Abstract:
:Macrophages contain arginase and an inducible NO synthase, demonstrated by using L-arginine, the common substrate, for production of both nitric oxide and urea. Arginase was inhibited by nitrite, the stable end product of NO. This inhibition was non-competitive, and could not be explained by the reaction of nitrite with arginine, or by the irreversible covalent modification of arginase, or by the removal of Mn2+, a cofactor of arginase.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Hrabák A,Bajor T,Temesi A,Mészáros Gdoi
10.1016/0014-5793(96)00659-xsubject
Has Abstractpub_date
1996-07-22 00:00:00pages
203-6issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(96)00659-Xjournal_volume
390pub_type
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