Abstract:
:This paper describes a Bayesian method for three-dimensional registration of brain images. A finite element approach is used to obtain a maximum a posteriori estimate of the deformation field at every voxel of a template volume. The priors used by the MAP estimate penalize unlikely deformations and enforce a continuous one-to-one mapping. The deformations are assumed to have some form of symmetry, in that priors describing the probability distribution of the deformations should be identical to those for the inverses (i.e., warping brain A to brain B should not be different probablistically from warping B to A). A gradient descent algorithm is presented for estimating the optimum deformations.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Ashburner J,Andersson JL,Friston KJdoi
10.1002/(sici)1097-0193(200004)9:4<212::aid-hbm3>3keywords:
subject
Has Abstractpub_date
2000-04-01 00:00:00pages
212-25issue
4eissn
1065-9471issn
1097-0193pii
10.1002/(SICI)1097-0193(200004)9:4<212::AID-HBM3>3journal_volume
9pub_type
杂志文章abstract::Variability in human behavior related to sex is supported by neuroimaging studies showing differences in brain activation patterns during cognitive task performance. An emerging field is examining the human connectome, including networks of brain regions that are not only temporally-correlated during different task co...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20968
更新日期:2010-11-01 00:00:00
abstract::Past neuroimaging studies have focused on identifying specialized functional brain systems for processing different components of reading, such as orthography, phonology, and semantics. More recently, a few experiments have been performed to look into the integration and interaction of distributed neural systems for v...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22792
更新日期:2015-07-01 00:00:00
abstract::Parkinsonism has heterogeneous nature, showing distinctive patterns of disease progression and prognosis. We aimed to find clusters of parkinsonism based on 18 F-fluoropropyl-carbomethoxyiodophenylnortropane (FP-CIT) PET as a data-driven approach to evaluate heterogenous dopaminergic neurodegeneration patterns. Two di...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25155
更新日期:2020-11-01 00:00:00
abstract::Successful response selection relies on constantly updating stimulus-response associations. The Theory of Event Coding (TEC) proposes that perception and action are conjointly coded in event files, for which fronto-striatal networks seem to play an important role. However, the exact neurobiochemical mechanism behind e...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25335
更新日期:2021-01-09 00:00:00
abstract::White matter (WM) microstructure, as determined by diffusion tensor imaging (DTI), is increasingly recognized as an important determinant of cognitive function and is also altered in neuropsychiatric disorders. Little is known about genetic and environmental influences on WM microstructure, especially in early childho...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24436
更新日期:2019-03-01 00:00:00
abstract::The dopaminergic system plays a key role in motor function and motor abnormalities have been shown to be a specific feature of psychosis. Due to their dopaminergic action, antipsychotic drugs may be expected to modulate motor function, but the precise effects of these drugs on motor function remain unclear. We carried...
journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
doi:10.1002/hbm.23485
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:To investigate the function-structure relationship of white matter within different stages of Huntington's disease (HD) using diffusion tensor imaging (DTI). EXPERIMENTAL DESIGN:From the TRACK-HD study, an early stage HD group and a premanifest gene carrier group (PMGC) were age-matched to two healthy contr...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21205
更新日期:2012-01-01 00:00:00
abstract::Although imbalanced functional integration has been increasingly reported in major depressive disorder (MDD), there still lacks a general framework to characterize common characteristic and origin shared by the integrative disturbances. Here we examined spatial selectivity, temporal uniqueness, metabolic basis, and th...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23976
更新日期:2018-05-01 00:00:00
abstract::The extent of central nervous system involvement in Kennedy's disease (KD) relative to other motor neuron disease (MND) phenotypes still needs to be clarified. In this study, we investigated cortical and white matter (WM) MRI alterations in 25 patients with KD, compared with 24 healthy subjects, 25 patients with spora...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24583
更新日期:2019-07-01 00:00:00
abstract::Medial temporal lobe (MTL) subregions play integral roles in memory function and are differentially affected in various neurological and psychiatric disorders. The ability to structurally and functionally characterize these subregions may be important to understanding MTL physiology and diagnosing diseases involving t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23887
更新日期:2018-02-01 00:00:00
abstract::The brain seeks to combine related inputs from different senses (e.g., hearing and vision), via multisensory integration. Temporal information can indicate whether stimuli in different senses are related or not. A recent human fMRI study (Noesselt et al. [2007]: J Neurosci 27:11431-11441) used auditory and visual trai...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21278
更新日期:2012-05-01 00:00:00
abstract::Musical expertise is visible both in the morphology and functionality of the brain. Recent research indicates that functional integration between multi-sensory, somato-motor, default-mode (DMN), and salience (SN) networks of the brain differentiates musicians from non-musicians during resting state. Here, we aimed at ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23565
更新日期:2017-06-01 00:00:00
abstract::Previous studies have demonstrated that the right ventrolateral prefrontal cortex (RVLPFC) is crucially involved in downregulating physical and social pain. However, it remains unclear whether the RVLPFC is more specific to either physical or social pain. The present study compares the role of RVLPFC in emotion regula...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24881
更新日期:2020-04-01 00:00:00
abstract::People tend to lie in varying degrees. To advance our understanding of the underlying neural mechanisms of this heterogeneity, we investigated individual differences in self-serving lying. We performed a functional magnetic resonance imaging study in 37 participants and introduced a color-reporting game where lying ab...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24432
