Abstract：
:The purpose of this study was to determine the effects of 8 weeks of norsteroid supplementation on body composition and athletic performance in previously weight-trained males. Subjects were weight and percent body fat matched and randomly assigned to receive either 100 mg of 19-nor-4-androstene-3,17-dione (N-dione) and 56 mg of 19-nor-4-androstene-3,17-diol (N-diol; 156 mg total norsteroid per day), or a placebo (a multivitamin). Each subject participated in resistance training 4 days/week for the duration of the study. Body composition was assessed via dual-energy X-ray absorptiometry. Circumference measures were taken of a relaxed and flexed arm (maximum circumference of the arm), waist (level of umbilicus), and thigh (15 cm proximal to the patella). Strength was determined with a one-repetition maximum bench press, while force and power were determined with a dumbbell bench press (60% body weight) on a Stratec Galileo force platform. Profile of mood states scores were evaluated for vigor and fatigue. There were no significant changes in any of the parameters measured. In conclusion, low-dose supplementation with N-dione and N-diol does not appear to alter body composition, exercise performance, or mood states.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Van Gammeren D,Falk D,Antonio Jdoi
10.1007/s004210100395keywords:
subject
Has Abstractpub_date
2001-05-01 00:00:00pages
426-31issue
5eissn
1439-6319issn
1439-6327journal_volume
84pub_type
临床试验,杂志文章,随机对照试验abstract：PURPOSE:This study tested the hypothesis that a novel, audio-visual-directed, home-based exercise training intervention would be effective at improving cardiometabolic health and mental well-being in inactive premenopausal women. METHODS:Twenty-four inactive premenopausal women (39 ± 10 years) were randomly assigned t...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-020-04315-7
更新日期：2020-04-01 00:00:00
abstract：:This study investigated fatigue-induced changes in spring-mass model characteristics during repeated running sprints. Sixteen active subjects performed 12 × 40 m sprints interspersed with 30 s of passive recovery. Vertical and anterior-posterior ground reaction forces were measured at 5-10 m and 30-35 m and used to de...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-010-1638-9
更新日期：2011-01-01 00:00:00
abstract：:Maximal exercise elicits systemic acidosis where venous pH can drop to 6.74 and here we assessed how much lower the intracellular value (pH(i)) might be. The wrist flexor muscles are intensively involved in rowing and (31)P-magnetic resonance spectroscopy allows for calculation of forearm pH(i) and energy metabolites ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-010-1451-5
更新日期：2010-08-01 00:00:00
abstract：PURPOSE:These studies determined (1) age- and sex-related differences in steadiness of isometric contractions when high cognitive demand was imposed across a range of forces with the elbow flexor muscles (study 1) and; (2) sex differences in steadiness among older adults when low cognitive demand was imposed (study 2)....
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-015-3113-0
更新日期：2015-06-01 00:00:00
abstract：:The purpose of this study was to determine whether cross-education, defined as the increase in strength of an untrained limb after training of the contralateral homologous limb, is specific to low and high velocity eccentric training. Twenty-six subjects were randomized into two groups ( n=13 each) that performed unil...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00421-003-0841-3
更新日期：2003-08-01 00:00:00
abstract：:We have previously shown that Achilles tendon length is related to walking economy on the flat, presumably because of increased stretch-shortening cycle elastic energy savings. In addition, greater walking economy in African American (AA) women compared to European American (EA) women is explained by longer Achilles t...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00421-010-1816-9
更新日期：2011-08-01 00:00:00
abstract：:The purpose of this study was to investigate the differences in the viscoelastic properties of human tendon structures (tendon and aponeurosis) in the medial gastrocnemius muscle between men (n=16) and women (n=13). The elongation of the tendon and aponeurosis of the medial gastrocnemius muscle was measured directly b...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00421-002-0744-8
更新日期：2003-02-01 00:00:00
abstract：:The purpose of this study was to describe the force/velocity and power/velocity relationships obtained during squat exercise. The maximal force (F0) was extrapolated from the force/velocity relationship and compared to the isometric force directly measured with the aid of a force platform placed under the subject's fe...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/PL00007956
更新日期：2001-03-01 00:00:00
abstract：:To study the process of O(2) transport to tissue, we investigated how capillary perfusion is controlled in response to changes in tissue O(2) levels in skeletal muscle. Capillary red blood cell (RBC) velocity and perfused capillary recruitment were measured in rabbit tenuissimus muscle at various ambient oxygen tensio...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-005-1315-6
