebo-controlled double-blind study, 28 patients with the confirme...

journal_title：Infection

authors： Woessner R,Grauer MT,Frese A,Bethke F,Ginger T,Hans A,Treib J

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVES:There is increasing evidence indicating an association between invasive non-typeable Haemophilus influenzae (NTHi) infection in pregnancy and early pregnancy loss. As the diagnosis relies on microbiological investigation of post-mortem placental and foetal samples, a significant proportion of NTHi-related pr...

journal_title：Infection

authors： Cevik M,Moncayo-Nieto OL,Evans MJ

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Individuals with end-stage renal disease (ESRD) are 10- to 25-fold more likely than immunocompetent people to develop active tuberculosis (TB) and are candidates for being treated for latent TB infection (LTBI). However, diagnosis using the tuberculin skin test (TST) is doubly difficult due to cutaneous aner...

journal_title：Infection

authors： Lee SS,Chou KJ,Su IJ,Chen YS,Fang HC,Huang TS,Tsai HC,Wann SR,Lin HH,Liu YC

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:This study was undertaken to compare the clinical characteristics of adult methicillin-sensitive Staphylococcus aureus (MSSA) meningitis and adult methicillin-resistant S. aureus (MRSA) meningitis. PATIENTS AND METHODS:The clinical characteristics and therapeutic outcomes of 19 adult patients with S. aureus...

journal_title：Infection

authors： Chang WN,Lu CH,Wu JJ,Chang HW,Tsai YC,Chen FT,Chien CC

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Rotavirus is the major cause of gastroenteritis in children throughout the world. Every year, a large number of children aged < 5 years die from rotavirus-related diarrhoeal diseases. Though these infections are vaccine-preventable, the vast majority of children in low-income countries suffer from the infect...

journal_title：Infection

authors： Mahmud-Al-Rafat A,Muktadir A,Muktadir H,Karim M,Maheshwari A,Ahasan MM

更新日期：2018-02-01 00:00:00

abstract：:Toxic shock syndrome (TSS) is a well-defined clinical syndrome attributed to certain exotoxins produced by Staphylococcus aureus. The acute episode is often characterized by a toxic encephalopathy, possibly caused by direct neurotoxicity of these exotoxins, although this mechanism has never been proven. We describe a ...

journal_title：Infection

authors： Arend SM,Steenmeyer AV,Mosmans PC,Bijlmer HA,van't Wout JW

更新日期：1993-07-01 00:00:00

abstract：:The clinical tolrance of 350 mg pivampicillin tablets was evaluated in 470 hospitalized patients in Denmark, Norway and Iceland. The tablets were given to 229 fasting patients and to 241 non-fasting patients at mealtime. Side-effects were reported in 44 patients (9.4%). Upper gastro intestinal disturbances occurred in...

journal_title：Infection

authors： Hey H,Medalen TJ,Molstad OM,Stokholm K

更新日期：1977-01-01 00:00:00

abstract：PURPOSE:Since May 2016, WHO recommended a 9-12 month short-treatment regimen for multidrug-resistant tuberculosis (MDR-TB) treatment known as the 'Bangladesh Regimen'. However, limited data exist on the appropriateness thereof, and its implementation in low- and middle-income countries (LMIC). We report here on the pil...

journal_title：Infection

authors： Ateba-Ngoa U,Edoa JR,Adegbite BR,Rossatanga EG,Madiou D,Mfoumbi A,Mevyann C,Achimi Agbo P,Mahoumbou J,Gould S,Lell B,Adegnika AA,Köhler C,Kremsner PG,Massinga-Loembe M,Alabi A,Grobusch MP

更新日期：2019-10-01 00:00:00

abstract：:A microbiological analysis of 102 patients suffering from cystic fibrosis was conducted over a 22 month period. 20 microbial species with the following incidence were identified: Pseudomonas aeruginosa: 83.4%; Candida albicans: 29.4%; Staphylococcus aureus: 24.5%; Staphylococcus epidermidis: 11.8%; Haemophilus influen...

journal_title：Infection

authors： Bauernfeind A,Bertele RM,Harms K,Hörl G,Jungwirth R,Petermüller C,Przyklenk B,Weisslein-Pfister C

更新日期：1987-07-01 00:00:00

abstract：:Using bDNA, the plasma viral load trend of HCV-infected patients undergoing IFN therapy was analyzed. Nine patients were enrolled, each assigned to one of three groups, based on IFN response as determined by ALT and AST level trend. HCV was genotyped using DEIA. Each patient's clinical stage was determined by liver bi...

