Spontaneous regression of hypercalcemia in a patient with primary hyperparathyroidism and prolactinoma.

abstract：:In a 12-yr-old boy growth arrest occurred after severe head trauma. Evaluation of pituitary endocrine function revealed isolated growth hormone (GH) deficiency. Lack of GH response to GH-releasing factor indicated that the responsible lesion was most likely to be localized in the pituitary gland. GH substitution resul...

journal_title：Journal of endocrinological investigation

authors： Eichler I,Frisch H,Eichler HG,Soukop W

更新日期：1988-06-01 00:00:00

abstract：:Glucocorticoid receptors (GR) and 3-O-methyl-D glucose (3-O-MG) transport were determined in mononuclear leukocytes (MNL) from 11 abdominal obese subjects, 10 pituitary-dependent Cushing's syndrome (Cushing's disease) and 10 healthy controls. Using a whole-cell competitive binding assay and 3H-dexamethasone as tracer,...

journal_title：Journal of endocrinological investigation

authors： Güven M,Hatemi H,Taşan E,Altuntaş Y,Ulutin T,Tezcan V,Kanigür-Sultuybek G

更新日期：1998-11-01 00:00:00

abstract：:Human GH (hGH) is a heterogeneous protein hormone consisting of several isoforms. This heterogeneity is the consequence of multiple hGH genes, mRNA splicing, post-translational modifications, and peripheral metabolism, and it represents one important reason for the disparity among GH assay results from different labor...

journal_title：Journal of endocrinological investigation

authors： Rigamonti AE,Bozzola M,Banfi G,Meazza C,Müller EE,Cella SG

更新日期：2012-11-01 00:00:00

abstract：:Somatostatin and its derivatives have been predominantly studied and succesfully used in endocrinological diseases. This article reviews the rationale of the use of somatostatin and its derivatives in ophthalmology based on current understanding of its action in the eye and summarizes previously published controlled s...

journal_title：Journal of endocrinological investigation

authors： Missotten T,Baarsma GS,Kuijpers RW,van den Born LI,van der Loos T,Croxen R,Hofland LJ,van Hagen PM

更新日期：2005-01-01 00:00:00

abstract：:Thyroid function tests were evaluated in 34 patients with acute viral hepatitis (AVH) and in 38 healthy controls (C). As expected, AVH patients displayed a significant increase in T4, rT3 and TBG serum levels with respect to C, while FT4 and TSH concentrations were similar. A positive correlation between TBG and T4 wa...

journal_title：Journal of endocrinological investigation

authors： Pagliacci MC,Pelicci G,Francisci D,Giammartino C,Fedeli L,Stagni G,Nicoletti I

更新日期：1989-03-01 00:00:00

abstract：:Disulfide bonds are formed between the sulfhydryl groups in two cysteine residues of a protein. The formation of these bonds is necessary for the proper folding of a protein into its active three-dimensional form. In this study, the genes associated with disulfide bond formation of proteins from the rat thyroid cell l...

journal_title：Journal of endocrinological investigation

authors： Park S,Hwang I,Shong M,Kwon OY

更新日期：2003-02-01 00:00:00

abstract：:Nutritional and hormonal milieu in utero affect fetal growth. Both parties involved have an independent chance, for the occurrence of a developmental error at any stage of their constant developing system. Studies suggest that pregnancy outcome is associated with fetal demand for nutrients and the materno-placental ca...

journal_title：Journal of endocrinological investigation

authors： Zadik Z

更新日期：2003-09-01 00:00:00

abstract：:Microvessel density (MVD) represents a measure of angiogenesis and may be used as an indicator of neoplastic aggressiveness. Vascular endothelial growth factor (VEGF) plays a pivotal role as angiogenic promoter by stimulating endothelial cell proliferation and migration and enhancing vascular permeability. The aim of ...

journal_title：Journal of endocrinological investigation

authors： Viacava P,Gasperi M,Acerbi G,Manetti L,Cecconi E,Bonadio AG,Naccarato AG,Acerbi F,Parenti G,Lupi I,Genovesi M,Martino E

更新日期：2003-01-01 00:00:00

abstract：:Effects of primary hypothyroidism (HYPO) on the male gonadal axis are controversial, with only scanty data on the gonadotroph cell response and no information on GnRH tuberoinfundibular neurons, even in animal models. HYPO has been reported to variably induce hypogonadotropic hypogonadism, a hypergonadotropic state, o...

journal_title：Journal of endocrinological investigation

authors： Toni R,Della Casa C,Castorina S,Cocchi D,Celotti F

更新日期：2005-01-01 00:00:00

abstract：:Hypoparathyroidism cannot be cured by oral or intravenous calcium supplements. Using molecular biology techniques to induce the production of PTH is an ideal option to treat hypoparathyroidism. In this study, we established a recombinant plasmid encoding a mutant preproPTH with a skeletal muscle creatine kinase promot...

