Modulation of a neuronal calmodulin mRNA species in the rat brain stem by reserpine.

abstract：:The uptake of radioactive ethanolamine has been studied in exclusively neuronal and glial cell cultures from dissociated cerebral hemispheres of chick embryos. Both cell types show saturable kinetics; neurons have an apparent Km of 6.7 microM, Vmax 41.4 pmol mg prot.-1 min-1 and glial cells a Km of 119.6 microM, Vmax ...

journal_title：Neurochemical research

authors： Massarelli AC,Dainous F,Hoffmann D,Mykita S,Freysz L,Dreyfus H,Massarelli R

更新日期：1986-01-01 00:00:00

abstract：:The effects of vinpocetine on internal Na+ (Na(i)), cAMP accumulation, internal Ca2+ (Ca(i)) and excitatory amino acid neurotransmitters release, under resting and under depolarized conditions, was investigated in rat striatum synaptosomes. Veratridine (20 microM) or high K+ (30 mM) were used as depolarizing agents. R...

journal_title：Neurochemical research

authors： Sitges M,Nekrassov V

更新日期：1999-12-01 00:00:00

abstract：:The aim of this study was to investigate potential therapeutic effects of IFN-γ primed human umbilical cord mesenchymal stem cell (IFN-γ-hUCMSCs) transplantation on experimental autoimmune encephalomyelitis (EAE) in mice. In this study, EAE mouse model was established by MOG35-55 immunization method. Outcomes of the E...

journal_title：Neurochemical research

authors： Zhou X,Liu X,Liu L,Han C,Xie Z,Liu X,Xu Y,Li F,Bi J,Zheng C

更新日期：2020-07-01 00:00:00

abstract：:The study provides detailed biochemical correlates to the common histopathological diagnoses in epilepsy. A dot immunobinding procedure was used for quantification of NSE, GFA, S-100, NCAM, NF 68 and NF 200. The material consisted of samples from 48 patients either selected for surgical treatment of partial epilepsy o...

journal_title：Neurochemical research

authors： Hamberger A,Bock E,Nordborg C,Nyström B,Silfvenius H,Wang S,Haglid KG

更新日期：1993-04-01 00:00:00

abstract：:VGF nerve growth factor inducible (VGF) is a neuropeptide precursor induced by brain-derived neurotrophic factor and nerve growth factor. VGF is increased in the prefrontal cortex and cerebrospinal fluid in schizophrenia patients. In our previous study, VGF-overexpressing mice exhibited schizophrenia-like behaviors an...

journal_title：Neurochemical research

authors： Mizoguchi T,Shimazawa M,Ohuchi K,Kuse Y,Nakamura S,Hara H

更新日期：2019-02-01 00:00:00

abstract：:Metal ions are often used to block calcium channels in various tissues, including synaptosomes. In the present study, Fura-2 was used to determine the effectiveness of various metal ions as calcium channel blockers in rat brain synaptosomes in vitro. In buffer solutions, La3+ and Cd2+ increased the Fura-2 fluorescence...

journal_title：Neurochemical research

authors： Sun YD,Benishin CG

更新日期：1989-11-01 00:00:00

abstract：:Incomplete ischemia of the spinal cord was produced in dogs by 40 min occlusion of the abdominal aorta that was followed by 5-40 min of recirculation. Amino acid incorporation into ribosomes in vitro in the presence of venous blood sera was estimated. The most significant reduction in incorporation was produced by ser...

journal_title：Neurochemical research

authors： Chavko M,Burda J,Marsala J

更新日期：1986-06-01 00:00:00

abstract：:Human neuroblastoma cholinergic LA-N-2 cells were used as an experimental model to test the possibility that the methylation of phosphoethanolamine (PEtn) to phosphocholine (PCho) and free choline (Cho) (Andriamampandry et al. 1989) could contribute to acetylcholine (AcCho) synthesis. LA-N-2 cells were incubated with ...

journal_title：Neurochemical research

authors： Haidar NE,Carrara M,Andriamampandry C,Kanfer JN,Freysz L,Dreyfus H,Massarelli R

更新日期：1994-01-01 00:00:00

abstract：:The real-time iontophoretic method has measured volume fraction and tortuosity of the interstitial component of extracellular space in many regions and under different conditions. To interpret these data computer models of the interstitial space (ISS) of the brain are constructed by representing cells as Basic Cellula...

journal_title：Neurochemical research

authors： Nicholson C,Kamali-Zare P

更新日期：2020-01-01 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder of dopaminergic, noradrenergic, and serotonergic systems, in which dopamine, noradrenaline, and serotonin levels are depleted and lead to the development of motor and non-motor symptoms such as tremor, bradykinesia, weight changes, fatigue, depression, and visua...

