Abstract：
:To investigate the possible role of adrenaline in the response of interleukin (IL)-6 and IL-1 receptor antagonists (ra) to extreme physiological conditions such as trauma and exercise, we examined the concentrations in the plasma of these cytokines during an adrenaline infusion. Given the fact that HIV infected patients have elevated levels of IL-6 in plasma, 12 HIV seropositive subjects and 6 HIV seronegative control subjects received a 1-h adrenaline infusion. Baseline concentrations of IL-6 and IL-1ra were higher in the HIV patients compared with the controls (P<0.05 and P<0.01, respectively), being most pronounced in the untreated subgroup of HIV infected patients (n = 6). The plasma concentration of adrenaline had increased 24-fold after 15 min of adrenaline infusion. The plasma concentration of IL-6 had increased by two- to threefold after 45 min of adrenaline infusion (P<0.01) and was still elevated 1 h after the infusion had ended (P<0.001 and P<0.05 in controls and HIV infected patients, respectively). The plasma concentration of IL-1ra had increased two- to threefold 1 h after ceasing the adrenaline infusion (P<0.05 and P<0.01 in controls and HIV infected patients, respectively). The relative increase in the cytokine levels was similar in controls and HIV infected patients. Thus, HIV infection did not influence the effect of adrenaline on IL-6 and IL-1ra. The present study supports the existence of a relationship between the plasma concentration of adrenaline and IL-6. It is possible that an increased adrenaline concentration in plasma induces a continued de novo synthesis of IL-6, thereby increasing plasma IL-6 in a time-dose dependent manner.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Søndergaard SR,Ostrowski K,Ullum H,Pedersen BKdoi
10.1007/s004210000257keywords:
subject
Has Abstractpub_date
2000-09-01 00:00:00pages
95-8issue
1eissn
1439-6319issn
1439-6327journal_volume
83pub_type
杂志文章abstract：:The fatality of deep hypothermia in non-hibernating mammals follows the cessation of respiration and heart beat, and a massive influx of calcium (Ca(++)) into cells. This review presents evidence relating to restoration of key physiological functions during hypothermia in several animal preparations. For example, in a...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-008-0875-7
更新日期：2009-01-01 00:00:00
abstract：:The purpose of this study was to determine the effects of 8 weeks of norsteroid supplementation on body composition and athletic performance in previously weight-trained males. Subjects were weight and percent body fat matched and randomly assigned to receive either 100 mg of 19-nor-4-androstene-3,17-dione (N-dione) a...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s004210100395
更新日期：2001-05-01 00:00:00
abstract：:Cooling of a muscle has a detrimental effect on its force, power and contraction velocity, but may improve force control during precision movements by reducing physiological tremor. We investigated if the contractile characteristics of the first dorsal interosseus muscle (FDI) were linked to voluntary force control in...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-003-0938-8
更新日期：2004-01-01 00:00:00
abstract：PURPOSE:The aim of this study was to examine the influence of age on cycling efficiency and sprint power output in well-trained endurance masters athletes. METHODS:The investigation was conducted on 60 healthy well-trained triathletes separated into six separate groups (n = 10) depending on age: 20-29 years old; 30-39...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-014-2977-8
更新日期：2014-12-01 00:00:00
abstract：PURPOSE:Voluntary breath-holding (BH) elicits several hemodynamic changes, but little is known about maximal static immersed-body BH. We hypothesized that the diving reflex would be strengthened with body immersion and would spare more oxygen than maximal dry static BH, resulting in a longer BH duration. METHODS:Eleve...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-013-2690-z
更新日期：2013-10-01 00:00:00
abstract：:An objective of a warm-up prior to an athletic event is to optimize performance. Warm-ups are typically composed of a submaximal aerobic activity, stretching and a sport-specific activity. The stretching portion traditionally incorporated static stretching. However, there are a myriad of studies demonstrating static s...
