Abstract:
:Tumor heterogeneity is a large conundrum in cancer medicine, making most therapeutic interventions palliative rather than curative. Here we discuss the implications of how molecularly targeted therapies in solid malignancies that promote limited cancer cell death may in fact make tumors more heterogeneous, increase aggressive phenotypes, and thus worsen patient outcomes.
journal_name
Trends Cancerjournal_title
Trends in cancerauthors
Khatib S,Pomyen Y,Dang H,Wang XWdoi
10.1016/j.trecan.2020.01.010subject
Has Abstractpub_date
2020-04-01 00:00:00pages
267-271issue
4eissn
2405-8033issn
2405-8025pii
S2405-8033(20)30026-1journal_volume
6pub_type
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