Malignant pancreatic oncocytoma. An unusual cause of organic hypoglycemia.

abstract：PURPOSE:In our previous study, we introduced a rat model of polycystic ovary syndrome (PCOS) induced by prenatal exposure to a single dose of testosterone on embryonic day 20. In the current study, we aimed to investigate whether prenatal exposure to a single dose of testosterone could also induce metabolic disturbance...

journal_title：Journal of endocrinological investigation

authors： Noroozzadeh M,Ramezani Tehrani F,Sedaghat K,Godini A,Azizi F

更新日期：2015-05-01 00:00:00

abstract：:The occurrence of a genetic background in the etiology of polycystic ovarian syndrome (PCOS) represents the rational basis to postulate the existence of a male PCOS equivalent. Hormonal and metabolic abnormalities have been described in male relatives of women with PCOS. These males also have a higher prevalence of ea...

journal_title：Journal of endocrinological investigation

authors： Cannarella R,Condorelli RA,Mongioì LM,La Vignera S,Calogero AE

更新日期：2018-01-01 00:00:00

abstract：:Prolactin, growth hormone and thyroid stimulating hormone responses to thyrotropin releasing hormone (TRH) and metoclopramide were determined in 12 alcoholic men with biopsy proven liver disease and were compared to those of 8 age matched normal controls. All subjects were challenged with TRH (400 micrograms) and meto...

journal_title：Journal of endocrinological investigation

authors： Van Thiel DH,Gavaler JS,Sanghvi A

更新日期：1982-09-01 00:00:00

abstract：:The in vivo suppressive effect of glucose and insulin on plasma free fatty acid concentrations was investigated in obese subjects with (n = 6) and without (n = 6) Type 2 (non-insulin-dependent) diabetes mellitus during a 4h-hyperglycemic glucose clamp (about 11.2 mmol/l). Somatostatin was infused (250 micrograms/h) du...

journal_title：Journal of endocrinological investigation

authors： Zancanaro C,Cigolini M,Bonora E,Moghetti P,Querena M,Muggeo M

更新日期：1990-01-01 00:00:00

abstract：:Monolayer cultures of medullary thyroid carcinoma (MTC) cells were prepared from 5 patients with familial and 4 with sporadic MTC. Basal calcitonin (CT) release decreased rapidly during 17 days in culture. Addition of extra calcium (2 mmol/l) or dibutyryl cyclic AMP (dBcAMP, 3 mmol/l) increased CT release in all inves...

journal_title：Journal of endocrinological investigation

authors： Oosterom R,Verleun T,Bruining HA,Hackeng WH,Lamberts SW

更新日期：1987-04-01 00:00:00

abstract：COPEPTIN:Copeptin is secreted in equimolar amount to Arginine Vasopressin (AVP) but can easily be measured with a sandwich immunoassay. Both peptides, copeptin and AVP, show a high correlation. Accordingly, copeptin mirrors the amount of AVP in the circulation and its measurement provides an attractive marker in the di...

journal_title：Journal of endocrinological investigation

authors： Christ-Crain M,Fenske WK

更新日期：2020-01-01 00:00:00

abstract：:Leptin may be a possible trigger for puberty. In normal males, it has been shown that leptin increases from the pre-pubertal to the early pubertal stage, and then declines in the late pubertal stage. We examined leptin levels in six male adolescents (mean age 16.3+/-0.6 yr; range 14.2-17.6 yr) with delayed puberty (co...

journal_title：Journal of endocrinological investigation

authors： Giusti M,Guido R,Valenti S,Giordano G

更新日期：1999-01-01 00:00:00

abstract：:Pheochromocytoma (PHEO) occasionally associates with pathological lesions of the adrenal cortex. In most of them, ectopic adrenocorticotropic hormone (ACTH) produced by PHEO resulted in bilateral adrenocortical hyperplasia. The coexistence of PHEO and pre-clinical Cushing's syndrome (PCS) of the same adrenal gland has...

journal_title：Journal of endocrinological investigation

authors： Erem C,Hacihasanoglu A,Ersöz HO,Reis AK,Calik A,Ukinç K,Koçak M

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:In the last decades, a higher incidence of congenital hypothyroidism (CH) has been recorded in Italy (1:1940) and worldwide, mainly due to the shift to lower screening TSH cutoffs. Although CH can also be caused by dysgenetic defects, most CH cases have recently been found to be more frequently associated wi...

journal_title：Journal of endocrinological investigation

authors： Vigone MC,Di Frenna M,Weber G

更新日期：2015-08-01 00:00:00

abstract：:Thyroid-stimulating antibody (TSAb) activity and the TSH-binding inhibitory immunoglobulin (TBII) index were assessed in 158 patients with Graves' disease who had been treated with 131I 6-14 years earlier. Twenty-one patients (13%) were still hyperthyroid, 45 (28%) were euthyroid, 44 (28%) were subclinically hypothyro...

journal_title：Journal of endocrinological investigation

authors： Yoshida K,Aizawa Y,Kaise N,Fukazawa H,Kiso Y,Sayama N,Mori K,Hori H,Abe K

