Abstract:
BACKGROUND:Rotavirus is the major cause of gastroenteritis in children throughout the world. Every year, a large number of children aged < 5 years die from rotavirus-related diarrhoeal diseases. Though these infections are vaccine-preventable, the vast majority of children in low-income countries suffer from the infection. The situation leads to severe economic loss and constitutes a major public health problem. METHODS:We searched electronic databases including PubMed and Google scholar using the following words: "features of rotavirus," "epidemiology of rotavirus," "rotavirus serotypes," "rotavirus in Bangladesh," "disease burden of rotavirus," "rotavirus vaccine," "low efficacy of rotavirus vaccine," "inactivated rotavirus vaccine". Publications until July 2017 have been considered for this work. RESULTS AND CONCLUSION:Currently, two live attenuated vaccines are available throughout the world. Many countries have included rotavirus vaccines in national immunization program to reduce the disease burden. However, due to low efficacy of the available vaccines, satisfactory outcome has not yet been achieved in developing countries such as Bangladesh. Poor economic, public health, treatment, and sanitation status of the low-income countries necessitate the need for the most effective rotavirus vaccines. Therefore, the present scenario demands the development of a highly effective rotavirus vaccine. In this regard, inactivated rotavirus vaccine concept holds much promise for reducing the current disease burden. Recent advancements in developing an inactivated rotavirus vaccine indicate a significant progress towards disease prophylaxis and control.
journal_name
Infectionjournal_title
Infectionauthors
Mahmud-Al-Rafat A,Muktadir A,Muktadir H,Karim M,Maheshwari A,Ahasan MMdoi
10.1007/s15010-017-1082-4subject
Has Abstractpub_date
2018-02-01 00:00:00pages
15-24issue
1eissn
0300-8126issn
1439-0973pii
10.1007/s15010-017-1082-4journal_volume
46pub_type
杂志文章,评审相关文献
INFECTION文献大全abstract::In a previous study we demonstrated that trimethoprim-sulfamethoxazole decreases the prevalence of infection in patients with severe granulocytopenia. However, treatment was accompanied by a relatively high incidence of multiresistant microorganisms. We therefore conducted this study to determine whether the addition ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01641298
更新日期:1983-05-01 00:00:00
abstract::Intestinal microsporidiosis with Enterocytozoon bieneusi was diagnosed in three of 18 HIV-infected patients with chronic diarrhoea. In two cases all known stages of the life cycle of E. bieneusi (merogonial plasmodia, sporogonial plasmodia, sporoblasts, spores) were found in duodenal biopsies by electron microscopical...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/BF01715501
更新日期:1994-11-01 00:00:00
abstract::Combinations of amoxicillin and clavulanic acid were tested against 11 Escherichia coli strains and five Klebsiella aerogenes strains. Apart from one E. coli, the strains were highly resistant to amoxicillin due to beta-lactamase production. Synergy was demonstrated in all strains by agar dilution. Synergy was detecte...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01641359
更新日期:1983-11-01 00:00:00
abstract::To assess the cost-effect relationship of aciclovir prophylaxis versus early treatment, we performed a retrospective study in 44 allogeneic bone marrow transplant recipients, who had only received aciclovir for therapeutic purposes. After bone marrow transplantation 18 herpes simplex infections occurred in 15 of the 3...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01643475
更新日期:1986-05-01 00:00:00
abstract::Turicella otitidis and Corynebacterium auris, described as new species 20 years ago, have been isolated mainly from the external ear canal and middle ear fluid. While their taxonomic position has been clearly established, their diagnosis in the routine laboratory is difficult. The question of their pathogenic potentia...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-013-0488-x
更新日期:2014-02-01 00:00:00
abstract::After the cytology and the chemistry of the CSF had returned to normal, the concentration of ceftizoxime was determined in the CSF and in the serum of 27 patients who had suffered from purulent or serous meningitis. The patients were divided into four groups. The concentration in the CSF was mean = 0.87 mg/l two hours...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01816728
更新日期:1982-01-01 00:00:00
abstract::A rare case of spontaneous spondylodiscitis caused by Klebsiella pneumoniae in a 55-year-old man who presented with thoracolumbar pain is described. Increased erythrocyte sedimentation rate and C-reactive protein level were pertinent laboratory findings. Computed tomography revealed a paravertebral mass and destructio...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s150100050046
更新日期:1999-11-01 00:00:00
abstract::A 53-year old immunocompetent Swiss female is described who developed severe meningoencephalitis due to infection with Cryptococcus gattii 13 months following exposure on Vancouver Island, Canada. Diagnosis was based on cerebrospinal fluid (CSF) examination, i.e., positive India-ink staining, positive latex particle a...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-008-8211-z
