Vitamin K supplementation during prophylactic use of cefoperazone in urologic surgery.


:Cefoperazone, an antibiotic commonly used for prophylaxis of infection, has been associated with hypoprothrombinemia and bleeding. To reduce the risk of bleeding, co-administration of vitamin K has been advised. We reassessed the need for vitamin K use in a retrospective analysis of 50 patients undergoing urologic procedures and who had received cefoperazone for three days to prevent infection. Eleven of 50 patients were given vitamin K because of liver or renal disease. Prothrombin time was not elevated in any of the 50 patients analyzed. We conclude that routine use of vitamin K with cefoperazone for perioperative prophylaxis of infection may be unwarranted in patients without identified risk for bleeding.






Rockoff SD,Blumenfrucht MJ,Irwin RJ Jr,Eng RH





Has Abstract


1992-05-01 00:00:00












  • Optimal duration of antimicrobial therapy for uncomplicated Gram-negative bloodstream infections.

    abstract:PURPOSE:Optimal antimicrobial treatment duration for Gram-negative bloodstream infection (BSI) remains unclear. This retrospective cohort study examined effectiveness of short (7-10 days) and long (>10 days) courses of antimicrobial therapy for uncomplicated Gram-negative BSI. METHODS:Hospitalized adults with uncompli...


    pub_type: 杂志文章


    authors: Nelson AN,Justo JA,Bookstaver PB,Kohn J,Albrecht H,Al-Hasan MN

    更新日期:2017-10-01 00:00:00

  • Efficacy and effects on pulmonary function tests of weekly 600 mg aerosol pentamidine as prophylaxis against Pneumocystis carinii pneumonia.

    abstract::A prospective study was designed to evaluate the efficacy and effects on pulmonary function tests of weekly 600 mg aerosolised pentamidine as prophylaxis against Pneumocystis carinii pneumonia (PCP) amongst two groups of patients infected with the human immunodeficiency virus. Group 1 (primary prophylaxis) consisted o...


    pub_type: 临床试验,杂志文章


    authors: Ong EL,Dunbar EM,Mandal BK

    更新日期:1992-05-01 00:00:00

  • Treatment of Lyme arthritis.

    abstract::The efficacy of different therapeutic regimens for Lyme arthritis is reviewed. The first treatment for Lyme arthritis, intramuscular benzathine penicillin 2.4 million units weekly for 3 weeks, had a success rate of 35%. Another study employed intravenous penicillin G at a dosage of 20 million units daily for 10 days, ...


    pub_type: 杂志文章,评审


    authors: Cimmino MA,Moggiana GL,Parisi M,Accardo S

    更新日期:1996-01-01 00:00:00

  • Development of sulphonamide-trimethoprim combinations for urinary tract infections. Part 2: Comparative pharmacokinetics of five sulphonamides.

    abstract::The pharmacokinetics and renal excretion of the sulphonamides sulphachloropyridazine, sulphadiazine, sulphaisodimidine, sulphamerazine, and sulphamethoxazole were investigated in a cross-over study with doses of 800 mg each. The serum half-life, urine levels, distribution volume, protein binding and potential antibact...


    pub_type: 杂志文章


    authors: Ortengren B,Fellner H,Bergan T

    更新日期:1979-01-01 00:00:00

  • Congenital rubella syndrome after maternal reinfection.

    abstract::This report concerns a case of congenital rubella syndrome (CRS) with atypical immune response affecting an infant whose mother had repeated evidence of immunity before pregnancy. Laboratory diagnosis of CRS could only clearly be achieved by virus isolation after the second month of life despite typical clinical featu...


    pub_type: 杂志文章


    authors: Weber B,Enders G,Schlösser R,Wegerich B,Koenig R,Rabenau H,Doerr HW

    更新日期:1993-03-01 00:00:00

  • Phlebitis rate and time kinetics of short peripheral intravenous catheters.

    abstract:BACKGROUND:An observational prospective cohort study was carried out on complication rates and time kinetics of phlebitis caused by short peripheral intravenous catheters (PIVCs) in inpatients on 15 hospital wards in four hospitals in Cologne, Germany. PATIENTS AND METHODS:We observed 1,582 patients with 2,495 PIVCs d...


    pub_type: 杂志文章,多中心研究


    authors: Grüne F,Schrappe M,Basten J,Wenchel HM,Tual E,Stützer H,Cologne Quality Control Network.