更新日期：1996-11-01 00:00:00

abstract：:Several in vivo experimental and clinical studies suggest that the production of thymic hormones, such as thymulin (Zn-FTS), is modulated by thyroid hormones. It was not determined in these studies, however whether such modulation is exerted directly on the thymic epithelial cells which synthesize and secrete thymic h...

journal_title：Journal of endocrinological investigation

authors： Mocchegiani E,Amadio L,Fabris N

更新日期：1990-02-01 00:00:00

abstract：:Iodine balance during pregnancy and lactation was investigated by measuring iodine concentration in the urine of 11 pregnant women, born and living in a moderately iodine deficient endemic goiter area in Northeastern Sicily, collected during the last week of pregnancy, and between the 5th and 7th day after delivery, a...

journal_title：Journal of endocrinological investigation

authors： Vermiglio F,Lo Presti VP,Finocchiaro MD,Battiato S,Grasso L,Ardita FV,Mancuso A,Trimarchi F

更新日期：1992-02-01 00:00:00

abstract：PURPOSE:PATRO adults is an ongoing, multicenter, observational, post-marketing surveillance study aimed at investigating the long-term safety (primary endpoint) and effectiveness (secondary endpoint) of the recombinant human growth hormone (rhGH) Omnitrope® during routine clinical practice. This report describes data f...

journal_title：Journal of endocrinological investigation

authors： Arosio M,Arnaldi G,Gasco V,Giavoli C,Puxeddu E,Vettor R,Ambrosio MR,Gallinari P,Zouater H,Fedeli P,Ferone D

更新日期：2021-02-01 00:00:00

abstract：:Ectopic ACTH production accounts for 15% of Cushing's syndrome presentations and is characterized by the presence of an excess of ACTH precursors. However in the case presented here ectopic ACTH production was from functional pituitary tissue within an ovarian dermoid cyst. Endocrine investigations showed that the pro...

journal_title：Journal of endocrinological investigation

authors： Watson J,Taylor M,Pampiglione J,Rasbridge S,Armitage M

更新日期：2001-11-01 00:00:00

abstract：AIM:This 3-month study compared the effect on overall glycemic control of adding biphasic insulin aspart 30 (BIAsp30) and premixed human insulin 30/70 (BHI30) to metformin (met) in insulin-naïve, obese patients (30 males/20 females) with Type 2 diabetes (T2DM). MATERIAL/SUBJECTS: At baseline, patients had a mean age of...

journal_title：Journal of endocrinological investigation

authors： Velojic-Golubovic M,Mikic D,Pesic M,Dimic D,Radenkovic S,Antic S

更新日期：2009-01-01 00:00:00

abstract：:The long arm of the Y chromosome contains genes mapped in loci involved in male infertility, short stature and gonadoblastoma. However, many of these genes have not been fully characterized, and are not currently investigated in patients affected by such diseases. We report a study aimed to the genomic characterizatio...

journal_title：Journal of endocrinological investigation

authors： Stuppia L,Gatta V,Fogh I,Gaspari AR,Grande R,Morizio E,Fantasia D,Pizzuti A,Calabrese G,Palka G

更新日期：2000-11-01 00:00:00

abstract：:Obesity is associated with a number of serious diseases and with a degree of motor disability, but the extent of the risk and functional derangement within the obese population is not yet completely defined. The study aims to evaluate the combined effect of degree of adiposity, body fat distribution and age on selecte...

journal_title：Journal of endocrinological investigation

authors： Lafortuna CL,Agosti F,Proietti M,Adorni F,Sartorio A

更新日期：2006-11-01 00:00:00

abstract：:Cortistatin (CST), a 17-amino acid peptide partially homologous to somatostatin (SRIF), has been originally isolated from the cerebral cortex and recently found in monocytes and macrophages of the immune system. CST binds all 5 SRIF receptors, as well the GH secretagogue (GHS)/ghrelin receptors. CST exerts sleep promo...

journal_title：Journal of endocrinological investigation

authors： Papotti M,Tarabra E,Allia E,Bozzalla-Cassione F,Broglio F,Deghenghi R,Ghigo E,Muccioli G

更新日期：2003-08-01 00:00:00

abstract：:The occurrence of metabolic bone disease in patients with renal dysfunction is due to the key role played by the kidney in regulating calcium-phosphate metabolism. The incidence of hip fractures in end-stage renal disease is 3- to 4-fold higher than the general population, while poor data about vertebral fractures sho...

journal_title：Journal of endocrinological investigation

authors： Fusaro M,D'Angelo A,Scalzo G,Gallieni M,Giannini S,Guglielmi G

更新日期：2010-05-01 00:00:00

abstract：:Fifty-seven (35.6%) of 160 patients with papillary thyroid carcinoma had lymph node metastases at the primary treatment. Children and adolescents were most frequently affected (69.2%), followed by the age group of 21-40-year olds (38.8%). Those older than 40 had the lowest incidence of lymph node metastases (29.6%; p ...

