Abstract:
:NADP-malic enzyme (NADP-ME) is a widely distributed enzyme that catalyzes the oxidative decarboxylation of L-malate. Photosynthetic NADP-MEs are found in C4 bundle sheath chloroplasts and in the cytosol of CAM plants, while non-photosynthetic NADP-MEs are either plastidic or cytosolic in various plants. We propose a classification of plant NADP-MEs based on their physiological function and localization and we describe recent advances in the characterization of each isoform. Based on the alignment of amino acid sequences of plant NADP-MEs, we identify putative binding sites for the substrates and analyze the phylogenetic origin of each isoform, revealing several features of the molecular evolution of this ubiquitous enzyme.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Drincovich MF,Casati P,Andreo CSdoi
10.1016/s0014-5793(00)02331-0keywords:
subject
Has Abstractpub_date
2001-02-09 00:00:00pages
1-6issue
1-2eissn
0014-5793issn
1873-3468pii
S0014-5793(00)02331-0journal_volume
490pub_type
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