Histological changes in the umbilical artery following severe chorioamnionitis and funisitis may be indicative of early atherosclerosis.

abstract：:Physiological data indicate that both a transcellular and a paracellular pathway are available for transfer across the human placenta but the morphological correlate of the latter is uncertain. We measured the permeability of the dually perfused human placental cotyledon to the predominantly cationic protein horseradi...

journal_title：Placenta

authors： Edwards D,Jones CJ,Sibley CP,Nelson DM

更新日期：1993-01-01 00:00:00

abstract：:The human placental syncytiotrophoblast is derived from differentiating cytotrophoblasts and is in contact with maternal blood. This endothelial function positions the trophoblast to regulate maternal-fetal exchange and to influence circulatory dynamics through paracrine interactions in the placenta. Two isoforms of n...

journal_title：Placenta

authors： Lyall F,Jablonka-Shariff A,Johnson RD,Olson LM,Nelson DM

更新日期：1998-05-01 00:00:00

abstract：:Transfection using cationic lipid reagents such as DharmaFECT2 is an efficient tool for introducing siRNA into primary human cytotrophoblast cells. However, we now report a limitation to the use of this method as the concentration of DharamFECT2 needed for effective siRNA delivery causes ligand-independent activation ...

journal_title：Placenta

authors： Desforges M,Westwood M

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:In maternal diabetes the placenta is large with abnormal vascular development and increased villous volume. We used a novel stereological 3D power Doppler ultrasound technique to investigate differences in-vivo in the placental fractional volume of power Doppler signal (FrVol-PD) between women with and witho...

journal_title：Placenta

authors： Jones NW,Deshpande R,Mousa HA,Mansell P,Raine-Fenning N,Bugg G

更新日期：2013-11-01 00:00:00

abstract：:Eighty-one placentae from women with leprosy and 17 placentae from healthy controls were subjected to a detailed macroscopic, light microscopic, ultrastructural, immunopathological, microbiological and biochemical study. The placental morphology and immunohistology were normal, and there was no morphological evidence ...

journal_title：Placenta

authors： Duncan ME,Fox H,Harkness RA,Rees RJ

更新日期：1984-05-01 00:00:00

abstract：:Although secretory phospholipase A2 (PLA2) isozymes have been identified in human gestational tissues, their role in homeostasis and pathophysiology during pregnancy has yet to be clearly established. The aims of this brief commentary are: (1) to review recent data concerning the expression of secretory PLA2 isozymes ...

journal_title：Placenta

authors： Rice GE

更新日期：1998-01-01 00:00:00

abstract：:Human placental villi from both normal and complicated pregnancies were examined by both light and scanning electron microscopy. The findings provide evidence that histological features such as syncytial sprouts, bridges, and a net-like arrangement of villi represent tangential sections of irregularly shaped villi rat...

journal_title：Placenta

authors： Kaufmann P,Luckhardt M,Schweikhart G,Cantle SJ

更新日期：1987-05-01 00:00:00

abstract：:Previous clinical studies have shown the efficacy of a two-stage surgical procedure - the induced membrane (IM) technique - for reconstruction of large bone defects or bone non-union. The first stage involves radical debridement and insertion of a cement spacer into the bone defect. The second stage, performed weeks t...

journal_title：Placenta

authors： Gindraux F,Rondot T,de Billy B,Zwetyenga N,Fricain JC,Pagnon A,Obert L

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:The interaction between trophoblast cells and maternal uterine endothelium is important for placental vascular modelling. Nitric oxide (NO) is a potent vasorelaxant that regulates systemic blood pressure and is reduced in preeclampsia. NO may affect placental cell interaction. OBJECTIVES:This study was to...

journal_title：Placenta

authors： Xu B,Charlton F,Makris A,Hennessy A

更新日期：2014-06-01 00:00:00

abstract：INTRODUCTION:To compare the intertwin umbilical cord coiling in twin-twin transfusion syndrome (TTTS) before fetoscopic laser treatment and to correlate these with Doppler findings in both twins. METHODS:We performed a prospective study using three-dimensional (3D) ultrasound with color Doppler imaging of the umbilica...

journal_title：Placenta

authors： Bamberg C,Diemert A,Glosemeyer P,Tavares de Sousa M,Hecher K

更新日期：2019-01-15 00:00:00

abstract：:The ontogeny of Ia antigen expression on cells within the decidua basalis of the placenta and on decidual cells differentiating in vitro was investigated in the mouse. The results indicate that Ia antigen expression is temporarily restricted and can be detected in short-term cultures of decidual tissue only during the...