journal_title：Journal of endocrinological investigation

authors： Ahuja S,Ernst H,Lenz K

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Glucagon-like peptide-1 (GLP-1) and its potent analog, exendin-4, are well known to inhibit β- cell apoptosis and promote β-cell proliferation. Meanwhile, cytokines, such as interleukin-1β (IL-1β), stimulate inducible nitric oxide synthase (iNOS) expression and nitric oxide overproduction leading to β-cell d...

journal_title：Journal of endocrinological investigation

authors： Liu XH,Wang YP,Wang LX,Chen Z,Liu XY,Liu LB

更新日期：2013-11-01 00:00:00

abstract：:The research suggests that adiponectin plays an important role in sensitizing insulin action. It is interesting to find that the lower levels of adiponectin exist in the plasma of obese and Type 2 diabetes subjects and in the adipose tissue of obese, db/db mice, and insulin-resistant individuals. However, the underlyi...

journal_title：Journal of endocrinological investigation

authors： Sun S,Liu Y,Lu J,Omar A,Sun S,Bi Y,Wang C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Neonatal hypothyroidism has serious effects on growth, development, and metabolism. AIM:This study aims to investigate the effects of the neonatal hypothyroidism on carbohydrate metabolism, islet insulin secretion and morphology of the pancreatic islets in adult male offspring. MATERIALS/SUBJECTS AND METHO...

journal_title：Journal of endocrinological investigation

authors： Farahani H,Ghasemi A,Roghani M,Zahediasl S

更新日期：2013-01-01 00:00:00

abstract：:This study examined the association of depression, anxiety, and stress with Type 2 diabetes (T2DM) in Bahrain, an island-country with a very high prevalence of T2DM. This was a cross-sectional study involving administering Depression Anxiety Stress Scales (DASS)-21 structured depression, anxiety, and stress scale to 1...

journal_title：Journal of endocrinological investigation

authors： Almawi W,Tamim H,Al-Sayed N,Arekat MR,Al-Khateeb GM,Baqer A,Tutanji H,Kamel C

更新日期：2008-11-01 00:00:00

abstract：:The diagnosis of growth hormone (GH) deficiency (GHD) is currently based on failure to increase plasma GH levels to an arbitrary cutoff point of 7 or 10 micrograms/l in response to two provocative stimuli. False negative responses to these tests, however, frequently occur thus reducing their diagnostic reliability. Th...

journal_title：Journal of endocrinological investigation

authors： Ghigo E,Imperiale E,Boffano GM,Mazza E,Bellone J,Arvat E,Procopio M,Goffi S,Barreca A,Chiabotto P

更新日期：1990-04-01 00:00:00

abstract：:Many hirsute women may present a form of functional ovarian hyperandrogenism (FOH), since they show an exaggerated 17-hydroxyprogesterone (17-OHP) response to GnRH agonists administration. As the failure of dexamethasone to reduce testosterone levels may be indicative of an ovarian source of androgen secretion, we eva...

journal_title：Journal of endocrinological investigation

authors： Re T,Barbetta L,Dall'Asta C,Faglia G,Ambrosi B

更新日期：2002-01-01 00:00:00

abstract：:Plasma levels and 24-h urinary excretion of cyclic AMP and cyclic GMP were measured in 18 patients with hyperthyroidism, 7 patients with hypothyroidism and 25 normal subjects. Mean plasma and urinary levels of both cyclic AMP and cyclic GMP were significantly positive correlations between the serum thyroid hormone lev...

journal_title：Journal of endocrinological investigation

authors： Peracchi M,Bamonti-Catena F,Lombardi L,Reschini E,Toschi V,Maiolo AT,Polli EE

更新日期：1983-06-01 00:00:00

abstract：:Anorexia nervosa (AN) is a complex mental disorder presenting psychiatric and physical symptoms. Literature recognizes the role of several factors in the pathogenesis of this disorder, according to the biopsychosocial model. Many mechanisms are still partly unclear. Endocrine and metabolic alterations usually occur in...

journal_title：Journal of endocrinological investigation

authors： Abbate Daga G,Gianotti L,Mondelli V,Quartesan R,Fassino S

更新日期：2004-11-01 00:00:00

abstract：:The 24-h profiles of plasma cortisol (F), 11-beta-hydroxyandrostenedione (11OHAD), androstenedione (AD), dehydroisoandrosterone (DHEA) and testosterone (T) were obtained simultaneously in 11 normal males sampled at 15-min intervals. The data were submitted to a detailed quantitative analysis including the estimation o...

journal_title：Journal of endocrinological investigation

authors： Lejeune-Lenain C,Van Cauter E,Désir D,Beyloos M,Franckson JR

更新日期：1987-06-01 00:00:00

abstract：:The aim of acromegaly treatment is to control the disease by suppressing GH hyperactivity and reducing the size or impeding the growth of the pituitary GH secreting mass. Over recent years, many studies have emphasized the role of SS analogs in the treatment of acromegaly. In fact, SS analogs have been demonstrated to...

journal_title：Journal of endocrinological investigation

authors： Gola M,Bonadonna S,Mazziotti G,Amato G,Giustina A

更新日期：2006-01-01 00:00:00