[Effectiveness and tolerance of cefixime in bacterial infections in the ENT area].

Abstract:

:Clinical efficacy and tolerance of cefixime were investigated in an open, uncontrolled trial. 200 mg of cefixime were applied twice daily, duration of therapy was between eight and 14 days (mean value 10.1 days, standard deviation +/- 1.4 days). Ten male patients (mean age 42.7 years) and 19 female patients (mean age 34.4 years) were enrolled. Cure or improvement was observed in all 27 patients evaluable for efficacy of treatment. Bacteriological results based on 15 bacteriologically evaluable patients were: elimination of the initial pathogen 60%, persistence 40%. Unwanted side effects and their incidence among the 29 patients evaluable for tolerance were: diarrhoea eight patients (mild to moderate, limited to three to four days on average), nausea and vomiting one patient, discharge and pruritus one patient.

journal_name

Infection

journal_title

Infection

authors

Theopold M,Benner U,Bauernfeind A

doi

10.1007/BF01644629

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

S122-4

eissn

0300-8126

issn

1439-0973

journal_volume

18 Suppl 3

pub_type

临床试验,杂志文章
  • Assessment of immunomodulating activity of ofloxacin and three other quinolones in human plasma.

    abstract::A time-dependent degree of immunosuppression or immunostimulation which may be correlated to pharmacokinetic variables was obtained by administering a single dose of ofloxacin, norfloxacin, pipemidic and piromidic acid to healthy volunteers. The plasma samples collected before drug administration and then at various t...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01661284

    authors: De Simone C,Vullo V,Grassi M,Di Fabio S,Baldinelli L,Sorice F

    更新日期:1986-01-01 00:00:00

  • Immunoglobulin prophylaxis against hepatitis A among Swedish UN soldiers in an endemic region.

    abstract::Six hundred and fifteen Swedish soldiers (X = 24.9 years) serving with the UN forces in Cyprus were tested for antibody against hepatitis A (anti-HAV) before and after six months' service. Before the service, a high susceptibility to hepatitis A was found, as only 2.3% (14/615) had anti-HAV. In comparison, the prevale...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01648930

    authors: Weiland O,Berg JV,Bäck E,Lundbergh P

    更新日期:1979-01-01 00:00:00

  • New fluoroquinolones in lower respiratory tract infections and emerging patterns of pneumococcal resistance.

    abstract::The increasing resistance of Streptococcus pneumoniae, the most important community respiratory pathogen, to beta-lactams and other first-line antimicrobial agents usually employed for the empirical treatment of lower respiratory tract infections has led to the inclusion, in several current guidelines, of a fluoroquin...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-005-4102-8

    authors: Ferrara AM

    更新日期:2005-06-01 00:00:00

  • Infection in immunodepressed patients. The approach to diagnosis and treatment.

    abstract::Infection is an important cause of death in patients receiving cytostatic drugs or with any other impairment of host resistance. Such infections are frequently due to opportunist micro-organisms usually belonging to the endogenous flora of the patient. It is often difficult to obtain an exact diagnosis of the cause an...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01642766

    authors: Nauta EH,van Furth R

    更新日期:1975-01-01 00:00:00

  • IL-6 and TNF alpha release in association with neutrophil activation after cardiopulmonary bypass surgery.

    abstract::The serum IL-6 and TNF alpha response to cardiopulmonary bypass surgery was studied in 12 patients. Human neutrophil elastase was also measured in order to detect the presence of neutrophil activation. Peripheral venous blood samples were obtained before, during, and 1, 2, 3 and 6 days after surgery. Intra-operative s...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01780764

    authors: Holzheimer RG,Molloy RG,Görlach H,Wilkert S,Hehrlein F

    更新日期:1994-01-01 00:00:00

  • Coverage and predictors of adherence to influenza vaccination among Spanish children and adults with asthma.

    abstract:BACKGROUND:Influenza infections are frequently implicated in the exacerbation of asthma. The aim of this study was to assess vaccination coverage among Spanish children and adults with asthma and to describe the factors associated(predictors) with vaccination, using data from the 2006 Spanish National Health Survey. P...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-009-9069-4

    authors: Jiménez-García R,Hernández-Barrera V,Carrasco-Garrido P,de Andrés AL,de Miguel Diez J,de Miguel AG

    更新日期:2010-02-01 00:00:00

  • Femoral osteomyelitis due to Aspergillus nidulans in a patient with chronic granulomatous disease.

