Effect of cimetidine on maternal and fetal prolactin secretion during labor.

Abstract:

:Cimetidine, an H2 receptor antagonist, is a potent stimulant of PRL secretion in normal women. In the present study, the PRL response to cimetidine was studied in 34 normal pregnant women and their fetuses during labor. Serum maternal PRL levels increased significantly after the acute iv injection of 400 mg cimetidine 30-45 min before delivery (10 women) as compared to 7 control women given saline. However, PRL levels in serum of umbilical vein and artery did not increase. Similar results concerning PRL levels in umbilical vein and artery serum were obtained when cimetidine was injected 10-20 min (8 women), 60-75 min (8 women) and 90-120 min (8 women) before delivery. It is suggested that fetal pituitary lactotrops are not responsive to cimetidine stimulation.

journal_name

J Endocrinol Invest

authors

Messinis IE,Tsirkas N,Diamantis K,Vasakos S,Tsolas O,Lolis D

doi

10.1007/BF03350225

subject

Has Abstract

pub_date

1988-12-01 00:00:00

pages

785-8

issue

11

eissn

0391-4097

issn

1720-8386

journal_volume

11

pub_type

杂志文章
  • Pituitary-adrenal dynamics after ACTH-secreting pituitary tumor resection in patients receiving no steroids post-operatively.

    abstract::It has recently been suggested that the classical routine of glucocorticoid administration before and after transsphenoidal surgery (TSS) in Cushing's disease (CD) patients may not be necessary, since it is likely that peritumoral normal corticotrophs are not completely suppressed during this period. We compared the d...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347237

    authors: Pimentel-Filho FR,Silva ME,Nogueira KC,Berger K,Cukiert A,Liberman B

    更新日期:2005-06-01 00:00:00

  • Cortisol, dehydroepiandrosterone sulphate and dehydroepiandrosterone sulphate/cortisol ratio responses to physical stress in males are influenced by pubertal development.

    abstract::To evaluate the influence of chronological age and pubertal development on the hypothalamus-pituitary-adrenal (HPA) axis response to stress, we studied the possible correlations between male pubertal characteristics and salivary cortisol (C), DHEAS and the DHEAS/C ratio before (pre-stress) and after acute exercise-str...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347373

    authors: Di Luigi L,Guidetti L,Baldari C,Gallotta MC,Sgrò P,Perroni F,Romanelli F,Lenzi A

    更新日期:2006-10-01 00:00:00

  • Cardiovascular outcome trials and major cardiovascular events: does glucose matter? A systematic review with meta-analysis.

    abstract:PURPOSE:We did a meta-analysis with meta-regression to evaluate the relationship between hemoglobin A1c (A1C) reduction and the primary CV outcome of cardiovascular outcome trials (CVOTs). METHODS:We used a random effects meta-analysis of the 12 CVOTs to quantify the effect of A1C reduction on major cardiovascular eve...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,meta分析

    doi:10.1007/s40618-019-01047-0

    authors: Giugliano D,Chiodini P,Maiorino MI,Bellastella G,Esposito K

    更新日期:2019-10-01 00:00:00

  • Comparison of single and combined tests for the evaluation of plasma growth hormone secretion in normal short children.

    abstract::Growth hormone (GH) response to provocative tests was compared in normal short children. Seven of 23 children failed to respond to insulin hypoglycemia. Using insulin hypoglycemia followed by L-dopa only 2 of 23 children did not respond and giving bromocriptine combined with insulin hypoglycemia only 1 of 8 children f...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03351005

    authors: Bazán MC,Domené H,Heinrich JJ,Barontini M,Bergadá C

    更新日期:1984-08-01 00:00:00

  • Primary hypothyroidism associated with secondary adrenocortical insufficiency.

    abstract::A 50 year old man is described in whom primary hypothyroidism and isolated ACTH deficiency leading to adrenocortical insufficiency occurred simultaneously. Low thyroid hormone levels, elevated serum TSH values and high titers of antithyroid antibodies (ATA) were consistent with primary hypothyroidism. The diagnosis of...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348331

    authors: Roosens B,Maes E,Van Steirteghem A,Vanhaelst L

    更新日期:1982-07-01 00:00:00

  • Effect of a synthetic pineal tetrapeptide (Ala-Glu-Asp-GLy) on melatonin secretion by the pineal gland of young and old rats.

    abstract::The pineal gland contains many peptides known to be implicated in melatonin production. We examined the effects of a synthetic pineal tetrapeptide Ala-Glu-Asp-Gly on melatonin secretion by the pineal gland. The tetrapeptide effects on pineal gland melatonin secretion were studied in young (9 weeks) and old (27 months)...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345159

    authors: Djeridane Y,Khavinson VKh,Anisimov VN,Touitou Y

    更新日期:2003-03-01 00:00:00

  • Metastatic renal cell carcinoma to the pituitary gland presenting with hypopituitarism.

