Study of potential inhibitors of thyroid iodide uptake by using CHO cells stably expressing the human sodium/iodide symporter (hNIS) protein.

abstract：:N-Methyl-D-Aspartate(NMDA)-sensitive glutamate receptors, are critically involved in the induction of the learning process. Activation of NMDA receptors by glutamate lead to massive influx of extracellular Ca2+, with ensuing activation of a variety of Ca(2+)-dependent enzymes, including protein kinase C. This triggers...

journal_title：Journal of endocrinological investigation

authors： Caruso S,Agnello C,Campo MG,Nicoletti F

更新日期：1993-12-01 00:00:00

abstract：:Volume receptors are situated in many organs and are capable of modulating ADH secretion. We have evaluated the variation of plasma ADH concentration after an experimentally induced increase of cerebrospinal fluid (CSF) pressure (PCSF). The experiment was performed in controlled environmental conditions to avoid pain ...

journal_title：Journal of endocrinological investigation

authors： Satta A,Palomba D,Demontis MP,Varoni MV,Faedda R,Ginanni A,Anania V

更新日期：1996-07-01 00:00:00

abstract：:Traumatic brain injury (TBI)-induced hypopituitarism remains a relevant medical problem, because it may affect a significant proportion of the population. In the last decade important studies have been published investigating pituitary dysfunction after TBI. Recently, a group of experts gathered and revisited the topi...

journal_title：Journal of endocrinological investigation

authors： Tanriverdi F,Agha A,Aimaretti G,Casanueva FF,Kelestimur F,Klose M,Masel BE,Pereira AM,Popovic V,Schneider HJ

更新日期：2011-07-01 00:00:00

abstract：:The differential diagnosis of an osteoblastic vertebral lesion (ivory vertebra) includes metastatic prostate cancer, lung cancer, lymphoma, osteosarcoma and Paget's disease. We report a case of a man who was initially diagnosed with Paget's disease on vertebral biopsy. He failed to respond to conventional bisphosphate...

journal_title：Journal of endocrinological investigation

authors： Basaria S,McCarthy EF,Belzberg AJ,Ball DW

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of testosterone treatment on biomarkers calprotectin, fibroblast growth factor 23 (FGF23), soluble Klotho, phosphate, calcium, parathyroid hormone, creatinine and estimated glomerular filtration rate. DESIGN:Randomized, double-blinded, placebo-controlled study. SETTING:Odense Andr...

journal_title：Journal of endocrinological investigation

authors： Pedersen L,Christensen LL,Pedersen SM,Andersen M

更新日期：2017-05-01 00:00:00

abstract：:The effect of exogenous prednisone on serum thyrotropin (TSH), thyroxine (T4), and triiodothyronine (T3) concentrations was investigated in four patients with non-functioning thyroid glands receiving T4 replacement therapy. Orally administered prednisone, in a dose of 20 mg each day for nine days, resulted in a signif...

journal_title：Journal of endocrinological investigation

authors： Jensen J,Nolan G,Jubiz W

更新日期：1978-04-01 00:00:00

abstract：:The occurrence of metabolic bone disease in patients with renal dysfunction is due to the key role played by the kidney in regulating calcium-phosphate metabolism. The incidence of hip fractures in end-stage renal disease is 3- to 4-fold higher than the general population, while poor data about vertebral fractures sho...

journal_title：Journal of endocrinological investigation

authors： Fusaro M,D'Angelo A,Scalzo G,Gallieni M,Giannini S,Guglielmi G

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:The relative contribution of fasting and post-prandial glucose to glycated hemoglobin (HbA1c) is controversial. In the present study, we assessed the relationship with HbA1c of fasting and post-prandial glucose measured in a more naturalistic setting, through home glucose self-monitoring or with a continuous ...

journal_title：Journal of endocrinological investigation

authors： Monami M,Lamanna C,Lambertucci L,Longo R,Cocca C,Addante F,Lotti E,Masotti G,Marchionni N,Mannucci E

更新日期：2006-07-01 00:00:00

abstract：:Abnormalities of the gene encoding the sequence-specific DNA-binding protein, nuclear phosphorprotein p53, are among the most common genetic alterations observed in human cancers. A mutation of this tumor suppressor gene has been reported with a low prevalence in differentiated thyroid carcinomas, while the prevalence...

journal_title：Journal of endocrinological investigation

authors： Iyota K,Takeda K,Matsuzuka F,Okabayashi T,Morita S,Kuma K,Hashimoto K

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Serum DHEAS has been found to be elevated in some women with polycystic ovary syndrome (PCOS). We wished to determine whether this prevalence is different in women with androgen excess who have different phenotypes and to correlate these findings with various cardiovascular and metabolic parameters. METHODS...