    abstract::13 cases of osteomyelitis caused by Aspergillus nidulans have been previously reported in patients with chronic granulomatous disease (CGD). All of them have been associated with simultaneous pulmonary infection and have had an extremely poor outcome. We report an unusual case of femoral osteomyelitis due to A. nidula...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-002-2167-1

    authors: Dotis J,Panagopoulou P,Filioti J,Winn R,Toptsis C,Panteliadis C,Roilides E

    更新日期:2003-03-01 00:00:00

  • Quantitative antibiotic use in hospitals: comparison of measurements, literature review, and recommendations for a standard of reporting.

    abstract:BACKGROUND:Reports on antibiotic use often lack complete definitions of the units of measurement, hampering the comparison of data between hospitals or hospital units. PATIENTS AND METHODS:To compare methods of measures of in-hospital antimicrobial use, we determined aggregate in-hospital consumption data at a tertiar...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-008-7462-z

    authors: Kuster SP,Ruef C,Ledergerber B,Hintermann A,Deplazes C,Neuber L,Weber R

    更新日期:2008-12-01 00:00:00

  • The potential impact of biomarker-guided triage decisions for patients with urinary tract infections.

    abstract:OBJECTIVES:Current guidelines provide limited evidence as to which patients with urinary tract infection (UTI) require hospitalisation. We evaluated the currently used triage routine and tested whether a set of criteria including biomarkers like proadrenomedullin (proADM) and urea have the potential to improve triage d...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-013-0423-1

    authors: Litke A,Bossart R,Regez K,Schild U,Guglielmetti M,Conca A,Schäfer P,Reutlinger B,Mueller B,Albrich WC

    更新日期:2013-08-01 00:00:00

  • Isolation of Chlamydia trachomatis from prostatic tissue of patients undergoing transurethral prostatectomy.

    abstract::Chlamydia trachomatis was isolated from three of 100 prostatic tissue specimens obtained from patients undergoing transurethral resection of the prostate. All examined patients were free from symptoms of urethral or prostatic inflammation. Our findings are in accordance with the high incidence of asymptomatic chlamydi...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01643241

    authors: Dan M,Samra Z,Siegel YI,Korczak D,Lindner A

    更新日期:1991-05-01 00:00:00

  • Thrombocytosis associated with acute osteomyelitis.

    abstract::Thrombocytosis is rarely observed during infection. We are describing a patient with acute osteomyelitis and bacteremia who developed thrombocytosis. In the patient described the platelet count paralleled the activity of the infection and the response to therapy. The causes of thrombocytosis and its implications are b...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01645220

    authors: Robey C,Chmel H

    更新日期:1984-11-01 00:00:00

  • Clinical significance of changes of flora in the upper digestive tract.

    abstract::Dysbiosis does not necessarily mean disease. Typical clinical picture of disease caused by metabolic activity of dysbiotic microflora is the microbial over-growth syndrome. We studied case histories of 434 patients without consideration of their basic illnesses and correlated them with types of dysbioses of duodenal j...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01639535

    authors: Knoke M,Bernhardt H

    更新日期:1989-07-01 00:00:00

  • Infections in the differential diagnosis of Bell's palsy: a plea for performing CSF analysis.

    abstract:PURPOSE:Peripheral facial nerve palsy (FP) is the most common single nerve affection. Most cases are idiopathic, but a relevant fraction is caused by potentially treatable aetiologies including infections. Not all current diagnosis and treatment guidelines recommend routine cerebrospinal fluid (CSF) analysis in the dia...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-016-0933-8

    authors: Henkel K,Lange P,Eiffert H,Nau R,Spreer A

    更新日期:2017-04-01 00:00:00

  • Analysis of the specific immune response against capsular polysaccharides of two patients with systemic enterococcal infections.

    abstract::Systemic enterococcal infections often lead to life-threatening disease. By analyzing the immune response of two patients with systemic enterococcal infections against enterococcal polysaccharide antigens, we found that both patients had antibodies against all four of the capsular serotypes identified to date. Antibod...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-005-5062-8

    authors: Hufnagel M,Huebner J

    更新日期:2005-10-01 00:00:00

  • Comparison of BacT/Alert blood culture bottles with lytic media for culture of peritoneal dialysis fluid.

