Abstract:
:Drug interactions are an important and emerging problem in the treatment of HIV-infected patients. Protease inhibitors, like nonnucleoside reverse transcriptase inhibitors, are metabolized by the cytochrome P-450 enzyme system and each of these antiretroviral agents may interact with other drugs metabolized by this system. Some protease inhibitors may also interact with glucuronosyl transferase activity affecting plasma concentrations of drugs metabolized through this pathway. We describe a case of an HIV-infected patient, taking levothyroxine for hypothyroidism and clinically stable, who, after the introduction of an antiretroviral regimen containing indinavir, developed a pharmacological hyperthyroidism.
journal_name
Infectionjournal_title
Infectionauthors
Lanzafame M,Trevenzoli M,Faggian F,Marcati P,Gatti F,Carolo G,Concia Edoi
10.1007/s15010-002-2092-3keywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
54-5issue
1eissn
0300-8126issn
1439-0973journal_volume
30pub_type
信件相关文献
INFECTION文献大全abstract:PURPOSE:To describe the influence of cardiac conduction tissue infection by Influenza A virus. METHODS AND RESULTS:A 54-year-old man with non-sustained ventricular tachycardia underwent noninvasive and invasive cardiac studies including left ventricular endomyocardial biopsy (LVEMB). Non-invasive studies showed normal...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-016-0892-0
更新日期:2016-06-01 00:00:00
abstract::Preliminary data from the U.S. regarding the safety and efficacy of ofloxacin in the treatment of urinary tract infections are presented. Treatment of uncomplicated urinary tract infections with either 200 mg or 300 mg ofloxacin b.i.d. was as effective as treatment with a standard therapy, co-trimoxazole. In another s...
journal_title:Infection
pub_type: 临床试验,杂志文章
doi:10.1007/BF01661300
更新日期:1986-01-01 00:00:00
abstract::Alternatives to conventional hospitalization are needed to increase health systems resilience in the face of COVID-19 pandemic. Herein, we describe the characteristics and outcomes of 63 patients admitted to a single HaH during the peak of COVID-19 in Barcelona. Our results suggest that HaH seems to be a safe and effi...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-020-01527-z
更新日期:2020-09-29 00:00:00
abstract::Fusobacterium nucleatum is an anaerobic Gram-negative bacillus commensal to the human oropharynx and gastrointestinal tract which causes an array of human infection, yet it has never been associated with infection of prosthetic joints. We report the first case of prosthetic hip infection caused by F. nucleatum in a ma...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-011-0197-2
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:SARS-COV-2 infection can develop into a multi-organ disease. Although pathophysiological mechanisms of COVID-19-associated myocardial injury have been studied throughout the pandemic course in 2019, its morphological characterisation is still unclear. With this study, we aimed to characterise echocardiographic ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-020-01572-8
更新日期:2021-01-30 00:00:00
abstract::The antibiotic most appropriate for prophylaxis of postoperative infections depends on the nature of the operation. In aseptic (clean) operations, gram-positive postoperative infections are the primary concern, and cefazolin is recommended because of its excellent pharmacokinetics and good activity against gram-positi...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/BF01715775
更新日期:1991-01-01 00:00:00
abstract::A guinea pig model of experimental Pseudomonas aeruginosa pneumonia was used to evaluate factors affecting the efficacy of passive immune therapy with Psomaglobin N, a hyperimmune P. aeruginosa globulin. Animals treated 2 h after infection with a single intravenous infusion of Psomaglobin N, 500 mg/kg, demonstrated 33...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01644192
更新日期:1987-01-01 00:00:00
abstract::313 anaerobic gram-negative rods of the Bacteroides genus isolated from 295 clinical specimens were tested for their sensitivity to azlocillin and mezlocillin using the dilution method with agar plates. 25 mg/l of azlocillin inhibited 80.2% of the strains and the same concentration of mezlocillin inhibited 86.9%. The ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01640681
更新日期:1982-01-01 00:00:00
abstract::The penetration of ampicillin into middle ear effusions after oral administration of 800 mg bacampicillin to patients with acute otitis media was studied and compared with the serum levels. One hour after administration a mean (+/- SEM) concentration of 2.4 +/- 0.4 micrograms/ml ampicillin was found in the effusions a...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01659775
更新日期:1979-01-01 00:00:00
