Current topic: interferon and human placental development.

abstract：OBJECTIVES:The epithelium of the human placenta comprises an inner cytotrophoblast (CT) which proliferates and fuses with the outer differentiated syncytiotrophoblast (ST). Turnover has been studied focussing on second and third trimester placentas but with a paucity of data describing the normal first trimester tropho...

journal_title：Placenta

authors： Bose P,Kadyrov M,Goldin R,Hahn S,Backos M,Regan L,Huppertz B

更新日期：2006-08-01 00:00:00

abstract：:Anandamide (AEA) and 2-arachidonoylglycerol (2-AG) were the first endocannabinoids to be characterized, that bind two G protein-coupled receptors, CB1 and CB2. AEA synthesized by multiple pathways, including NAPE-specific phospholipase D (NAPE-PLD) and degraded by the fatty acid amide hydrolase (FAAH). AEA levels are ...

journal_title：Placenta

authors： Trabucco E,Acone G,Marenna A,Pierantoni R,Cacciola G,Chioccarelli T,Mackie K,Fasano S,Colacurci N,Meccariello R,Cobellis G,Cobellis L

更新日期：2009-06-01 00:00:00

abstract：:Endotheliochorial placentas occur in orders from all four major clades of eutherian mammal. Species with this type of placenta include one of the smallest (pygmy shrew) and largest (African elephant) land mammals. The endotheliochorial placenta as a definitive form has an interhemal area consisting of maternal endothe...

journal_title：Placenta

authors： Enders AC,Carter AM

更新日期：2012-05-01 00:00:00

abstract：:Interactions between the highly invasive trophoblasts and the maternal uterine decidual extracellular matrix (ECM) are crucial in the determination of a successful pregnancy. Fibulin-5 (FBLN5) is a member of the fibulin family that alters cell adhesive and invasive properties and is expressed in human villous cytotrop...

journal_title：Placenta

authors： Winship A,Cuman C,Rainczuk K,Dimitriadis E

更新日期：2015-12-01 00:00:00

abstract：:Pregnancy-specific beta 1-glycoprotein (Schwangerschaftsprotein, SP1) is elevated in the amniotic fluid in Meckel's syndrome. In an attempt to clarify this phenomenon, we studied fetal tissues by immunohistochemistry for the distribution of SP1 in normal fetuses and fetuses with Meckel's syndrome. The amount of SP1 wa...

journal_title：Placenta

authors： Heikinheimo M,Jalanko H,Renlund M,Rapola J,Wahlström T

更新日期：1987-07-01 00:00:00

abstract：:Glycogen storage disease type IV (GSD IV) is a rare autosomal recessive disorder caused by glycogen branching enzyme (GBE) deficiency and resulting in the storage of abnormal glycogen (polyglucosan). Prenatal diagnosis is based on biochemical assay of GBE activity or on mutation analysis, but polyglucosan can also be ...

journal_title：Placenta

authors： Konstantinidou AE,Anninos H,Dertinger S,Nonni A,Petersen M,Karadimas C,Havaki S,Marinos E,Akman HO,DiMauro S,Patsouris E

更新日期：2008-04-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to explore serum levels of differentially abundant proteins between women with hypertensive disorders of pregnancy (HDP) and women with normal-term pregnancy, and to explore the contribution of SH3BGRL3 to the pathogenesis of HDP. METHODS:At 6-20 weeks gestation 48 pregnant...

journal_title：Placenta

authors： Jiang M,Lash GE,Zeng S,Liu F,Han M,Long Y,Cai M,Hou H,Ning F,Hu Y,Yang H

更新日期：2020-11-14 00:00:00

abstract：INTRODUCTION:The purpose of this study was to define gross patterns of umbilical cord hypercoiling and determine correlations with histological features in the placenta and/or perinatal outcomes such as stillbirth. METHODS:Gross images of placentas with hypercoiled umbilical cords (>3 coils/10 cm) were assigned a majo...

journal_title：Placenta

authors： Ernst LM,Minturn L,Huang MH,Curry E,Su EJ

更新日期：2013-07-01 00:00:00

abstract：:We have investigated whether maternal peripheral blood from the first trimester of pregnancy is a reliable source of identifiable trophoblast cells. The cells were enriched from 30 ml of venous blood, with multiple antibodies shown previously to enrich trophoblasts and a new cocktail based on known trophoblast surface...

journal_title：Placenta

authors： Schueler PA,Yamanishi DT,Pearson J,Lee Y,Wu X,Hashima S,Madlansacay MR,Cain CA,Collarini EJ,Foltz L,Mahoney W

