A thyroid hormone-vasopressin interaction promotes survival and maturation of hippocampal neurons dissociated postnatally.

abstract：:Nitric oxide has been strongly implicated in the development of tissue infarction in response to focal cerebral ischemia. Nitric oxide and its derivatives can inhibit components of the electron transport chain, providing a likely target for these substances in ischemic and post-ischemic brain. Lactate content is incre...

journal_title：Neurochemical research

authors： Helps SC,Sims NR

更新日期：2007-04-01 00:00:00

abstract：:Previous studies have shown that hypoxia induces nitric oxide synthase-mediated generation of nitric oxide free radicals leading to peroxynitrite production. The present study tests the hypothesis that hypoxia results in NO-mediated modification of Na+, K+-ATPase in the fetal brain. Studies were conducted in guinea pi...

journal_title：Neurochemical research

authors： Qayyum I,Zubrow AB,Ashraf QM,Kubin J,Delivoria-Papadopoulos M,Mishra OP

更新日期：2001-10-01 00:00:00

abstract：:We examined the impact of peroxiredoxin-I (Prx-I) and peroxiredoxin-II (Prx-II) stable transduction on oxidative stress in PC12 neurons and NIH3T3 fibroblasts and found variability depending on cell type and Prx subtype. In PC12 neurons, Prx-II suppressed reactive oxygen species (ROS) generation by 36% (p < 0.01) rela...

journal_title：Neurochemical research

authors： Simzar S,Ellyin R,Shau H,Sarafian TA

更新日期：2000-12-01 00:00:00

abstract：:The primary objective of this investigation was to assess the neuroprotective efficacy of spice active principles namely Eugenol (Eug) and isoeugenol (IE) in an acrylamide (ACR) neuropathy model in rats. In the present study, ACR administration (50 mg/kg bw, i.p. 3 times/week) for 5 weeks to growing rats caused typica...

journal_title：Neurochemical research

authors： Prasad SN,Muralidhara

更新日期：2013-02-01 00:00:00

abstract：:The effect of maternal hypoxia on the modification of the fetal brain cell membrane N-methyl-D-aspartate (NMDA) receptor and its modulatory sites was investigated. Experiments were conducted in pregnant guinea pigs of 60 days of gestation. Guinea pig fetuses were exposed to maternal hypoxia (FiO2 = 7%) for 60 minutes....

journal_title：Neurochemical research

authors： Mishra OP,Delivoria-Papadopoulos M

更新日期：1992-12-01 00:00:00

abstract：:Acupuncture and moxibustion are traditional medical treatments that have come to play important roles in complementary and alternative medicines. Moxibustion also has a long history as a folk remedy in Japan, particularly due to the technical simplicity and selective efficacy on certain types of disease and distress. ...

journal_title：Neurochemical research

authors： Fukuda F,Shinbara H,Yoshimoto K,Yano T,Kuriyama K

更新日期：2005-12-01 00:00:00

abstract：:CNTF (ciliary neurotrophic factor) has been suggested to be an important survival factor for oligodendrocytes; however, this effect is inconsistently obtained and myelination appears normal in CNTF null animals. On the other hand, CNTF stimulates astrocytes to produce growth and trophic factors. Therefore, we tested t...

journal_title：Neurochemical research

authors： Albrecht PJ,Enterline JC,Cromer J,Levison SW

更新日期：2007-02-01 00:00:00

abstract：:The activation of caspase-3 is considered to be a reliable marker for apoptotic cell death, and a 120-kDa fragment of αII-spectrin is generated by caspase-3 mediated cleavage of this structural protein. In the present study, we compared cleaved αII-spectrin (120-kDa) and cleaved caspase-3-immunoreactive cells and thei...

journal_title：Neurochemical research

authors： Hwang IK,Ahn JH,Yoo DY,Lee CH,Yoo KY,Choi JH,Moon SM,Shin HC,Won MH

更新日期：2012-03-01 00:00:00

abstract：:Reserpine evokes transsynaptic impulse activity by depleting catecholaminergic neurotransmitters in the rat brain. Previous studies suggest a relationship between catecholaminergic activity and calmodulin concentration. In this report we employ Northern blot analysis to examine the effect of a single subcutaneous inje...

journal_title：Neurochemical research

authors： Ni B,Brown IR

更新日期：1993-02-01 00:00:00

abstract：:Due to the biological importance of sodium and its relative scarcity within many natural environments, 'salt appetite' has evolved whereby dietary salt is highly sought after and palatable when tasted. In addition to peripheral responses, salt depletion is detected within the brain via circumventricular organs and 11β...