journal_title：Neurochemical research

authors： Parambi DGT,Saleem U,Shah MA,Anwar F,Ahmad B,Manzar A,Itzaz A,Harilal S,Uddin MS,Kim H,Mathew B

更新日期：2020-11-01 00:00:00

abstract：:Olfactory ensheathing cells (OECs) and Schwann cells (SCs) are closely-related cell types with regeneration-promoting properties. Comparative gene expression analysis is particularly relevant since it may explain cell type-specific effects and guide the use of each cell type into special clinical applications. In the ...

journal_title：Neurochemical research

authors： Omar M,Hansmann F,Kreutzer R,Kreutzer M,Brandes G,Wewetzer K

更新日期：2013-05-01 00:00:00

abstract：:It is reported that CNS hemorrhage causes membrane dysfunction and may exacerbate this damage as a result of secondary ischemia or hypoxia. Since hyperbaric oxygenation improves oxygen metabolism, it may reduce this membrane damage. The present study was conducted to reveal whether hyperbaric oxygenation influences me...

journal_title：Neurochemical research

authors： Yufu K,Itoh T,Edamatsu R,Mori A,Hirakawa M

更新日期：1993-09-01 00:00:00

abstract：:To study the early effects of neonatal 5,7-dihydroxytryptamine lesions on 5-hydroxytryptamine1A (5-HT1A) receptors, we measured regional [3H]8-OH-DPAT-labeled 5-HT1A sites in binding assays and compared them to our previous studies of [3H]paroxetine-labeled 5-HT transporter sites during the first month in the same rat...

journal_title：Neurochemical research

authors： Pranzatelli MR

更新日期：1994-03-01 00:00:00

abstract：:Crayfish glutamic acid decarboxylase (GAD), like the homologous enzymes from other species, is inhibited by carbonyl-trapping agents (e.g. aminooxyacetic acid; AOAA) and sulfhydryl reagents (e.g. 5,5'-dithiobis-(2-nitrobenzoic acid); DTNB). It also is inhibited by the product GABA, many anions (e.g. SCN- and Cl-), and...

journal_title：Neurochemical research

authors： Grossfeld RM,Yancey SW,Baxter CF

更新日期：1984-07-01 00:00:00

abstract：:The effect of isoproterenol, norepinephrine, dopamine, and serotonin on the accumulation of adenosine 3',5'-monophosphate (cAMP) was studied in homogeneous neuronal cultures from 8-day chick embryo hemispheres. Among the catecholamines, isoproterenol had a more pronounced effect on the accumulation of cAMP. Norepineph...

journal_title：Neurochemical research

authors： Ciesielski-Treska J,Ulrich G

更新日期：1980-10-01 00:00:00

abstract：:A rapid and specific method for assaying 4-aminobutyrate-2-oxoglutarate aminotransferase was developed. The method was based on the selectivity of ion exchange resin and the speed of vacuum filtration. With this new method, the aminotransferase activity in various tissues has been determined as follows: brain, 10.2; s...

journal_title：Neurochemical research

authors： Wu JY,Moss LG,Chude O

更新日期：1978-04-01 00:00:00

abstract：:Epilepsy is one of the oldest neurological conditions known to humankind. It is known that oxidative stress and generation of reactive oxygen species are a cause and consequence of epileptic seizures. Although recent years have seen tremendous progress in the molecular biology and metabolism of selenium, we still know...

journal_title：Neurochemical research

authors： Nazıroglu M

更新日期：2009-12-01 00:00:00

abstract：:Trans-caryophyllene (TC), a component of essential oil found in many flowering plants, has shown its neuroprotective effects in various neurological disorders. However, the effects of TC on epilepsy haven't been reported before. In this study, we investigated the effect of TC on kainic acid-induced seizure activity ca...

journal_title：Neurochemical research

authors： Liu H,Song Z,Liao D,Zhang T,Liu F,Zhuang K,Luo K,Yang L

更新日期：2015-01-01 00:00:00

abstract：:The 7S NGF complex from the male mouse submaxillary gland consists of the alpha, gamma, and beta subunits in the ratio alpha 2 gamma 2 beta. The beta (NGF) subunit contains all the known biolocial activity of 7S NGF. The alpha and gamma subunits are both members of glandular kallikrein gene family, yet only gamma subu...

journal_title：Neurochemical research

authors： Burcham TS,Sim I,Bolin LM,Shooter EM

更新日期：1991-06-01 00:00:00

abstract：:Precise control of the proliferation and differentiation of multipotent neural stem cells (NSCs) is crucial for the proper development of the nervous system. Although cyclinD1 has been implicated as a cause of cancer in many studies, its roles in NSCs remain elusive. In this study, we examined the over-expression of c...

