[A microbiological method for the rapid determination of antibiotic concentrations during therapy (author's transl)].

Abstract:

:The assay described is an agar diffusion test using Bacillus stearothermophilus as test organism. Incubation is at 62 degrees C; results can be obtained rapidly within 2 to 3 hours. The test was developed for the determination of gentamicin concentrations in serum and other body fluids. Because of its high sensitivity the test strain is also suitable for the determination of other antibiotics. The test is designed primarily for the determination of concentrations in individual samples and thus for monitoring during therapy. The ease with which the test can be carried out is thus an important feature of it. On comparison with a standard method (agar diffusion test) using both serum samples from patients and samples with known gentamicin concentrations a highly significant correlation (r = 0.95) was seen between the two methods.

journal_name

Infection

journal_title

Infection

authors

Wahlig H

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

117-8

issue

2

eissn

0300-8126

issn

1439-0973

journal_volume

5

pub_type

杂志文章
  • A before-after study of multi-resistance and cost of selective decontamination of the digestive tract.

    abstract:BACKGROUND:We compared standard antibiotic use with an antibiotic policy based on selective decontamination of the digestive tract (SDD) for cost and microbiology. PATIENTS AND METHODS:A 2-year before-after observational study was performed in an 11-bed, mixed medical and surgical intensive care unit (ICU). We include...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-004-3170-5

    authors: van der Voort PH,van Roon EN,Kampinga GA,Boerma EC,Gerritsen RT,Egbers PH,Kuiper MA

    更新日期:2004-10-01 00:00:00

  • Aortic thrombus and multiple embolisms during a Mycoplasma pneumoniae infection.

    abstract::We report the case of a patient who presented with a thrombus of the aortic arch complicated with splenic, renal and peroneal artery embolisms, associated with transient lupus anticoagulant, during a Mycoplasma pneumoniae infection. The outcome was good under antibiotic and anticoagulant treatment. We also review the ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-013-0475-2

    authors: Flateau C,Asfalou I,Deman AL,Ficko C,Andriamanantena D,Fontan E,Viant E,Bonnevie L,Rapp C

    更新日期:2013-08-01 00:00:00

  • Home and hospital antibiotic treatment prove similarly effective in cystic fibrosis.

    abstract:BACKGROUND:Home intravenous antibiotic treatment has added to therapeutic options against Pseudomonas aeruginosa in cystic fibrosis (CF) patients leading to increased flexibility. A prospective clinical study was carried out to compare home and hospital iv antibiotic treatment in CF patients with chronic P. aeruginosa ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-002-2095-0

    authors: Riethmueller J,Busch A,Damm V,Ziebach R,Stern M

    更新日期:2002-12-01 00:00:00

  • Procalcitonin and C-reactive protein levels in community-acquired pneumonia: correlation with etiology and prognosis.

    abstract:BACKGROUND:The diagnostic value of admission serum levels of procalcitonin (PCT) and C-reactive protein (CRP) as indicators of the etiology and prognosis was prospectively investigated. PATIENTS:96 patients, 50-85 years of age, treated in the hospital for community-acquired pneumonia (CAP). RESULTS:On admission, all ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s150100050049

    authors: Hedlund J,Hansson LO

    更新日期:2000-03-01 00:00:00

  • Kinetics and correlation with body temperature of circulating interleukin-6, interleukin-8, tumor necrosis factor alpha and interleukin-1 beta in patients with fever and neutropenia.

    abstract::Interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), interleukin-8 (IL-8) and tumor necrosis factor alpha (TNF) are important mediators of fever and inflammation, and are involved in the pathogenesis of sepsis. There is only limited data on serum concentrations of these proinflammatory cytokines in patients with feve...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01716695

    authors: Engel A,Kern WV,Mürdter G,Kern P

    更新日期:1994-05-01 00:00:00

  • Specific anti cross-infection measures may help to prevent viral contamination of dental unit waterlines: a pilot study.

    abstract:BACKGROUND:In recent years, several reports have suggested, but never definitely demonstrated that dental units (DU) could be potential sources of viral cross-infections sustained by viral agents including HBV, HCV and HIV. This work aims at assessing the risk of HCV cross-infection by dental unit water lines (DUWLs). ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-008-7246-5

    authors: Artini M,Scoarughi GL,Papa R,Dolci G,De Luca M,Orsini G,Pappalardo S,Costerton JW,Selan L

