Iodine deficiency and goiter prevalence in Turkey after mandatory iodization.

Abstract:

OBJECTIVE:The determination of (a) iodine deficiency, and (b) the relation between the iodized salt consumption in the Isparta province of Turkey. METHODS:Five hundred students between 6-11 yr of age were evaluated. With a questionnaire, the subjects were asked whether they were using iodine-containing salt or not. After their body weight and height were measured, thyroid glands were examined with palpation, thyroid volumes were determined with ultrasonography (USG), and urinary iodine concentration was analyzed. RESULTS:The median urinary iodine concentration (UIC) of children was 7.00 microg/dl. This value reveals that Isparta is a region with mild iodine deficiency. The total goiter prevalence was 30.4% with palpation and 26% with USG. The goiter prevalence by ultrasonography was 14.2% for the urban and 36.2% for the rural areas. This difference was statistically significant (p<0.05). The rate of total iodized salt consumption was 68%, which was not a satisfactory level. The consumption of iodized salt in the urban areas was significantly higher than that in rural areas (74 vs 62%, p<0.05). The median UIC value was 10.00 microg/dl in urban areas compared to 5.00 microg/dl in rural areas. CONCLUSIONS:Our results indicate that although Isparta is a region with mild iodine deficiency, goiter prevalence remains a serious problem.

journal_name

J Endocrinol Invest

authors

Cetin H,Kisioglu AN,Gursoy A,Bilaloglu E,Ayata A

doi

10.1007/BF03344181

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

714-8

issue

8

eissn

0391-4097

issn

1720-8386

pii

2033

journal_volume

29

pub_type

杂志文章
  • Asymmetric dimethylarginine levels in thyroid diseases.

    abstract::Thyroid diseases may lead to endothelial dysfunction; however, the mechanism underlying the endothelial dysfunction in thyroid disease is not clear yet. Asymmetric dimethylarginine (ADMA), a novel inhibitor of endothelial nitric oxide synthase (eNOS), blocks nitric oxide (NO) synthesis from L-arginine. Symmetric dimet...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347423

    authors: Arikan E,Karadag CH,Guldiken S

    更新日期:2007-03-01 00:00:00

  • A case of hypersensitivity to thyroid hormones with normally functioning thyroid gland and increased nuclear triiodothyronine receptors.

    abstract::A 52-year-old male presented himself with tachycardia crises which appeared first during childhood, increased in frequency without goiter or exophthalmos. Cardiac and adrenergic diseases were excluded. The thyroid function was normal regarding T4, free T4 and T3, TBG, radioiodine uptake, TSH and T3 suppressibility; ho...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349636

    authors: Jaffiol C,Baldet L,Torresani J,Bismuth J,Papachristou C

    更新日期:1990-11-01 00:00:00

  • Is elevated urotensin II level a predictor for increased cardiovascular risk in subjects with acromegaly?

    abstract:PURPOSE:Acromegaly is a rare disorder existed in the result of overproduction of growth hormone (GH). The disorder is associated with increased cardiovascular risk factors and metabolic abnormalities. Urotensin II (UII), a secreted vasoactive peptide hormone, belonging somatostatin superfamily, plays an essential role ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-018-0905-1

    authors: Demirpence M,Guler A,Yilmaz H,Sayin A,Pekcevik Y,Turkon H,Colak A,Ari EM,Aslanipour B,Kocabas GU,Calan M

    更新日期:2019-02-01 00:00:00

  • 25-Hydroxycholecalciferol as an antagonist of adverse corticosteroid effects on phosphate and calcium metabolism in man.

    abstract::The present study was performed in 30 patients who needed steroid therapy: courses of triamcinolone or DTM 8-15 given orally lasted 30 days. In 15 of these patients glucoactive corticosteroids were administered in combination with 5 micrograms/day of 25OH-vitamin D3 (25OHD3). 47Calcium oral test and 99mTc-MDP kinetics...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348448

    authors: Nuti R,Vattimo A,Turchetti V,Righi G

    更新日期:1984-10-01 00:00:00

  • Prevalence of hypopituitarism in patients with cerebrovascular diseases.

    abstract::Stroke is one of the main causes of death and disability in the adult population. Changes in pituitary hormone secretion may be observed during the acute phase of stroke, representing part of the adaptive response to injury. However, reduced pituitary hormone secretion, caused by pituitary and/or hypothalamus damage, ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Bondanelli M,Ambrosio MR,Zatelli MC,Basaglia N,Degli Uberti EC

    更新日期:2008-09-01 00:00:00

  • Effects of PCSK9 inhibitors on LDL cholesterol, cardiovascular morbidity and all-cause mortality: a systematic review and meta-analysis of randomized controlled trials.