更新日期：2001-09-01 00:00:00

abstract：:This study examines middle and late gestational placentae from 13 Tayassu tajacu (collared peccary) and 3 Tayassu pecari (white-lipped peccary), which are Artiodactyla belonging to the Family Tayassuidae. The chorionic sac of Tayassu species is diffuse and chorioallantoic. These epitheliochorial placentae show no trop...

journal_title：Placenta

authors： Santos TC,Dantzer V,Jones CJ,Oliveira MF,Miglino MA

更新日期：2006-02-01 00:00:00

abstract：INTRODUCTION:Notch signalling has been shown to control cytotrophoblast (CTB) proliferation, differentiation and motility suggesting that the conserved signalling pathway could be critical for human placental development. Since individual Notch receptors have not been elucidated, we herein investigated expression patte...

journal_title：Placenta

authors： Plessl K,Haider S,Fiala C,Pollheimer J,Knöfler M

更新日期：2015-04-01 00:00:00

abstract：:The mechanism of iron release from the placenta into the fetal circulation is not well understood. Ceruloplasmin, a plasma ferroxidase, has been implicated in iron efflux from a variety of cell types. The hypothesis is that circulating ceruloplasmin facilitates iron efflux by oxidizing the released Fe(II) to Fe(III) f...

journal_title：Placenta

authors： Danzeisen R,Ponnambalam S,Lea RG,Page K,Gambling L,McArdle HJ

更新日期：2000-11-01 00:00:00

abstract：:Changes in placental lipid content in rats at the 15th and 20th days of pregnancy were investigates. It was found that progress of gestation is accompanied by a significant increase in triglycerides per mg placental DNA. Maternal starvation caused additional increase in the placental triglyceride content. By incubatio...

journal_title：Placenta

authors： Diamant YZ,Diamant S,Freinkel N

更新日期：1980-10-01 00:00:00

abstract：:We have previously shown that thioredoxin and thioredoxin reductase were immunohistochemically localized in cytotrophoblasts, decidua and stromal cells in the stem villi of human placenta and that the addition of exogenous thioredoxin and thioredoxin reductase to mitochondrial fractions from human placenta displayed a...

journal_title：Placenta

authors： Ejima K,Koji T,Nanri H,Kashimura M,Ikeda M

更新日期：1999-09-01 00:00:00

abstract：:Oestrogen and progesterone receptors have been implicated in human placental steroidogenesis, but studies developed to measure their concentration in this tissue at term yielded discrepant results. Potential inaccuracy of the binding assays, the technique used in previous studies, might influence the discrepancy. In t...

journal_title：Placenta

authors： Rivera J,Cano A

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVES:To gain insight into the process of labor and the effects of labor on placental gene expression, we performed a microarray analysis to identify the differentially expressed transcripts that may participate in labor onset and progression. METHODS:We compared expression profiles in placentas from 16 women who...

journal_title：Placenta

authors： Lee KJ,Shim SH,Kang KM,Kang JH,Park DY,Kim SH,Farina A,Shim SS,Cha DH

更新日期：2010-08-01 00:00:00

abstract：:Our objective was to evaluate whether antiphospholipid antibody-containing sera could play a regulatory role in signal transduction induced by gonadotrophin releasing hormone (GnRH) when incubated with normal human trophoblast cells. To test this hypothesis we established an in vitro placental culture system in which ...

journal_title：Placenta

authors： Di Simone N,De Carolis S,Lanzone A,Ronsisvalle E,Giannice R,Caruso A

更新日期：1995-01-01 00:00:00

abstract：:The present study was designed to localize some important enzymes, such as adenosine diphospate-degrading enzyme (ADP-degrading enzyme) (plasma membrane enzyme), cytochrome c oxidase (mitochondrial enzyme) and glucose-6-phosphatase (endoplasmic reticulum enzyme), in placentae from patients with idiopathic fetal growth...

journal_title：Placenta

authors： Matsubara S,Sato I

更新日期：2000-03-01 00:00:00

abstract：:Placental function involves multiple different processes which operate at different scales from centimetres to nanometres. Everything that the placenta does from mediating blood flow to gene expression, occurs within a three-dimensional anatomical framework. This review outlines how multiscale three-dimensional imagin...

journal_title：Placenta

authors： Lewis RM,Pearson-Farr JE

更新日期：2020-12-01 00:00:00

abstract：:Throughout its entire lifespan, the placenta is able to produce as well as respond to a variety of inflammatory stimuli. Many signaling molecules and concurrent pathways responsible for the propagation of an inflammatory response have been identified in placental cells. From early developmental stages onward, the secr...