    更新日期:2004-02-01 00:00:00

  • Risk factors for bacteriuria with carbapenem-resistant Klebsiella pneumoniae and its impact on mortality: a case-control study.

    abstract:BACKGROUND:The objective of this study was to evaluate the mortality of and risk factors for bacteriuria due to carbapenem-resistant Klebsiella pneumoniae (CRKp) versus carbapenem-susceptible K. pneumoniae (CSKp) producing extended spectrum β lactamase (ESBL). METHODS:This was a retrospective case-control study in whi...


    pub_type: 杂志文章


    authors: Shilo S,Assous MV,Lachish T,Kopuit P,Bdolah-Abram T,Yinnon AM,Wiener-Well Y

    更新日期:2013-04-01 00:00:00

  • Comparison of BacT/Alert blood culture bottles with lytic media for culture of peritoneal dialysis fluid.

    abstract::A comparison was made between the Septi-Chek "Release" system containing saponins, standard BacT/Alert blood culture bottles and FAN BacT/Alert blood culture bottles for culturing CAPD fluids. Seventy-seven CAPD effluent specimens were tested. No differences could be found. Therefore, lytic agents are not necessary wh...


    pub_type: 杂志文章


    authors: Wüst J,von Graevenitz A

    更新日期:1995-11-01 00:00:00

  • In vitro testing of clarithromycin in combination with ethambutol and rifampicin against Mycobacterium avium complex.

    abstract::The activity of clarithromycin in combination with ethambutol and rifampicin was tested at concentrations achievable in serum against 20 strains of Mycobacterium avium complex. The combination of clarithromycin plus rifampicin showed inhibition of 11 of the strains and bactericidal synergism against seven of the strai...


    pub_type: 杂志文章


    authors: Stauffer F,Dörtbudak O,Lahonik E

    更新日期:1991-09-01 00:00:00

  • Prolonged application of closed in-line suction catheters increases microbial colonization of the lower respiratory tract and bacterial growth on catheter surface.

    abstract:BACKGROUND:Microorganisms become attracted to polymer surfaces for a number of reasons including positive charge of biomaterial or concentration of nutrients on the biomaterial surface. Many bacteria additionally possess specific receptors for the interaction with extracellular host protein components that adhere on th...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Freytag CC,Thies FL,König W,Welte T

    更新日期:2003-01-01 00:00:00

  • In-vitro susceptibility of cefoperazone-susceptible and -resistant gram-negative rods to cefoperazone plus sulbactam, other beta-lactams, aminoglycosides and quinolone.

    abstract::We compared the in-vitro activity of cefoperazone-sulbactam (2:1), other beta-lactams, amino-glycosides and ciprofloxacin against cefoperazone-susceptible and -resistant nosocomial gram-negative bacilli. Resistant isolates including Pseudomonas aeruginosa were susceptible to cefoperazone-sulbactam; the susceptible iso...


    pub_type: 杂志文章


    authors: Chandrasekar PH,Sluchak JA

    更新日期:1991-01-01 00:00:00

  • Thrombocytosis associated with acute osteomyelitis.

    abstract::Thrombocytosis is rarely observed during infection. We are describing a patient with acute osteomyelitis and bacteremia who developed thrombocytosis. In the patient described the platelet count paralleled the activity of the infection and the response to therapy. The causes of thrombocytosis and its implications are b...


    pub_type: 杂志文章


    authors: Robey C,Chmel H

    更新日期:1984-11-01 00:00:00

  • The frequency of Mycoplasma pneumoniae antibodies in a Calabrian population.

    abstract::The epidemiological survey was carried out in a Calabrian population in order to ascertain the incidence of antibodies to Mycoplasma pneumoniae. In the past it has been felt that this infection does not occur in Southern Italy. We have found an incidence in our survey equal to that of the other countries. It was impos...


    pub_type: 杂志文章


    authors: Calisto ML,Farina W,Picerno I,Ceccarelli G

    更新日期:1976-01-01 00:00:00

  • Documented cutaneous loxoscelism in the south of France: an unrecognized condition causing delay in diagnosis.

    abstract:BACKGROUND:Loxoscelism is an envenomation due to a bite by spiders of the genus Loxosceles, very well known on the American continent but unrecognized in Europe. CASE REPORT:We report the case of a 36-year-old woman, without any medical history or treatment, who went to a University Hospital in the South of France, fo...


    pub_type: 杂志文章


    authors: Rubenstein E,Stoebner PE,Herlin C,Lechiche C,Rollard C,Laureillard D,Sotto A

    更新日期:2016-06-01 00:00:00

  • Diagnosis of nontuberculous mycobacterial disease in the era of surveillance chest CT scans.

