Effect of alpha-1-blockade by prazosin on blood sugar, insulin and glucagon levels in normals and non-insulin dependent diabetics.

abstract：:According to recent studies showing the presence of estrogens receptors (ERs) in the human female lower urinary tract, we performed ER and progesterone receptor (PR) assays in fresh frozen and paraffin embedded biopsies taken from the urinary bladder. Fourteen females undergoing endoscopy during staging for gynecologi...

journal_title：Journal of endocrinological investigation

authors： Pacchioni D,Revelli A,Casetta G,Cassoni P,Piana P,Tizzani A,Bussolati G,Massobrio M

更新日期：1992-11-01 00:00:00

abstract：:Monolayer cultures of medullary thyroid carcinoma (MTC) cells were prepared from 5 patients with familial and 4 with sporadic MTC. Basal calcitonin (CT) release decreased rapidly during 17 days in culture. Addition of extra calcium (2 mmol/l) or dibutyryl cyclic AMP (dBcAMP, 3 mmol/l) increased CT release in all inves...

journal_title：Journal of endocrinological investigation

authors： Oosterom R,Verleun T,Bruining HA,Hackeng WH,Lamberts SW

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVE:Aim of this study is to report on basal clinical phenotype and follow up after diagnosis, of patients with 17beta-hydroxysteroid-dehydrogenase type 3 (17beta-HSD3) deficiency in Italy. SETTING:Pediatric Endocrine Departments, University Hospitals. PATIENTS:The cases of 5 Italian subjects affected by 17beta-...

journal_title：Journal of endocrinological investigation

authors： Bertelloni S,Balsamo A,Giordani L,Fischetto R,Russo G,Delvecchio M,Gennari M,Nicoletti A,Maggio MC,Concolino D,Cavallo L,Cicognani A,Chiumello G,Hiort O,Baroncelli GI,Faienza MF

更新日期：2009-09-01 00:00:00

abstract：:This is a brief case report on a four-month-old girl who was admitted for failure to thrive and moderate dehydration. On admission she was mildly dehydrated and undernourished but with otherwise normal physical findings. Laboratory investigation disclosed mild but constant hyponatremia and hyperkalemia, very high plas...

journal_title：Journal of endocrinological investigation

authors： Mardesić D,Sarnavka V,Dumić M,Stipić V

更新日期：1992-03-01 00:00:00

abstract：:In healthy pregnant women, the regulation of thyroid function depends upon several factors. Three factors act independently to increase thyroid hormone requirements: 1) the marked increase in the binding capacity of serum due to high TBG levels; 2) the direct stimulation of the thyroid by human chorionic gonadotropin,...

journal_title：Journal of endocrinological investigation

authors： Glinoer D

更新日期：1993-05-01 00:00:00

abstract：:The long-acting somatostatin analogue SMS 201-995 has been used efficaciously in the therapy of metastatic carcinoid tumor, vasoactive intestinal peptide producing islet cell carcinoma, acromegaly, and TSH secreting pituitary tumors. We report the development of a gallstone in a patient treated for 23 months with a lo...

journal_title：Journal of endocrinological investigation

authors： Roti E,Minelli R,Gardini E,Salvi M,Bianconi L,Balducci L,Manfredi A,Braverman LE

更新日期：1990-01-01 00:00:00

abstract：:Thyrotoxicosis factitia, a syndrome due to the surreptitious ingestion of excess thyroid hormones, has generally been diagnosed in young or middle-aged women with psychopathological disturbances. We reviewed all the cases seen at our Institution over a 24-yr period, from 1973 to 1996. All 25 patients were women. Analy...

journal_title：Journal of endocrinological investigation

authors： Bogazzi F,Bartalena L,Scarcello G,Campomori A,Rossi G,Martino E

更新日期：1999-02-01 00:00:00

abstract：:Pheochromocytoma resection is often complicated by intra-operative hypertension and post-resection hypotension. Factors associated with these hemodynamic alterations are not well defined. The aim of this study was to analyse the clinical-laboratory features associated with hemodynamic parameters during pheochromocytom...

journal_title：Journal of endocrinological investigation

authors： Kramer CK,Leitão CB,Azevedo MJ,Canani LH,Maia AL,Czepielewski M,Paggi A,Rodrigues TC,Silveiro SP,Friedman R,Gross JL

更新日期：2009-03-01 00:00:00

abstract：:The regulation of GH secretion involves the harmonious integration of factors acting at the hypothalamic and pituitary levels summating to produce the peripheral patterns of intermittent GH secretion observed in man and experimental animals under physiologic and experimental conditions. SRIH and GHRH act primarily at ...

journal_title：Journal of endocrinological investigation

authors： Root AW

更新日期：1989-01-01 00:00:00

abstract：:Somatostatin and its derivatives have been predominantly studied and succesfully used in endocrinological diseases. This article reviews the rationale of the use of somatostatin and its derivatives in ophthalmology based on current understanding of its action in the eye and summarizes previously published controlled s...