    abstract:BACKGROUND AND AIMS:Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors determine a wide reduction of LDL cholesterol, greater than other lipid-lowering agents. The present meta-analysis is aimed at the assessment of PCSK9 inhibitors effect on LDL Cholesterol, cardiovascular morbidity and all-cause mortali...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,meta分析

    doi:10.1007/s40618-019-01019-4

    authors: Dicembrini I,Giannini S,Ragghianti B,Mannucci E,Monami M

    更新日期:2019-09-01 00:00:00

  • Factor analysis of metabolic syndrome components in severely obese girls and boys.

    abstract:AIMS AND METHODS:Factor analysis is a multivariate correlation technique frequently employed to characterise the aggregation of abnormalities underlying the metabolic syndrome (MS), but scarcely used in obese adolescents. Aim of the study was to investigate the clustering of anthropometric and metabolic variables relat...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346506

    authors: Lafortuna CL,Adorni F,Agosti F,De Col A,Zennaro R,Caranti D,Sartorio A

    更新日期:2009-06-01 00:00:00

  • Copeptin in the differential diagnosis of hypotonic polyuria.

    abstract:COPEPTIN:Copeptin is secreted in equimolar amount to Arginine Vasopressin (AVP) but can easily be measured with a sandwich immunoassay. Both peptides, copeptin and AVP, show a high correlation. Accordingly, copeptin mirrors the amount of AVP in the circulation and its measurement provides an attractive marker in the di...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/s40618-019-01087-6

    authors: Christ-Crain M,Fenske WK

    更新日期:2020-01-01 00:00:00

  • Effects of naloxone on adrenal cortex regulation in patients with primary aldosteronism.

    abstract::Excess production of proopiomelanocortin (POMC)-derived peptides with aldosterone-stimulating activity has been suggested to play a pathogenetic role in idiopathic hyperaldosteronism (IHA). To further investigate this issue, the opiate receptor antagonist naloxone was administered to 14 patients with primary aldostero...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350149

    authors: Fallo F,Boscaro M,Sonino N,Mantero F

    更新日期:1988-04-01 00:00:00

  • Graves' disease and Hashimoto's thyroiditis: effects of high doses of antithyroid drugs on thyroid autoantibody levels.

    abstract::We studied the effects of high doses of methimazole (MMI) or propylthiouracil (PTU) on thyroid-stimulating antibody (TSAb), antithyroid microsomal (MCHA) and antithyroglobulin (TGHA) levels in Graves' disease and Hashimoto's thyroiditis. Thirty Graves' hyperthyroid patients were treated for 14 +/- 8 months (mean +/- S...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348107

    authors: Romaldini JH,Werner MC,Rodrigues HF,Teixeira VL,Werner RS,Farah CS,Bromberg N

    更新日期:1986-06-01 00:00:00

  • Thyroid, hemostasis and thrombosis.

    abstract::The aim of this paper is to briefly review some practical aspects of the relationship between thyroid function and several disorders of the hemostatic system in terms of bleeding and thrombosis. Thrombocytopenia, acquired hemophilia, hypercoagulability, cardioembolism and other biochemical coagulative and fibrinolytic...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03345311

    authors: Marongiu F,Cauli C,Mariotti S

    更新日期:2004-12-01 00:00:00

  • Regulation of sodium/iodide symporter and lactoperoxidase expression in four human breast cancer cell lines.

    abstract:BACKGROUND:Agents capable of increasing radioiodine concentration by stimulating the sodium/iodide symporter (NIS) expression have been extensively investigated for the treatment of certain well-differentiated breast cancers. AIM:In this study, we analyzed the regulation of the NIS and lactoperoxidase (LPO) gene expre...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03346542

    authors: Sponziello M,Scipioni A,Durante C,Verrienti A,Maranghi M,Giacomelli L,Ferretti E,Celano M,Filetti S,Russo D

    更新日期:2010-01-01 00:00:00

  • Alterations of gut microbiota composition in post-finasteride patients: a pilot study.

    abstract:PURPOSE:Post-finasteride syndrome (PFS) has been reported in a subset of patients treated with finasteride (an inhibitor of the enzyme 5alpha-reductase) for androgenetic alopecia. These patients showed, despite the suspension of the treatment, a variety of persistent symptoms, like sexual dysfunction and cognitive and ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-020-01424-0

    authors: Borgo F,Macandog AD,Diviccaro S,Falvo E,Giatti S,Cavaletti G,Melcangi RC

    更新日期:2020-09-19 00:00:00

  • Extraprostatic complications of testosterone replacement therapy.

    abstract::Testosterone therapy has been reported to be useful in the treatment of hypogonadism and partial androgen deficiency of the aging male (PADAM) syndrome. Testosterone administration is needed in order to maintain secondary sexual characteristics, muscle mass, bone mineral density, cognitive function and sexual drive. N...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Volpi R,Coiro V,Chiodera P,Saccani-Jotti G,Delsignore R