journal_title：European journal of applied physiology
pub_type： 杂志文章,评审
doi：10.1007/s00421-011-1879-2
更新日期：2011-11-01 00:00:00
abstract：:This study examined the relation between femoral artery hyperemic responses to leg exercise and microvascular oxygen extraction in nine young [(mean +/- S.E.M) Y: 25 +/- 1 years] and 13 older (O: 67 +/- 1 years) healthy women. Femoral artery blood flow (FBF; Doppler ultrasound), mean arterial pressure (MAP), and femor...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-008-0711-0
更新日期：2008-06-01 00:00:00
abstract：:Physical inactivity in response to a spinal cord injury (SCI) represents a potent stimulus for conduit artery remodelling. Changes in conduit artery characteristics may be induced by the local effects of denervation (and consequent extreme inactivity below the level of the lesion), and also by systemic adaptations due...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-012-2400-2
更新日期：2012-12-01 00:00:00
abstract：:This study examined the influence of prior endurance exercise on hormonal responses to subsequent resistance exercise. Ten males exercised on a cycle ergometer at 50% of maximal oxygen uptake for 60 min and subsequently completed a resistance exercise (bench and leg press, four sets at ten repetitions maximum with an ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-004-1296-x
更新日期：2005-06-01 00:00:00
abstract：:The objective of this study was to evaluate the viability of using a single test in which cardiorespiratory variables are measured, to establish training guidelines in running and/or cycling training activities. Six triathletes (two females and four males), six runners (two females and four males) and six males cyclis...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s004210050033
更新日期：2000-02-01 00:00:00
abstract：:The present study examined the effect of hyperbaric oxygen (HBO) on the formation of 2,3-dihydroxybenzoic acid (2,3-DHBA) and 2,5-dihydroxybenzoic acid (2,5-DHBA), the products of salicylate trapping of hydroxyl free radicals, and glutamate release in the striatum during acute ischemia and reperfusion. Non-HBO rats (n...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-009-1229-9
更新日期：2010-02-01 00:00:00
abstract：:There is a disparity in the information about the heritability of the response of muscle anaerobic metabolism to exercise and the use of explosive power, as well as a lack of information concerning the genetic determinants of this form of work, as measured using different specific physical tests. We applied a battery ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s004210100522
更新日期：2002-01-01 00:00:00
abstract：:Good balance, an important ability in controlling body movement, declines with age. Also, balance appears to decrease when visual input is restricted, while this has been poorly investigated among visually impaired very old adults. The objective of this study is thus to explore whether the balance control of the very ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-011-2139-1
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:Hyperpnea training has been used as a method for both improving exercise performance in healthy persons and improving ventilatory capacity in patients with pulmonary disease. However, voluntary hyperpnea causes acute declines in pulmonary function, but the effects of repeated days of hyperpnea on airway functio...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-020-04302-y
更新日期：2020-03-01 00:00:00
abstract：:A plateau in oxygen consumption (VO(2)) has long been considered the criterion for maximal effort during an incremental exercise test. But, surprisingly, the termination of a maximum exercise test often occurs in the absence of a VO(2) plateau. To explain this inconsistency, some have proposed that an oxygen limitatio...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-003-0845-z
更新日期：2003-08-01 00:00:00
abstract：PURPOSE:Alterations in immunological homeostasis induced by acute exercise have been frequently reported. In view of the growing amount of repetitive exercise stimuli in competitive sports, quick recovery plays a superior role. Therefore, we examined whether aqua cycling affects cellular immunological recovery. METHOD...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-019-04127-4
更新日期：2019-06-01 00:00:00
abstract：:The purpose of this study was to determine for the first time by repeated non-invasive 13C-NMR spectrometry whether blood lactate concentration affects glycogen reduction in non-exercising muscle during prolonged (6 h) physical exercise in healthy adult males. Such an effect would indirectly show that glycogenolysis i...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00421-004-1109-2
更新日期：2004-08-01 00:00:00
abstract：:This study is aimed to evaluate whether circulating adiponectin concentration is associated with physical activity (PA) level in healthy older females. To date, daily PA in older adults (> or = 65 years) has primarily relied on self-report. This study used accelerometry, which objectively measured minute-by-minute mov...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-010-1423-9
