Abstract：
PURPOSE:Walking is a complex locomotor process that involves both spinal cord reflexes and cortical integration of peripheral nerve input. Maintaining an upright body position requires not only neuromuscular activity but also cardiovascular regulation. We postulated that plantar mechanical stimulation might modulate autonomic nervous system activity and, thereby, impact blood pressure adaptation during standing. METHODS:Twelve healthy subjects underwent three randomly ordered 45-min 70°-saddle tilt tests while the plantar surfaces of the feet were stimulated using specially engineered Korvit boots in the following modes: (1) no stimulation, (2) disrupted stimulation, and (3) walking mode. Orthostatic tolerance time was measured for each trial. During testing, we obtained an electrocardiogram and measured blood pressure, skin blood flow, and popliteal vein cross-sectional area. We estimated central hemodynamics, baroreflex sensitivity and heart rate variability. RESULTS:Orthostatic tolerance time was not found to differ significantly between test conditions (37.2 ± 10.4, 40.9 ± 7.6, and 41.8 ± 8.2 min, for no stimulation, disrupted stimulation, and walking mode, respectively). No significant differences between treatment groups were observed for stroke volume or cardiac baroreflex sensitivity, both of which decreased significantly from baseline during tilt testing in all groups. Cardiac sympathetic index and popliteal vein cross-sectional area increased at the end of the tilt period in all groups, without significant differences between treatments. CONCLUSIONS:Plantar mechanical stimulation is insufficient for immediate modulation of cardiac sympathetic and parasympathetic activity under orthostatic stress.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Amirova LE,Navasiolava NM,Bareille MP,Beck A,Tomilovskaya ES,Kozlovzkaya IB,Gauquelin-Koch G,Gharib C,Custaud MAdoi
10.1007/s00421-016-3479-7subject
Has Abstractpub_date
2016-12-01 00:00:00pages
2257-2266issue
11-12eissn
1439-6319issn
1439-6327pii
10.1007/s00421-016-3479-7journal_volume
116pub_type
杂志文章,随机对照试验abstract：:The chronic fatigue syndrome (CFS) has been shown to be associated with orthostatic intolerance and cardiovascular dysregulation. We investigated the cardiovascular responses to combined orthostatic stress and isometric exercise in adolescents with CFS. We included a consecutive sample of 15 adolescents 12-18 years ol...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-007-0634-1
更新日期：2008-04-01 00:00:00
abstract：:Exercise critical power (CP) has been shown to represent the highest sustainable work rate (WR) in patients with chronic obstructive pulmonary disease (COPD). Parameter estimation, however, depends on 4 high-intensity tests performed, on different days, to the limit of tolerance (T(lim)). In order to establish a milde...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-005-0064-x
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:The purpose of this research is to determine the pacing and nutrition strategies which minimize completion time and carbohydrate intake for athletes competing in ultramarathon races. METHODS:We present the formulation of a two-phase optimization model. The first-phase mixed-integer nonlinear program (MINLP) de...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-017-3741-7
更新日期：2017-12-01 00:00:00
abstract：:This study was undertaken to determine the cell adhesion molecule profile of CD4+, CD8hi and CD56+ lymphocytes, which are mobilised to and from the peripheral blood during and after prolonged aerobic exercise. Ten healthy males (21-35 years old) were tested on two occasions, separated by at least 14 days. On the first...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s004210000374
更新日期：2001-04-01 00:00:00
abstract：:The incidence and nature of cardiac arrhythmias during static apnea were studied by monitoring the electrocardiogram (ECG) and oxygen saturation (SaO(2)) of 16 recreational breath-hold divers. All subjects completed a maximal apnea with a mean (+/-SD) breath-hold duration of 281 (+/-73) s without clinical complication...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-008-0945-x
更新日期：2009-03-01 00:00:00