    abstract::The radiologic surveillance of smokers with low-dose CT scan has led to a significant surge of radiologic incidental findings, including the detection of early stages of pulmonary infections including nontuberculous mycobacteria (NTM). This causes a state of overdiagnosis and potential overtreatment of NTM lung diseas...


    pub_type: 杂志文章


    authors: Calzadilla A,Holt G,Campos M,Mirsaeidi M

    更新日期:2018-12-01 00:00:00

  • [Erythromycin determination in organ tissues (author's transl)].

    abstract::The recovery rates of erythromycin after in vitro and in vivo administration were studied comparatively in liver, lung, and kidney. Using buffer standards the recovery rate in homogenates of in vitro administered erythromycin decreased with increasing protein concentration. At constant protein concentration the erythr...


    pub_type: 杂志文章


    authors: Dette GA,Finke U

    更新日期:1979-01-01 00:00:00

  • [Microbiological diagnosis of septicemia].

    abstract::To detect microorganisms in the blood it is necessary not only that the microbiologist uses reliable methods, but also that the clinician takes a sufficient number of blood samples at the right point in time using a correct method for drawing the blood. The best results are obtained if the blood sample is transferred ...


    pub_type: 杂志文章


    authors: Rotter M

    更新日期:1977-03-01 00:00:00

  • Alpha-hemolytic streptococci: a major pathogen of iatrogenic meningitis following lumbar puncture. Case reports and a review of the literature.

    abstract::Iatrogenic meningitis following lumbar puncture is a rare complication of myelography, spinal anesthesia, intrathecal chemotherapy, and epidural anesthesia. Sporadic cases and clusters of iatrogenic meningitis have been reported after intrathecal therapy, but most incidental cases are reported after myelography. Four ...


    pub_type: 杂志文章,评审


    authors: Schneeberger PM,Janssen M,Voss A

    更新日期:1996-01-01 00:00:00

  • [Patient-oriented hospital hygiene (author's transl)].

    abstract::Primary objective of patient-oriented hospital hygiene is the reduction in frequency of the five most important nosocomial infections: urinary tract infection, wound infection, respiratory tract infection, sepsis and infection of the skin and subcutaneous tissue. The less the effect of individual measures on the rate ...


    pub_type: 杂志文章


    authors: Daschner F

    更新日期:1980-01-01 00:00:00

  • Influence of intimal Chlamydophila pneumoniae persistence on cardiovascular complications after coronary intervention.

    abstract:PURPOSE:Chlamydophila pneumoniae has been implicated in atherosclerosis/restenosis; however, clear evidence is missing. Therefore, the aim of our study was to examine the influence of intimal infection and systemic inflammation on cardiovascular complications after coronary intervention. METHODS:45 atheroma specimens ...


    pub_type: 杂志文章


    authors: Tuleta I,Reek D,Braun P,Bauriedel G,Nickenig G,Skowasch D,Andrié R

    更新日期:2015-02-01 00:00:00

  • Influence of cefodizime on the reagibility of human leukocytes.

    abstract::Cefodizime was evaluated for its effect on a number of parameters of leukocyte function in humans. Four healthy volunteers received 2 g i.v. b.i.d. for seven days. Leukocyte activity was measured before, during and after treatment. Using opsonized zymosan as a stimulant, no effect on the respiratory burst of granulocy...


    pub_type: 杂志文章


    authors: Limbert M,Müllner H,Shah PM

    更新日期:1992-01-01 00:00:00

  • In vitro-activity of clavulanic acid and amoxicillin combined against amoxicillin-resistant bacteria.

    abstract::The ability of clavulanic acid to inactivate beta-lactamase was investigated using 47 amoxicillin-resistant bacteria. In the presence of 10 mg/l clavulanic acid most strains of staphylococci, Escherichia coli, Klebsiella and Proteus mirabilis became fully amoxicillin-sensitive. This effect of clavulanic acid was in mo...


    pub_type: 杂志文章


    authors: Peters G,Pulverer G,Neugebauer M

    更新日期:1980-01-01 00:00:00

  • Seroprevalence of Chlamydia pneumoniae antibodies in a young adult population sample living in Verona. European Community Respiratory Health Survey (ECRHS) Verona.

    abstract:UNLABELLED:The aim of the study was to evaluate the prevalence of antibodies to Chlamydia pneumoniae in a random population sample of 369 young adults (aged 20-44 years), living in Verona, Italy. IgG and IgM titers were measured by micro-immunofluorescence. IgG antibodies, greater or equal to 16, were found in 104/177 ...