journal_title：Journal of endocrinological investigation

authors： Missotten T,Baarsma GS,Kuijpers RW,van den Born LI,van der Loos T,Croxen R,Hofland LJ,van Hagen PM

更新日期：2005-01-01 00:00:00

abstract：:Entering puberty is one of the most important milestones in life. Studies from around the world have shown that age of pubertal changes onset can vary with race and ethnicity, environmental conditions, geographical location and nutrition. In the last century, the onset of puberty progressively shifted back towards you...

journal_title：Journal of endocrinological investigation

authors： Castellino N,Bellone S,Rapa A,Vercellotti A,Binotti M,Petri A,Bona G

更新日期：2005-07-01 00:00:00

abstract：AIM:This 3-month study compared the effect on overall glycemic control of adding biphasic insulin aspart 30 (BIAsp30) and premixed human insulin 30/70 (BHI30) to metformin (met) in insulin-naïve, obese patients (30 males/20 females) with Type 2 diabetes (T2DM). MATERIAL/SUBJECTS: At baseline, patients had a mean age of...

journal_title：Journal of endocrinological investigation

authors： Velojic-Golubovic M,Mikic D,Pesic M,Dimic D,Radenkovic S,Antic S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Vitamin D exerts pleiotropic effects and few studies are available in the Italian population. AIM:Aim of our study was to evaluate vitamin D status in children living in Northern Italy. METHODS:We studied vitamin D levels in a population of 113 normal weight (NW) and 444 obese (OB) children, prepubertal an...

journal_title：Journal of endocrinological investigation

authors： Bellone S,Esposito S,Giglione E,Genoni G,Fiorito C,Petri A,Bona G,Prodam F

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:Focal thyroid incidentaloma (TI) occurs in a 2% of 18F-FDG PET/CT and about one-third of TIs is cancer. Due to the lack of evidence on the optimal management of TI, current guidelines suggest performing fine-needle aspiration cytology (FNA). The study aim was to evaluate the reliability of ACR-TIRADS, EU-TIRA...

journal_title：Journal of endocrinological investigation

authors： Trimboli P,Knappe L,Treglia G,Ruberto T,Piccardo A,Ceriani L,Paone G,Giovanella L

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:Polycystic ovary syndrome (PCOS) was associated with a number of polymorphisms of genes involved in insulin signaling. So far, they have been studied separately. The aim of this study was to verify the impact of the coexistence of two polymorphisms of insulin signaling. METHODS:One hundred consecutive PCOS wom...

journal_title：Journal of endocrinological investigation

authors： Pappalardo MA,Vita R,Di Bari F,Le Donne M,Trimarchi F,Benvenga S

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:In contrast with maximal voluntary resistance exercise, which is allegedly considered a potent GH stimulus in young subjects, evaluation of GH response to whole-body vibrations (WBV) has yielded conflicting results. METHODS:The acute effects of WBV alone (test A), maximal voluntary isometric contractions (M...

journal_title：Journal of endocrinological investigation

authors： Sartorio A,Agosti F,De Col A,Marazzi N,Rastelli F,Chiavaroli S,Lafortuna CL,Cella SG,Rigamonti AE

更新日期：2011-03-01 00:00:00

abstract：:Signals that determine skeletal cell fate, function and apoptosis are critical to normal bone remodeling. Skeletal cells synthesize growth factors; some regulate cell replication, others regulate osteoblastic differentiation. Bone morphogenetic proteins (BMP) and Wnts induce the differentiation of mesenchymal cells to...

journal_title：Journal of endocrinological investigation

authors： Canalis E,Deregowski V,Pereira RC,Gazzerro E

更新日期：2005-01-01 00:00:00

abstract：:To evaluate the effect of weight loss and diet therapy on plasma sex hormone behavior in male obesity, 9 men with a BMI of 43.4 +/- 6.3 participated in an 8-week semistarvation program [whose energy content ranged from 320 to 500 k calorie/day (proteins 44 to 60 g and carbohydrates 54 to 81 g per day)] followed by a t...

journal_title：Journal of endocrinological investigation

authors： Pasquali R,Casimirri F,Melchionda N,Fabbri R,Capelli M,Platè L,Patrono D,Balestra V,Barbara L

更新日期：1988-03-01 00:00:00

abstract：:Few data are available on serum free thyroid hormone concentration in patients with T3-toxicosis. In this study total and free T4 and T3 and TBG were evaluated in 35 subjects with T3-toxicosis, including 12 with untreated Graves' disease, 5 Graves' patients on methimazole treatment, 13 with autonomous adenoma, 3 with ...

journal_title：Journal of endocrinological investigation

authors： Ferrari C,Romussi M,Rampini P,Benco R,Boghen M,Paracchi A,Frezzati S

更新日期：1983-02-01 00:00:00

abstract：:To verify if the entity of the peak GH responses to the GHRH+arginine (ARG) test is able to show different degree forms of GH deficiency (GHD), we linked these responses with the number of other anterior pituitary deficits. These anterior pituitary deficits were also related with IGF-I levels. To this purpose, we stud...