journal_title：Placenta

authors： Searle RF,Bell SC,Billington WD

更新日期：1983-04-01 00:00:00

abstract：:To characterize the placental activity for the transport of amino acids, the uptake of L-alanine was investigated by rapid membrane filtration using brush border membrane vesicles separated from the human placenta of early pregnant (12-13 gestational weeks) and late pregnant (37-38 gestational weeks) women. The uptake...

journal_title：Placenta

authors： Iioka H,Hisanaga H,Moriyama IS,Akada S,Shimamoto T,Yamada Y,Ichijo M

更新日期：1992-03-01 00:00:00

abstract：:In order to assess the characteristics of its stromal cells and the distribution of extracellular matrix proteins, we investigated, immunohistochemically and ultrastructurally, term, first and second trimester human umbilical cords. A differential distribution pattern of the various cytoskeletal proteins of stromal ce...

journal_title：Placenta

authors： Nanaev AK,Kohnen G,Milovanov AP,Domogatsky SP,Kaufmann P

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Chronic maternal asthma is associated with reduced growth of the female fetus and normal growth of the male fetus. The mechanisms that control the differential effects of maternal asthma on the fetus have not been fully elucidated but alterations in placental function may play a role. In the current study we...

journal_title：Placenta

authors： Osei-Kumah A,Smith R,Jurisica I,Caniggia I,Clifton VL

更新日期：2011-08-01 00:00:00

abstract：:Mice were inoculated with Theiler's murine encephalomyelitis virus (TMEV) on gestational days 1-3 (pre-implantation) or days 4-5 (peri- or post-implantation) or with control cell lysate (days 1-5). Dams were subsequently sacrificed between days 11-14 of gestation, and placentae and fetuses were harvested. Few placenta...

journal_title：Placenta

authors： Abzug MJ,Tyson RW

更新日期：2000-05-01 00:00:00

abstract：:The dynamics of nickel (Ni) uptake, transfer, retention and clearance in fetuses and late gestational rats were investigated by assessing its distributions in placenta, maternal and fetal organs and tissues during the 24 h period after a single dose of (63)Ni intraperitoneal injection on gestational day 20. Peak (63)N...

journal_title：Placenta

authors： Hou YP,Gu JY,Shao YF,Song YF,Jing YH,Wu WS,Pu S

更新日期：2011-03-01 00:00:00

abstract：:Bovine nuclear transfer pregnancies are characterized by a high incidence of placental abnormalities, notably, increased placentome size and deficiencies in trophoblast cell function and establishment of placental vasculature. Alterations in gene expression during placental growth and development may contribute to the...

journal_title：Placenta

authors： Ravelich SR,Shelling AN,Wells DN,Peterson AJ,Lee RS,Ramachandran A,Keelan JA

更新日期：2006-02-01 00:00:00

abstract：:Stereological methods were used to test whether or not altitudinal, ethnic and sex differences in birthweight in Bolivia are associated with differences in placental morphology. Estimates of the volumes, surface areas, lengths and diameters of villi and of fetal capillaries were obtained by analysing paraffin sections...

journal_title：Placenta

authors： Jackson MR,Mayhew TM,Haas JD

更新日期：1987-09-01 00:00:00

abstract：INTRODUCTION:Visualization of the retroplacental clear space (RPCS) may provide critical insight into the development of abnormally invasive placenta (AIP). In this pre-clinical study, we characterized the appearance of the RPCS on magnetic resonance imaging (MRI) during the second half of gestation using a liposomal g...

journal_title：Placenta

authors： Badachhape AA,Kumar A,Ghaghada KB,Stupin IV,Srivastava M,Devkota L,Starosolski Z,Tanifum EA,George V,Fox KA,Yallampalli C,Annapragada AV

更新日期：2019-02-01 00:00:00

abstract：:The central role of the placenta in the pathogenesis of pre-eclampsia is undisputed. The evidence that maternal syndrome of pre-eclampsia is caused by a maternal systemic inflammatory response (MSIR) is reviewed. The polymorphic nature of the inflammatory network explains the diversity of the varied signs of this cond...

journal_title：Placenta

authors： Redman CW,Sargent IL

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION/OBJECTIVES:Recent studies suggest redness (color) discordance of the placental basal plate may be a marker for twin anemia-polycythemia sequence (TAPS), a recently described complication of diamniotic-monochorionic twinning characterized by marked intertwin hemoglobin (Hb) discordance in the absence of oli...