abstract::The first case of Actinobacillus actinomycetem-comitans endocarditis in a child with a prosthetic cardiac valve is reported. Endocarditis was possibly caused by dental work done without antibiotic prophylaxis four weeks prior to admission. ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01645955
更新日期:1984-07-01 00:00:00
abstract:INTRODUCTION:After the introduction of highly active antiretroviral treatment, the course of HIV infection turned into a chronic disease and most of HIV-positive patients will soon be over 50 years old. MATERIAL AND METHODS:This paper reviews the multiple aspects that physicians have to face while taking care of HIV-p...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-015-0795-5
更新日期:2015-10-01 00:00:00
abstract::Six hundred and fifteen Swedish soldiers (X = 24.9 years) serving with the UN forces in Cyprus were tested for antibody against hepatitis A (anti-HAV) before and after six months' service. Before the service, a high susceptibility to hepatitis A was found, as only 2.3% (14/615) had anti-HAV. In comparison, the prevale...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01648930
更新日期:1979-01-01 00:00:00
abstract::A case of appendicitis followed by reactive arthritis in an HLA B27-positive, 29-year-old man after infection with Yersinia enterocolitica is reported. Infection with Y. enterocolitica was diagnosed by determination of serotype specific antibodies and antibodies to Yersinia outer membrane proteins. Bacteriological cul...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01720409
更新日期:1997-09-01 00:00:00
abstract::The results of prenatal diagnosis of fetal rubella infection by specific IgM antibody detection in fetal infection by specific IgM antibody detection in fetal blood obtained in the 21st to 23rd weeks of pregnancy of women with different types of rubella problems during pregnancy (categorised in four groups) showed tha...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01646038
更新日期:1987-05-01 00:00:00
abstract::In a randomized study, 42 patients undergoing extensive maxillo-facial surgery (correction of the position of the mandible or maxilla by using autologous bone transplants) received prophylactically ten-day courses of either flucloxacillin or amoxicillin with clavulanic acid. Patients were comparable with regard to age...
journal_title:Infection
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01644122
更新日期:1987-07-01 00:00:00
abstract::124 consecutive patients (mean age: 41.1 years; range: 20-63 years) attending an outpatient alcoholic clinic were tested for the presence of markers of HBV infection. HBsAg was found in 26 (21%), anti-HBs and/or anti-HBc in the absence of HBsAg in 35 (28%). Altogether, at least one marker was present in 61 (49%), thes...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01644546
更新日期:1988-01-01 00:00:00
abstract::In a comparative, prospective, open randomised clinical study, the efficacy and tolerance of cefaclor (3 x 500 mg) and amoxicillin (3 x 750 mg) in the treatment of urinary tract infection (UTI) were investigated and compared. A total of 110 patients (51 males and 59 females) age 10 to 83 years were treated for a perio...
journal_title:Infection
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01659750
更新日期:1979-01-01 00:00:00
abstract:BACKGROUND:A retrospective study was conducted to provide epidemiological data on hospitalization for complicated and uncomplicated chickenpox in a pediatric population. METHODS:The study analyzed hospitalization cases for chickenpox, among all the 31 Tuscan hospitals, during the period 1997-2003. RESULTS:Globally, 6...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6248-z
更新日期:2007-12-01 00:00:00
abstract::The prevalence of anti-HCV antibodies and the risk factors for HCV infection were assessed in 5,672 pregnant women living in North Italy. All reactive sera were confirmed by RIBA-2 test. Anti-HCV positive pregnant women together with an anti-HCV negative control group, were interviewed by standardised questionnaire to...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01715541
更新日期:1994-09-01 00:00:00
abstract::Pneumopericardium, the presence of air in the pericardial space, is a rare disorder that is usually caused by trauma. We describe a patient given induction chemotherapy for acute myelogenous leukemia who developed pulmonary aspergillosis that resulted in pericarditis and pneumopericardium. He responded to antifungal t...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/BF01739015
更新日期:1994-03-01 00:00:00
abstract::The aim of the present open prospective study is to evaluate the efficacy and safety profile of fosfomycin trometamol in the chemoprophylaxis of urinary tract infections following transurethral diagnostic and/or therapeutic manoeuvres. 712 patients were enrolled in 72 urological surgical centres. All the enrolled pati...