journal_title：Journal of endocrinological investigation

authors： Liu D,Zhu Y,Yang C,Long J,Yao C,Li J,Wang S

更新日期：2012-05-01 00:00:00

abstract：:The cause of a poor response to human menopausal gonadotropin (hMG) remains unexplained. To determine whether aromatase activity of cultured granulosa cells obtained from relatively low estradiol (E2) responders (serum E2 < 1000 pg/ml) to hMG therapy differed from that of good responders (E2 > or = 1000 pg/ml), we pro...

journal_title：Journal of endocrinological investigation

authors： Hurst BS,Zacur HA,Schlaff WD,Berkovitz GD

更新日期：1992-09-01 00:00:00

abstract：:Plasma levels and 24-h urinary excretion of cyclic AMP and cyclic GMP were measured in 18 patients with hyperthyroidism, 7 patients with hypothyroidism and 25 normal subjects. Mean plasma and urinary levels of both cyclic AMP and cyclic GMP were significantly positive correlations between the serum thyroid hormone lev...

journal_title：Journal of endocrinological investigation

authors： Peracchi M,Bamonti-Catena F,Lombardi L,Reschini E,Toschi V,Maiolo AT,Polli EE

更新日期：1983-06-01 00:00:00

abstract：:Many studies have shown that fat distribution influences metabolism independently of the effects of total body fat stores. The accumulation of fat in the abdominal area, particularly in the visceral fat compartment, seems to be associated with an increased risk to display complications such as insulin resistance, diab...

journal_title：Journal of endocrinological investigation

authors： Gasteyger C,Tremblay A

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:Primary hyperparathyroidism has deleterious effects on health and causes nephrolithiasis and osteoporosis. However, it remains unclear whether parathyroidectomy benefits kidney function among patients with primary hyperparathyroidism. METHODS:In this retrospective study, patients with primary hyperparathyroidi...

journal_title：Journal of endocrinological investigation

authors： Liang CC,Yeh HC,Lo YC,Chou CY,Yen TH,Tsai HC,Hsu SP,Kuo CC

更新日期：2020-07-29 00:00:00

abstract：:In healthy pregnant women, the regulation of thyroid function depends upon several factors. Three factors act independently to increase thyroid hormone requirements: 1) the marked increase in the binding capacity of serum due to high TBG levels; 2) the direct stimulation of the thyroid by human chorionic gonadotropin,...

journal_title：Journal of endocrinological investigation

authors： Glinoer D

更新日期：1993-05-01 00:00:00

abstract：:It has been reported that adult obese subjects present a reduced growth hormone secretion. As no data are available in the pubertal period, which is characterized in lean subjects by an increased spontaneous growth hormone secretion, the growth hormone circadian concentration was studied in a group of 18 obese male su...

journal_title：Journal of endocrinological investigation

authors： Minuto F,Barreca A,Del Monte P,Fortini P,Resentini M,Morabito F,Giordano G

更新日期：1988-07-01 00:00:00

abstract：:D-aspartic acid (D-Asp), aromatase enzyme activity and the putative D-Asp involvement on aromatase induction have been studied in the testis of mature boars. The peroxidase-antiperoxidase and the indirect immunofluorescence methods, applied to cryostat and paraffin sections, were used to evaluate D-Asp and aromatase d...

journal_title：Journal of endocrinological investigation

authors： Lamanna C,Assisi L,Botte V,Di Fiore MM

更新日期：2006-02-01 00:00:00

abstract：:The pineal gland contains many peptides known to be implicated in melatonin production. We examined the effects of a synthetic pineal tetrapeptide Ala-Glu-Asp-Gly on melatonin secretion by the pineal gland. The tetrapeptide effects on pineal gland melatonin secretion were studied in young (9 weeks) and old (27 months)...

journal_title：Journal of endocrinological investigation

authors： Djeridane Y,Khavinson VKh,Anisimov VN,Touitou Y

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:Uncertainties exist about the predictors of the severity of the clinical picture of GH deficiency (GHD) syndrome. Aim of the study was to evaluate, in adult patients with GHD, the predictors of the development of hypercholesterolemia, hypertension, diabetes mellitus, and osteoporosis. METHODS:We retrospectivel...

journal_title：Journal of endocrinological investigation

authors： Gasco V,Roncoroni L,Zavattaro M,Bona C,Berton A,Ghigo E,Maccario M,Grottoli S

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:Leptin is associated with cardiovascular risk factors (e.g. hypertension, insulin resistance, kidney disease and excess body weight). Experimental studies showed that leptin might affect serum uric acid, by modulation of the uric acid excretion. However, there are few observational data on the relationship betw...

journal_title：Journal of endocrinological investigation

authors： D'Elia L,Giaquinto A,Cappuccio FP,Iacone R,Russo O,Strazzullo P,Galletti F

更新日期：2020-05-01 00:00:00

abstract：:Patients with simple exogenous obesity are characterized by increased B-endorphin (B-EP) plasma levels, despite normal ACTH and B-Lipotropin (B-LPH). To evaluate the origin of such an hyperendorphinemia, 42 obese patients were submitted to a short overnight dexamethasone suppression test (DST: 1 mg at 23:00 h). Blood ...

