Magnetic resonance imaging contrast enhancement of brain tumors at 3 tesla versus 1.5 tesla.

Abstract:

RATIONALE AND OBJECTIVES:To compare the diagnostic efficacy of a standard dose of MRI contrast agent in the evaluation of primary brain tumors and metastases using a high-field 3 tesla MR unit versus a 1.5 tesla MR unit. METHODS:Sixteen patients with brain tumors were examined at both field strengths using identical axial T1-SE protocols pre- and postcontrast (0.1 mmol/kg gadolinium), and postcontrast coronal 3D GRE with magnetization preparation (MP-RAGE), which was adjusted separately for each field strength. Evaluation of the images was performed quantitatively and, in the case of T1-SE images, also by visual assessment. RESULTS:Tumor-to-brain-contrast after gadolinium administration using statistical evaluation of MP-RAGE scans was significantly higher at 3 tesla (97.5) than at 1.5 tesla (46.3). The same was true for T1-SE sequences (93.0 vs. 72.1). Signal enhancement of the lesions in T1-SE sequences was not significantly different between both field strengths. CONCLUSIONS:Administration of a gadolinium contrast agent produces higher contrast between tumor and normal brain at 3 tesla than at 1.5 tesla.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Nöbauer-Huhmann IM,Ba-Ssalamah A,Mlynarik V,Barth M,Schöggl A,Heimberger K,Matula C,Fog A,Kaider A,Trattnig S

doi

10.1097/00004424-200203000-00003

keywords:

subject

Has Abstract

pub_date

2002-03-01 00:00:00

pages

114-9

issue

3

eissn

0020-9996

issn

1536-0210

journal_volume

37

pub_type

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