abstract：PURPOSE:Harmful effects of inhaled particulates have been established in epidemiologic studies of ambient air pollution. In particular, heart rate variability responses to high levels of environmental tobacco smoke (ETS), similar to responses observed during direct smoking, have been reported. We sought to determine wh...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-014-2998-3
更新日期：2015-02-01 00:00:00
abstract：:This study presents an original approach to the effect of regular sporting activity on the metabolism of lipids. We have examined the physiological variations of lipoparticles (Lp) AI, Lp B:CIII, Lp B:E, Lp (a) and the principal lipid markers in 21 high-level rugby players and men of the same age group who take part i...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-002-0613-5
更新日期：2002-11-01 00:00:00
abstract：:To determine if there is a sex dimorphism in the skeletal muscle signaling response to sprint exercise, 17 men and ten women performed a 30-s Wingate test. Muscle biopsies were taken before, immediately after the exercise and at 30 and 120 min during the recovery period. Thr(172)-AMPKα, Ser(221)-ACCβ, Thy(705)-STAT3, ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-011-2164-0
更新日期：2012-05-01 00:00:00
abstract：INTRODUCTION:The interchangeability analysis has been recently proposed to objectively assess whether a newly developed measurement tool can substitute the older ones; this analysis assumes that the measures yielded by the compared tools should differ less than a maximum acceptable value. We aimed to assess the interch...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-020-04374-w
更新日期：2020-06-01 00:00:00
abstract：:The unwanted variability in dynamometric measurements limits accurate interpretation of these measurements. Although unpredictable variability in measurements has been identified repeatedly, few studies have investigated strategies for reducing measurement error. This study investigated the effect of preload on variab...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-001-0557-1
更新日期：2002-02-01 00:00:00
abstract：:To compare the cytokine response to exhaustive running in recreationally-active (RA) and endurance-trained (ET) men. Eleven RA men (VO2max 55 ± 7 mL·min(-1)·kg(-1)) and 10 ET men (VO₂max 68 ± 7 mL·min(-1)·kg(-1)) followed a controlled diet and refrained from volitional exercise for 8 days. On the fourth day, participa...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-013-2615-x
更新日期：2013-07-01 00:00:00
abstract：:While there is some controversy whether anaerobic capacity might be improved after altitude training little is known about changes in anaerobic capacity during hypoxic exposure in highly trained athletes. In order to analyze the effects of acute moderate normobaric hypoxia on anaerobic capacity, 18 male competitive tr...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-007-0473-0
更新日期：2007-09-01 00:00:00
abstract：:The sleep-wake state has a profound influence on many, perhaps most, aspects of normal physiology and is strongly implicated in the mediation (or remediation) of impaired health and performance. Many sleep disorders stem from abnormal respiratory anatomy or sleep-induced changes in respiratory control, underscoring th...
journal_title：European journal of applied physiology
pub_type： 杂志文章,评审
doi：10.1007/s00421-002-0610-8
更新日期：2002-07-01 00:00:00
abstract：PURPOSE:The purposes of this study were to evaluate the effect of endurance training on central fatigue development and recovery. METHODS:A control group was compared to a training group, which followed an 8-week endurance-training program, consisting in low-force concentric and isometric contractions. Before (PRE) an...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-015-3123-y
更新日期：2015-07-01 00:00:00
abstract：PURPOSE:In trail running and in uphill races many athletes use poles. However, there are few data about pole walking on steep uphill. The aim of this study was to compare the energy expenditure during uphill walking with (PW) and without (W) poles at different slopes. METHODS:Fourteen mountain running athletes walked ...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-019-04145-2
更新日期：2019-07-01 00:00:00
abstract：:Based on studies using maximal isometric contractions, it is suggested that fatigue may be elicited due to hyperthermia-induced impairments in central neuromuscular activation. We investigated the effects of passive hyperthermia on isokinetic maximal force production. Twenty young healthy males [peak oxygen uptake 52....
