Parietal endoderm cell line from a rat blastocyst.

abstract：OBJECTIVE:Increasing evidence suggests an association between periodontal disease and low birthweight (LBW); however the underlying molecular mechanisms are yet to be fully elucidated. In this study, we performed a microarray analysis to observe the human placental trophoblast-like BeWo cells response to lipopolysaccha...

journal_title：Placenta

authors： Li Y,Shibata Y,Zhang L,Kuboyama N,Abiko Y

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Pre-gravid obesity is associated with increased morbidity and mortality for both mother and offspring. Recent studies have demonstrated a heightened inflammatory response both systemically and locally within the adipose and placental tissue in women with pre-gravid obesity, which may play a role in mediating...

journal_title：Placenta

authors： Roberts KA,Riley SC,Reynolds RM,Barr S,Evans M,Statham A,Hor K,Jabbour HN,Norman JE,Denison FC

更新日期：2011-03-01 00:00:00

abstract：:Marijuana is one of the most abused drugs among pregnant women leading to maternal and fetal abnormalities. Cannabinoids are the active ingredients of marijuana, which interact with cannabinoid receptors such as CNR1 and CNR2 to activate cellular signaling pathways. Human endometrium and placenta are known to express ...

journal_title：Placenta

authors： Neradugomma NK,Drafton K,O'Day DR,Liao MZ,Han LW,Glass IA,Mao Q

更新日期：2018-06-01 00:00:00

abstract：:Uterine blood flow (UtBF) is a major regulator of transplacental fetal nutrient supply. The aim was to serially measure uterine blood flow from mid to late pregnancy in a paradigm of relatively late onset placental and fetal growth restriction. Singleton bearing adolescent dams was fed high (H) or control (C) nutrient...

journal_title：Placenta

authors： Wallace JM,Milne JS,Matsuzaki M,Aitken RP

更新日期：2008-08-01 00:00:00

abstract：:Pregnant mothers are exposed to a wide variety of foreign chemicals. This exposure is most commonly due to maternal medication, lifestyle factors, such as smoking, drug abuse, and alcohol consumption, or occupational and environmental sources. Foreign compounds may interfere with placental functions at many levels e.g...

journal_title：Placenta

authors： Myllynen P,Pasanen M,Pelkonen O

更新日期：2005-05-01 00:00:00

abstract：INTRODUCTION:miRNAs are small non-coding RNAs important for the regulation of mRNA in many organs including placenta. Adipokines and specifically leptin are known to be dysregulated in preeclampsia, but little is known regarding their regulation by miRNAs during pregnancy. METHODS:We performed high-throughput sequenci...

journal_title：Placenta

authors： Weedon-Fekjær MS,Sheng Y,Sugulle M,Johnsen GM,Herse F,Redman CW,Lyle R,Dechend R,Staff AC

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Prior studies have demonstrated that donor twin survival following treatment of twin-twin transfusion syndrome (TTTS) was highly associated with donor intrauterine growth restriction (IUGR). Here, we hypothesized that donor IUGR may be attributed in part to low placental share. STUDY DESIGN:The study popula...

journal_title：Placenta

authors： Grubbs BH,Benirschke K,Korst LM,Llanes A,Yedigarova L,Chmait RH

更新日期：2011-08-01 00:00:00

abstract：INTRODUCTION:Maternal obesity creates an adverse intrauterine environment, negatively impacts placental respiration, is associated with a higher incidence of pregnancy complications and programs the offspring for disease in adult life in a sexually dimorphic manner. We defined the effect of maternal obesity and fetal s...

journal_title：Placenta

authors： Evans L,Myatt L

更新日期：2017-03-01 00:00:00

abstract：:Several xenobiotic-metabolizing mono-oxygenase activities, in conjunction with the immunohistochemical localization of the respective cytochrome P-450 forms, were investigated in placentae from smoking and non-smoking women. The antibodies used in the immunohistochemical analyses were monoclonal antibodies (MAbs) 1-7-...

journal_title：Placenta

authors： Pasanen M,Stenbäck F,Park SS,Gelboin HV,Pelkonen O

更新日期：1988-05-01 00:00:00

abstract：:Human chorionic gonadotropin (hCG) is the first hormonal message from the placenta to the mother. It is detectable in maternal blood two days after implantation and behaves like an agonist of LH stimulating progesterone secretion by the corpus luteum. hCG has also a role in quiescence of the myometrium and local immun...

