Abstract：
:In a placebo-controlled study, the effects of intermittent hypoxic exposures (IHE) or a placebo control for 10 days, were examined on the extent of exercise-induced hypoxemia (EIH), cerebral and muscle oxygenation (near-infrared spectroscopy) and VO(2peak). Eight athletes who had previously displayed EIH (fall in saturation of arterial oxygen (SaO(2)) of >4% from rest) during an incremental maximal exercise test, volunteered for the present research. Prior to (baseline), and 2 days following (post) the IHE or placebo, an incremental maximal exercise test was performed whilst SaO(2), heart rate, cerebral and muscle oxygenation and respiratory gas exchange were measured continuously. After IHE, but not placebo, EIH was less pronounced at VO(2peak) (IHE group, SaO(2) at VO(2peak) baseline 91.23 +/- 1.10%, post 94.10 +/- 2.19%; P < 0.01, mean +/- SD). This reduction was reflected in an increased ventilation (NS), a lower end-tidal CO(2) (P < 0.01), and lowered cerebral TOI during heavy exercise (90% VO(2peak): -6.1 +/- 6.0 Delta%, P = 0.04). Conversely, muscle tHb at maximal exercise, was increased (2.4 +/- 1.8 DeltamicroM, P = 0.01, mean +/- 95 CL) following IHE, whilst de-oxygenated Hb at 90% of VO(2peak) was reduced (-0.9 +/- 0.8 DeltamicroM, P = 0.02). These data indicate that exposure to IHE can attenuate the degree of EIH. Despite a potential compromise in cerebral oxygenation, exposure to IHE may induce some positive physiological adaptations at the muscle tissue level. We speculate that the unchanged VO(2peak) following IHE might reflect a balance between these central (cerebral) and peripheral (muscle) adaptations.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Marshall HC,Hamlin MJ,Hellemans J,Murrell C,Beattie N,Hellemans I,Perry T,Burns A,Ainslie PNdoi
10.1007/s00421-007-0616-3subject
Has Abstractpub_date
2008-09-01 00:00:00pages
383-93issue
2eissn
1439-6319issn
1439-6327journal_volume
104pub_type
杂志文章,随机对照试验abstract：:Ten subjects suffering from incomplete spinal cord injuries, clinically diagnosed as walking with Trendelenburg gait, underwent a 2 month therapy program to strengthen their muscles and reduce their gait abnormalities. Therapy involved muscle strengthening and gait training for 2 h a day, 5 days a week in a clinic. Bi...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s004210100466
更新日期：2001-09-01 00:00:00
abstract：PURPOSE:This study investigated whether muscle cooling and its associated effects on skeletal muscle oxidative responses, blood gases, and hormonal concentrations influenced energy metabolism during cycling. METHODS:Twelve healthy participants (Males: seven; Females: five) performed two steady-state exercise sessions ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-020-04407-4
更新日期：2020-08-01 00:00:00
abstract：:To examine sex- and menstrual cycle-related differences in thermoregulatory responses to heat exposure, ten young women and six young men were heated passively by immersing their legs in water heated to 42 degrees C for 60 min (in ambient conditions of 30 degrees C and 45% relative humidity). The women underwent heat ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-004-1303-2
更新日期：2005-06-01 00:00:00
abstract：PURPOSE:A self-paced maximal exercise protocol has demonstrated higher [Formula: see text] values when compared against traditional tests. The aim was to compare physiological responses to this self-paced [Formula: see text] protocol (SPV) in comparison to a traditional ramp [Formula: see text] (RAMP) protocol in young...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-016-3508-6
更新日期：2017-01-01 00:00:00
abstract：:Intense exercise is known to cause temporary impairments in immune function. Few studies, however, have investigated the effects of intense competitive exercise on immunoendocrine variables in elite team sport athletes. The aim of this study was to evaluate the time course of changes in selected immunoendocrine and in...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-009-1200-9
更新日期：2010-01-01 00:00:00
abstract：PURPOSE:To investigate (1) whether maximal stroke volume (SVmax) occurs at submaximal exercise intensities, (2) sex differences in SVmax once fat-free mass (FFM) has been controlled for, and, (3) the contribution of concurrent changes in FFM and SVmax to the sex-specific development of peak oxygen uptake [Formula: see ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-019-04241-3
更新日期：2019-12-01 00:00:00
abstract：:Muscle temperature has a profound effect on the neuromuscular system of young individuals, however, little is known about the effects of altered temperature on the muscles of older individuals. The purpose of this study was to investigate the effect of altered local temperature on maximal torque and electromyography s...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-009-1245-9
更新日期：2010-02-01 00:00:00
abstract：:The aim of this study was to examine the magnitude and the origin of neuromuscular fatigue induced by half-squat static whole-body vibration (WBV) exercise, and to compare it to a non-WBV condition. Nine healthy volunteers completed two fatiguing protocols (WBV and non-WBV, randomly presented) consisting of five 1-min...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-013-2590-2
更新日期：2013-06-01 00:00:00
