Synthetic salmon calcitonin is not diabetogenic in patients with normal or impaired glucose metabolism.

abstract：PURPOSE:Primary hyperparathyroidism has deleterious effects on health and causes nephrolithiasis and osteoporosis. However, it remains unclear whether parathyroidectomy benefits kidney function among patients with primary hyperparathyroidism. METHODS:In this retrospective study, patients with primary hyperparathyroidi...

journal_title：Journal of endocrinological investigation

authors： Liang CC,Yeh HC,Lo YC,Chou CY,Yen TH,Tsai HC,Hsu SP,Kuo CC

更新日期：2020-07-29 00:00:00

abstract：BACKGROUND:Antithyroid drugs (ATDs) are first-line treatment for Graves' hyperthyroidism worldwide, but relapses are frequent. The reliability of individual risk factors to predict at baseline subsequent relapse is poor. Predictive scores grouping single risk factors might help to select the best treatment (pharmacolog...

journal_title：Journal of endocrinological investigation

authors： Masiello E,Veronesi G,Gallo D,Premoli P,Bianconi E,Rosetti S,Cusini C,Sabatino J,Ippolito S,Piantanida E,Tanda ML,Chiovato L,Wiersinga WM,Bartalena L

更新日期：2018-12-01 00:00:00

abstract：:The intravenous injection of calcium gluconate (0.11 mM/kg body weight) into conscious thyroidectomized pigs elicits a 30% rise in both ionized and total calcium concentrations of plasma, which return to basal levels within 180 min. The administration of calcitonin (2.5-10 MRC U/kg body weight) reduces this time to 30...

journal_title：Journal of endocrinological investigation

authors： Jaros GG,Van Hoorn-Hickman R,Maier H,Newman E

更新日期：1983-04-01 00:00:00

abstract：PURPOSE:Although a nation-wide salt iodization program on voluntary basis was implemented in 2005, many areas in our country are still characterized by mild iodine deficiency. Differently from the rest of Italy, an efficient program of iodine prophylaxis was implemented in 1981 in the Autonomous Province of Bolzano. Th...

journal_title：Journal of endocrinological investigation

authors： Olivieri A,Radetti G,Medda E,Italian Study Group for Congenital Hypothyroidism.

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Protein tyrosine phosphatase (PTP)- 1B, encoded by the PTPN1 gene, negatively regulates insulin signaling by dephosphorylating the phosphotyrosine residues of the insulin receptor kinase activation segment. Several rare single nucleotide polymorphisms (SNP) have been linked to diseases accompanying insulin r...

journal_title：Journal of endocrinological investigation

authors： Gu P,Jiang W,Du H,Shao J,Lu B,Wang J,Zou D

更新日期：2010-07-01 00:00:00

abstract：:Experimental data concerning the role of serotonin (5-HT) in the control of gonadotropins secretion remain controversial: different receptors subtypes should mediate the serotoninergic action. In the present work we analyzed in prepubertal and adult male rats the FSH and LH responses after administration of the follow...

journal_title：Journal of endocrinological investigation

authors： Pinilla L,Tena-Sempere M,Aguilar E

更新日期：1997-07-01 00:00:00

abstract：:Volume receptors are situated in many organs and are capable of modulating ADH secretion. We have evaluated the variation of plasma ADH concentration after an experimentally induced increase of cerebrospinal fluid (CSF) pressure (PCSF). The experiment was performed in controlled environmental conditions to avoid pain ...

journal_title：Journal of endocrinological investigation

authors： Satta A,Palomba D,Demontis MP,Varoni MV,Faedda R,Ginanni A,Anania V

更新日期：1996-07-01 00:00:00

abstract：:To investigate whether chronic endogenous hypercalcemia influences TSH and/or PRL release from pituitary thyrotrophs and lactotrophs in man, 10 patients with endogenous hypercalcemia, due either to cancer or to primary hyperparathyroidism, were injected with 25 micrograms TRH iv. The TSH and PRL responses were compare...

journal_title：Journal of endocrinological investigation

authors： Röjdmark S,Edström E,Nordlund M

更新日期：1984-12-01 00:00:00

abstract：:The effect of exogenous prednisone on serum thyrotropin (TSH), thyroxine (T4), and triiodothyronine (T3) concentrations was investigated in four patients with non-functioning thyroid glands receiving T4 replacement therapy. Orally administered prednisone, in a dose of 20 mg each day for nine days, resulted in a signif...

journal_title：Journal of endocrinological investigation

authors： Jensen J,Nolan G,Jubiz W

更新日期：1978-04-01 00:00:00

abstract：PURPOSE:Testosterone replacement therapy (TRT) is recommended for the treatment of most cases of male hypogonadism. Transdermal testosterone (T) gels are commonly used in clinical practice; however, there is little evidence concerning how to monitor dosage to bring and maintain serum T levels in the normal physiologic ...

journal_title：Journal of endocrinological investigation

authors： Sansone A,Sansone M,Selleri R,Schiavo A,Gianfrilli D,Pozza C,Zitzmann M,Lenzi A,Romanelli F

