[Evaluation of the development of resistance as a factor for the limitation of therapeutic possibilities].

abstract：:Campylobacter jejuni (previously called "related vibrio") has recently become recognized as an important cause of acute diarrhoeal disease in many countries. As with other intestinal pathogens, the clinical picture of C. jejuni infection varies from symptomless excretion to severe disease. The incubation period averag...

journal_title：Infection

authors： Butzler JP

更新日期：1982-01-01 00:00:00

abstract：:Drug interactions are an important and emerging problem in the treatment of HIV-infected patients. Protease inhibitors, like nonnucleoside reverse transcriptase inhibitors, are metabolized by the cytochrome P-450 enzyme system and each of these antiretroviral agents may interact with other drugs metabolized by this sy...

journal_title：Infection

authors： Lanzafame M,Trevenzoli M,Faggian F,Marcati P,Gatti F,Carolo G,Concia E

更新日期：2002-01-01 00:00:00

abstract：:In this review the pharmacokinetic properties of trimethoprim (TMP) and TMP/sulphonamide combinations are discussed. The concentration of both substances in the various body fluids and tissues differ considerably from the concentrations in blood due to the different distribution of TMP and sulphonamides in the body. A...

journal_title：Infection

authors： Reeves DS,Wilkinson PJ

更新日期：1979-01-01 00:00:00

abstract：:Polymerase chain reaction (PCR) analysis with primers for the pp65, a-sequence, glycoprotein B, and major immediate early genes of human cytomegalovirus (CMV) was used to study five congenitally-infected infants and their CMV-infected family members. Family members excreting CMV included three mothers and two siblings...

journal_title：Infection

authors： Souza IE,Gregg A,Pfab D,Dawson JD,Benson P,O'Neill ME,Murph JR,Petheram SJ,Bale JF Jr

更新日期：1997-05-01 00:00:00

abstract：:Experimental infections in animals and their chemotherapy are dependent on a variety of experimental conditions and parameters which may be themselves interrelated; the type and number of infecting organisms, the nature of the infection, the antibiotic chosen for therapy and its administration schedule can influence t...

journal_title：Infection

authors： Rolinson GN

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:This open, randomized, controlled study [208136/018] assessed the safety and immunogenicity of early vaccination with an experimental tetravalent measles-mumps-rubella-varicella (MMRV) vaccine (GlaxoSmithKline Biologicals) compared to concomitant administration of separate licensed MMR (Priorix) and varicell...

journal_title：Infection

authors： Goh P,Lim FS,Han HH,Willems P

更新日期：2007-10-01 00:00:00

abstract：:Influenza viruses type A and B can cause a wide spectrum of illness, and they are responsible for considerable mortality and morbidity. With the new neuraminidase inhibitors, of which zanamivir was the first drug to be licensed, the physician has antivirals at his disposal which are safe and effective against both inf...

journal_title：Infection

authors： Wutzler P,Vogel G

更新日期：2000-09-01 00:00:00

abstract：PURPOSE:For simultaneous detection of Borrelia miyamotoi (relapsing fever spirochete) and Borrelia burgdorferi sensu lato, we have developed a duplex real-time PCR targeting the flagellin gene (flaB; p41), a locus frequently used in routine diagnostic PCR for B. burgdorferi s.l. detection. METHODS:Primers and probes w...

journal_title：Infection

authors： Venczel R,Knoke L,Pavlovic M,Dzaferovic E,Vaculova T,Silaghi C,Overzier E,Konrad R,Kolenčík S,Derdakova M,Sing A,Schaub GA,Margos G,Fingerle V

更新日期：2016-02-01 00:00:00

abstract：:Interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), interleukin-8 (IL-8) and tumor necrosis factor alpha (TNF) are important mediators of fever and inflammation, and are involved in the pathogenesis of sepsis. There is only limited data on serum concentrations of these proinflammatory cytokines in patients with feve...

journal_title：Infection

authors： Engel A,Kern WV,Mürdter G,Kern P

更新日期：1994-05-01 00:00:00

abstract：:The minimal inhibitory concentrations of ceftizoxime, cefotaxime, moxalactam, cefoperazone, cefotiam and cefamandole were determined against various species of gram-negative bacteria and against Staphylococcus aureus. Ceftizoxime was more active against Enterobacteriaceae than cefamandole, cefotiam and cefoperazone an...