    更新日期:2008-10-01 00:00:00

  • First report of chronic implant-related septic arthritis and osteomyelitis due to Kytococcus schroeteri and a review of human K. schroeteri infections.

    abstract::We report the first case of Kytococcus schroeteri implant-related septic arthritis and osteomyelitis, identified by phenotypic tests and 16S rRNA sequencing, which responded to implant removal and doxycycline. 16S rRNA sequencing was useful for the accurate and rapid identification of the organism as it exhibited thre...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-012-0250-9

    authors: Chan JF,Wong SS,Leung SS,Fan RY,Ngan AH,To KK,Lau SK,Yuen KY,Woo PC

    更新日期:2012-10-01 00:00:00

  • Resignment: Infection is grateful to Prof. Alexander von Graevenitz.

    abstract:: ...

    journal_title:Infection

    pub_type: 社论

    doi:10.1007/s15010-018-1228-z

    authors: Bogner JR

    更新日期:2018-12-01 00:00:00

  • Treatment of recurrent Clostridium difficile infection: a systematic review.

    abstract:BACKGROUND:Clostridium difficile infection (CDI) recurs in nearly one-third of patients who develop an initial infection. Recurrent CDI (RCDI) is associated with considerable morbidity, mortality, and cost. Treatment for RCDI has not been not well examined. METHODS:A systematic review. RESULTS:Sixty-four articles wer...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-013-0496-x

    authors: O'Horo JC,Jindai K,Kunzer B,Safdar N

    更新日期:2014-02-01 00:00:00

  • Evaluation of S. aureus ID, a chromogenic agar medium for the detection of Staphylococcus aureus.

    abstract:BACKGROUND:Screening for staphylococci among various patient populations has become important for appropriate therapeutic management and for control of nosocomial infections. The purpose of this study is to evaluate the in vitro sensitivity and specificity of a chromogenic agar medium, S. aureus ID (bioMérieux, France)...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-006-5094-8

    authors: Diederen BM,van Leest CM,van Duijn I,Willemse P,van Keulen PH,Kluytmans JA

    更新日期:2006-04-01 00:00:00

  • Low C-reactive protein values at admission predict mortality in patients with severe community-acquired pneumonia caused by Streptococcus pneumoniae that require intensive care management.

    abstract:PURPOSE:To identify risk factors associated with mortality in patients with severe community-acquired pneumonia (CAP) caused by S. pneumoniae who require intensive care unit (ICU) management, and to assess the prognostic values of these risk factors at the time of admission. METHODS:Retrospective analysis of all conse...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-015-0755-0

    authors: Que YA,Virgini V,Lozeron ED,Paratte G,Prod'hom G,Revelly JP,Pagani JL,Charbonney E,Eggimann P

    更新日期:2015-04-01 00:00:00

  • In-vitro activity of lomefloxacin (SC-47111) and other quinolones.

    abstract::The in vitro activity of lomefloxacin, a new difluorinated quinolone, was compared to that of ciprofloxacin, ofloxacin, norfloxacin and other relevant antibacterial agents. Lomefloxacin and norfloxacin shared similar activity, whereas ofloxacin and in particular ciprofloxacin showed superior activity. Most gram-negati...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01644019

    authors: Sun ZM,Maskell JP,Sehgal SC,Williams JD

    更新日期:1989-05-01 00:00:00

  • HAART-prolonged life of HIV-infected patients should not be shortened by hepatitis C.

    abstract::As highly active antiretroviral treatment (HAART) prolongs the life of HIV-infected individuals and reduces mortality associated with opportunistic infections, liver diseases have become a major challenge in the management of these patients. up to 45% of deaths of persons with HIV are related to endstage liver disease...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-004-6604-1

    authors: Horster S,Goebel FD

    更新日期:2004-12-01 00:00:00

  • Protective effect of an outer membrane vaccine against Pseudomonas aeruginosa infection.

    abstract::The outer membrane proteins, F, H2 and I, from PA12 strain of Pseudomonas aeruginosa, were purified and used successfully for immunization of Balb/c mice. The immunized mice were protected against challenge with a 2-26 fold LD50 of all known 19 serogroups of P. aeruginosa. ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01647755

    authors: von Specht BU,Strigl G,Ehret W,Brendel W

    更新日期:1987-01-01 00:00:00

  • Procalcitonin in patients with and without immunosuppression and sepsis.