更新日期：2019-12-01 00:00:00

abstract：:We evaluated the effect of six-month treatment with growth hormone (GH) or low-dose oxandrolone in a group of boys with constitutional growth delay (CGD). Sixteen boys were randomly assigned to two treatment groups. Group 1 received GH (0.6 U/kg/week sc 5-6 times/week) and Group 2 received oxandrolone (0.07 mg/kg po)....

journal_title：Journal of endocrinological investigation

authors： Loche S,Pintor C,Cambiaso P,Lampis A,Carta D,Corda R,Cappa M

更新日期：1991-10-01 00:00:00

abstract：AIM:We investigated inpatients with and without Type 2 diabetes mellitus, aged over 60 yr, to compare their vitamin D status and calcium homeostatic parameters. MATERIALS AND METHODS:We studied 140 patients consecutively admitted to our Internal Medicine Unit during the year 2010 (61 from November to April, 79 from Ma...

journal_title：Journal of endocrinological investigation

authors： Carnevale V,Inglese M,Annese MA,De Matthaeis A,Santini SA,Frusciante V,Fontana A,Copetti M,Pellegrini F,D'Amico G

更新日期：2012-10-01 00:00:00

abstract：:We investigated ACTH and cortisol responses after ovine CRF injection (1 microgram/kg one bolus) in a group of 11 drug-free patients suffering from major depression. When compared to sex- and age-matched normal controls, our depressed patients showed: Higher ACTH basal values (p less than 0.002); higher cortisol basal...

journal_title：Journal of endocrinological investigation

authors： Nerozzi D,Bersani G,Melia E,Magnani A,Antonozzi I,Frajese G

更新日期：1988-11-01 00:00:00

abstract：:The calcitonin (CT) concentration has been determined in the serum of 17 patients with different pituitary diseases. More or less elevated levels were found in 7 of them. No definite correlation has been observed between the immunoreactive CT and the different pituitary hormones. ...

journal_title：Journal of endocrinological investigation

authors： Ziliotto D,Luisetto G,Cecchini M,Gastaldo M,Francia G,Padovan L,Heynen G

更新日期：1980-01-01 00:00:00

abstract：:During a systematic study of women with idiopathic galactorrhea, we observed several patients with normal random serum prolactin (PRL) levels and normal menses, but abnormal sellar tomograms characteristic of a pituitary adenoma. To test the hypothesis that these women might have intermittent PRL hypersecretion, we st...

journal_title：Journal of endocrinological investigation

authors： Kapcala LP,Molitch ME,Arno J,King LW,Reichlin S,Wolpert SM

更新日期：1984-10-01 00:00:00

abstract：AIM:This 3-month study compared the effect on overall glycemic control of adding biphasic insulin aspart 30 (BIAsp30) and premixed human insulin 30/70 (BHI30) to metformin (met) in insulin-naïve, obese patients (30 males/20 females) with Type 2 diabetes (T2DM). MATERIAL/SUBJECTS: At baseline, patients had a mean age of...

journal_title：Journal of endocrinological investigation

authors： Velojic-Golubovic M,Mikic D,Pesic M,Dimic D,Radenkovic S,Antic S

更新日期：2009-01-01 00:00:00

abstract：:The effect of right- and left-sided intra-amygdaloid injection of kainic acid on the hypothalamo-hypophyseal-testicular axis was studied in rats. Both right- and left-sided injection of the neurotoxin into the amygdala resulted in a significant decrease in basal testosterone secretion in vitro of both testes and in se...

journal_title：Journal of endocrinological investigation

authors： Banczerowski P,Csaba Z,Csernus V,Gerendai I

更新日期：2003-05-01 00:00:00

abstract：:The effects of estriol on serum prolactin (PRL) and LH levels, on the pituitary response to TRH and LHRH and on the synthesis and release of PRL from the anterior pituitary gland were investigated in female rats. The increase of serum PRL levels after estradiol administration was found to be associated with an increas...

journal_title：Journal of endocrinological investigation

authors： Diaz MC,Seilicovich A,Duvilanski BH,Siseles N,Lasaga M,Debeljuk L

更新日期：1989-01-01 00:00:00

abstract：:The occurrence of metabolic bone disease in patients with renal dysfunction is due to the key role played by the kidney in regulating calcium-phosphate metabolism. The incidence of hip fractures in end-stage renal disease is 3- to 4-fold higher than the general population, while poor data about vertebral fractures sho...

journal_title：Journal of endocrinological investigation

authors： Fusaro M,D'Angelo A,Scalzo G,Gallieni M,Giannini S,Guglielmi G

更新日期：2010-05-01 00:00:00

abstract：:A comparison of peripheral patterns of androstenedione (A), 17 beta-estradiol (E2) and progesterone (P) is reported in ten infertile women during HMG-HCG induction of ovulation, in order to assess the site of ovarian secretion of plasma A and the possible influence on conception. Evidence for both the follicular and l...