journal_title：Journal of endocrinological investigation

authors： Aimaretti G,Corneli G,Di Somma C,Baldelli R,Gasco V,Rovere S,Migliaretti G,Colao A,Tamburrano G,Lombardi G,Ghigo E,Camanni F

更新日期：2005-03-01 00:00:00

abstract：:Many studies have shown that fat distribution influences metabolism independently of the effects of total body fat stores. The accumulation of fat in the abdominal area, particularly in the visceral fat compartment, seems to be associated with an increased risk to display complications such as insulin resistance, diab...

journal_title：Journal of endocrinological investigation

authors： Gasteyger C,Tremblay A

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:The diagnosis of polycystic ovary syndrome (PCOS) is based on a combination of various clinical phenotypes in each patient. However, insulin resistance (IR) and dysmetabolism are not included in the diagnostic criteria of PCOS. Therefore, the definition of PCOS is controversial. The objective of this study is t...

journal_title：Journal of endocrinological investigation

authors： Zhang L,Fang X,Li L,Liu R,Zhang C,Liu H,Tan M,Yang G

更新日期：2018-12-01 00:00:00

abstract：:Among the several antigens involved in autoimmune thyroid diseases, the microsomal antigen has been recently identified as the human thyroid peroxidase (TPO). The availability of highly purified TPO and anti-TPO monoclonal antibody (mAb) allowed us to study in more details anti-TPO autoimmune antibodies (aAb) and thei...

journal_title：Journal of endocrinological investigation

authors： Czarnocka B,Ruf J,Ferrand M,Lissitzky S,Carayon P

更新日期：1986-04-01 00:00:00

abstract：:Somatostatin has been found in the pineal gland of several animal species, which suggests that it may be involved in the regulation of melatonin secretion. Whether somatostatin has regulatory influence on melatonin secretion in man has never been unequivocally shown. We studied the nocturnal melatonin secretion in 8 h...

journal_title：Journal of endocrinological investigation

authors： Wikner J,Wetterberg L,Röjdmark S

更新日期：1999-07-01 00:00:00

abstract：:There is increasing evidence that androgen therapy in men may be effectively applied in several conditions to improve well being and health. Classical indications for androgen therapy in males are represented by primary or secondary hypogonadism, delayed puberty, aplastic anemia and that secondary to chronic renal fai...

journal_title：Journal of endocrinological investigation

authors： Gambineri A,Pasquali R

更新日期：2000-03-01 00:00:00

abstract：:Adrenal origin and ACTH-dependent secretion of endogenous digitalis-like factor(s) (EDLF) was investigated. Twelve normal weight normotensive subjects (normal group) and 10 patients with Addison's disease (Addison group) were subjected to prolonged ACTH stimulation with 1 mg tetracosactin-depot im. Blood sampling was ...

journal_title：Journal of endocrinological investigation

authors： Sophocleous A,Elmatzoglou I,Souvatzoglou A

更新日期：2003-07-01 00:00:00

abstract：COPEPTIN:Copeptin is secreted in equimolar amount to Arginine Vasopressin (AVP) but can easily be measured with a sandwich immunoassay. Both peptides, copeptin and AVP, show a high correlation. Accordingly, copeptin mirrors the amount of AVP in the circulation and its measurement provides an attractive marker in the di...

journal_title：Journal of endocrinological investigation

authors： Christ-Crain M,Fenske WK

更新日期：2020-01-01 00:00:00

abstract：:N-Methyl-D-Aspartate(NMDA)-sensitive glutamate receptors, are critically involved in the induction of the learning process. Activation of NMDA receptors by glutamate lead to massive influx of extracellular Ca2+, with ensuing activation of a variety of Ca(2+)-dependent enzymes, including protein kinase C. This triggers...

journal_title：Journal of endocrinological investigation

authors： Caruso S,Agnello C,Campo MG,Nicoletti F

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Elevated γ-glutamyl transpeptidase (GGT) and alanine aminotransferase (ALT) could predict the risk of Type 2 diabetes (T2D), but the reason for their elevation was unclear. GGT and ALT mediated the metabolism of many amino acids (AA). Up to now, it was not investigated whether abnormal AA concentration was a...

journal_title：Journal of endocrinological investigation

authors： Chen T,Zhang X,Long Y,Yu H,Ran X,Gao Y,Lu H,Xie X,Chen X,Ren Y,Shi J,Tian H

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:Graves' orbitopathy (GO) is an inflammatory orbital disease of autoimmune origin with the potential to cause severe functional and psychosocial effects. The pathogenesis has not been fully elucidated. We investigated whether DNA methylation was associated with GO incidence in Chinese patients. MATERIALS AND ...

journal_title：Journal of endocrinological investigation

authors： Xin Z,Hua L,Shi TT,Tuo X,Yang FY,Li Y,Cao X,Yang JK

更新日期：2018-06-01 00:00:00