    abstract::A comparison was made between the Septi-Chek "Release" system containing saponins, standard BacT/Alert blood culture bottles and FAN BacT/Alert blood culture bottles for culturing CAPD fluids. Seventy-seven CAPD effluent specimens were tested. No differences could be found. Therefore, lytic agents are not necessary wh...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01713570

    authors: Wüst J,von Graevenitz A

    更新日期:1995-11-01 00:00:00

  • In-vitro activity of lomefloxacin (SC-47111) and other quinolones.

    abstract::The in vitro activity of lomefloxacin, a new difluorinated quinolone, was compared to that of ciprofloxacin, ofloxacin, norfloxacin and other relevant antibacterial agents. Lomefloxacin and norfloxacin shared similar activity, whereas ofloxacin and in particular ciprofloxacin showed superior activity. Most gram-negati...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644019

    authors: Sun ZM,Maskell JP,Sehgal SC,Williams JD

    更新日期:1989-05-01 00:00:00

  • Serum and sputum antibiotic levels after ampicillin, amoxycillin and bacampicillin chronic bronchitis patients.

    abstract::Serum and sputum concentrations of ampicillin or amoxycillin were measured in patients admitted to hospital for acute exacerbations of chronic bronchitis with purulent sputum. Mean peak serum levels of nearly 12 mg/l were found after 1600 mg bacampicillin (mean peak level in sputum 0.85 mg/l). The serum and sputum con...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01659773

    authors: Davies B,Maesen F

    更新日期:1979-01-01 00:00:00

  • Pharmacokinetics of quinolone derivatives in the prostate.

    abstract::The pharmacokinetics of six quinolone derivatives were investigated in the human and dog prostate. The possible therapeutic applications of these findings are discussed. ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01643687

    authors: Madsen PO,Aagaard J

    更新日期:1991-01-01 00:00:00

  • Interaction between levothyroxine and indinavir in a patient with HIV infection.

    abstract::Drug interactions are an important and emerging problem in the treatment of HIV-infected patients. Protease inhibitors, like nonnucleoside reverse transcriptase inhibitors, are metabolized by the cytochrome P-450 enzyme system and each of these antiretroviral agents may interact with other drugs metabolized by this sy...

    journal_title:Infection

    pub_type: 信件

    doi:10.1007/s15010-002-2092-3

    authors: Lanzafame M,Trevenzoli M,Faggian F,Marcati P,Gatti F,Carolo G,Concia E

    更新日期:2002-01-01 00:00:00

  • [Microbiological diagnosis of septicemia].

    abstract::To detect microorganisms in the blood it is necessary not only that the microbiologist uses reliable methods, but also that the clinician takes a sufficient number of blood samples at the right point in time using a correct method for drawing the blood. The best results are obtained if the blood sample is transferred ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01639113

    authors: Rotter M

    更新日期:1977-03-01 00:00:00

  • Oxacillin-susceptible methicillin-resistant Staphylococcus aureus (OS-MRSA), a hidden resistant mechanism among clinically significant isolates in the Wessex region/UK.

    abstract:PURPOSE:Methicillin-resistant Staphylococcus aureus (MRSA) is defined as S. aureus genetically having the mecA or mecC genes or phenotypically showing minimum inhibitory concentration (MIC) of oxacillin higher than 2 mg/L. However, recently, cefoxitin/oxacillin-susceptible mecA-positive S. aureus (OS-MRSA) has been rep...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s15010-014-0641-1

    authors: Saeed K,Ahmad N,Dryden M,Cortes N,Marsh P,Sitjar A,Wyllie S,Bourne S,Hemming J,Jeppesen C,Green S

    更新日期:2014-10-01 00:00:00

  • Antimicrobial susceptibility of 1,422 Haemophilus influenzae isolates from respiratory tract infections in Spain. Results of a 1-year (1996-97) multicenter surveillance study. Spanish Surveillance Group for Respiratory Pathogens.

    abstract::A Haemophilus influenzae multicenter antimicrobial susceptibility surveillance was carried out. An overall beta-lactamase production rate of 25.7% was found, with significant differences between hospitals ranging between 7.9 and 47.9%. Presumable intrinsic resistance was found in 4.6% of strains. No differences in sus...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s150100050026

    authors: García-Rodríguez JA,Baquero F,García de Lomas J,Aguilar L

    更新日期:1999-01-01 00:00:00

  • Partial in vivo response to corticosteroid treatment in common variable immune deficiency.

