A Molecular Take on Malignant Rhabdoid Tumors.

Abstract:

:The molecular basis for the clinical heterogeneity observed in patients with malignant rhabdoid tumors is unknown. Recently, two reports revealed molecular inter-tumor heterogeneity in teratoid/rhabdoid tumors (ATRTs) and extra-cranial MRTs (ecMRTs) using genomic, transcriptomic and epigenomic profiling. Distinct molecular subgroups were identified and new therapeutic targets were revealed.

journal_name

Trends Cancer

journal_title

Trends in cancer

authors

Tang M,Verhaak RG

doi

10.1016/j.trecan.2016.04.003

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

217-218

issue

5

eissn

2405-8033

issn

2405-8025

journal_volume

2

pub_type

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