    pub_type: 杂志文章


    authors: Ferrari M,Poli A,Olivieri M,Tardivo S,Biasin C,Balestreri F,Dal Molin G,Lo Cascio V,Campello C

    更新日期:2000-01-01 00:00:00

  • Update on the "Choosing Wisely" initiative in infectious diseases in Germany.

    abstract:PURPOSE:The Choosing Wisely® initiative is an international campaign addressing over- and underuse of diagnostic and therapeutic measures in infectious diseases among others. Since 2016, the German Society for Infectious Diseases (DGI) has constantly designed new items in this regard. Here we report the most recent rec...


    pub_type: 杂志文章


    authors: Draenert R,Jung N,Choosing Wisely (Klug entscheiden) DGI Working Group.

    更新日期:2020-06-01 00:00:00

  • Safety and immunogenicity of an inactivated hepatitis A vaccine in children 2 to 5 years old.

    abstract::The reactogenicity and immunogenicity of an inactivated hepatitis A vaccine were assessed. Seventy healthy children aged between 2 and 5 years old, who lacked antibodies against the hepatitis A virus, were enrolled in this study. With a 0-, 1-, and 6-month vaccination schedule, the children received three doses of 360...


    pub_type: 临床试验,杂志文章


    authors: Arístegui J,Morales JL,Dal-Ré R,González A,Gallego MS,Garrote E

    更新日期:1995-09-01 00:00:00

  • Emergency endovascular stent-grafting for infected pseudoaneurysm of brachial artery.

    abstract::The use of covered stents in an infected field is controversial. It is generally recommended that infected aneurysms be treated using autografts or allografts. We report a case of infected brachial pseudoaneurysms that developed after medical debridement of a methicillin-resistant Staphylococcus aureus (MRSA)-infected...


    pub_type: 杂志文章


    authors: Kurimoto Y,Tsuchida Y,Saito J,Yama N,Narimatsu E,Asai Y

    更新日期:2003-06-01 00:00:00

  • Acinetobacter septicemia: a threat to neonates? Special aspects in a neonatal intensive care unit.

    abstract::Acinetobacter is one of the organisms responsible for nosocomial infections in intensive care, neurosurgery, burn and hemodialysis units. There are only a few reports on Acinetobacter infections in neonatal intensive care units. Over a 31 month period, nine cases of Acinetobacter sepsis occurred in our unit, with four...


    pub_type: 杂志文章


    authors: Regev R,Dolfin T,Zelig I,Givoni S,Wolach B

    更新日期:1993-11-01 00:00:00

  • Findings from an outbreak of carbapenem-resistant Klebsiella pneumoniae emphasize the role of antibiotic treatment for cross transmission.

    abstract:PURPOSE:In January 2015, we noticed by rectal swab analyses that seven of 23 patients at an early rehabilitation ward had been colonized with carbapenem-resistant Klebsiella pneumoniae (CKP). Here, we describe risk factors for CKP acquisition. METHODS:In the present study, the outbreak is described and risk factors fo...


    pub_type: 杂志文章


    authors: Borgmann S,Pfeifer Y,Becker L,Rieß B,Siegmund R,Sagel U

    更新日期:2018-02-01 00:00:00

  • Intestinal microsporidiosis in patients with acquired immunodeficiency syndrome--report of three more German cases.

    abstract::Intestinal microsporidiosis with Enterocytozoon bieneusi was diagnosed in three of 18 HIV-infected patients with chronic diarrhoea. In two cases all known stages of the life cycle of E. bieneusi (merogonial plasmodia, sporogonial plasmodia, sporoblasts, spores) were found in duodenal biopsies by electron microscopical...


    pub_type: 杂志文章,评审


    authors: Franzen C,Fätkenheuer G,Salzberger B,Müller A,Mahrle G,Diehl V,Schrappe M

    更新日期:1994-11-01 00:00:00

  • Potential role of post-transplant hypogammaglobulinemia in the risk of Clostridium difficile infection after kidney transplantation: a case-control study.

    abstract:PURPOSE:To identify reversible risk factors for Clostridium difficile infection (CDI) after kidney transplantation (KT) that could lead to a reduction in its incidence and associated complications. METHODS:We performed a single-center case-control study in which 41 patients undergoing KT between February 2009 and July...


    pub_type: 杂志文章


    authors: Origüen J,Fernández-Ruiz M,Lumbreras C,Orellana MÁ,López-Medrano F,Ruiz-Merlo T,San Juan R,García-Reyne A,González E,Polanco N,Paz-Artal E,Andrés A,Aguado JM

    更新日期:2015-08-01 00:00:00