    abstract::High serum levels of procalcitonin (PCT) are observed in patients with sepsis or severe infection. In a prospective study of 122 hospitalised adult medical patients with sepsis, serum PCT was determined on admission and for 9 days thereafter. Patients with no alteration in their immune system showed high PCT values up...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01713044

    authors: al-Nawas B,Shah PM

    更新日期:1996-11-01 00:00:00

  • Correlation between antibiotic consumption and resistance of bloodstream bacteria in a University Hospital in North Eastern Italy, 2008-2014.

    abstract:PURPOSE:The spread of multidrug-resistant bacteria is a worrisome problem worldwide. This study investigated the correlation between antibiotic consumption and antimicrobial resistance trends of the most important bacteria causing bacteremia at the University hospital of Trieste, Italy, from 2008 to 2014. METHODS:Anti...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-0998-z

    authors: Mascarello M,Simonetti O,Knezevich A,Carniel LI,Monticelli J,Busetti M,Schincariol P,Torelli L,Luzzati R

    更新日期:2017-08-01 00:00:00

  • Efficacy and local tolerability of povidone iodine and octenidine hydrochloride solution for the antiseptic preparation of the orificium urethrae.

    abstract::In a randomized clinical study, 61 hospitalized men were examined to test the local tolerability and antimicrobial efficacy of antiseptic treatment of the genitals with povidone iodine versus octenidine hydrochloride solution. Antibacterial efficacy was established by comparing the total aerobic bacterial colony count...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF02560508

    authors: Rudolph P,Fritze F,Reimer K,Klebingat KJ,Kramer A

    更新日期:1999-03-01 00:00:00

  • Colistin and trimethoprim-sulfamethoxazole for the prevention of infection in patients with acute non-lymphocytic leukaemia. Decrease in the emergence of resistant bacteria.

    abstract::In a previous study we demonstrated that trimethoprim-sulfamethoxazole decreases the prevalence of infection in patients with severe granulocytopenia. However, treatment was accompanied by a relatively high incidence of multiresistant microorganisms. We therefore conducted this study to determine whether the addition ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641298

    authors: Rozenberg-Arska M,Dekker AW,Verhoef J

    更新日期:1983-05-01 00:00:00

  • Efficacy of penicillin treatment in purulent maxillary sinusitis. A European multicenter trial.

    abstract::Three hundred and one patients with maxillary sinusitis participated in a double-blind, randomized study at 11 ENT-clinics in Europe. Sinusitis was diagnosed by the presence of at least two signs and symptoms and sinus X-ray showing more than 6 mm swelling of the maxillary mucosa. A microbiological specimen was obtain...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1007/BF01650753

    authors: Nord CE

    更新日期:1988-07-01 00:00:00

  • Thyroiditis due to Brucella melitensis--report of two cases.

    abstract::Two cases of thyroiditis due to Brucella melitensis are reported. Both occurred in foreigners working in Switzerland and presented with characteristic symptoms of thyroiditis which masked those of brucellosis. Cultures were diagnostic. One patient had concomitant thyroid malignancy. Both showed normal thyroid function...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01642110

    authors: von Graevenitz A,Colla F

    更新日期:1990-05-01 00:00:00

  • Comparative trial of trimethoprim and co-trimoxazole in recurrent urinary infections.

    abstract::Eighty-nine patients with a history of recurrent urinary infection who required immediate treatment for significant bacteriuria were treated with either trimethoprim (300 mg at night) or with the standard course of co-trimoxazole (two tablets 12-hourly) for seven days. Cure rates one week after the end of treatment we...

    journal_title:Infection

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01640874

    authors: Brumfitt W,Hamilton-Miller JM,Ludlam H,Damjanovic V,Gargan R

    更新日期:1982-09-01 00:00:00

  • Moxifloxacin vs ampicillin/sulbactam in aspiration pneumonia and primary lung abscess.

    abstract:BACKGROUND:Aspiration pneumonia (AP) and primary lung abscess (PLA), are diseases following aspiration of infectious material from the oropharynx or stomach. An antibiotic therapy, also covering anaerobic pathogens, is the treatment of choice. In this study we compared moxifloxacin (MXF) and ampicillin/sulbactam (AMP/S...

    journal_title:Infection

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s15010-007-7043-6

    authors: Ott SR,Allewelt M,Lorenz J,Reimnitz P,Lode H,German Lung Abscess Study Group.