    abstract::A 57-year-old man with pituitary metastasis from renal cell carcinoma is reported. He underwent right nephrectomy and total pancreatectomy for renal cell carcinoma and its pancreatic metastasis, respectively. Imaging studies showed an intrasellar mass lesion. The examination revealed panhypopituitarism, diabetes insip...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03345815

    authors: Koshiyama H,Ohgaki K,Hida S,Takasu K,Yumitori K,Shimatsu A,Koh T

    更新日期:1992-10-01 00:00:00

  • An exception to the rule: ectopic ACTH production from functional neuroendocrine tissue in an ovarian dermoid cyst.

    abstract::Ectopic ACTH production accounts for 15% of Cushing's syndrome presentations and is characterized by the presence of an excess of ACTH precursors. However in the case presented here ectopic ACTH production was from functional pituitary tissue within an ovarian dermoid cyst. Endocrine investigations showed that the pro...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03343930

    authors: Watson J,Taylor M,Pampiglione J,Rasbridge S,Armitage M

    更新日期:2001-11-01 00:00:00

  • Premarin priming does not alter growth hormone release following exercise.

    abstract::We evaluated the usefulness of premarin priming on exercise induced growth hormone release and the value of combining several growth hormone screening agents in a large population of prepubertal children. Two hundred five short healthy prepubertal children growing below the 5th percentile in height were studied. One h...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346963

    authors: Lanes R,Lifshitz F,Sekaran C,Fort P,Recker B

    更新日期:1986-12-01 00:00:00

  • Multiple intracranial recurrent tumors with hyperprolactinemia combined with a parasellar malignant fibrous histiocytoma long after transfrontal surgery and irradiation to a pituitary adenoma.

    abstract::We herein describe a 40-year-old woman with hyperprolactinemia, an empty sella and two extrasellar intracranial recurrent tumors which were revealed 23 years after the first transfrontal craniotomy and 18 years after the second transfrontal surgery and irradiation to a provable prolactin-producing pituitary macroadeno...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03351046

    authors: Fujikawa M,Okamura K,Sato K,Shiratsuchi M,Yao T,Mizokami T,Fujishima M

    更新日期:2001-06-01 00:00:00

  • Clinical and genetic characteristics of familial hypercholesterolemia patients with type 2 diabetes.

    abstract:PURPOSE:Though type 2 diabetes mellitus (T2DM) is an important and independent risk factor for coronary artery disease (CAD) in the general population, the impact of T2DM on CAD in patients with familial hypercholesterolemia (FH) is less understood. Thus, the current study aimed to examine the features of FH patients w...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-018-0959-0

    authors: Sun D,Cao YX,You XD,Zhou BY,Li S,Guo YL,Zhang Y,Wu NQ,Zhu CG,Gao Y,Dong QT,Liu G,Dong Q,Li JJ

    更新日期:2019-05-01 00:00:00

  • Comparative proteomics study of freshly isolated, in vitro cultured, and proliferating islet preparation cells.

    abstract:BACKGROUND:In vitro islet expansion has recently drawn interest for its potential application in diabetes therapy, while how islet cells adapt to in vitro circumstances is not quite clear. AIM:Proteomics changes of cultivated islet cells under different conditions were examined in this study. MATERIAL/SUBJECTS AND ME...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/7275

    authors: Li G,Yang X,Zhang Y,Liu H,Zhang W,Shen Y,Fan W,Lu Z,Lu D

    更新日期:2011-12-01 00:00:00

  • Ectopic aldosteronoma associated to another adrenocortical adenoma in the adrenal gland of the same side.

    abstract::The occurrence of tumors originating from aberrant adrenocortical tissue in ectopic site is very rare. Up to now only two cases of ectopic aldosterone-producing adenoma have been described. We have observed another case of ectopic aldosteronoma, located in the retrocaval region, laterally to the body of the 12th thora...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349816

    authors: Mazza E,Papotti M,Durando R,Robecchi A,Camanni F

    更新日期:1995-11-01 00:00:00

  • The vitamin D receptor fokI start codon polymorphism and bone mineral density in male hypogonadotrophic hypogonadism.

    abstract::The genetic factors determining bone mineral density (BMD) are not well characterized. Many studies have investigated the relationship between the fokI polymorphism of vitamin D receptor (VDR) gene in diverse populations and gender, resulting in conflicting outcomes. Because peak bone mass in men is closely related to...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347571

    authors: Bolu SE,Orkunoglu Suer FE,Deniz F,Uckaya G,Imirzalioglu N,Kutlu M

    更新日期:2005-10-01 00:00:00

  • Remission of acromegaly after treatment withdrawal in patients controlled by cabergoline alone or in combination with octreotide: results from a multicenter study.