    更新日期:2005-01-01 00:00:00

  • Influence of environmental iodine deficiency on neonatal thyroid screening results.

    abstract::During a multicentric pilot screening program for congenital hypothyroidism a comparison between the results obtained from Urbino, an area characterized by low iodine supply and endemic goiter, and Rome, a non-endemic area, has been made. The evaluation of neonatal urinary iodine excretion in the two areas showed sign...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350156

    authors: Carta Sorcini M,Diodato A,Fazzini C,Sabini G,Carta S,Grandolfo ME,Guidi M,Vasta M,Locatelli De Maestri J,Donati L

    更新日期:1988-04-01 00:00:00

  • The silent corticotropinoma: is clinical diagnosis possible?

    abstract::Up to now, the diagnosis of silent corticotroph cell pituitary adenomas has been made only on histopathological basis. In this paper we describe 6 women affected with pituitary adenomas, without evident clinical features of hypercortisolism, in whom retrospective data suggested the possibility of clinically diagnosing...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348769

    authors: Ambrosi B,Colombo P,Bochicchio D,Bassetti M,Masini B,Faglia G

    更新日期:1992-06-01 00:00:00

  • Use of low-dose radioiodine ablation for Graves' orbitopathy: results of a pilot, perspective study in a small series of patients.

    abstract:OBJECTIVE:Elimination of thyroid antigens by total thyroid ablation (TTA), namely, thyroidectomy followed by radioiodine, may be beneficial for Graves' Orbitopathy (GO). TTA is usually performed with a 131I dose of 30 mCi. In Italy, this dose must be followed by a 24-h protected hospitalization, with increase in the wa...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-017-0754-3

    authors: Leo M,Sabini E,Ionni I,Sframeli A,Mazzi B,Menconi F,Molinaro E,Bianchi F,Brozzi F,Santini P,Elisei R,Nardi M,Vitti P,Marcocci C,Marinò M

    更新日期:2018-03-01 00:00:00

  • Serum nesfatin-1 and leptin levels in non-obese girls with premature thelarche.

    abstract:AIM:We aimed to investigate serum nesfatin-1 level in girls with premature thelarche (PT) and its relationship with anthropometric parameters and leptin, which are involved in the initiation of pubertal process. SUBJECTS-METHODS:Non-obese girls who presented with the complaint of early (2-8 years) and isolated breast ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-015-0277-8

    authors: Çatlı G,Anık A,Küme T,Çalan ÖG,Dündar BN,Böber E,Abacı A

    更新日期:2015-08-01 00:00:00

  • Reduced serum thyroglobulin response to bovine TSH in malignant hypofunctioning solid thyroid nodules: comparison to benign nodular disease.

    abstract::Forty-three euthyroid patients with a single, solid, nonfunctioning thyroid nodule were submitted to fine needle aspiration biopsy and serum thyroglobulin (Tg) was measured before and after (48h) 10 U of bovine TSH. Twenty-two normal subjects were also submitted to the bTSH test. Patients with nonfunctioning nodules w...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348125

    authors: Leite Z,Carneiro P,Halpern A,Medeiros-Neto G

    更新日期:1987-06-01 00:00:00

  • Presence of metabolic risk factors in non-obese PCOS sisters: evidence of heritability of insulin resistance.

    abstract::This study was performed to determine whether phenotypically healthy sisters of women with polycystic ovary syndrome (PCOS) have evidence of insulin resistance. We studied 54 women: 17 with PCOS, 17 sisters of these probands and 20 control women with similar age, body mass index (BMI) and waist-to-hip ratio (WHR). The...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347535

    authors: Diamanti-Kandarakis E,Alexandraki K,Bergiele A,Kandarakis H,Mastorakos G,Aessopos A

    更新日期:2004-11-01 00:00:00

  • Simple radioimmunological assay of anti-alpha-galactosyl antibody (anti-Gal): application to autoimmune thyroid diseases and thyroid-associated ophthalmopathy.

    abstract::Two radioimmunological techniques for the measurement of anti-alpha-galactosyl (anti-Gal) antibodies were developed and we demonstrated that this antibody is present in the serum of most untreated patients with Graves' disease, thyroid-associated ophthalmopathy (TAO) and autoimmune thyroiditis. Thyrotropin-binding inh...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349806

    authors: Winand RJ,Winand-Devigne J,Cox C,Caulier C,Meurisse M

    更新日期:1995-11-01 00:00:00

  • Effects of opioid receptor blockade on luteinizing hormone (LH) pulses and interpulse LH concentrations in normal women during the early phase of the menstrual cycle.