journal_title：Infection

authors： Husson MO,Courcol R,Izard D,Leclerc H

更新日期：1984-01-01 00:00:00

abstract：:A comparison was made between the Septi-Chek "Release" system containing saponins, standard BacT/Alert blood culture bottles and FAN BacT/Alert blood culture bottles for culturing CAPD fluids. Seventy-seven CAPD effluent specimens were tested. No differences could be found. Therefore, lytic agents are not necessary wh...

journal_title：Infection

authors： Wüst J,von Graevenitz A

更新日期：1995-11-01 00:00:00

abstract：:The outer membrane proteins, F, H2 and I, from PA12 strain of Pseudomonas aeruginosa, were purified and used successfully for immunization of Balb/c mice. The immunized mice were protected against challenge with a 2-26 fold LD50 of all known 19 serogroups of P. aeruginosa. ...

journal_title：Infection

authors： von Specht BU,Strigl G,Ehret W,Brendel W

更新日期：1987-01-01 00:00:00

abstract：:At present, there is no definitive antiviral treatment for coronavirus disease 2019 (COVID-19). We describe our early experience with remdesivir in four critically ill COVID-19 patients. Patients received a 200 mg loading dose, followed by 100 mg daily intravenously for up to 10 days. All patients had been previously ...

journal_title：Infection

authors： Durante-Mangoni E,Andini R,Bertolino L,Mele F,Florio LL,Murino P,Corcione A,Zampino R

更新日期：2020-10-01 00:00:00

abstract：:Between 1 November 1993 and 31 October 1996, admissions to paediatric departments for Bordetella pertussis complications were reported to a nationwide, hospital-based active surveillance system. The case definition included pertussis complicated by pneumonia, apnoea requiring assisted ventilation, seizures, encephalop...

journal_title：Infection

authors： Herzig P,Hartmann C,Fischer D,Weil J,von Kries R,Giani G,Schroten H,Wirsing von König CH

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:Although limited data exist on the efficacy and potential risk of synergistic aminoglycoside therapy for persistent Staphylococcus aureus bacteremia and endocarditis, aminoglycosides are frequently used in clinical practice. METHODS:As our study population, we included subjects fulfilling the modified Duke cri...

journal_title：Infection

authors： Lemonovich TL,Haynes K,Lautenbach E,Amorosa VK

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:Myopia is a prevalent condition among Asians. Orthokeratology lens has gained popularity as a method of myopia control. This systematic review is to summarize the clinical profile of infectious keratitis in association with orthokeratology lens wear. METHODS:We searched in the PubMed and EMBASE for articles ad...

journal_title：Infection

authors： Kam KW,Yung W,Li GKH,Chen LJ,Young AL

更新日期：2017-12-01 00:00:00

abstract：:Intestinal microsporidiosis with Enterocytozoon bieneusi was diagnosed in three of 18 HIV-infected patients with chronic diarrhoea. In two cases all known stages of the life cycle of E. bieneusi (merogonial plasmodia, sporogonial plasmodia, sporoblasts, spores) were found in duodenal biopsies by electron microscopical...

journal_title：Infection

authors： Franzen C,Fätkenheuer G,Salzberger B,Müller A,Mahrle G,Diehl V,Schrappe M

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Rotavirus is the major cause of gastroenteritis in children throughout the world. Every year, a large number of children aged < 5 years die from rotavirus-related diarrhoeal diseases. Though these infections are vaccine-preventable, the vast majority of children in low-income countries suffer from the infect...

journal_title：Infection

authors： Mahmud-Al-Rafat A,Muktadir A,Muktadir H,Karim M,Maheshwari A,Ahasan MM

更新日期：2018-02-01 00:00:00

abstract：:The incidence of urinary tract infections (UTI) in 299 renal graft transplantations (281 patients) was analyzed. UTI episodes were demonstrated in 185 grafts (62%), most frequently in the first month after transplantation. The infectious episodes were mostly recurrent. Persistent infection, detected in 11% of grafts, ...

journal_title：Infection

authors： Prát V,Horcicková M,Matousovic K,Hatala M,Liska M

更新日期：1985-09-01 00:00:00

abstract：:The serum IL-6 and TNF alpha response to cardiopulmonary bypass surgery was studied in 12 patients. Human neutrophil elastase was also measured in order to detect the presence of neutrophil activation. Peripheral venous blood samples were obtained before, during, and 1, 2, 3 and 6 days after surgery. Intra-operative s...

