Aphidicolin inhibits DNA replication in the micronucleus and blocks cytokinesis in Paramecium caudatum.

Abstract:

:Aphidicolin, a selective inhibitor of DNA polymerase, totally blocks DNA replication in the micronucleus but not in the macronucleus of Paramecium caudatum. The ciliates no longer divide and after 4 days the DNA content of the macronucleus has increased by 64%. Concomitantly the cell volume has increased by 53%.

journal_name

Cell Biol Int

authors

Sabaneyeva E,Tao W,Verbelen JP

doi

10.1006/cbir.1999.0482

keywords:

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

859-62

issue

12

eissn

1065-6995

issn

1095-8355

pii

S1065-6995(99)90482-1

journal_volume

23

pub_type

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