Abstract:
:Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are thrombotic microangiopathies increasingly reported in patients with HIV infection. However, characteristic features of thrombotic microangiopathies associated with HIV disease have not been defined yet. The typical courses of HUS and TTP in two patients are presented. The data as well as the analysis of cases published in the literature demonstrate the association of thrombotic microangiopathies with late-stage HIV disease. Moreover, differences between HUS and TTP can be detected. Patients with HUS present with more severe immunologic deterioration. Although clinical symptoms are fewer, HUS implicates a very poor prognosis. Life expectancy rarely exceeded 1 year after diagnosis. HUS and TTP should therefore be added to the international AIDS classification.
journal_name
Infectionjournal_title
Infectionauthors
Sutor GC,Schmidt RE,Albrecht Hdoi
10.1007/BF02565164keywords:
subject
Has Abstractpub_date
1999-01-01 00:00:00pages
12-5issue
1eissn
0300-8126issn
1439-0973journal_volume
27pub_type
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