更新日期：2005-06-01 00:00:00
abstract：PURPOSE:To compare the increases in upper- and lower-body muscle strength in premenopausal women performing resistance training (RT) alone or alongside concurrent high-intensity interval training (CT). METHODS:Sixteen women (26-40 years) were randomly assigned into two groups that performed either RT or CT. Both group...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-017-3614-0
更新日期：2017-06-01 00:00:00
abstract：:Intermittent hypoxic exposure with exercise training is based on the assumption that brief exposure to hypoxia is sufficient to induce beneficial muscular adaptations mediated via hypoxia-inducible transcription factors (HIF). We previously demonstrated (Mounier et al. Med Sci Sports Exerc 38:1410-1417, 2006) that leu...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-008-0928-y
更新日期：2009-03-01 00:00:00
abstract：:This study examined standard echocardiographic measures of cardiac size and performance in response to a 3-h firefighting training exercise. Forty experienced male personnel completed a standardized 3 h live firefighting exercise. Before and after the firefighting activities, participants were weighed, height, heart r...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-011-2033-x
更新日期：2012-02-01 00:00:00
abstract：:Evidence indicates that repeated-bouts of eccentric exercise (EE) do not exacerbate the extent of muscle damage indices, as compared to a single-bout. We hypothesized that molecular adaptations, under repeated-bouts of EE, would include suppression of muscle repair inhibitory factors such as myostatin and up-regulatio...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-007-0510-z
更新日期：2007-11-01 00:00:00
abstract：:Single bout whole-body vibration (WBV) exercise has been shown to produce small but significant increases in oxygen consumption (VO(2)). How much more a complete whole-body exercise session (multiple dynamic exercises targeting both upper and lower body muscles) can increase VO(2) is unknown. The purpose of this study...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-011-1984-2
更新日期：2012-02-01 00:00:00
abstract：:In order to test our hypothesis that muscle condition has an effect on the cognition of self-motion and consequently on the ventilatory response during exercise, six healthy subjects performed a moderate incremental exercise test (IET) on a cycle ergometer under two conditions [resistance exercise condition (REC) and ...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-010-1801-3
更新日期：2011-08-01 00:00:00
abstract：:Stoppage of endurance exercise training leads to complete loss of maximal oxygen uptake ([Formula: see text]) gain but not submaximal exercise blood lactate concentrations. However, the detailed mechanisms are still unknown. Thus, we investigated the effects of exercise-training cessation at lactate threshold (LT) int...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00421-011-2036-7
更新日期：2012-03-01 00:00:00
abstract：:This study is aimed to evaluate whether circulating adiponectin concentration is associated with physical activity (PA) level in healthy older females. To date, daily PA in older adults (> or = 65 years) has primarily relied on self-report. This study used accelerometry, which objectively measured minute-by-minute mov...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-010-1423-9
更新日期：2010-07-01 00:00:00
abstract：:According to the literature the steady-state level of phosphocreatine (PCr) has a linear relationship to the workload during muscle exercise intensities below the lactate threshold, whereas this linearity is impaired during exercise intensities above the lactate threshold. The purpose of this study was to investigate ...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00421-004-1233-z
更新日期：2005-01-01 00:00:00
abstract：:Velocity at VO(2 max) (vV(.)O(2 max)) and peak treadmill velocity (PTV) are variables highly predictive of endurance performance. However, how these variables are affected by the menstrual cycle is unknown. The aim of this study was to assess the effect of the menstrual cycle on vV(.)O(2 max) and PTV. Ten, female runn...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-004-1272-5
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:This pilot study investigated differences in lean tissue mass, muscle strength, muscle quality (strength per unit of muscle mass; MQ), and functional performance in healthy younger and older individuals. The most robust predictors of appendicular lean mass (ALM) were then determined in each group. METHODS:Fift...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-019-04107-8
更新日期：2019-05-01 00:00:00
abstract：PURPOSE:Locomotor muscle fatigue impairs exercise performance during time to exhaustion tests. However, its effect on self-regulation of power output (pacing) is unknown. The primary aim of this study was to investigate the effects of locomotor muscle fatigue on pacing and time trial performance. METHODS:Ten healthy r...
journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00421-013-2673-0
更新日期：2013-09-01 00:00:00
abstract：:The purpose of this study was to examine the physiological effects of 3000-m swimming on subsequent 3-h cycling time trial performance in ultraendurance triathletes. Eight highly trained ultraendurance triathletes [mean (SEM) age 34 (2) years, body fat 12.5 (0.8)%, maximum oxygen consumption 63.2 (2.1) ml x kg(-1) x m...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s004210000229
更新日期：2000-09-01 00:00:00
abstract：PURPOSE:Besides mechanical loading of the back, physiological strain is an important risk factor for low-back pain. Recently a passive exoskeleton (SPEXOR) has been developed to reduce loading on the low back. We aimed to assess the effect of this device on metabolic cost of repetitive lifting. To explain potential eff...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-019-04284-6
更新日期：2020-02-01 00:00:00
abstract：:Skin surface cooling has been shown to improve orthostatic tolerance; however, the influence of severe heat stress on cardiovascular and cerebrovascular responses to skin cooling remains unknown. Nine healthy males, resting supine in a water-perfusion suit, were heated to +1.0 and +2.0 degrees C elevation in body core...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-009-1298-9
更新日期：2010-05-01 00:00:00
abstract：:The aim of this study was to examine the effects of low carbohydrate (CHO) availability on heart rate variability (HRV) responses during moderate and severe exercise intensities until exhaustion. Six healthy males (age, 26.5 +/- 6.7 years; body mass, 78.4 +/- 7.7 kg; body fat %, 11.3 +/- 4.5%; V(O)(2)(max) 39.5 +/- 6....
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-009-1329-6
更新日期：2010-04-01 00:00:00
abstract：PURPOSE:Topical application of nonivamide-nicoboxil cream to resting legs has been shown to enhance the level of oxygenated haemoglobin in leg muscles 15 min later. Here, we examined whether such application improves the performance of experienced cyclists in a subsequent 4-km time-trial. METHODS:Nine male cyclists [2...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-016-3357-3
更新日期：2016-05-01 00:00:00
abstract：:An intermittent exposure to artificial hypergravity with physical exercise by a human centrifuge may provide a countermeasure against various physiological problems after space flight. To test the effects of hypergravity with ergometric exercise on dynamic regulation of heart rate during weightlessness, we quantified ...
journal_title：European journal of applied physiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00421-004-1308-x
更新日期：2005-06-01 00:00:00
abstract：:All studies on the oxygen uptake (VO2) slow component have been carried out for the sporting disciplines of cycling or running, but never for swimming. Considering that front crawl swimming is a sport discipline that is fundamentally different from both running and cycling, the aim of this study was to verify whether ...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s004210000348
更新日期：2001-01-01 00:00:00
abstract：:Exercise is the example par excellence of the body functioning as a physiological system. Conventionally we think of the O(2) transport process as a major manifestation of that system linking and integrating pulmonary, cardiovascular, hematological and skeletal muscular contributions to the task of getting O(2) from t...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-011-1955-7
更新日期：2012-01-01 00:00:00
abstract：:The purpose of this study was to assess cardiac function and arteriovenous oxygen difference (a-vO(2) difference) at rest and during exercise in young, normal-weight (n = 20), and obese (n = 12) men and women who were matched for age and fitness level. Participants were assessed for body composition, peak oxygen consu...
journal_title：European journal of applied physiology
pub_type： 杂志文章
doi：10.1007/s00421-010-1554-z
更新日期：2011-06-01 00:00:00
