Abstract:
:A concise discussion of the role of different geometrical conformational states in the process of self-assembling of gangliosides is given. The report focuses on the effects of the geometrical variations occurring in the head group region of gangliosides as reflected on the geometrical properties of the whole assembly. Collective phenomena happening at the water interfacial region are found to be coupled to the phase transition of the lipid moiety, that is, to the well-known order-disorder conformational transition involving the hydrophobic tails. The possible biological relevance of the head group bistability is envisaged.
journal_name
Neurochem Resjournal_title
Neurochemical researchauthors
Brocca P,Cantù L,Corti M,Del Favero E,Raudino Adoi
10.1023/a:1020255529125keywords:
subject
Has Abstractpub_date
2002-08-01 00:00:00pages
559-63issue
7-8eissn
0364-3190issn
1573-6903journal_volume
27pub_type
杂志文章,评审abstract::We found that chronic lithium diet affects the sensitivity of neuroleptic receptors and the content of amino acids in the brain, and that the changes in adult animals differ from those in young rats. Pregnant rats were kept on lithium diet (pellets with 0.21% Li2CO3 and 0.21% NaCl) during the gestation period and the ...
journal_title:Neurochemical research
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journal_title:Neurochemical research
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journal_title:Neurochemical research
pub_type: 杂志文章
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abstract::Danhong injection, a Chinese Materia Medica standardized product extracted from Radix Salviae miltiorrhizae and Flos Carthami tinctorii, is used extensively for the treatment of cerebrovascular diseases such as acutely cerebral infarction in clinic. In this study, we further investigated the mechanisms of Danhong inje...
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journal_title:Neurochemical research
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journal_title:Neurochemical research
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journal_title:Neurochemical research
pub_type: 杂志文章,评审
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abstract::Impaired glucose transport across brain tissue barriers causes infantile seizures, developmental delay and acquired microcephaly. Since the first report in 1991 (De Vivo et al, NEJM, 1991) 17 patients have been identified with the glucose transporter protein syndrome (GTPS). The diagnostic feature of the syndrome is a...
journal_title:Neurochemical research
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