Abstract：
:Curative therapy for cancer patients with advanced-stage disease remains elusive. While rare outlier responses to anticancer therapies exist, barriers limit our understanding of the molecular and genetic basis of such profound, life-altering responses. Here, we describe how phenotype-to-genotype studies are elucidating the molecular underpinnings of outlier responses and informing strategies to extend such unprecedented sensitivity to broader molecularly defined patient populations.
journal_name
Trends Cancerjournal_title
Trends in cancerauthors
Jonsson P,Taylor BSdoi
10.1016/j.trecan.2017.11.004subject
Has Abstractpub_date
2018-01-01 00:00:00pages
3-6issue
1eissn
2405-8033issn
2405-8025pii
S2405-8033(17)30216-9journal_volume
4pub_type
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