journal_title：Placenta

authors： De Paepe ME,Gündoğan F,Mao Q,Chu S,Shapiro S

更新日期：2017-12-01 00:00:00

abstract：:As pregnancy progresses the placental syncytiotrophoblast increasingly assumes control of maternal glucose homeostasis through the release and counter-balancing effects of placental lactogen (PL) and placental variant growth hormone (GH-V). While local actions of these hormones on placental growth and function are lik...

journal_title：Placenta

authors： Hill DJ

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:To elucidate whether trophoblast expansion and invasion are modulated by androgen signaling in an in vitro co-culture model system with decidualizing endometrial stromal cells (ESCs). METHODS:We employed an in vitro co-culture model of early embryo implantation, consisting of human ESCs (EtsT499 cells) an...

journal_title：Placenta

authors： Wongwananuruk T,Sato T,Kajihara T,Matsumoto S,Akita M,Tamura K,Brosens JJ,Ishihara O

更新日期：2016-11-01 00:00:00

abstract：:Autophagy is an inducible catabolic process activated during compromised conditions, such as hypoxia. Neonatal encephalopathy (NE) is a syndrome of disturbed neurological function. No absolute prognostic indicators are available at birth to identify neonates at high risk to develop NE. Immunohistochemical staining wit...

journal_title：Placenta

authors： Avagliano L,Danti L,Doi P,Felis S,Guala M,Locatelli A,Maffeo I,Mecacci F,Plevani C,Simeone S,Bulfamante GP

更新日期：2013-11-01 00:00:00

abstract：:Changes in placental lipid content in rats at the 15th and 20th days of pregnancy were investigates. It was found that progress of gestation is accompanied by a significant increase in triglycerides per mg placental DNA. Maternal starvation caused additional increase in the placental triglyceride content. By incubatio...

journal_title：Placenta

authors： Diamant YZ,Diamant S,Freinkel N

更新日期：1980-10-01 00:00:00

abstract：:Workshops are an important part of the IFPA annual meeting. At the IFPA meeting 2008 diverse topics were discussed in 12 themed workshops. Topics covered included: immunology of placentation; galectins and trophoblast invasion; signaling in implantation and invasion; markers to identify trophoblast subpopulations; pla...

journal_title：Placenta

authors： Lash GE,Ansari T,Bischof P,Burton GJ,Chamley L,Crocker I,Dantzer V,Desoye G,Drewlo S,Fazleabas A,Jansson T,Keating S,Kliman HJ,Lang I,Mayhew T,Meiri H,Miller RK,Nelson DM,Pfarrer C,Roberts C,Sammar M,Sharma S,

更新日期：2009-03-01 00:00:00

abstract：:The permeability of the rat placenta at 21 days' gestation (term is 23 days) has been measured with fetuses intact in situ and by perfusion of the fetal circulation. Intact measurements were made by removal of fetuses at known time intervals after injection of radioisotopes to the anaesthetized mother and measurement ...

journal_title：Placenta

authors： Robinson NR,Atkinson DE,Jones CJ,Sibley CP

更新日期：1988-07-01 00:00:00

abstract：:In the present study the possible role of decidual cells in the pregnancy-associated increased sensitivity of glomerular ecto-ADP-ase to endotoxin was investigated. Early (day 5) pregnant (E-Pr; n = 10), pseudopregnant (E-PSP; n = 10), (day 5), pseudopregnant rats with a decidualized uterus (E-DEC; n - 10), as well as...

journal_title：Placenta

authors： Faas MM,Schuiling GA,Baller JF,Valkhof N,Bakker WW

更新日期：1996-03-01 00:00:00

abstract：:Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialised topics. At IFPA meeting 2013 there were twelve themed workshops, three of which are summarized in this report. These workshops related to various aspects of placental biology but collectively covered areas of placent...

journal_title：Placenta

authors： Abumaree MH,Brownbill P,Burton G,Castillo C,Chamley L,Croy BA,Drewlo S,Dunk C,Girard S,Hansson S,Jones S,Jurisicova A,Lewis R,Letarte M,Parast M,Pehrson C,Rappolee D,Schneider H,Tannetta D,Varmuza S,Wadsack C,Wa

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:miRNAs are small non-coding RNAs important for the regulation of mRNA in many organs including placenta. Adipokines and specifically leptin are known to be dysregulated in preeclampsia, but little is known regarding their regulation by miRNAs during pregnancy. METHODS:We performed high-throughput sequenci...

journal_title：Placenta

authors： Weedon-Fekjær MS,Sheng Y,Sugulle M,Johnsen GM,Herse F,Redman CW,Lyle R,Dechend R,Staff AC

更新日期：2014-09-01 00:00:00