    abstract::The case of a 13-year-old girl with CVI is presented who required steroid treatment for myositis. After three weeks of treatment, the serum IgM level increased about ten-fold. Specific antibodies to vaccination antigens, which despite adequate vaccination were absent prior to any kind of treatment, could be synthesize...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01643615

    authors: Wahn V,Grosse-Wilde H,Rosin H,Carls C,Göbel U

    更新日期:1985-01-01 00:00:00

  • Chlamydia trachomatis: serological diagnosis.

    abstract::Satisfactory methods for the serodiagnosis of Chlamydia trachomatis have been widely discussed in recent years. Until a decade ago, the complement-fixation test measuring group-specific antibody was the most widely applied technique. However, despite showing relatively high diagnostic sensitivity in systemic chlamydia...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01640711

    authors: Treharne JD

    更新日期:1982-01-01 00:00:00

  • Ceftizoxime (FK 749) in vitro antibacterial activity.

    abstract::The minimal inhibitory concentrations of ceftizoxime, cefotaxime, moxalactam, cefoperazone, cefotiam and cefamandole were determined against various species of gram-negative bacteria and against Staphylococcus aureus. Ceftizoxime was more active against Enterobacteriaceae than cefamandole, cefotiam and cefoperazone an...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641024

    authors: Husson MO,Courcol R,Izard D,Leclerc H

    更新日期:1984-01-01 00:00:00

  • Long-term seropositivity against Echinococcus multilocularis in an epidemiological follow-up study in southwestern Germany (Römerstein).

    abstract:BACKGROUND:Out of 2,560 participants in an epidemiological survey of alveolar echinococcosis (AE) performed in 1996 in southwestern Germany, 47 participants had tested seropositive in one of two crude antigen screening ELISAs and were inconspicuous on hepatic ultrasound. PATIENTS AND METHODS:Out of these 47 seroreacto...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-001-1153-3

    authors: Jensen B,Reuter S,Kratzer W,Naser K,Kächele V,Kimmig P,Kern P

    更新日期:2001-12-01 00:00:00

  • Evolution of antiretroviral prescription and response over a period of 8 years: an Italian multicentre observational prospective cohort study.

    abstract:BACKGROUND:There is very less information on the use of antiretroviral (ARV) drugs and viro-immunological outcome over calendar years in Italy. PATIENTS AND METHODS:We performed an analysis of a prospective observational cohort (MASTER) to assess antiretroviral drug use in first line HAART and explore whether initial ...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s15010-007-7227-0

    authors: Sighinolfi L,Torti C,Zeni C,Ghinelli F,Suter F,Maggiolo F,Antinori A,Antonucci G,Castelnuovo F,Ladisa N,Migliorino M,Novati S,De Luca A,Lo Caputo S,Paraninfo G,Tinelli C,Carosi G,Italian MASTER Database Cohort.

    更新日期:2008-06-01 00:00:00

  • The epidemiological burden and overall distribution of chronic comorbidities in coronavirus disease-2019 among 202,005 infected patients: evidence from a systematic review and meta-analysis.

    abstract:PURPOSE:The main purpose of this study was to examine the overall distribution of chronic comorbidities in coronavirus disease-19 (COVID-19) infected populations and the risk of the underlying burden of disease in terms of the case fatality ratio (CFR). METHODS:We carried out a systematic review and meta-analysis of s...

    journal_title:Infection

    pub_type: 杂志文章,meta分析

    doi:10.1007/s15010-020-01502-8

    authors: Mahumud RA,Kamara JK,Renzaho AMN

    更新日期:2020-12-01 00:00:00

  • Operative management of intraabdominal infection.

    abstract::Surgical principles in the management of intraabdominal infection have remained constant. Rather, it is the application of these principles in selected cases that has varied. Judgement, therefore, becomes paramount for the surgeon. In selected cases multiple planned relaparotomies may be the most effective means of cl...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01726464

    authors: Aprahamian C,Wittmann DH

    更新日期:1991-11-01 00:00:00

  • Combination therapy with an aminoglycoside for Staphylococcus aureus endocarditis and/or persistent bacteremia is associated with a decreased rate of recurrent bacteremia: a cohort study.

    abstract:PURPOSE:Although limited data exist on the efficacy and potential risk of synergistic aminoglycoside therapy for persistent Staphylococcus aureus bacteremia and endocarditis, aminoglycosides are frequently used in clinical practice. METHODS:As our study population, we included subjects fulfilling the modified Duke cri...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0189-2

    authors: Lemonovich TL,Haynes K,Lautenbach E,Amorosa VK

    更新日期:2011-12-01 00:00:00