journal_title：Placenta

authors： Fournier T,Guibourdenche J,Evain-Brion D

更新日期：2015-04-01 00:00:00

abstract：INTRODUCTION:Transfer of glucose across the human placenta is directly proportional to maternal glucose concentrations even when these are well above the physiological range. This study investigates the relationship between maternal and fetal glucose concentrations and transfer across the placenta. METHODS:Transfer of...

journal_title：Placenta

authors： Day PE,Cleal JK,Lofthouse EM,Hanson MA,Lewis RM

更新日期：2013-10-01 00:00:00

abstract：:The aim of this work was to characterize the uptake of 1-methyl-4-phenylpyridinium (MPP(+)) in the JAR human choriocarcinoma cell line. As JAR cells, as well as the placenta, express the neuronal serotonin transporter (SERT), a comparison between the uptake of (3)H-MPP(+) and (3)H-serotonin ((3)H-5HT) was made. Specif...

journal_title：Placenta

authors： Martel F,Keating E

更新日期：2003-04-01 00:00:00

abstract：:Our objective was to evaluate whether antiphospholipid antibody-containing sera could play a regulatory role in signal transduction induced by gonadotrophin releasing hormone (GnRH) when incubated with normal human trophoblast cells. To test this hypothesis we established an in vitro placental culture system in which ...

journal_title：Placenta

authors： Di Simone N,De Carolis S,Lanzone A,Ronsisvalle E,Giannice R,Caruso A

更新日期：1995-01-01 00:00:00

abstract：INTRODUCTION:Human decidual stromal cells (DSCs) play a key role in maternal-fetal interactions. Precursors of DSCs (preDSCs) localize around vessels in both the endometrium and decidua. Previous studies suggested a relationship between preDSCs and pericytes because these cells share a perivascular location, alpha smoo...

journal_title：Placenta

authors： Muñoz-Fernández R,de la Mata C,Prados A,Perea A,Ruiz-Magaña MJ,Llorca T,Fernández-Rubio P,Blanco O,Abadía-Molina AC,Olivares EG

更新日期：2018-01-01 00:00:00

abstract：:Alphafetoprotein (AFP) is detectable in maternal serum from around six weeks of gestation and is synthesised by the yolk sac and the fetal liver. The role of the placenta in the transport and possible synthesis of AFP is uncertain. The aim of this study was to investigate placental expression of AFP and the AFP recept...

journal_title：Placenta

authors： Newby D,Dalgliesh G,Lyall F,Aitken DA

更新日期：2005-02-01 00:00:00

abstract：:Genomic imprinting, which results in the mono-allelic expression of certain genes in a parent of origin-dependent manner, represents a specialized form of gene regulation which may be vitally important for mammalian development. The mechanisms which underlie imprinting and the molecular nature of the imprint itself re...

journal_title：Placenta

authors： Franklin GC,Adam GI,Ohlsson R

更新日期：1996-01-01 00:00:00

abstract：INTRODUCTION:The aquaporins (AQP1, 3, 8, 9 and 11) are known to be expressed, and involved in the transport of water and small molecules through fetal membranes. To exert these crucial functions, these AQPs have to be finely regulated. All-trans-retinoic acid (atRA) was previously found to regulate some genes in this e...

journal_title：Placenta

authors： Prat C,Bouvier D,Comptour A,Marceau G,Belville C,Clairefond G,Blanc P,Gallot D,Blanchon L,Sapin V

更新日期：2015-08-01 00:00:00

abstract：:It will be apparent from this review that the exact role of IFN on human placental development remains largely undefined. However, there is now sufficient data available on the biological functions of this cytokine in other cellular systems to provide a conceptual framework upon which the influence of IFN on the human...

journal_title：Placenta

authors： Loke YW,King A

更新日期：1990-07-01 00:00:00

abstract：:The human placenta in vivo consumes large amounts of oxygen. After delivery the placenta is exposed to anoxia and under in vitro experimental conditions oxygen consumption is only a fraction of in vivo estimates. In spite of a reduced oxygen supply, structural and functional integrity of the tissue is surprisingly wel...

journal_title：Placenta

authors： Schneider H

更新日期：2000-03-01 00:00:00

abstract：:Autophagy is an inducible catabolic process activated during compromised conditions, such as hypoxia. Neonatal encephalopathy (NE) is a syndrome of disturbed neurological function. No absolute prognostic indicators are available at birth to identify neonates at high risk to develop NE. Immunohistochemical staining wit...

journal_title：Placenta

authors： Avagliano L,Danti L,Doi P,Felis S,Guala M,Locatelli A,Maffeo I,Mecacci F,Plevani C,Simeone S,Bulfamante GP