journal_title：Journal of endocrinological investigation

authors： Scirpa P,Mango D,Montemurro A,Battaglia F,Cantafio L

更新日期：1984-08-01 00:00:00

abstract：:Thyrotropin binding characteristics and adenylate cyclase (AC) activity of thyroid plasma membranes were studied in 52 tissues from normal and diseased human thyroids. Data from normal glands, Graves' goiters, non toxic multinodular goiters and nodular and perinodular tissue of toxic nodular goiters show the same basa...

journal_title：Journal of endocrinological investigation

authors： Carayon P,Guibout M,Lissitzky S

更新日期：1978-10-01 00:00:00

abstract：:Eight-year follow-up evaluation and analysis of factors related to postoperative thyroid dysfunction were made in 216 patients with Graves' disease treated by subtotal thyroidectomy. The postoperative status of thyroid function were as follows according to hypersensitive TSH level: 65 patients (30.1%) were euthyroid, ...

journal_title：Journal of endocrinological investigation

authors： Sugino K,Mimura T,Toshima K,Iwabuchi H,Kitamura Y,Kawano M,Ozaki O,Ito K

更新日期：1993-03-01 00:00:00

abstract：:Recently, bromocriptine has been successfully introduced as medical therapy for the pituitary hypersecreting syndromes of hyperprolactinemia and acromegaly. Subsequently, an inhibitory effect on ACTH secretion was reported using bromocriptine in Cushing's disease. While most studies have focused on the acute response ...

journal_title：Journal of endocrinological investigation

authors： Kapcala LP,Jackson IM

更新日期：1982-03-01 00:00:00

abstract：:Forty-three euthyroid patients with a single, solid, nonfunctioning thyroid nodule were submitted to fine needle aspiration biopsy and serum thyroglobulin (Tg) was measured before and after (48h) 10 U of bovine TSH. Twenty-two normal subjects were also submitted to the bTSH test. Patients with nonfunctioning nodules w...

journal_title：Journal of endocrinological investigation

authors： Leite Z,Carneiro P,Halpern A,Medeiros-Neto G

更新日期：1987-06-01 00:00:00

abstract：:The association of several risk factors, obesity, dyslipoproteinemia, hepatic steatosis, insulin resistance and hypertension with Type 2 (non-insulin-dependent) diabetes mellitus and myocardial infarction has long been known and has been termed the "metabolic syndrome". In 1988 Reaven introduced syndrome X as the link...

journal_title：Journal of endocrinological investigation

authors： Johannsson G,Bengtsson BA

更新日期：1999-01-01 00:00:00

abstract：:The mechanisms underlying the antifertility effects of hyperprolactinemia have yet to be established in an appropriate experimental model. Hyperprolactinemia is a known side effect of fluphenazine, a broad spectrum, long-acting phenothiazine known to be dopamine type-D2 receptor antagonist. In our earlier study in adu...

journal_title：Journal of endocrinological investigation

authors： Aleem M,Choudhari J,Padwal V,Balasinor N,Parte P,Gill-Sharma MK

更新日期：2005-01-01 00:00:00

abstract：:Among the several antigens involved in autoimmune thyroid diseases, the microsomal antigen has been recently identified as the human thyroid peroxidase (TPO). The availability of highly purified TPO and anti-TPO monoclonal antibody (mAb) allowed us to study in more details anti-TPO autoimmune antibodies (aAb) and thei...

journal_title：Journal of endocrinological investigation

authors： Czarnocka B,Ruf J,Ferrand M,Lissitzky S,Carayon P

更新日期：1986-04-01 00:00:00

abstract：:This is a brief case report on a four-month-old girl who was admitted for failure to thrive and moderate dehydration. On admission she was mildly dehydrated and undernourished but with otherwise normal physical findings. Laboratory investigation disclosed mild but constant hyponatremia and hyperkalemia, very high plas...

journal_title：Journal of endocrinological investigation

authors： Mardesić D,Sarnavka V,Dumić M,Stipić V

更新日期：1992-03-01 00:00:00

abstract：PURPOSE:Growth hormone deficiency (GHD) is the most common endocrine late effect observed in childhood cancer survivors (CCS) previously submitted to cranial irradiation. Radiation therapy can also increase the risk of second neoplasms (SNs). Since in previous studies GH replacement therapy was associated with increase...

journal_title：Journal of endocrinological investigation

authors： Brignardello E,Felicetti F,Castiglione A,Fortunati N,Matarazzo P,Biasin E,Sacerdote C,Ricardi U,Fagioli F,Corrias A,Arvat E

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:Polycystic ovary syndrome (PCOS) is a common heterogeneous endocrine disorder companied with neuroendocrine and metabolic disorders. Gut microbiota has been implicated to play a key role in metabolic diseases and the production of neurotransmitters. Previous studies have reported the alterations in the gut micr...

journal_title：Journal of endocrinological investigation

authors： Liang Z,Di N,Li L,Yang D

更新日期：2021-01-02 00:00:00