journal_title：Infection

authors： Holzheimer RG,Molloy RG,Görlach H,Wilkert S,Hehrlein F

更新日期：1994-01-01 00:00:00

abstract：:The clinical symptoms of urinary tract infections (UTI) are only rarely an indication of the presence of the disease in childhood. Of decisive importance for the detection of UTI is an appropriate investigation to determine whether there is significant bacteriuria. Since in a significant proportion of cases of UTI in ...

journal_title：Infection

authors： Straub E

更新日期：1979-01-01 00:00:00

abstract：:Bacterial meningitis of infants and children exact a major toll worldwide. Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis continue to be the major causes, and efforts to reduce the incidence of this disease have had limited success. Major advances in rapid diagnosis, such as antigen detect...

journal_title：Infection

authors： Marks MI

更新日期：1984-01-01 00:00:00

abstract：:The MICs and MBCs of mecillinam, ticarcillin, mezlocillin, azlocillin and piperacillin were determined by the microdilution method in liquid medium using 700 strains of gram-negative bacilli and enterococci isolated from pathological sources and classified as a function of their sensitivity to ampicillin and carbenici...

journal_title：Infection

authors： Thabaut A,Durosoir JL,Saliou P

更新日期：1982-01-01 00:00:00

abstract：:In a previous study we demonstrated that trimethoprim-sulfamethoxazole decreases the prevalence of infection in patients with severe granulocytopenia. However, treatment was accompanied by a relatively high incidence of multiresistant microorganisms. We therefore conducted this study to determine whether the addition ...

journal_title：Infection

authors： Rozenberg-Arska M,Dekker AW,Verhoef J

更新日期：1983-05-01 00:00:00

abstract：:The in vitro sensitivities of 47 multi-resistant gram-negative bacilli against six third generation cephalosporins were investigated. Overall, moxalactam was the most active compound and cefoperazone the least active. Ceftizoxime and ceftazidime were very active against Enterobacteriaceae. Ceftriaxone and ceftizoxime ...

journal_title：Infection

authors： Fainstein V,Le Blanc B,Bodey GP

更新日期：1983-01-01 00:00:00

abstract：:Twenty-four homosexual adult patients suffering from LAS or AIDS were investigated for immunoglobulin class- and IgG subclass-specific antibodies to human immunodeficiency virus (HIV) by the indirect ELISA and Western blot using monoclonal tracer antibodies. All patients revealed HIV-specific serum antibodies of IgG s...

journal_title：Infection

authors： Mergener K,Enzensberger W,Rübsamen-Waigmann H,von Briesen H,Doerr HW

更新日期：1987-01-01 00:00:00

abstract：:Cydnidae bug (also termed the burrowing bug) are arthropods of the order Hemiptera, that are recognized by their morphological adaptations for digging. They release an odorous substance from special glands that serve as self-defense, causing pigmented macules when in contact with human skin, especially during the rain...

journal_title：Infection

authors： Chakraborty S,Sil A,Panigrahi A

更新日期：2020-07-11 00:00:00

abstract：PURPOSE:The main purpose of this study was to examine the overall distribution of chronic comorbidities in coronavirus disease-19 (COVID-19) infected populations and the risk of the underlying burden of disease in terms of the case fatality ratio (CFR). METHODS:We carried out a systematic review and meta-analysis of s...

journal_title：Infection

authors： Mahumud RA,Kamara JK,Renzaho AMN

更新日期：2020-12-01 00:00:00

abstract：:Drug-induced anaphylaxis is an unpredictable adverse reaction. Although it may occur with any medication, antibiotics induce more cases of anaphylaxis than any other medication class with most cases being induced by β-lactam antibiotics. Clindamycin is an antibiotic with good gram-positive and anaerobe coverage which ...

journal_title：Infection

authors： Bulloch MN,Baccas JT,Arnold S

更新日期：2016-06-01 00:00:00

abstract：:Combinations of amoxicillin and clavulanic acid were tested against 11 Escherichia coli strains and five Klebsiella aerogenes strains. Apart from one E. coli, the strains were highly resistant to amoxicillin due to beta-lactamase production. Synergy was demonstrated in all strains by agar dilution. Synergy was detecte...

journal_title：Infection

authors： Fuglesang JE,Bergan T

更新日期：1983-11-01 00:00:00