Abstract：
:Fusobacterium nucleatum is an oral bacterium associated with colorectal cancer (CRC) proliferation, chemoresistance, inflammation, metastasis, and now DNA damage. While controlling F. nucleatum through antibiotics could reduce cancer severity, this article proposes additional strategies to block Fusobacterium-host interactions, as well as treatment of activated host immune and oncogenic signaling pathways in CRC.
journal_name
Trends Cancerjournal_title
Trends in cancerauthors
Slade DJdoi
10.1016/j.trecan.2020.11.006subject
Has Abstractpub_date
2020-12-09 00:00:00eissn
2405-8033issn
2405-8025pii
S2405-8033(20)30307-1pub_type
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