更新日期:2009-08-01 00:00:00
abstract::A 47-year-old man with newly diagnosed acute myeloblastic leukemia and non-insulin-dependent diabetes mellitus developed Trichosporon asahii fungemia while receiving caspofungin as empirical antifungal therapy. The diagnosis was based on repeated isolation of T. asahii in culture of blood for three times. Despite trea...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6278-6
更新日期:2008-02-01 00:00:00
abstract::The distribution of mannose-resistant (MRHA) and mannose-sensitive (MSHA) fimbrial haemagglutinins was examined in 482 strains of Escherichia coli isolated from 390 adult women and 45 pregnant mothers with a variety of urinary tract infections (UTI), and from 47 healthy controls. The proportion of MRHA strains was sig...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01641080
更新日期:1983-03-01 00:00:00
abstract:BACKGROUND:Microorganisms become attracted to polymer surfaces for a number of reasons including positive charge of biomaterial or concentration of nutrients on the biomaterial surface. Many bacteria additionally possess specific receptors for the interaction with extracellular host protein components that adhere on th...
journal_title:Infection
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s15010-002-3066-1
更新日期:2003-01-01 00:00:00
abstract::As perioperative prophylaxis for major orthopedic operations 81 patients were given the fixed combination of ampicillin (1 g)/sulbactam (0.5 g) or cefotiam (2 g) as short infusions. The three beta-lactams were rapidly distributed into the different tissues and their pharmacokinetic profiles were found to be very simil...
journal_title:Infection
pub_type: 临床试验,杂志文章
doi:10.1007/BF01713160
更新日期:1997-07-01 00:00:00
abstract::A 38-year-old Omani woman, seven months pregnant, developed extensive zygomycosis involving maxillary and temporal bones. No evidence of any underlying immune deficiency was detected except that which may be attributed to pregnancy. After delivery the patient was treated with repeated courses of amphotericin B, which ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF02033066
更新日期:1992-07-01 00:00:00
abstract::The epidemiological survey was carried out in a Calabrian population in order to ascertain the incidence of antibodies to Mycoplasma pneumoniae. In the past it has been felt that this infection does not occur in Southern Italy. We have found an incidence in our survey equal to that of the other countries. It was impos...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01638421
更新日期:1976-01-01 00:00:00
abstract::Thrombocytosis is rarely observed during infection. We are describing a patient with acute osteomyelitis and bacteremia who developed thrombocytosis. In the patient described the platelet count paralleled the activity of the infection and the response to therapy. The causes of thrombocytosis and its implications are b...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01645220
更新日期:1984-11-01 00:00:00
abstract::The minimum inhibitory concentrations (MIC) of ciprofloxacin were determined for 441 uropathogens from patients with complicated and/or hospital acquired urinary tract infections (UTI). None of the Enterobacteriaceae was resistant (MIC > or = 4 mg/l), but 21.7% of enterococci, 28.3% of Pseudomonas spp. and 38.5% of st...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01793576
更新日期:1994-01-01 00:00:00
abstract::In this open study the efficacy and tolerability of rufloxacin in a single dose of 400 mg the first day and 200 mg the nine consecutive days was studied in 26 patients with an acute exacerbation of chronic bronchitis. Twenty-two patients were evaluable for efficacy. Four patients stopped treatment prematurely after fi...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01644971
更新日期:1991-07-01 00:00:00
abstract::Pulmonary edema is a recognized complication of Plasmodium falciparum malaria but is uncommon with Plasmodium vivax infection. We report the case of a non-immune adult with imported P. vivax malaria who developed pulmonary edema during treatment. The case was further complicated by a recurrent malaria episode after fa...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6108-x
更新日期:2007-10-01 00:00:00
abstract::During the course of chronic hepatitis B virus (HBV) infection, a patient seropositive for hepatitis B e antigen experienced four episodes of acute hepatic necroinflammation. Serum HBV-DNA concentration elevated immediately before the first and third exacerbations, whereas serum hepatitis C virus (HCV) RNA was detecte...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-001-1195-6
更新日期:2001-12-01 00:00:00
abstract::The aim of the present open prospective study is to evaluate the efficacy and safety profile of fosfomycin trometamol in the chemoprophylaxis of urinary tract infections following transurethral diagnostic and/or therapeutic manoeuvres. 712 patients were enrolled in 72 urological surgical centres. All the enrolled pati...