journal_title:Infection
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/BF01643436
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:To develop recommendations for the management of acute hepatitis B by the Italian Society for the Study of Infectious and Tropical Diseases. METHODS:Development of the recommendations divided into three levels of evidence according to the GRADE system: A (high), B (medium) and C (low experts opinion), together...
journal_title:Infection
pub_type: 杂志文章,实务指引,评审
doi:10.1007/s15010-014-0642-0
更新日期:2014-10-01 00:00:00
abstract::A simple, sensitive and rapid ELISA method for the quantification and characterization of antibodies to lipid A has been developed, which can also be applied to other hydrophobic antigens. For coating, antigens were applied to the wells of ELISA plates as solutions in a mixture of chloroform and ethanol 1:9 (v/v), and...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01650719
更新日期:1989-09-01 00:00:00
abstract::The epidemiological survey was carried out in a Calabrian population in order to ascertain the incidence of antibodies to Mycoplasma pneumoniae. In the past it has been felt that this infection does not occur in Southern Italy. We have found an incidence in our survey equal to that of the other countries. It was impos...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01638421
更新日期:1976-01-01 00:00:00
abstract:PURPOSE:Although limited data exist on the efficacy and potential risk of synergistic aminoglycoside therapy for persistent Staphylococcus aureus bacteremia and endocarditis, aminoglycosides are frequently used in clinical practice. METHODS:As our study population, we included subjects fulfilling the modified Duke cri...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-011-0189-2
更新日期:2011-12-01 00:00:00
abstract::A microbiological analysis of 102 patients suffering from cystic fibrosis was conducted over a 22 month period. 20 microbial species with the following incidence were identified: Pseudomonas aeruginosa: 83.4%; Candida albicans: 29.4%; Staphylococcus aureus: 24.5%; Staphylococcus epidermidis: 11.8%; Haemophilus influen...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/BF01644137
更新日期:1987-07-01 00:00:00
abstract::Iatrogenic meningitis following lumbar puncture is a rare complication of myelography, spinal anesthesia, intrathecal chemotherapy, and epidural anesthesia. Sporadic cases and clusters of iatrogenic meningitis have been reported after intrathecal therapy, but most incidental cases are reported after myelography. Four ...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/BF01780647
更新日期:1996-01-01 00:00:00
abstract::The most efficient route of transmission of hepatitis C virus (HCV) infection is through contaminated blood. Sexual transmission or other close human contact could play a role in sporadic infections. We describe a case of acute hepatitis C progressing to chronic hepatitis over a follow-up of 4 years in a 44-year-old w...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-007-6188-7
更新日期:2007-12-01 00:00:00
abstract::Bacterial meningitis of infants and children exact a major toll worldwide. Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis continue to be the major causes, and efforts to reduce the incidence of this disease have had limited success. Major advances in rapid diagnosis, such as antigen detect...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/BF01641744
更新日期:1984-01-01 00:00:00
abstract:PURPOSE:Invasive Mycobacterium marinum disease (tenosynovitis and osteomyelitis) may be an increasingly common manifestation of M. marinum infection that presents unique diagnostic and therapeutic challenges. We conducted a retrospective case series and literature review of M. marinum infection to better understand the...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-015-0776-8
更新日期:2015-12-01 00:00:00