Abstract：
PURPOSE:The purpose of this study was to evaluate the diagnostic value of 18F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT scan) and magnetic resonance imaging (MRI) in diagnosing spondylodiscitis and its complications, such as epidural and paraspinal abscesses. METHODS:From January 2006 to August 2013 patients with a clinical suspicion of spondylodiscitis, with an infection, or with fever of unknown origin were retrospectively included if 18F-FDG-PET/CT and MRI of the spine were performed within a 2-week time span. Imaging results were compared to the final clinical diagnosis and follow-up data were collected. RESULTS:Sixty-eight patients were included of whom 49 patients were diagnosed with spondylodiscitis. MRI showed an overall sensitivity of 67 % and specificity of 84 %. Diagnostic accuracy was 58 %, when MRI was performed within 2 weeks after the start of symptoms and improved to 82 %, when performed more than 2 weeks after onset of symptoms. 18F-FDG-PET/CT showed a sensitivity of 96 % and a specificity of 95 %, with no relation to the interval between the scan and the start of symptoms. CONCLUSIONS:As compared to MRI, 18F-FDG-PET/CT has superior diagnostic value for detecting early spondylodiscitis. After 2 weeks both techniques perform similarly.
journal_name
Infectionjournal_title
Infectionauthors
Smids C,Kouijzer IJ,Vos FJ,Sprong T,Hosman AJ,de Rooy JW,Aarntzen EH,de Geus-Oei LF,Oyen WJ,Bleeker-Rovers CPdoi
10.1007/s15010-016-0914-ysubject
Has Abstractpub_date
2017-02-01 00:00:00pages
41-49issue
1eissn
0300-8126issn
1439-0973pii
10.1007/s15010-016-0914-yjournal_volume
45pub_type
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