Abstract:
:The identification of STING as a key cytoplasmic innate recognition molecule for DNA viruses whose function is lost in a variety of cancers has coincided with the approval of IMLYGIC for metastatic melanoma. This represents the first replication competent viral therapy approved for the treatment of any cancer in the US. The role of STING pathway in the selectivity of HSV has been addressed for the first time in Xia et al (1).
journal_name
Trends Cancerjournal_title
Trends in cancerauthors
Thorne SHdoi
10.1016/j.trecan.2016.01.002subject
Has Abstractpub_date
2016-02-01 00:00:00pages
67-68issue
2eissn
2405-8033issn
2405-8025journal_volume
2pub_type
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