更新日期:2019-03-01 00:00:00
abstract::Ten healthy adults encountered pictures of unfamiliar archaic tools and successfully learned either their name, verbal definition of their usage, or both. Neural representation of the newly acquired information was probed with magnetoencephalography in an overt picture-naming task before and after learning, and in two...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20561
更新日期:2009-03-01 00:00:00
abstract::The applicability of functional magnetic resonance imaging (fMRI) in patients with Alzheimer's disease (AD) or schizophrenia is frequently limited by cognitive impairment, which prevents the adequate execution of complex tasks. An experimental design that puts only minor demands on the patients' cognitive ability but ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10071
更新日期:2002-12-01 00:00:00
abstract::Individual differences in general cognitive ability (i.e., intelligence) have been linked to individual variations in the modular organization of functional brain networks. However, these analyses have been limited to static (time-averaged) connectivity, and have not yet addressed whether dynamic changes in the config...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24807
更新日期:2020-02-01 00:00:00
abstract::Voxel-based analyses (VBA) are increasingly being used to detect white matter abnormalities with diffusion tensor imaging (DTI) in different types of pathologies. However, the validity, specificity, and sensitivity of statistical inferences of group differences to a large extent depend on the quality of the spatial no...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20794
更新日期:2009-11-01 00:00:00
abstract::The literature points to a large distributed brain network involved in the estimation of time. Among these regions, the role of the insular cortex is still poorly understood. At the confluence of emotional, interoceptive, and environmental signals, this brain structure has been proposed to underlie awareness of the pa...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24460
更新日期:2019-04-01 00:00:00
abstract::A persistent problem in developing plausible neurophysiological models of perception, cognition, and action is the difficulty of characterizing the interactions between different neural systems. Previous studies have approached this problem by estimating causal influences across brain areas activated during cognitive ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20772
更新日期:2009-06-01 00:00:00
abstract::3,4-Methylenedioxymethamphetamine (MDMA; 'Ecstasy') is a psychostimulant drug producing heightened mood and facilitated social communication. In animal studies, MDMA effects are primarily mediated by serotonin (5-HT), but also by dopamine (DA) and possibly noradrenaline (NA). In humans, however, the neurochemical and ...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/hbm.1049
更新日期:2001-11-01 00:00:00
abstract::To generate imaging biomarkers from disease-specific brain networks, we have implemented a general toolbox to rapidly perform scaled subprofile modeling (SSM) based on principal component analysis (PCA) on brain images of patients and normals. This SSMPCA toolbox can define spatial covariance patterns whose expression...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22295
更新日期:2014-05-01 00:00:00
abstract::Classical delay eyeblink conditioning is likely the most commonly used paradigm to study cerebellar learning. As yet, few studies have focused on extinction and savings of conditioned eyeblink responses (CRs). Saving effects, which are reflected in a reacquisition after extinction that is faster than the initial acqui...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23641
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:Recovery of independent ambulation after stroke is a major goal. However, which rehabilitation regimen best benefits each individual is unknown and decisions are currently made on a subjective basis. Predictors of response to specific therapies would guide the type of therapy most appropriate for each patien...
journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
doi:10.1002/hbm.23059
更新日期:2016-02-01 00:00:00
abstract::In addition to its role in visuospatial navigation and the generation of spatial representations, in recent years, the hippocampus has been proposed to support perceptual processes. This is especially the case where high-resolution details, in the form of fine-grained relationships between features such as angles betw...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24865
更新日期:2020-04-01 00:00:00
abstract::The perspective from where the world is perceived is an important aspect of the bodily self and may break down in neurological conditions such as out-of-body experiences (OBEs). These striking disturbances are characterized by disembodiment, an external perspective and have been observed after temporoparietal damage. ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20764
更新日期:2009-06-01 00:00:00
abstract::Although the brain areas in the default-mode network (DMN) act in a coordinated way during rest, the activity levels in the individual areas of the DMN are highly heterogeneous. The relation between the activity levels and the pattern of causal interaction among the DMN areas remains unknown. In the present fMRI study...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21065
更新日期:2011-01-01 00:00:00
abstract::Auditory steady-state responses (ASSRs) are evoked brain responses to modulated or repetitive acoustic stimuli. Investigating the underlying neural generators of ASSRs is important to gain in-depth insight into the mechanisms of auditory temporal processing. The aim of this study is to reconstruct an extensive range o...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25262
更新日期:2021-02-15 00:00:00
abstract::The nuclei of the human amygdala remain difficult to distinguish in individual subject structural magnetic resonance images. However, interpretation of the amygdala's role in whole brain networks requires accurate localization of functional activity to a particular nucleus or subgroup of nuclei. To address this, high ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23289
更新日期:2016-11-01 00:00:00
abstract::In daily life, we permanently need to adapt our behavior to new task situations, requiring cognitive control. Such adaptive processes are commonly investigated with the task-switching paradigm. Many fMRI studies have interpreted stronger activation for switch than repeat trials in fronto-parietal brain areas as reflec...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21234
更新日期:2012-03-01 00:00:00