journal_title：Journal of endocrinological investigation

authors： Carmina E,Lobo RA

更新日期：2007-02-01 00:00:00

abstract：:A patient with Graves' disease associated with severe muscle weakness who was finally diagnosed as polymyositis by pathological examination of the muscle is reported. A 28-year-old women was incidentally found to have hyperthyroidism when she consulted a hospital for the evaluation and treatment of anemia in 1979. She...

journal_title：Journal of endocrinological investigation

authors： Sakata S,Fuwa Y,Goshima E,Nakamura S,Yamakita N,Maeda M,Miura K

更新日期：1989-12-01 00:00:00

abstract：:Pituitary adenomas are common neoplasms requiring medical and/or surgical treatment when associated with hormonal hypersecretion. Treatment of non-functioning pituitary adenomas is necessary when symptoms of mass effect or hormonal deficits occur. However, therapeutic options, including surgical resection and/or radio...

journal_title：Journal of endocrinological investigation

authors： Ballian N,Chrisoulidou A,Nomikos P,Samara C,Kontogeorgos G,Kaltsas GA

更新日期：2007-09-01 00:00:00

abstract：:There has been a substantial increase in women practicing sports over the past 30 yr. While exercise provides many health benefits, there appears to be a unique set of risks associated with intense exercise for the female athlete. The female athlete triad encompasses these risks, including amenorrhea, osteoporosis and...

journal_title：Journal of endocrinological investigation

authors： Warren MP,Goodman LR

更新日期：2003-09-01 00:00:00

abstract：:An immunohistochemical study with two rabbit polyclonal antibodies I-AR76 and CA-08-351 against Endothelin-1 (ET-1) was performed in 133 human thyroid specimens: 5 normal thyroids, 30 multinodular goiters (15 toxic and 15 nontoxic), 20 Graves' diseases, 5 Hashimoto's thyroiditis, 26 adenomas (6 Hürthle cell, 16 toxic ...

journal_title：Journal of endocrinological investigation

authors： Lenziardi M,Viacava P,Fiorini I,Castagna M,Nardini V,Pollina L,De Negri F,Goletti O,Di Coscio G,Bevilacqua G

更新日期：1995-05-01 00:00:00

abstract：:Preliminary hormonal studies in a 18-y old man with the clinical features of Cushing's syndrome showed inconclusive and conflicting results both in basal conditions and after metyrapone and dexamethasone administration. Therefore the possibility of a cyclical or acyclical fluctuation of adrenal hypersecretion was susp...

journal_title：Journal of endocrinological investigation

authors： De Feo ML,Bonfanti L,Romano S,Fusi S,Giusti G,Messeri G,Forti G

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:One of the major topics in modern societies is the study of relationships between diet, stress and incidence of metabolic disorders. AIM:This study aimed to investigate possible impairment in glucose-stimulated insulin secretion induced by a high-fat (cow intra-abdominal fat) diet in response to acute stres...

journal_title：Journal of endocrinological investigation

authors： Ghalami J,Zardooz H,Rostamkhani F,Farrokhi B,Hedayati M

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Adipose tissue has been suggested to influence bone density and metabolism through the effect of some adipokines. However, whether adiponectin and visfatin may correlate with bone metabolism is still unclear. AIM:The aim of this study was to investigate the relationship of adiponectin and visfatin with bone...

journal_title：Journal of endocrinological investigation

authors： Iacobellis G,Iorio M,Napoli N,Cotesta D,Zinnamosca L,Marinelli C,Petramala L,Minisola S,D'Erasmo E,Letizia C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors determine a wide reduction of LDL cholesterol, greater than other lipid-lowering agents. The present meta-analysis is aimed at the assessment of PCSK9 inhibitors effect on LDL Cholesterol, cardiovascular morbidity and all-cause mortali...

journal_title：Journal of endocrinological investigation

authors： Dicembrini I,Giannini S,Ragghianti B,Mannucci E,Monami M

更新日期：2019-09-01 00:00:00

abstract：:Established methods for definitive ablation of autonomous thyroid nodules are surgery and radioiodine. Since it has been demonstrated that percutaneous ethanol injection can inactivate parathyroid adenomas and small hepatocellular carcinomas, we started a trial of this treatment in patients with autonomous thyroid nod...

journal_title：Journal of endocrinological investigation

authors： Paracchi A,Ferrari C,Livraghi T,Reschini E,Macchi RM,Bergonzi M,Raineri P

更新日期：1992-05-01 00:00:00

abstract：:Impaired glucose tolerance is present in many acromegalic patients and treatment with somatostatin analogs has variable effects on glycemic control. The aim of this study was to compare the effects of 2 somatostatin analogs on glucose metabolism, lanreotide slow release (L-SR) and octreotide long acting release (O-LAR...

