Abstract：
BACKGROUND:Based on previous studies, enterococcal infective endocarditis (IE) is considered a unimicrobial, community-acquired disease of older Caucasian men. PATIENTS AND METHODS:We evaluated the relationship between enterococcal bacteremia and IE by comparing clinical and demographic characteristics of all cases of enterococcal IE within an 8-year period (n = 41) with controls randomly chosen from patients with enterococcal bacteremia without IE. RESULTS:By univariate and multivariable analyses, the presence of a prosthetic valve (PV) and infection with Enterococcus faecalis were significantly associated with IE, while age, gender, race, polymicrobial infection and community-acquired infection were not. Almost an equal number of women and men had enterococcal IE. Cases of enterococcal IE were commonly nosocomial (39%) and polymicrobial (17%). CONCLUSIONS:Enterococcal endocarditis can no longer be considered exclusively a unimicrobial, community-acquired disease of Caucasian men. Instead, our data suggest that the presence of a PV and infection by E. faecalis are associated with an increased risk for IE.
journal_name
Infectionjournal_title
Infectionauthors
Anderson DJ,Murdoch DR,Sexton DJ,Reller LB,Stout JE,Cabell CH,Corey GRdoi
10.1007/s15010-004-2036-1keywords:
subject
Has Abstractpub_date
2004-04-01 00:00:00pages
72-7issue
2eissn
0300-8126issn
1439-0973journal_volume
32pub_type
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