journal_title：Placenta

authors： Hauguel-de Mouzon S,Guerre-Millo M

更新日期：2006-08-01 00:00:00

abstract：:Uterine blood flow (UtBF) is a major regulator of transplacental fetal nutrient supply. The aim was to serially measure uterine blood flow from mid to late pregnancy in a paradigm of relatively late onset placental and fetal growth restriction. Singleton bearing adolescent dams was fed high (H) or control (C) nutrient...

journal_title：Placenta

authors： Wallace JM,Milne JS,Matsuzaki M,Aitken RP

更新日期：2008-08-01 00:00:00

abstract：:Interleukin (IL)-17 is a proinflammatory cytokine with pleiotropic activities including inducing neovascularization and production of proangiogenic molecules. As pregnancy outcome depends on the balance of Th1-like/Th2-like cytokines and an increased blood supply to the fetoplacental unit, the expression of IL-17 mRNA...

journal_title：Placenta

authors： Pongcharoen S,Somran J,Sritippayawan S,Niumsup P,Chanchan P,Butkhamchot P,Tatiwat P,Kunngurn S,Searle RF

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Histiotrophe is now recognized as being an important feature of early human pregnancy, providing nutrients and growth factors to the developing embryo. Our aim was to examine the glycan composition of histiotrophe from first trimester decidua and to compare it with secretions present in endometrial glands fr...

journal_title：Placenta

authors： Jones CJ,Aplin JD,Burton GJ

更新日期：2010-07-01 00:00:00

abstract：:We investigated whether histological evidence of early atherosclerosis was present in the umbilical artery of 21 pregnancies complicated by severe perinatal inflammation, and 21 controls matched for gestational age, sex and birth weight. Severe chorioamnionitis with funisitis was associated with increased numbers of C...

journal_title：Placenta

authors： Rafferty AR,D'Arcy C,Cann L,Pyman J,Rogers P,Davis PG,Nowell C,Burgner D

更新日期：2017-02-01 00:00:00

abstract：:The localization of 5-hydroxytryptamine (5-HT) and its receptors in human placenta was studied under light and electron microscopy using immunohistochemistry and in situ hybridization. The syncytiotrophoblast, cytotrophoblast, stromal cells and decidual cells in human placentae all appeared to be 5-HT immunoreactive. ...

journal_title：Placenta

authors： Huang WQ,Zhang CL,Di XY,Zhang RQ

更新日期：1998-11-01 00:00:00

abstract：INTRODUCTION:Elevated circulating soluble FLT1 (sFLT1) levels seen in preeclampsia may play a role in its development. Aspirin is recommended for prevention of preeclampsia. We hypothesized that aspirin may inhibit the production of sFlt1. METHODS:Placentas from women with and without preeclampsia were collected. Prim...

journal_title：Placenta

authors： Li C,Raikwar NS,Santillan MK,Santillan DA,Thomas CP

更新日期：2015-04-01 00:00:00

abstract：:Apart from during the prepartal period, the main oestrogen produced by the bovine trophoblast is oestrone sulphate (E1S) which does not bind to nuclear oestrogen receptors (ER). High steroid sulphatase (StS) activities previously detected in the maternal part of bovine placentomes (caruncles) suggest the local activat...

journal_title：Placenta

authors： Greven H,Kowalewski MP,Hoffmann B,Geyer J,Rex-Haffner M,Ugele B,Schuler G

更新日期：2007-08-01 00:00:00

abstract：:Decidualization process involves the morphological and functional transformation of endometrial stromal cells into decidual cells. This is a finely regulated process, which involves proliferation and differentiation of stromal cells into decidual cells, which is followed by regression of the decidual tissue, mainly by...

journal_title：Placenta

authors： Fonseca BM,Teixeira NA,Almada M,Taylor AH,Konje JC,Correia-da-Silva G

更新日期：2011-06-01 00:00:00

abstract：:The binding of oestradiol in human placental tissue obtained from spontaneous and caesarean deliveries was investigated. Villous tissue was homogenized and the 800 g 'cytosol' supernatant treated with ammonium sulphate. The precipitate was redissolved and the preparation then equilibrated with [3H]oestradiol. After se...

journal_title：Placenta

authors： Laminski NA,Hammond KD

更新日期：1985-09-01 00:00:00

abstract：:The Ca antigen is expressed by a range of normal tissues, as well as by many malignant neoplasms. The former includes placental villous syncytiotrophoblast where it appears first on syncytial sprouts at 20 weeks gestation, and progressively becomes more intensely and widely expressed on the surface of the trophoblast ...

journal_title：Placenta

authors： Bishop PW,Malam JE,Morris JA,Fox H

更新日期：1990-11-01 00:00:00