journal_title：Journal of endocrinological investigation

authors： Ronchi C,Epaminonda P,Cappiello V,Beck-Peccoz P,Arosio M

更新日期：2002-06-01 00:00:00

abstract：:Erectile dysfunction (ED) increases in prevalence and severity because of aging processes and related organic, iatrogenic and social problems. Decline of testosterone (T) levels is observed with age and also in illnesses with a common basis of endothelial damage. The T deficiency may lead to decreased energy, mood dep...

journal_title：Journal of endocrinological investigation

authors： Frajese GV,Pozzi F

更新日期：2005-01-01 00:00:00

abstract：:The effects of short term administration of 200 MRC U of synthetic salmon calcitonin (sCT) daily on carbohydrate metabolism were investigated in 10 patients with various bone diseases, 3 of whom had type II diabetes mellitus and 3 of whom had impaired glucose tolerance. Blood glucose levels during the nocturnal postab...

journal_title：Journal of endocrinological investigation

authors： Giustina G,Cerudelli B,Cimino A,Rigosa C,Rotondi A,Radaeli E

更新日期：1985-02-01 00:00:00

abstract：:Cardiovascular problems have long been recognized as responsible for an increased morbidity and mortality in patients with acromegaly. The aim of the present study was to evaluate echocardiographically the prevalence of cardiomyopathy in a cohort of acromegalic patients and to analyze the results in relation to demogr...

journal_title：Journal of endocrinological investigation

authors： Terzolo M,Avonto L,Matrella C,Pozzi R,Luceri S,Borretta G,Pecchio F,Ugliengo G,Magro GP,Reimondo G

更新日期：1995-09-01 00:00:00

abstract：:The effects of estriol on serum prolactin (PRL) and LH levels, on the pituitary response to TRH and LHRH and on the synthesis and release of PRL from the anterior pituitary gland were investigated in female rats. The increase of serum PRL levels after estradiol administration was found to be associated with an increas...

journal_title：Journal of endocrinological investigation

authors： Diaz MC,Seilicovich A,Duvilanski BH,Siseles N,Lasaga M,Debeljuk L

更新日期：1989-01-01 00:00:00

abstract：:Molecular diagnostics of the LHR gene was conducted in a 5-year-old boy with clinical symptoms and hormonal profile typical of precocious puberty. His parents and 4 sisters were also diagnosed. Single-strand conformation polymorphism analysis under temperature gradient conditions (Multitemperature SSCP) of 3 overlappi...

journal_title：Journal of endocrinological investigation

authors： Ignacak M,Starzyk J,Dziatkowiak H,Trzeciak WH

更新日期：2002-03-01 00:00:00

abstract：INTRODUCTION:No data on the prevalence of erectile dysfunction (ED) in subjects with newly diagnosed Type 2 diabetes mellitus (T2DM) are currently available. AIM:The aim of the present study was to estimate the prevalence of ED and its associated causes in a sample of male patients with recently diagnosed DM (<24 mont...

journal_title：Journal of endocrinological investigation

authors： Corona G,Giorda CB,Cucinotta D,Guida P,Nada E,SUBITO-DE study group.

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:Spinal cord injury (SCI) affects sexual health of both male and female, but little attention has been given to sexuality of SCI women. Similar to penile erection, vaginal lubrication represents a neurovascular event and then both denervation and vascular damage might contribute to its impairment. Nevertheless, ...

journal_title：Journal of endocrinological investigation

authors： D'Andrea S,Castellini C,Paladino V,Totaro M,Felzani G,Francavilla S,Francavilla F,Barbonetti A

更新日期：2020-07-01 00:00:00

abstract：:Isolated hypothyroxinemia (IH) is defined as a thyroxine level in the lower 5th (severe IH) or 10th percentile (mild IH) of the pregnancy-related reference range and a normal TSH. The etiology of IH remains unknown. This review aims to evaluate the biochemical criteria used to define IH in different published studies ...

journal_title：Journal of endocrinological investigation

authors： Furnica RM,Lazarus JH,Gruson D,Daumerie C

更新日期：2015-02-01 00:00:00

abstract：AIM:We aimed to investigate serum nesfatin-1 level in girls with premature thelarche (PT) and its relationship with anthropometric parameters and leptin, which are involved in the initiation of pubertal process. SUBJECTS-METHODS:Non-obese girls who presented with the complaint of early (2-8 years) and isolated breast ...

journal_title：Journal of endocrinological investigation

authors： Çatlı G,Anık A,Küme T,Çalan ÖG,Dündar BN,Böber E,Abacı A

更新日期：2015-08-01 00:00:00

abstract：:The aim of this prospective study was to investigate the effects of thyroid hormone levels on the sepsis criteria and mortality in septic newborns. This study was performed at the Firat University Hospital Neonatal Intensive Care Unit. A group of septic newborns and a control group of healthy non-infected newborns wer...

journal_title：Journal of endocrinological investigation

authors： Kurt A,Aygun AD,Sengul I,Sen Y,Citak Kurt AN,Ustundag B

更新日期：2011-04-01 00:00:00