更新日期：2013-11-01 00:00:00

abstract：:The placental endothelium contributes to regulating transplacental exchange and maintaining the immunological maternofetal barrier. We characterized the endothelial phenotype in human normal term placentae with a panel of antibodies to endothelial antigens using a standardized immunofluorescence method. Placental endo...

journal_title：Placenta

authors： Dye JF,Jablenska R,Donnelly JL,Lawrence L,Leach L,Clark P,Firth JA

更新日期：2001-01-01 00:00:00

abstract：INTRODUCTION:Umbilical artery (UA) hemodynamics reflect blood flow and vascular resistance in the placental circulation. We examined non-invasively the hemodynamic effects of propofol, etomidate, and alphaxalone on the placental circulation of a sheep model by means of UA Doppler ultrasonography. METHODS:Eleven sheep ...

journal_title：Placenta

authors： Domínguez E,Rivera Del Álamo MM,Novellas R,Espada Y,Santos L,García F,Andaluz A,Fresno L

更新日期：2013-09-01 00:00:00

abstract：:The ability of three streptococcal isolates of different pathogenicity to multiply in the tissues of pregnant mice was investigated following intravenous injection. The highly pathogenic isolate multiplied most rapidly whilst the isolate of low pathogenicity showed the least rapid growth within the observation period ...

journal_title：Placenta

authors： Coid CR,Nicholson J

更新日期：1981-07-01 00:00:00

abstract：AIMS:Myocardial structural and functional abnormalities are known to occur in fetuses of mothers with diabetes mellitus (FMDM). The main aim of this investigation was to explore the cardiovascular circulatory patterns in FMDM using a validated lumped computational model of the cardiovascular system. METHODS:This was a...

journal_title：Placenta

authors： Kulkarni A,Garcia-Cañadilla P,Khan A,Lorenzo JM,Beckerman K,Valenzuela-Alcaraz B,Cruz-Lemini M,Gomez O,Gratacos E,Crispi F,Bijnens B

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:Histiotrophe is now recognized as being an important feature of early human pregnancy, providing nutrients and growth factors to the developing embryo. Our aim was to examine the glycan composition of histiotrophe from first trimester decidua and to compare it with secretions present in endometrial glands fr...

journal_title：Placenta

authors： Jones CJ,Aplin JD,Burton GJ

更新日期：2010-07-01 00:00:00

abstract：:The aim of the present study was to evaluate the relationship between the retention of fetal membranes (RFM) and apoptosis of the cells in fetal membranes. The present study investigated mRNA and protein expressions of apoptosis-regulating factors: FAS, cellular FLICE-like inhibiting protein (cFLIP), BAX, BCL2, caspas...

journal_title：Placenta

authors： Kamemori Y,Wakamiya K,Nishimura R,Hosaka Y,Ohtani S,Okuda K

更新日期：2011-01-01 00:00:00

abstract：:The uptake of [3H]choline and its conversion to [3H]acetylcholine were investigated in term human placental tissue in vitro. Although the net uptake of [3H]choline increased throughout a 45 min incubation period, intracellular [3H]choline levels reach a plateau after 2 min. There was a constant increase in [3H]acetylc...

journal_title：Placenta

authors： Leventer SM,Rowell PP

更新日期：1984-05-01 00:00:00

abstract：:Preeclampsia (PE) affects 5-8% of pregnancies and is responsible for 18% of maternal deaths in the US, and for long-term complications in mother and child. PE is an inflammatory state and may influence placental function in a sex-specific manner. We determined if there is a sexual dimorphism in the placental inflammat...

journal_title：Placenta

authors： Muralimanoharan S,Maloyan A,Myatt L

更新日期：2013-12-01 00:00:00

abstract：:Embryo implantation is the group of processes by which the developing blastocyst adheres to, and embeds into, the receptive endometrium. Changes in the expression of molecules on the cell surface have been seen in the conversion of the endometrial surface from a non-receptive to a receptive state. Cell adhesion molecu...

journal_title：Placenta

authors： Zhao M,Chang C,Liu Z,Chen LM,Chen Q

更新日期：2010-12-01 00:00:00

abstract：:Placental villi of early and term human placentae were dissociated with trypsin and mixed cell cultures were established. The different cell types were identified and estimated over a 14-day culture period using antibodies to keratin and vimentin filaments and their capacity to phagocytose yeast. The three main cell t...

journal_title：Placenta

authors： Contractor SF,Routledge A,Sooranna SR

更新日期：1984-01-01 00:00:00