journal_title：Infection

authors： Iuliano R,Pizzigallo AM,Alecci A,Barsanti L,Trovato R,Forastieri G,Lico S,Palmieri C,Brizzi M,Marino N,Mecocci L,Mazzotta F,Ceccherini-Nelli L

更新日期：1996-07-01 00:00:00

abstract：PURPOSE:Infective endocarditis (IE) is a serious complication of bacteremia and is most often caused by Gram positive cocci. We investigated the prevalence of IE in patients where echocardiography was encouraged when bacteremia with Gram positive cocci was present. METHODS:The study included patients with Gram positiv...

journal_title：Infection

authors： Andersen MH,Holle SLK,Klein CF,Bruun NE,Arpi M,Bundgaard H,Tønder N,Iversen KK

更新日期：2020-12-01 00:00:00

abstract：:Here, we present a case of an immunocompetent 37-year old male who developed Aspergillus fumigatus osteomyelitis 16 years after extensive chest wall reconstructive surgery for Ewing sarcoma. His treatment course was complicated by a severe adverse drug reaction to voriconazole, requiring the use of oral posaconazole t...

journal_title：Infection

authors： Doub JB,Mathur P

更新日期：2020-12-01 00:00:00

abstract：:The pharmacokinetics and renal excretion of the sulphonamides sulphachloropyridazine, sulphadiazine, sulphaisodimidine, sulphamerazine, and sulphamethoxazole were investigated in a cross-over study with doses of 800 mg each. The serum half-life, urine levels, distribution volume, protein binding and potential antibact...

journal_title：Infection

authors： Ortengren B,Fellner H,Bergan T

更新日期：1979-01-01 00:00:00

abstract：:The radiologic surveillance of smokers with low-dose CT scan has led to a significant surge of radiologic incidental findings, including the detection of early stages of pulmonary infections including nontuberculous mycobacteria (NTM). This causes a state of overdiagnosis and potential overtreatment of NTM lung diseas...

journal_title：Infection

authors： Calzadilla A,Holt G,Campos M,Mirsaeidi M

更新日期：2018-12-01 00:00:00

abstract：:Ciprofloxacin (200 mg) was infused to seven patients at the beginning of elective colorectal surgery. Thirty minutes after the end of infusion (i.e. 60 min after the start of the operation) ciprofloxacin reached concentrations of 1.60 mg/l in serum and of 3.42-6.07 mg/kg fresh weight in the ileum and colon. During the...

journal_title：Infection

authors： Viell B,Krause B,Vestweber KH,Schaaf S,Scholl H

更新日期：1992-11-01 00:00:00

abstract：:In order to investigate the role played by zidovudine (ZDV) as immune modulator, particularly on B-cell response, the anti-V3 loop spectrotype in 115 sera from 26 HIV-infected individuals was evaluated, prior to and during treatment with ZDV, by isoelectric focusing and reverse blotting (IEF-RB), a technique useful fo...

journal_title：Infection

authors： Biselli R,Del Bono V,Anselmo M,Canessa A,Mazzarello G,D'Amelio R,Bassetti D

更新日期：1996-05-01 00:00:00

abstract：:Eighty-nine patients with a history of recurrent urinary infection who required immediate treatment for significant bacteriuria were treated with either trimethoprim (300 mg at night) or with the standard course of co-trimoxazole (two tablets 12-hourly) for seven days. Cure rates one week after the end of treatment we...

journal_title：Infection

authors： Brumfitt W,Hamilton-Miller JM,Ludlam H,Damjanovic V,Gargan R

更新日期：1982-09-01 00:00:00

abstract：:Using 44 anti-O sera 789 Escherichia coli strains isolated from the urine of patients with urinary tract infections were typed. Of the 119 E. coli strains from the urine of children, 49.6% were O-typable; only 3.4% were rough strains. Of 357 strains from pregnant women, 47% were O-typable; 12.1% were rough strains. Th...

journal_title：Infection

authors： Budde E,Naumann G,Nimmich W,Straube E

更新日期：1980-01-01 00:00:00

abstract：:The main objective was to develop a scoring system for easy use by the physician in daily clinical practice in deciding the appropriate treatment for his herpes zoster patient. Data from 635 patients who did not receive antiviral therapy were included in this analysis. Of these, 131 developed postherpetic neuralgia (P...