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00421-004-1062-0
更新日期：2004-05-01 00:00:00
abstract：PURPOSE:Increased risk of arrhythmic events occurs at certain times during the circadian cycle with the highest risk being in the second and fourth quarter of the day. Exercise improves treatment outcome in individuals with cardiovascular disease. How different exercise protocols affect the circadian rhythm and the ass...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-015-3185-x
更新日期：2015-10-01 00:00:00
abstract：:Sixteen male students exercised for 14 days (1 h/day) in the heat for heat acclimation (HA). During deacclimation (DA) one group exercised in the cold (EXG, n=8) for 60 min/day (morning) and was exposed to the cold for another hour (afternoon) for 14 days. The other group was exposed to the cold (EPG, n=8) for 1 h eac...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-005-0012-9
更新日期：2005-10-01 00:00:00
abstract：:Androgenic steroids administered in doses at pharmacological levels to sedentary animals have been shown to result in a reduced beta-adrenoceptor-mediated increase in systolic cardiac performance when assessed in vivo. Whether the attenuated adrenergic response occurs as a consequence of alterations in either cardiac ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s004210050048
更新日期：2000-03-01 00:00:00
abstract：:It is not known how the mode of exercise, dynamic and static exercises, affects the limb volume. Therefore, the purpose of this study was to investigate hand and wrist volume (HWV) after dynamic and static handgrip exercise. Nine healthy subjects (age 31.8 +/- 7.3 years; height 172.0 +/- 5.7 cm; body mass 66.9 +/- 8.1...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-008-0672-3
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:Many physiological maladaptations persist after overreaching and overtraining resistance exercise (RE). However, no studies have investigated changes in mitogen-activated protein kinases (MAPK) after overtraining in humans, despite their critical role regulating exercise-induced muscular adaptations. The purpos...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-016-3492-x
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:Passive muscle stiffness and muscle architecture at a given joint angle, as well as slack angle of the muscle have been shown to change after an acute bout of stretching. However, it remains unclear whether passive muscle stiffness at a given fascicle length is reduced after stretching. We aimed to elucidate th...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-017-3550-z
更新日期：2017-03-01 00:00:00
abstract：:This study compared the rate of fatigue and lower limb EMG activities during high-intensity constant-load cycling in upright and supine postures. Eleven active males performed seven cycling exercise tests: one upright graded test, four fatigue tests (two upright, two supine) and two EMG tests (one upright, one supine)...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-009-1254-8
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:In cross-country sit-skiing (XCSS), athletes with reduced trunk control predominantly sit with the knees higher than the hips (KH); a position often associated with large spinal flexion. Therefore, to improve spinal curvature a new sledge with frontal trunk support, where knees are lower than hips (KL) was crea...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-017-3596-y
更新日期：2017-06-01 00:00:00
abstract：:The purpose of this study was to determine whether the onset kinetics of muscle oxygenation in localized working muscle (mOxy) was affected by differences in exercise intensity. Five healthy male subjects exercised for 6 min at 125 W, 150 W, and 175 W, and 1 min at 300 W on a cycle ergometer. mOxy was estimated by nea...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00421-004-1045-1
更新日期：2004-05-01 00:00:00
abstract：:This study compared two ankle-mounted pedometers [StepWatch 3 (SW-3(Ankle)) and Activity Monitoring Pod 331 (AMP(Ankle))] and two waist-mounted pedometers [New Lifestyles NL-2000 (NL(Waist)) and Digiwalker SW-701 (SW-701(Waist))] under controlled and free-living conditions. In part I, 20 participants walked on a tread...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-005-0018-3
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:To investigate the effects of lowering core (Tgi) and mean skin temperature (Tsk) concomitantly and independently on self-paced intermittent running in the heat. METHODS:10 males (30.5 ± 5.8 years, 73.2 ± 14.5 kg, 176.9 ± 8.0 cm, 56.2 ± 6.6 ml/kg/min) completed four randomised 46-min self-paced intermittent pr...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-019-04173-y
更新日期：2019-08-01 00:00:00
abstract：:The aim of the present study was to test if the consumption of creatine incorporated in food bars modifies creatine plasma kinetics, erythrocyte retention and loss in urine and in feces when compared with its consumption in the form of an aqueous solution (AS). Seventeen healthy young men ingested 2 g creatine either ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-007-0558-9
更新日期：2008-01-01 00:00:00
abstract：:Sildenafil and epoprostenol are effective therapies in pulmonary arterial hypertension (PAH). Both drugs increase cardiac output, which has been in part attributed to improved right ventricular (RV) contractility. We therefore used tissue Doppler imaging (TDI) to test whether sildenafil and epoprostenol might differen...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-011-2085-y
更新日期：2012-04-01 00:00:00
abstract：:The present study investigated the changes occurring in interstitial metabolite concentrations and blood flow in insulin-resistant human skeletal muscle during the post-exercise recovery period following a single 2-h bout of one-legged exercise. In addition, the effect of microdialysis perfusion with insulin or the in...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-008-0753-3
更新日期：2008-07-01 00:00:00