    abstract:PURPOSE:Remission of acromegaly has been reported after somatostatin analogs withdrawal, but not after withdrawal of combination therapy with cabergoline, and only in case reports of patients controlled by cabergoline alone. METHODS:To establish the remission rates (normal IGF-1 for age/sex: IGF-1 ≤ 1.00 xULN) after w...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s40618-016-0595-5

    authors: Casagrande A,Bronstein MD,Jallad RS,Mota JI,Tabet A,Abucham J

    更新日期:2017-05-01 00:00:00

  • Exercise-induced endocrine pathologies.

    abstract::There has been a substantial increase in women practicing sports over the past 30 yr. While exercise provides many health benefits, there appears to be a unique set of risks associated with intense exercise for the female athlete. The female athlete triad encompasses these risks, including amenorrhea, osteoporosis and...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03345238

    authors: Warren MP,Goodman LR

    更新日期:2003-09-01 00:00:00

  • Recombinant human thyroid-stimulating hormone (rhTSH): clinical development.

    abstract::Recombinant human thyroid-stimulating hormone (rhTSH) was developed to safely provide exogenous TSH stimulation in patients on thyroid hormone suppression therapy (THST), which is integral to long-term management of well-differentiated thyroid cancer. Such stimulation allows detection of thyroid remnant and neoplastic...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Incerti C

    更新日期:1999-01-01 00:00:00

  • Interaction of highly purified thyroid peroxidase with anti-microsomal antibodies in autoimmune thyroid diseases.

    abstract::Among the several antigens involved in autoimmune thyroid diseases, the microsomal antigen has been recently identified as the human thyroid peroxidase (TPO). The availability of highly purified TPO and anti-TPO monoclonal antibody (mAb) allowed us to study in more details anti-TPO autoimmune antibodies (aAb) and thei...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348084

    authors: Czarnocka B,Ruf J,Ferrand M,Lissitzky S,Carayon P

    更新日期:1986-04-01 00:00:00

  • Serum 25 hydroxyvitamin D in employees of a Middle Eastern university hospital.

    abstract:BACKGROUND:The Middle East registers the highest rate of vitamin D deficiency worldwide. In Lebanon, previous studies looked at this deficiency in schoolchildren, university students, young adults and postmenopausal women. However, no previous study was performed in hospital workers. The objective of our study was to e...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-014-0061-1

    authors: Gannagé-Yared MH,Helou E,Zaraket V,Abi Akl S,Antonios L,Moussalli ML,Wakim S

    更新日期:2014-06-01 00:00:00

  • The effect of methimazole on the immune system is unlikely to operate directly on T lymphocytes.

    abstract::It has been shown that the antithyroid drug methimazole (MMI) may affect B cells and possibly accessory cell function. In the present study we investigated in detail the effects of MMI on T cell in vitro proliferation. The following variables were evaluated: T cell proliferation following stimulation with phytohemaggl...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348606

    authors: Bagnasco M,Venuti D,Ciprandi G,Pesce G,Paolieri F,Canonica GW

    更新日期:1990-06-01 00:00:00

  • Antithyroid drug treatment for Graves' disease: baseline predictive models of relapse after treatment for a patient-tailored management.

    abstract:BACKGROUND:Antithyroid drugs (ATDs) are first-line treatment for Graves' hyperthyroidism worldwide, but relapses are frequent. The reliability of individual risk factors to predict at baseline subsequent relapse is poor. Predictive scores grouping single risk factors might help to select the best treatment (pharmacolog...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-018-0918-9

    authors: Masiello E,Veronesi G,Gallo D,Premoli P,Bianconi E,Rosetti S,Cusini C,Sabatino J,Ippolito S,Piantanida E,Tanda ML,Chiovato L,Wiersinga WM,Bartalena L

    更新日期:2018-12-01 00:00:00

  • Growth hormone and the metabolic syndrome.

    abstract::The association of several risk factors, obesity, dyslipoproteinemia, hepatic steatosis, insulin resistance and hypertension with Type 2 (non-insulin-dependent) diabetes mellitus and myocardial infarction has long been known and has been termed the "metabolic syndrome". In 1988 Reaven introduced syndrome X as the link...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Johannsson G,Bengtsson BA

    更新日期:1999-01-01 00:00:00

  • Bicuculline enhances the corticosterone secretion induced by lipopolysaccharide and interleukin-1 alpha in male rats.

