Abstract:
:The fatality of deep hypothermia in non-hibernating mammals follows the cessation of respiration and heart beat, and a massive influx of calcium (Ca(++)) into cells. This review presents evidence relating to restoration of key physiological functions during hypothermia in several animal preparations. For example, in anaesthetized hypothermic rats (body temperature 16-17 degrees C), a pharmacologically induced reduction in intracellular [Ca(++)] [via intravenous administration of an ethylenediaminetatraacetate (EDTA) solution (0.15-0.16 mmole)] has been shown to restore cold shivering and respiration after several minutes. Also, activity in an isolated rat heart preparation has been shown to be halted when temperature is reduced in the range 14-12 degrees C. However, decreasing the perfusate [potassium] by a factor of 2-3 relative to normal blood levels restored contractile activity. In conclusion, it is possible to restore the activity of key physiological systems involved in the thermoregulatory responses to sustained hypothermia without the need to rewarm the organism.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Ivanov KPdoi
10.1007/s00421-008-0875-7subject
Has Abstractpub_date
2009-01-01 00:00:00pages
5-12issue
1eissn
1439-6319issn
1439-6327journal_volume
105pub_type
杂志文章abstract:PURPOSE:A self-paced maximal exercise protocol has demonstrated higher [Formula: see text] values when compared against traditional tests. The aim was to compare physiological responses to this self-paced [Formula: see text] protocol (SPV) in comparison to a traditional ramp [Formula: see text] (RAMP) protocol in young...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
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更新日期:2017-01-01 00:00:00
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journal_title:European journal of applied physiology
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journal_title:European journal of applied physiology
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更新日期:2006-01-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1007/s00421-008-0677-y
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journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-013-2790-9
更新日期:2014-03-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
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更新日期:2016-12-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-01-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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journal_title:European journal of applied physiology
pub_type: 杂志文章,评审
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更新日期:2003-10-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-010-1714-1
更新日期:2011-06-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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更新日期:2013-06-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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更新日期:2008-07-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-007-0436-5
更新日期:2007-06-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-017-3700-3
更新日期:2017-10-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
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更新日期:2005-12-01 00:00:00
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journal_title:European journal of applied physiology
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journal_title:European journal of applied physiology
pub_type: 杂志文章,评审
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更新日期:2004-04-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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更新日期:2015-07-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
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更新日期:2019-02-01 00:00:00
abstract::Vibratory stimuli are thought to have the potential to promote neural and/or muscular (re)conditioning. This has been well described for whole-body vibration (WBV), which is commonly used as a training method to improve strength and/or functional abilities. Yet, this technique may present some limitations, especially ...
journal_title:European journal of applied physiology
pub_type: 杂志文章,评审
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更新日期:2017-10-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-002-0655-8
更新日期:2002-08-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-010-1705-2
更新日期:2011-05-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-011-2221-8
更新日期:2012-07-01 00:00:00
abstract::The neuregulin/erbB-signaling axis contributes to the development and growth of multiple mammalian tissues including skeletal muscle. In this study, we sought to characterize the native expression of this system in human skeletal muscle and test the hypothesis that a program of progressive resistance training (PRT) wo...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-005-1333-4
更新日期:2005-07-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-019-04263-x
更新日期:2020-01-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-010-1421-y
更新日期:2010-07-01 00:00:00
abstract::Space flight is a new experience for humans. Humans adapt if not perfectly, rather well to life without gravity. There is a reductive remodeling of the musculo-skeletal system. Protein is lost from muscles and calcium from bones with anti-gravity functions. The observed biochemical and physiological changes reflect th...
journal_title:European journal of applied physiology
pub_type: 杂志文章,评审
doi:10.1007/s00421-012-2548-9
更新日期:2013-09-01 00:00:00