journal_title：Journal of endocrinological investigation

authors： Facchinetti F,Giovannini C,Petraglia F,Barletta C,Comitini G,Genazzani AR

更新日期：1988-02-01 00:00:00

abstract：PURPOSE:This study aimed to investigate the interactive effect of polycystic ovary syndrome (PCOS) status and obesity status on the serum levels of adipokines. METHODS:In this comparative case-control cross-sectional study, 58 women with PCOS and 104 eumenorrheic non-hirsute women as the control group were recruited. ...

journal_title：Journal of endocrinological investigation

authors： Behboudi-Gandevani S,Ramezani Tehrani F,Bidhendi Yarandi R,Noroozzadeh M,Hedayati M,Azizi F

更新日期：2017-08-01 00:00:00

abstract：:The regulation of GH secretion involves the harmonious integration of factors acting at the hypothalamic and pituitary levels summating to produce the peripheral patterns of intermittent GH secretion observed in man and experimental animals under physiologic and experimental conditions. SRIH and GHRH act primarily at ...

journal_title：Journal of endocrinological investigation

authors： Root AW

更新日期：1989-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) combined with fractures of long bones or large joints is often associated with enhanced osteogenesis (early fracture healing accompanied by hypertrophic callus formation and/or heterotopic ossifications). Humoral factors that cause enhanced osteogenesis in patients with TBI are not yet ide...

journal_title：Journal of endocrinological investigation

authors： Wildburger R,Zarkovic N,Tonkovic G,Skoric T,Frech S,Hartleb M,Loncaric I,Zarkovic K

更新日期：1998-02-01 00:00:00

abstract：PURPOSE:The diagnosis of vitamin D deficiency is based on the determination of total plasma 25-hydroxyvitamin D (25-OHD) concentrations, but the regulation of vitamin D 25-hydroxylation is not a major consideration and very little information is available on this activity. To check what factors could interfere with the...

journal_title：Journal of endocrinological investigation

authors： Bellastella G,Scappaticcio L,Longo M,Carotenuto R,Carbone C,Caruso P,Maio A,Paglionico VA,Vietri MT,Maiorino MI,Esposito K

更新日期：2021-01-25 00:00:00

abstract：:Stroke is one of the main causes of death and disability in the adult population. Changes in pituitary hormone secretion may be observed during the acute phase of stroke, representing part of the adaptive response to injury. However, reduced pituitary hormone secretion, caused by pituitary and/or hypothalamus damage, ...

journal_title：Journal of endocrinological investigation

authors： Bondanelli M,Ambrosio MR,Zatelli MC,Basaglia N,Degli Uberti EC

更新日期：2008-09-01 00:00:00

abstract：:Papillary thyroid cancer (PTC) accounts for 80% of all thyroid malignancies, and genetic alterations associated to its etiology remain largely unknown. Chromosomal band 11q13 seems to be one of the most frequently amplified regions in human cancer, providing several candidate genes that need detailed characterization....

journal_title：Journal of endocrinological investigation

authors： Hidalgo M,Saez ME,Martinez-Tello FJ,Moron FJ,Ferrero-Herrero E,Labalde-Martinez M,Rigopoulou D,Ballestin-Carcavilla C,Ruiz A,Royo JL,Ramirez-Lorca R

更新日期：2008-07-01 00:00:00

abstract：:Not only thyroid adenomas and carcinomas, but also the majority of single and well delimited goiter nodules, even if morphologically heterogeneous, are of clonal origin. However, it is still unknown whether the nodules of rapidly growing, recurrent goiters are clonal or polyclonal. We investigated by PCR-based analysi...

journal_title：Journal of endocrinological investigation

authors： Harrer P,Broecker M,Zint A,Schatz H,Zumtobel V,Derwahl M

更新日期：1998-06-01 00:00:00

abstract：:Cimetidine, an H2 receptor antagonist, is a potent stimulant of PRL secretion in normal women. In the present study, the PRL response to cimetidine was studied in 34 normal pregnant women and their fetuses during labor. Serum maternal PRL levels increased significantly after the acute iv injection of 400 mg cimetidine...

journal_title：Journal of endocrinological investigation

authors： Messinis IE,Tsirkas N,Diamantis K,Vasakos S,Tsolas O,Lolis D

更新日期：1988-12-01 00:00:00

abstract：:We evaluated the oral calcium-loading test (OCLT) in diagnosing normocalcemic primary hyperparathyroidism. Calcium and PTH levels were measured before, 60, 120 and 180 min after oral 1 g of calcium gluconolactate administration in 102 consecutive females with high circulating PTH levels, and 25 controls. Patients were...

journal_title：Journal of endocrinological investigation

authors： Hagag P,Revet-Zak I,Hod N,Horne T,Rapoport MJ,Weiss M

更新日期：2003-04-01 00:00:00