更新日期：2010-07-01 00:00:00
abstract：:A routine method to determine total haemoglobin mass (tHb) in clinical practice and sports medicine is non-existent. Radioactive tracers or other dilution procedures like the common CO-rebreathing method (Proc(com)) are impractical, the latter in particular because of the relatively long time of respiration. According...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-005-0050-3
更新日期：2005-12-01 00:00:00
abstract：:The aim of the study was to evaluate the influence of chronic hypobaric hypoxia [43 days at 5050 m above sea level, a.s.l.] on the electrical and mechanical activities of the elbow flexor and knee extensor muscles during sustained maximal isometric contractions. Seven subjects participated in this study. The maximal v...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-003-0922-3
更新日期：2003-10-01 00:00:00
abstract：:This study was performed to examine the effect of diurnal normobaric hypoxia on hematological parameters. Eleven healthy male volunteers were randomly selected to be in either the hypoxic group (n=6) or the control group (n=5). The hypoxic group was exposed to 8 h of normobaric hypoxia in hypoxic tent systems that eli...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-005-0125-1
更新日期：2006-04-01 00:00:00
abstract：:Ten male and ten female young adults trained the knee extensors of one leg eccentrically and those of the other concentrically for 6 weeks, using a gymnasium leg-extension machine. Before and after training, both legs of each subject were tested isometrically for maximum voluntary knee-extensor force, and in both ecce...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s004210000221
更新日期：2000-08-01 00:00:00
abstract：:The purpose of this study was to investigate the effects of unilateral muscle fatigue induced on the hip flexors/extensors or the ankle plantar/dorsiflexors on unipedal postural stability under different visual conditions. Twenty-four healthy young women completed 2 testing sessions 1 week apart with a randomized orde...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-012-2330-z
更新日期：2012-10-01 00:00:00
abstract：PURPOSE:The Na+, K+-ATPase (NKA) is important in regulating trans-membrane ion gradients, cellular excitability and muscle function. We investigated the effects of resistance training in healthy young adults on the adaptability of NKA content and of the specific α and β isoforms in human skeletal muscle. METHODS:Twent...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-020-04408-3
更新日期：2020-08-01 00:00:00
abstract：:Cold-induced vasodilatation (CIVD) is proposed to be a protective response to prevent cold injuries in the extremities during cold exposure, but the laboratory-based trainability of CIVD responses in the hand remains equivocal. Therefore, we investigated the thermal response across the fingers with repeated local cold...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-008-0727-5
更新日期：2008-09-01 00:00:00
abstract：:Trends in industry are leaning toward stereotyped jobs with low workloads. Physical variation is an intervention to reduce fatigue and potentially musculoskeletal disorders in such jobs. Controlled laboratory studies have provided some insight into the effectiveness of physical variation, but very few have been devote...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-012-2375-z
更新日期：2012-11-01 00:00:00
abstract：:In a placebo-controlled study, the effects of intermittent hypoxic exposures (IHE) or a placebo control for 10 days, were examined on the extent of exercise-induced hypoxemia (EIH), cerebral and muscle oxygenation (near-infrared spectroscopy) and VO(2peak). Eight athletes who had previously displayed EIH (fall in satu...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-007-0616-3
更新日期：2008-09-01 00:00:00
abstract：:The aim of the present study was to determine whether glutamine ingestion, which has been shown to enhance the exercise-induced increase in the tricarboxylic acid intermediate (TCAi) pool size, resulted in augmentation of the rate of increase in oxidative metabolism at the onset of exercise. In addition, the potential...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-006-0324-4
更新日期：2007-01-01 00:00:00
abstract：:Androgenic steroids administered in doses at pharmacological levels to sedentary animals have been shown to result in a reduced beta-adrenoceptor-mediated increase in systolic cardiac performance when assessed in vivo. Whether the attenuated adrenergic response occurs as a consequence of alterations in either cardiac ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s004210050048
更新日期：2000-03-01 00:00:00
abstract：PURPOSE:In theory, a slow oxygen uptake ([Formula: see text]) kinetics leads to a greater accumulation of anaerobic by-products, which can, in turn, induce more neuromuscular fatigue. However, the existence of this relationship has never been tested. METHODS:After two sessions to measure peak [Formula: see text], peak...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-017-3585-1
更新日期：2017-05-01 00:00:00
