Abstract:
:The human placenta in vivo consumes large amounts of oxygen. After delivery the placenta is exposed to anoxia and under in vitro experimental conditions oxygen consumption is only a fraction of in vivo estimates. In spite of a reduced oxygen supply, structural and functional integrity of the tissue is surprisingly well preserved. Special metabolic adjustments in the sense of 'partial metabolic arrest' may be the explanation for a remarkable survival capacity of placental tissue and reduction of protein synthesis seems to be an important component of metabolic slowdown. The potential significance of this special feature of placental metabolism for the in vivo situation is discussed.
journal_name
Placentajournal_title
Placentaauthors
Schneider Hdoi
10.1053/plac.1999.0512keywords:
subject
Has Abstractpub_date
2000-03-01 00:00:00pages
S38-44eissn
0143-4004issn
1532-3102pii
S014340049990512Xjournal_volume
21 Suppl Apub_type
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