journal_title：Infection

authors： Meister W,Neiss A,Gross G,Doerr HW,Höbel W,Malin JP,von Essen J,Reimann BY,Witke C,Wutzler P

更新日期：1998-11-01 00:00:00

abstract：PURPOSE:Investigation of the injecting drug users (IDUs) population is becoming extremely critical and timely in light of the recent evidence that IDUs now act as the core of hepatitis C virus (HCV) epidemics in developed countries. The purpose of this article, therefore, is not only to review the epidemiology of HCV i...

journal_title：Infection

authors： Ramia S,Melhem NM,Kreidieh K

更新日期：2012-02-01 00:00:00

abstract：:Comparative functional and histological tests were performed in eight groups of ten quinea pigs each, which were administered 50, 75, 100 and 150 mg of netilmicin respecitvely b.i.d. for 29 days, 15 and 25 mg of gentamicin and 50 and 100 mg of amikacin per kg body weight respecitvely b.i.d. and in one control group of...

journal_title：Infection

authors： Federspil P

更新日期：1976-01-01 00:00:00

abstract：INTRODUCTION:Staphylococcus aureus frequently causes infections in outpatient and hospital settings and can present as a highly variable entity. Typical manifestations are endocarditis, osteoarticular infections or infection of implanted prostheses, intravascular devices or foreign bodies. A thorough diagnostic evaluat...

journal_title：Infection

authors： Koehler P,Jung N,Kochanek M,Lohneis P,Shimabukuro-Vornhagen A,Böll B

更新日期：2019-04-01 00:00:00

abstract：:A follow-up study of mother to infant transmission of hepatitis B virus was conducted in the Philippines between 1981 and 1983. The prevalence of HBsAg among 527 mothers was 8.5%. Overall, seven out of 17 (41.2%) infants born to HBsAg carrier mothers became HBsAg positive within the first 12 months of life. The risk o...

journal_title：Infection

authors： Lingao AL,Torres NT,Muñoz N,Lansang MA,West SK,Bosch FX,Domingo EO

更新日期：1989-09-01 00:00:00

abstract：:During the course of chronic hepatitis B virus (HBV) infection, a patient seropositive for hepatitis B e antigen experienced four episodes of acute hepatic necroinflammation. Serum HBV-DNA concentration elevated immediately before the first and third exacerbations, whereas serum hepatitis C virus (HCV) RNA was detecte...

journal_title：Infection

authors： Chen LW,Yeh CT,Fang KM,Chu CM,Liaw YF

更新日期：2001-12-01 00:00:00

abstract：:We analyzed the results of passive immunization against CMV in 146 heart transplant recipients. The 65 seronegative recipients were prophylactically treated with anti-CMV immunoglobulins during and after the operation. Twenty-nine of these 65 patients received a seropositive donor heart. CMV infection occurred in 21/6...

journal_title：Infection

authors： Balk AH,Weimar W,Rothbarth PH,Meeter K,Metselaar HJ,Mochtar B,Simoons ML

更新日期：1993-07-01 00:00:00

abstract：:Between 1 November 1993 and 31 October 1996, admissions to paediatric departments for Bordetella pertussis complications were reported to a nationwide, hospital-based active surveillance system. The case definition included pertussis complicated by pneumonia, apnoea requiring assisted ventilation, seizures, encephalop...

journal_title：Infection

authors： Herzig P,Hartmann C,Fischer D,Weil J,von Kries R,Giani G,Schroten H,Wirsing von König CH

更新日期：1998-07-01 00:00:00

abstract：:We present the case of an 11-month-old male infant who had been BCG vaccinated as a neonate. At the age of nine months, he developed a localized tumor above his right mamilla. The tumor destroyed the fourth rib and infiltrated the surrounding soft tissue. X-ray and CT scan suggested a malignant neoplasm. Histology, ho...

journal_title：Infection

authors： Hoppe JE,Orlikowsky T,Klingebiel T,Niethammer D

更新日期：1992-03-01 00:00:00

abstract：:The assay described is an agar diffusion test using Bacillus stearothermophilus as test organism. Incubation is at 62° C; results can be obtained rapidly within 2 to 3 hours. The test was developed for the determination of gentamicin concentrations in serum and other body fluids. Because of its high sensitivity the te...

journal_title：Infection

authors： Wahlig H

更新日期：1977-06-01 00:00:00