Abstract:
OBJECTIVES:In endemic countries with a high level of chloroquine resistance, Plasmodium vivax malaria is associated with high morbidity and mortality. In these areas, the dihydroartemisinin-piperaquine combination resulted in clinical response, a more rapid clearance of parasitaemia, compared to chloroquine therapies, and reduction of recrudescence or reinfection. METHODS:We describe five cases of Plasmodium vivax malaria in returning travelers treated with dihydroartemisinin-piperaquine. RESULTS:All patients showed the early parasite clearance and no side effects. Our preliminary results suggest that the dihydroartemisinin-piperaquine combination is effective and safe even in imported cases. CONCLUSIONS:A unified treatment policy using the artemisinin combination therapy should be adopted even in non-endemic countries and larger studies are underway to support this strategy.
journal_name
Infectionjournal_title
Infectionauthors
Corpolongo A,Pisapia R,Oliva A,Giancola ML,Mencarini P,Bevilacqua N,Ghirga P,Mariano A,Vulcano A,Paglia MG,Nicastri Edoi
10.1007/s15010-019-01286-6subject
Has Abstractpub_date
2019-08-01 00:00:00pages
655-659issue
4eissn
0300-8126issn
1439-0973pii
10.1007/s15010-019-01286-6journal_volume
47pub_type
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