    abstract::To determine the role of endogenous opioid peptides in regulating pulsatile luteinizing hormone (LH) release in the early follicular phase of the menstrual cycle of eumenorrheic women, we evaluated serum LH concentrations in blood collected every 10 min for 12 h in 27 women each studied during two menstrual cycles: (1...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03348799

    authors: Evans WS,Weltman JY,Johnson ML,Weltman A,Veldhuis JD,Rogol AD

    更新日期:1992-07-01 00:00:00

  • Cardiac structure and functions in patients with asymptomatic primary hyperparathyroidism.

    abstract:BACKGROUND:The data about cardiovascular (CV) changes in patients with asymptomatic primary hyperparathyroidism (PHPT) are scarce. AIM:The aim of this study is to compare cardiac structure and functions in patients with asymptomatic PHPT and controls by using tissue Doppler echocardiography. SUBJECTS AND METHODS:Thir...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/8961

    authors: Aktas Yılmaz B,Akyel A,Kan E,Ercin U,Tavil Y,Bilgihan A,Cakır N,Arslan M,Balos Toruner F

    更新日期:2013-11-01 00:00:00

  • Medical therapy of sexual dysfunction.

    abstract::The recent development of new medications for the treatment of the sexual dysfunction increased the possibility of improving the altered sexual performance. Although initially designed for the treatment of male sexual dysfunction, erectile dysfunction in particular, these substances have now been tested for the therap...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Spera G,Pili M,Gnessi L,Spera E,Mariani S

    更新日期:2003-01-01 00:00:00

  • Vitamin D supplementation: when and how?

    abstract::The multiple effects of vitamin D on skeletal and extra-skeletal tissues increased the attention of scientists and public to the possible relationship between hypovitaminosis D and a variety of acute and chronic diseases. However, several points are still largely debated. In particular, the definition of optimal vitam...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/s40618-014-0071-z

    authors: Romagnoli E,Carnevale V,Biondi P,Minisola S

    更新日期:2014-07-01 00:00:00

  • Maternal nutrition, fetal weight, body composition and disease in later life.

    abstract::Nutritional and hormonal milieu in utero affect fetal growth. Both parties involved have an independent chance, for the occurrence of a developmental error at any stage of their constant developing system. Studies suggest that pregnancy outcome is associated with fetal demand for nutrients and the materno-placental ca...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03345248

    authors: Zadik Z

    更新日期:2003-09-01 00:00:00

  • New achievement and novel therapeutic applications of PDE5 inhibithors in older males.

    abstract::Erectile dysfunction (ED) increases in prevalence and severity because of aging processes and related organic, iatrogenic and social problems. Decline of testosterone (T) levels is observed with age and also in illnesses with a common basis of endothelial damage. The T deficiency may lead to decreased energy, mood dep...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Frajese GV,Pozzi F

    更新日期:2005-01-01 00:00:00

  • Therapeutic effects of obeticholic acid (OCA) treatment in a bleomycin-induced pulmonary fibrosis rat model.

    abstract:PURPOSE:We recently demonstrated a protective effect of the farnesoid X receptor agonist obeticholic acid (OCA) in rat models of bleomycin-induced pulmonary fibrosis (PF). Aim of the present study was to investigate whether the positive effects of OCA treatment are apparent also on ongoing bleomycin-induced PF, i.e., a...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-018-0913-1

    authors: Comeglio P,Filippi S,Sarchielli E,Morelli A,Cellai I,Corno C,Pini A,Adorini L,Vannelli GB,Maggi M,Vignozzi L

    更新日期:2019-03-01 00:00:00

  • Changes of circulating thyroid autoantibody levels during and after the therapy with methimazole in patients with Graves' disease.

    abstract::The changes occurring in the levels of circulating thyroid microsomal antibody (M-Ab) and antithyroglobulin antibody (Tg-Ab) during antithyroid drug therapy were studied in 32 patients receiving methimazole for Graves' disease. M-Ab was determined by competitive binding radioassay and Tg-Ab by a sandwich radiometric m...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03350476

    authors: Marcocci C,Chiovato L,Mariotti S,Pinchera A

    更新日期:1982-01-01 00:00:00

  • Follow-up evaluation of patients with Graves' disease treated by subtotal thyroidectomy and risk factor analysis for post-operative thyroid dysfunction.

    abstract::Eight-year follow-up evaluation and analysis of factors related to postoperative thyroid dysfunction were made in 216 patients with Graves' disease treated by subtotal thyroidectomy. The postoperative status of thyroid function were as follows according to hypersensitive TSH level: 65 patients (30.1%) were euthyroid, ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03344945

    authors: Sugino K,Mimura T,Toshima K,Iwabuchi H,Kitamura Y,Kawano M,Ozaki O,Ito K

    更新日期:1993-03-01 00:00:00