abstract：:The purpose of this study was to investigate the effects of resistance training on the morphological and functional properties of human lower limb muscles during 20 days of 6 degrees head-down-tilt bed rest. Nine men were randomly assigned to the resistance training group (BR-Tr, n = 5) or the non-training, control gr...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s004210050648
更新日期：2000-05-01 00:00:00
abstract：:Body tilt angle affects the fatigue of human calf muscle at a high contractile force (i.e. 70 %MVC); but the range of forces across which this effect occurs is not known and we sought to determine this in the present study. Fourteen men performed intermittent calf muscle contractions at either 30, 40, 50 and 60 %MVC (...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-006-0308-4
更新日期：2007-01-01 00:00:00
abstract：:The purpose of this study was to determine whether sweat sodium concentration ([Na(+)](sweat)) during exercise in the heat differs between aerobically trained and untrained individuals. On three occasions, ten endurance-trained (Tr) and ten untrained (UTr) subjects (VO2peak = 4.0 ± 0.8 vs. 3.4 ± 0.7 L min(-1), respect...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-011-1911-6
更新日期：2011-11-01 00:00:00
abstract：:One of the possible risks incurred while diving is inert gas narcosis (IGN), yet its mechanism of action remains a matter of controversy. Although providing insights in the basic mechanisms of IGN, research has been primarily limited to animal studies. A human study, in real diving conditions, was needed. Twenty volun...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-012-2391-z
更新日期：2012-12-01 00:00:00
abstract：:Exercise is the example par excellence of the body functioning as a physiological system. Conventionally we think of the O(2) transport process as a major manifestation of that system linking and integrating pulmonary, cardiovascular, hematological and skeletal muscular contributions to the task of getting O(2) from t...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-011-1955-7
更新日期：2012-01-01 00:00:00
abstract：:The purpose of this study was to investigate the effects of unilateral muscle fatigue induced on the hip flexors/extensors or the ankle plantar/dorsiflexors on unipedal postural stability under different visual conditions. Twenty-four healthy young women completed 2 testing sessions 1 week apart with a randomized orde...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-012-2330-z
更新日期：2012-10-01 00:00:00
abstract：:Information on cerebral oxygenation during prolonged driving in healthy humans may help to explain the cause and development of central fatigue and its effects on cortex activities. The objective of this study is to investigate the time course of cerebral oxygenation during a prolonged driving task. Forty healthy male...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-009-1122-6
更新日期：2009-10-01 00:00:00
abstract：PURPOSE:This study aimed to examine the effect of acute blood flow restriction during the late recovery phase between two resistance exercise bouts on muscular endurance and oxygenation. METHODS:Amateur male middle- and long-distance runners performed two bouts of one-leg dynamic plantar flexion exercise to failure wi...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-017-3771-1
更新日期：2018-02-01 00:00:00
abstract：:Isometric maximum voluntary force (MVF) of the adductor pollicis and first dorsal interosseous muscles was measured in 11 pre- and 11 post-menopausal (Pre-M and Post-M) human subjects. The temperature of the hand varied in the range 18°-38°C by water immersion and skin temperature was recorded. MVF at each temperature...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00421-011-2061-6
更新日期：2012-03-01 00:00:00
abstract：PURPOSE:Several studies have shown that the augmentation index (AIx) is negatively correlated with heart rate (HR). This led some authors to claim that the use of HR-lowering drugs may be detrimental in hypertension. The aim of this study was to assess the longitudinal and cross-sectional relationships of HR with AIx a...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-017-3789-4
更新日期：2018-03-01 00:00:00
abstract：PURPOSE:Polyphenolic curcumin is known to have potent anti-inflammatory effects; thus the present study investigated the hypothesis that curcumin ingestion would attenuate muscle damage after eccentric exercise. METHODS:Fourteen untrained young men (24 ± 1 years) performed 50 maximal isokinetic (120°/s) eccentric cont...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-015-3170-4
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:Supra-tolerance head-to-foot directed gravitoinertial load (+Gz) typically induces a sequence of symptoms/signs, including loss of: peripheral vision-central vision-consciousness. The risk of unconsciousness is greater when anti-G-garment failure occurs after prolonged rather than brief exposures, presumably be...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-016-3499-3
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:These studies determined (1) age- and sex-related differences in steadiness of isometric contractions when high cognitive demand was imposed across a range of forces with the elbow flexor muscles (study 1) and; (2) sex differences in steadiness among older adults when low cognitive demand was imposed (study 2)....