    更新日期:2008-02-01 00:00:00

  • Seroprevalence of Chlamydia pneumoniae antibodies in a young adult population sample living in Verona. European Community Respiratory Health Survey (ECRHS) Verona.

    abstract:UNLABELLED:The aim of the study was to evaluate the prevalence of antibodies to Chlamydia pneumoniae in a random population sample of 369 young adults (aged 20-44 years), living in Verona, Italy. IgG and IgM titers were measured by micro-immunofluorescence. IgG antibodies, greater or equal to 16, were found in 104/177 ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s150100050009

    authors: Ferrari M,Poli A,Olivieri M,Tardivo S,Biasin C,Balestreri F,Dal Molin G,Lo Cascio V,Campello C

    更新日期:2000-01-01 00:00:00

  • Late-onset cytomegalovirus infection complicated by Guillain-Barre syndrome in a kidney transplant recipient: case report and review of the literature.

    abstract::Cytomegalovirus (CMV) infection remains a common infection after solid-organ transplantation. In the general population CMV disease is associated with Guillain-Barre syndrome (GBS), an autoimmune disease leading to an acute peripheral neuropathy, in 1 of 1000 cases. Interestingly, GBS is a rarely observed complication...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-015-0819-1

    authors: Shaban E,Gohh R,Knoll BM

    更新日期:2016-04-01 00:00:00

  • Correction to: Mucormycosis in hospitalized patients at a tertiary care center in Lebanon: a case series.

    abstract::The spelling of the name "Ali Bazarbachi" was incorrect. ...

    journal_title:Infection

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s15010-018-1203-8

    authors: El Zein S,El-Sheikh J,Zakhem A,Ibrahim D,Bazarbachi A,Kanj SS

    更新日期:2018-12-01 00:00:00

  • Invasive listeriosis in a patient with several episodes of antibiotic associated colitis presumably due to Clostridium difficile.

    abstract::A 62-year-old man developed a blood stream infection and meningitis due to Listeria monocytogenes, 20 days after an episode of pseudo-membranous colitis. The patient, hospitalized for the first time for transurethral prostatectomy, was readmitted 20 days later with watery diarrhea. Pseudo-membranous colitis was diagno...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-1013-4

    authors: Carannante N,Pagliano P,Rossi M,Attanasio V,Rescigno C,Corte L,Tascini C,Cardinali G

    更新日期:2017-06-01 00:00:00

  • Fusobacterium nucleatum prosthetic hip infection in an adult with sickle cell-beta thalassemia.

    abstract::Fusobacterium nucleatum is an anaerobic Gram-negative bacillus commensal to the human oropharynx and gastrointestinal tract which causes an array of human infection, yet it has never been associated with infection of prosthetic joints. We report the first case of prosthetic hip infection caused by F. nucleatum in a ma...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-011-0197-2

    authors: Verma K,McNabb PC,Kurtz W,Green J,Trabue CH

    更新日期:2012-06-01 00:00:00

  • Efficacy of clarithromycin in preventing viridans streptococcal bacteremia following autologous stem cell transplantation.

    abstract:BACKGROUND:In a study involving 200 patients, we previously found that 17.5% of patients developed viridans streptococcal (VS) bacteremia following autologous peripheral blood stem cell transplantation (aPBSCT) when ciprofloxacin or ciprofloxacin plus ampicillin was used for prophylaxis. PATIENTS AND METHODS:A retrosp...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-001-1028-7

    authors: Naqvi B,Dorsky D,Ali SA,Feingold JM,Edwards RL,Bona RD,Clive J,Tutschka PJ,Bilgrami S

    更新日期:2001-08-01 00:00:00

  • [Comparison of the adverse effect profile of different substances such as penicillins, tetracyclines, sulfonamides and quinolones].

    abstract::The penicillins, the tetracyclines and the sulfonamides have often been used in the last few decades in spite of their well-known side effects. Hypersensitivity reactions to penicillins are among the most important adverse reactions in these antibiotics; in every case a careful medical history has to be taken before a...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/BF01644730

    authors: Keller H

    更新日期:1991-01-01 00:00:00

  • Ototoxicity and nephrotoxicity of netilmicin.

    abstract::Comparative functional and histological tests were performed in eight groups of ten quinea pigs each, which were administered 50, 75, 100 and 150 mg of netilmicin respecitvely b.i.d. for 29 days, 15 and 25 mg of gentamicin and 50 and 100 mg of amikacin per kg body weight respecitvely b.i.d. and in one control group of...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01638926

    authors: Federspil P

    更新日期:1976-01-01 00:00:00