journal_title:Infection
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/BF01643436
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:We examined lymphocyte apoptosis, activity of caspases-1, -3, -8 and -9 and the relationship between those two events and inflammation response in septic shock. MATERIALS AND METHODS:Blood samples were obtained within 24 h after diagnosis of septic shock from 16 patients to measure apoptosis, caspases-3, -8...
journal_title:Infection
pub_type: 信件
doi:10.1007/s15010-008-7070-y
更新日期:2008-10-01 00:00:00
abstract::Ten patients about to undergo a colorectal operation lasting an average of three hours received 500 mg each of imipenem and cilastatin i.v. preoperatively. During the operation blood and tissue samples were taken in order to determine the serum kinetics of the substances as well as the levels of imipenem in the cutis,...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01646409
更新日期:1990-11-01 00:00:00
abstract::The in vitro activity of the free acid of cefetamet pivoxil (Ro 15-8075) was tested against 355 clinical isolates, namely enteropathogenic bacteria, glucose non-fermentative gram-negative rods (excluding Pseudomonas aeruginosa) and Legionella pneumophila. Ceftriaxone was included in the study as reference compound. Al...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01644102
更新日期:1988-05-01 00:00:00
abstract::The penetration of ampicillin into middle ear effusions after oral administration of 800 mg bacampicillin to patients with acute otitis media was studied and compared with the serum levels. One hour after administration a mean (+/- SEM) concentration of 2.4 +/- 0.4 micrograms/ml ampicillin was found in the effusions a...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01659775
更新日期:1979-01-01 00:00:00
abstract::Association of renin-angiotensin system inhibitors with risk of death in patients with hypertension (HTN) and coronavirus disease 2019 (COVID-19) is not well characterized. The aim of this study was to evaluate the outcomes of patients with HTN and COVID-19 with respect to different chronic antihypertensive drug intak...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-020-01550-0
更新日期:2020-11-22 00:00:00
abstract::The in vitro activity of clarithromycin alone and in combination with its primary human metabolite, 14-hydroxy-clarithromycin, was determined against 203 strains of Haemophilus influenzae. Microdilution broth MICs and MBCs of both clarithromycin and 14-hydroxy-clarithromycin were determined. The clarithromycin MIC50 w...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01704612
更新日期:1992-05-01 00:00:00
abstract:PURPOSE:To assess incidence rate, risk factors and susceptibility patterns associated with extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli or Klebsiella pneumoniae in community-acquired urinary tract infections (CA-UTIs). METHODS:A prospective, case-control study was conducted at a tertiary teaching...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-018-1148-y
更新日期:2018-08-01 00:00:00
abstract::Whipple's disease is a rare systemic disorder classically presenting with weight loss, arthralgias, and diarrhea, which was first described in 1907. The causative bacterium Tropheryma whipplei, is a fastidious organism not growing on conventional media. Before the introduction of polymerase chain reaction (PCR)-based ...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-005-4067-7
更新日期:2005-02-01 00:00:00
abstract::313 anaerobic gram-negative rods of the Bacteroides genus isolated from 295 clinical specimens were tested for their sensitivity to azlocillin and mezlocillin using the dilution method with agar plates. 25 mg/l of azlocillin inhibited 80.2% of the strains and the same concentration of mezlocillin inhibited 86.9%. The ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01640681
更新日期:1982-01-01 00:00:00
abstract::After intravenous injection of single doses of 1.0 g of cefpirome (HR 810) and multiple doses of 1.0 g b.i.d. for five days to the same ten healthy male volunteers in an open design, concentrations of unchanged drug were estimated at various times in serum and urine, over 24 h and 48 h, respectively. Cefpirome concent...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01646053
更新日期:1987-05-01 00:00:00