Abstract:
:We analyzed the expression of aquaporins (AQPs) in the small intestine to elucidate their functions, and found that AQP9, which had not previously been detected there, is present in duodenum, jejunum, and ileum. AQP9 is expressed in colon as well, but not in stomach. Also, its expression in these intestinal sections is limited to the basolateral membranes of a goblet cell subset. Our finding that AQP9 is present specifically in goblet cells as mucus-secreting cells suggests its involvement in the synthesis and/or secretion of a certain kind of mucus which may protect the intestinal surface and smooth the flow of intestinal contents.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Okada S,Misaka T,Matsumoto I,Watanabe H,Abe Kdoi
10.1016/s0014-5793(03)00256-4keywords:
subject
Has Abstractpub_date
2003-04-10 00:00:00pages
157-62issue
1-3eissn
0014-5793issn
1873-3468pii
S0014579303002564journal_volume
540pub_type
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