journal_title：Neurochemical research

authors： Ma J,Cui B,Ding X,Wei J,Cui L

更新日期：2015-08-01 00:00:00

abstract：:Glutamine synthetase (GS) is the major glutamine-forming enzyme of vertebrates and is accepted to be a marker of astroglial cells. Maturation of astroglial cells is characterized by an increase of GS activity, and the regulation of this enzyme is the topic of many publications. Because of the fundamental role of the G...

journal_title：Neurochemical research

authors： Haghighat N

更新日期：2005-05-01 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disease, with genetics and environment contributing to the disease onset. The limited pathological cognize of the disease restrained the approaches to improve the clinical treatment. Recently, studies showed that endoplasmic reticulum (ER) stress played an important role...

journal_title：Neurochemical research

authors： Ning B,Deng M,Zhang Q,Wang N,Fang Y

更新日期：2016-08-01 00:00:00

abstract：:Prevention and amelioration of Mibyou (sub-healthy condition) is the critical target for disease prevention including age-related diseases and cancer although the Mibyou condition is not yet pathologically defined. Since the oxidative stress is an underlying basic etiology associated with many diseases and aging, the ...

journal_title：Neurochemical research

authors： Konishi T

更新日期：2009-04-01 00:00:00

abstract：:Hippocampal cells dissociated from 5-day-old rat pups were grown in a suitable chemically defined basal medium, supplemented or not with 3,3',5-triiodo-L-thyronine (T3), [Arg8]-vasopressin (AVP), or both, at different concentrations. Four days after plating, neuron-like cells began to degenerate drastically in the bas...

journal_title：Neurochemical research

authors： Clos J,Gabrion J

更新日期：1989-10-01 00:00:00

abstract：:Salsolinol, an endogenous neurotoxin, is known to be involved in the pathogenesis of Parkinson's disease (PD). In the present study, we have investigated the effects of salsolinol on the activation of two different signaling pathways that involve c-Jun N-terminal kinase (JNK), and nuclear factor-kappaB, (NF-kappaB) in...

journal_title：Neurochemical research

authors： Wanpen S,Kooncumchoo P,Shavali S,Govitrapong P,Ebadi M

更新日期：2007-03-01 00:00:00

abstract：:Ketogenic diet (KD) has been shown to be beneficial in a range of neurological disorders, with ketone metabolite β-hydroxybutyrate (βOHB) reported to block the nucleotide oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome in bone marrow-derived macrophages. In this study, we sh...

journal_title：Neurochemical research

authors： Kong G,Liu J,Li R,Lin J,Huang Z,Yang Z,Wu X,Huang Z,Zhu Q,Wu X

更新日期：2020-10-27 00:00:00

abstract：:This article puts forward the hypothesis that the Low Density Lipid Receptor (LDLR) is one of the molecules that is involved in the clearance of amyloid proteins in the brain and that it may play a role in Alzheimer's Disease (AD) via its up-regulation by statins. The hypothesis is built on the following observations:...

journal_title：Neurochemical research

authors： Abdulkarim Y,Hameed Z

更新日期：2006-06-01 00:00:00

abstract：:In order to investigate the role of two free radical detoxificant enzymes in patients with aging brain disorders, superoxide dismutase (SOD) and catalase (CAT) activities have been measured in blood from male and female human patients of different ages with several types of aging brain disorders. When compared with ac...

journal_title：Neurochemical research

authors： de la Torre MR,Casado A,López-Fernández ME,Carrascosa D,Casado MC,Venarucci D,Venarucci V

更新日期：1996-08-01 00:00:00

abstract：:Single prolonged stress (SPS) is one of the preclinical models of posttraumatic stress disorder (PTSD) in humans. Not every traumatized person develops PTSD and the onset of the disease varies from months to many years after exposure to life-threatening events. The pathogenetic neurometabolites in PTSD have not been i...

journal_title：Neurochemical research

authors： Lim SI,Song KH,Yoo CH,Woo DC,Choe BY

更新日期：2017-08-01 00:00:00

abstract：:The mechanism of focal demyelination in multiple sclerosis has been a long-standing enigma of this disorder. Cytokines, a diverse family of signalling molecules, are viewed as potential mediators of the process based on clinical observations and studies with animal models and tissue/cell culture systems. Myelin and ol...

journal_title：Neurochemical research

authors： Ledeen RW,Chakraborty G

更新日期：1998-03-01 00:00:00