    abstract::Lipopolysaccharide (LPS)-induced inflammatory stress activates the hypothalamus-pituitary-adrenal (HPA) function. Interleukin-I (IL-1) is one of the key factors during this event; however, the mechanisms mediating IL-1 stimulation of HPA axis are still unclear. The present study evaluated the possible involvement of g...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349841

    authors: Guo AL,Petraglia F,Nappi RE,Criscuolo M,Ficarra G,Salvestroni C,Genazzani AD,Trentini GP,Genazzani AR

    更新日期:1996-02-01 00:00:00

  • Effect of 4-phenylbutyrate and valproate on dominant mutations of WFS1 gene in Wolfram syndrome.

    abstract:PURPOSE:Wolfram syndrome (WS) is a rare disorder caused by mutations in WFS1 that is characterized by diabetes mellitus, optic atrophy, sensorineural deafness, diabetes insipidus, and neurodegeneration. This disease is usually inherited as an autosomal recessive trait, but an autosomal dominant form has been reported. ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-020-01228-2

    authors: Batjargal K,Tajima T,Jimbo EF,Yamagata T

    更新日期:2020-09-01 00:00:00

  • Impact of short-term treatment with benzodiazepines and imidazopyridines on glucose metabolism in healthy subjects.

    abstract:AIM:In the last years there has been a progressive reduction of the average duration of sleep and an increase in the incidence of sleep disturbances. At the same time, an increase of the incidence of the metabolic syndrome has been described, partly attributable to the progressive worsening of dietary habits and the in...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s40618-013-0016-y

    authors: Gramaglia E,Ramella Gigliardi V,Olivetti I,Tomelini M,Belcastro S,Calvi E,Dotta A,Ghigo E,Benso A,Broglio F

    更新日期:2014-02-01 00:00:00

  • Historical milestones in endocrinology.

    abstract::The 1865 volume of the "II Morgagni", one of the most important Italian medical journals of the 19th century, presented two important articles, milestones for further scientific studies in the field of sexual differentiation. One was the original description of the "ramified cells" of testicular tubules by E. Sertoli,...

    journal_title:Journal of endocrinological investigation

    pub_type: 历史文章,杂志文章

    doi:10.1007/BF03345329

    authors: Virdis R

    更新日期:2005-11-01 00:00:00

  • Association between biochemical control and comorbidities in patients with acromegaly: an Italian longitudinal retrospective chart review study.

    abstract:PURPOSE:Achieving biochemical control (normalization of insulin-like growth factor-1 [IGF-1] and growth hormone [GH]) is a key goal in acromegaly management. However, IGF-1 and GH fluctuate over time. The true potential impact of time-varying biochemical control status on comorbidities is unclear and relies on multiple...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-019-01138-y

    authors: Colao A,Grasso LFS,Di Cera M,Thompson-Leduc P,Cheng WY,Cheung HC,Duh MS,Neary MP,Pedroncelli AM,Maamari R,Pivonello R

    更新日期:2020-04-01 00:00:00

  • Abundant daily non-sedentary activity is associated with reduced prevalence of metabolic syndrome and insulin resistance.

    abstract:BACKGROUND:Non-exercise activity thermogenesis has recently drawn attention because of its potential to prevent weight gain. AIM:This study evaluated the relationships between the duration of daily non-sedentary activities and the prevalence of metabolic syndrome and insulin resistance (IR) in the Japanese population....

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/9066

    authors: Uemura H,Katsuura-Kamano S,Yamaguchi M,Nakamoto M,Hiyoshi M,Arisawa K

    更新日期:2013-12-01 00:00:00

  • Puerperal breast feeding does not stimulate circulating opioids in humans.

    abstract::ACTH, beta lipotropin (beta LPH), beta endorphin (beta EP), Prolactin (PRL) and Cortisol were measured in the first five days of puerperium at 9:00, before and 30 minutes after suckling, in 7 healthy lactating women. With the exception of PRL plasma levels which decline, although remaining at high concentrations durin...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350534

    authors: Genazzani AR,Facchinetti F,Parrini D,Petraglia F,La Rosa R,Puggioni R,D'Antona N

    更新日期:1982-11-01 00:00:00

  • Clinical and endocrine features and long-term outcome of Graves' disease in early childhood.

    abstract::Hyperthyroidism is rare in early childhood and most commonly caused by Graves' disease. We report 14 children (4 boys, 10 girls) aged 3.4-7.5 yr. At diagnosis, all patients had weight loss, hyperkinetic activity, tachycardia, difficulty sleeping, and poor concentration and 11 presented with proptosis. Four patients de...

    journal_title:Journal of endocrinological investigation

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF03346315

    authors: Bossowski AT,Reddy V,Perry LA,Johnston LB,Banerjee K,Blair JC,Savage MO

    更新日期:2007-05-01 00:00:00