journal_title：Neurochemical research

authors： Smith CM,Lawrence AJ

更新日期：2018-01-01 00:00:00

abstract：:The Wistar-Kyoto (WKY) rat strain has been described as an animal model of depressive behavior that consumes significantly greater amounts of alcohol compared to the Wistar (WIS) rat strain. Since the mesolimbic dopamine (DA) type-2 (D2) receptors mediate reward-related behaviors, the present study measured the bindin...

journal_title：Neurochemical research

authors： Morganstern I,Tejani-Butt S

更新日期：2010-11-01 00:00:00

abstract：:Release of endogenous dopamine (DA) and gamma-aminobutyric acid (GABA) from superfused rat caudate synaptosomes was monitored with liquid chromatography with electrochemical detection. Dopamine was analyzed by oxidative detection following alumina extraction while GABA was analyzed with reductive detection following p...

journal_title：Neurochemical research

authors： Caudill WL,Bigelow JC,Wightman RM

更新日期：1985-03-01 00:00:00

abstract：:An analytical method for the determination of saturated very long chain (VLC) fatty acids in the serum has been devised. Free fatty acids obtained after hydrolysis of total lipid extracts were converted into p-bromophenacyl esters. The derivatives were purified in two sequential steps by clean-up on C18 reversed-phase...

journal_title：Neurochemical research

authors： Alberghina M,Fiumara A,Pavone L,Giuffrida AM

更新日期：1984-12-01 00:00:00

abstract：:Most studies of Alzheimer's disease (AD) have focused on a single precipitating alteration as the etiological event rather than global changes closely linked to aging. Recent evidence suggests that the most significant of these global changes are metabolic. Here we present data indicating that metabolic rate, nutritio...

journal_title：Neurochemical research

authors： Perry G,Nunomura A,Raina AK,Aliev G,Siedlak SL,Harris PL,Casadesus G,Petersen RB,Bligh-Glover W,Balraj E,Petot GJ,Smith MA

更新日期：2003-10-01 00:00:00

abstract：:We analyzed two disease model groups with rats infected by Japanese encephalitis virus (JEV), a 90-day group and a 180-day group after JEV infection. The time measured by the modified pole test showed that motor activities in these two groups were slower than those of age-matched control groups. Striatal dopamine (DA)...

journal_title：Neurochemical research

authors： Hamaue N,Ogata A,Terado M,Ohno K,Kikuchi S,Sasaki H,Tashiro K,Hirafuji M,Minami M

更新日期：2006-12-01 00:00:00

abstract：:Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS) and exerts its actions via a number of ionotropic glutamate receptors/channels and metabotropic glutamate (mGlu) receptors. In addition to being expressed in neurons, glutamate receptors are expressed in different types of...

journal_title：Neurochemical research

authors： D'Antoni S,Berretta A,Bonaccorso CM,Bruno V,Aronica E,Nicoletti F,Catania MV

更新日期：2008-12-01 00:00:00

abstract：:The binding of [3H]ethylketocyclazocine ([3H]EKC) under the suppression of mu and delta sites in the brain of EL mice (seizure-susceptible) was examined to determine the relationship between seizures and the dynorphinergic system. The density of kappa-opioid receptors in the cerebrum of adult EL mice during interictal...

journal_title：Neurochemical research

authors： Kai T,Onishi H,Koide S,Katayama M,Yamagami S

更新日期：1998-02-01 00:00:00

abstract：:The antibodies against omega-conotoxin GVIA (omega-CTX GVIA; N-type voltage-dependent calcium channel [VDCC] blocker) and B1Nt (N-terminal segment [residues 1-13] of BI alpha1 subunits of VDCCs) were prepared, and the selectivity for each antigen omega-CTX GVIA and B1Nt was investigated. For the antigen selectivity of...

journal_title：Neurochemical research

authors： Ichida S,Abe J,Sugimoto W,Uematsu M,Komoike K,Imoto K,Mori M,Wada T,Minami T,Kakutani K

更新日期：2003-06-01 00:00:00

abstract：:Metal ions are often used to block calcium channels in various tissues, including synaptosomes. In the present study, Fura-2 was used to determine the effectiveness of various metal ions as calcium channel blockers in rat brain synaptosomes in vitro. In buffer solutions, La3+ and Cd2+ increased the Fura-2 fluorescence...

journal_title：Neurochemical research

authors： Sun YD,Benishin CG

更新日期：1989-11-01 00:00:00

abstract：:The endogenous sialidase (N-acetylneuraminidase) activity of membranes prepared from goldfish retina and optic tectum displays characteristics similar to those reported for neural plasma membrane sialidases of other organisms. Endogenous membrane sialidase activity was found to be optimal at ph 4.0, and maximal releas...