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-015-3113-0
更新日期：2015-06-01 00:00:00
abstract：:This study tested the hypothesis that changes in indirect markers of muscle damage following maximal eccentric exercise would be smaller for the knee extensors (KE) and flexors (KF) compared with the elbow flexors (EF) and extensors (EE). A total of 17 sedentary men performed five sets of six maximal isokinetic (90° s...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-010-1648-7
更新日期：2011-02-01 00:00:00
abstract：:The purpose of this study was to describe the force/velocity and power/velocity relationships obtained during squat exercise. The maximal force (F0) was extrapolated from the force/velocity relationship and compared to the isometric force directly measured with the aid of a force platform placed under the subject's fe...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/PL00007956
更新日期：2001-03-01 00:00:00
abstract：:The aim of the present study was to determine whether glutamine ingestion, which has been shown to enhance the exercise-induced increase in the tricarboxylic acid intermediate (TCAi) pool size, resulted in augmentation of the rate of increase in oxidative metabolism at the onset of exercise. In addition, the potential...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-006-0324-4
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:Autonomic assessment might be useful in training management. We planned to assess whether oscillatory metrics of RR variability (such as LFnu) would be more efficient than static indices from low order statistics (RR variance) at discriminating laying rest from stand posture, as an analog of a shift to sympathe...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-016-3337-7
更新日期：2016-04-01 00:00:00
abstract：:In this study, we compared the biomechanical and physiological responses of healthy men and women during bilateral load carriage while they walked on a treadmill at their self-selected velocity. Eleven men mean (SD) maximal oxygen uptake, [VO(2)(max) = 56.0 (7.1) ml x kg(-1) x min(-1)] and 11 women [VO(2)(max) = 44.6 ...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/PL00013800
更新日期：2000-01-01 00:00:00
abstract：PURPOSE:The aim of this study is to describe the effects of speed and gradient during uphill ski mountaineering on energy expenditure, to relate any changes to changes in stride characteristics, and to determine an optimal gradient and speed allowing minimization of energy expenditure. METHODS:11 subjects were tested ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-016-3455-2
更新日期：2016-10-01 00:00:00
abstract：:Although pacing-related research is widely reported, no studies have described the consistency of pacing strategies or their associated energetic contributions. This study aimed to investigate the consistency of pacing and energetic outlay by establishing the typical within and between trial variations during simulate...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00421-010-1818-7
更新日期：2011-08-01 00:00:00
abstract：:Ten male and ten female young adults trained the knee extensors of one leg eccentrically and those of the other concentrically for 6 weeks, using a gymnasium leg-extension machine. Before and after training, both legs of each subject were tested isometrically for maximum voluntary knee-extensor force, and in both ecce...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s004210000221
更新日期：2000-08-01 00:00:00
abstract：:In this study we investigated force loss and recovery after eccentric exercise, and further characterized profound losses in muscle function (n = 192 subjects--98 males, 94 females; population A). Maximal voluntary contractile force (MVC) was assessed before, immediately after, and at 36 and 132 h after eccentric exer...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s004210000346
更新日期：2001-01-01 00:00:00