journal_title：Neurochemical research

authors： Leskawa KC,Agranoff BW

更新日期：1983-01-01 00:00:00

abstract：:The release of the inhibitory neurotransmitter GABA is generally enhanced under potentially cell-damaging conditions. The properties and regulation of preloaded [3H]GABA release from mouse hippocampal slices were now studied in free radical-containing medium in a superfusion system. Free radical production was induced...

journal_title：Neurochemical research

authors： Saransaari P,Oja SS

更新日期：2008-03-01 00:00:00

abstract：:Autoantibodies to three eukaryotic 60S ribosomal phosphoproteins P0, P1 and P2 have been found in the sera of 10-20% of patients with systemic lupus erythematosus (SLE). These antibodies inhibit protein synthesis in vitro and when microinjected into cultured human fibroblasts. The three proteins share a common epitope...

journal_title：Neurochemical research

authors： Elkon K,Weissbach H,Brot N

更新日期：1990-04-01 00:00:00

abstract：:We propose the following scheme for cerebral uptake and overall metabolism of glucose in vivo: that brain selects from two pools of glucose anomers in arterial blood, that it takes up excess glucose, that glucose enters the brain tissue as glucose-6-phosphate through the actions of mutarotase and hexokinase, that some...

journal_title：Neurochemical research

authors： Sacks W,Cowburn D,Bigler RE,Sacks S,Fleischer A

更新日期：1985-02-01 00:00:00

abstract：:In this study, we investigated if subunit displacement and/or alterations in proteasome biosynthesis are responsible for the changes in the levels of constitutive proteasomes (c-20S), immunoproteasomes (i-20S) and the activators PA28 and PA700 in neurons and astrocytes cultured with a cytokine mixture (IFN-γ/TNF-α/IL-...

journal_title：Neurochemical research

authors： Shanley KL,Hu CL,Bizzozero OA

更新日期：2020-04-01 00:00:00

abstract：:Serotonin uptake and metabolism was studied in ependymal primary cultures. Serotonin uptake was facilitated by two different systems, one of which was the neuronal serotonin transporter SERT, exhibiting a Vmax value of 3.8+/-0.1 pmol x min(-1) x (mg protein)(-1) and an apparent Michaelis-Menten constant of 0.41+/-0.03...

journal_title：Neurochemical research

authors： Verleysdonk S,Hamprecht B,Rapp M,Wellard J

更新日期：2004-09-01 00:00:00

abstract：:Rhesus macaque monkey brain microvessel endothelial cells (BMECs) were isolated and grown in culture in an effort to establish an appropriate primate in vitro model of the endothelial component of the blood-brain barrier. The presence of Factor VIII antigen, alkaline phosphatase, gamma-glutamyl transpeptidase, lactate...

journal_title：Neurochemical research

authors： Shi F,Audus KL

更新日期：1994-04-01 00:00:00

abstract：:Social isolation during early development is one of the most potent stressors that can cause alterations in the processes of brain maturation, leading to behavioral and neurochemical changes that may persist to adulthood. Exposure to palatable diets during development can also affect neural circuits with long-term con...

journal_title：Neurochemical research

authors： Arcego DM,Krolow R,Lampert C,Noschang C,Pettenuzzo LF,Marcolin ML,Toniazzo AP,Dalmaz C

更新日期：2013-09-01 00:00:00

abstract：:Insulin-like growth factor 1 (IGF-1) stimulates α-secretase processing of amyloid precursor protein (APP) and decreases Aβ production. Little is known about the relationship between IGF-1 and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1), the protease essential for the production of β-amyloid peptides (A...

journal_title：Neurochemical research

authors： Zhang H,Gao Y,Dai Z,Meng T,Tu S,Yan Y

更新日期：2011-01-01 00:00:00

abstract：:Ecto-nucleotidases play a pivotal role in terminating the signalling via ATP and in producing adenosine, a neuromodulator in the nervous system. We have now investigated the pattern of adenosine formation with different concentrations of extracellular ATP in rat hippocampal nerve terminals. It was found that adenosine...

journal_title：Neurochemical research

authors： Cunha RA

更新日期：2001-09-01 00:00:00

abstract：:The K-stimulated release of [3H]ACh from rat midbrain slices prelabeled by incubation with [3H]choline was dependent on extracellular Ca. Phenobarbital inhibited the K-stimulated [3H]ACh release and the IC50 was equal to that found for K-stimulated endogenous ACh release. These results support the suggestion that barb...

journal_title：Neurochemical research

authors： Richter JA,Jackson SK

更新日期：1980-07-01 00:00:00