Abstract:
:Ketoacidosis is a metabolic alteration caused by absolute or relative insulin deficiency and oversecretion of glucagon. Prompt diagnosis and rapid initiation of treatment are mandatory to avoid the complications and fatal outcome. Reduction of plasma glucose to levels within acceptable limits, block of ketogenesis, re-establishment of hydroelectrolytic balance, correction of alterations of acido-base status are the most important goals in DKA treatment. However, all the corrections should be made slowly and under continuous control. Altered parameters must slope off very gradually to prevent dangerous hazards.
journal_name
J Endocrinol Investjournal_title
Journal of endocrinological investigationauthors
Reitano Gsubject
Has Abstractpub_date
1989-01-01 00:00:00pages
105-8issue
8 Suppl 3eissn
0391-4097issn
1720-8386journal_volume
12pub_type
杂志文章abstract::The activities of total superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) enzymes were measured in cancerous and non-cancerous adjacent tissues from 15 patients with follicular thyroid cancer containing single nodule. SOD and GSH-Px activities were found lower but malondialdehyde levels hi...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03347868
更新日期:1996-05-01 00:00:00
abstract::Regulation of the hypothalamic-pituitary-thyroid (HPT) axis is dependent upon the secretion of thyrotropin-releasing hormone (TRH), a tripeptide originating in the hypothalamic paraventricular nucleus (PVN). These so-called hypophysiotropic neurons are under feedback inhibition by circulating levels of thyroid hormone...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章,评审
doi:
更新日期:2004-01-01 00:00:00
abstract::Formation of connective tissue is an essential step in the process of wound healing. After menopause an atrophy of connective tissues in skin, bone, and reproductive organs takes place. Using a dead-space wound healing model we measured collagen synthesis and deposition, and cell replication in the granulation tissue ...
journal_title:Journal of endocrinological investigation
pub_type: 临床试验,杂志文章
doi:10.1007/BF03349870
更新日期:1996-04-01 00:00:00
abstract:PURPOSE:This study aimed to investigate the interactive effect of polycystic ovary syndrome (PCOS) status and obesity status on the serum levels of adipokines. METHODS:In this comparative case-control cross-sectional study, 58 women with PCOS and 104 eumenorrheic non-hirsute women as the control group were recruited. ...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/s40618-017-0650-x
更新日期:2017-08-01 00:00:00
abstract::It is well accepted that mortality in acromegaly is increased because of cardiovascular and respiratory diseases while neoplastic complications account less to mortality. Amongst different cardiovascular complications the most frequent is biventricular hypertrophy, which occurs independently of hypertension and metabo...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00
abstract::The aim of acromegaly treatment is to control the disease by suppressing GH hyperactivity and reducing the size or impeding the growth of the pituitary GH secreting mass. Over recent years, many studies have emphasized the role of SS analogs in the treatment of acromegaly. In fact, SS analogs have been demonstrated to...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章,评审
doi:10.1007/BF03349183
更新日期:2006-01-01 00:00:00
abstract::Traumatic brain injury (TBI)-induced hypopituitarism remains a relevant medical problem, because it may affect a significant proportion of the population. In the last decade important studies have been published investigating pituitary dysfunction after TBI. Recently, a group of experts gathered and revisited the topi...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.3275/7805
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:Nonalcoholic fatty liver disease (NAFLD) is associated with various metabolic abnormalities that can increase the risk of an osteoporotic fracture. Across the few previous studies of the association between NAFLD and bone mineral density (BMD), the association was not consistent. We examined the association bet...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/s40618-016-0528-3
更新日期:2016-11-01 00:00:00
abstract::To analyze the inhibitory effect of hormone replacement therapy (HRT) on bone resorption, we measured urinary excretion of C-telopeptide (CTX) and N-telopeptide (NTX) of type I collagen as new markers of bone resorption and assessed their correlation with bone mineral density, in comparison with urinary pyridinoline (...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03347294
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Adipose tissue has emerged as an important endocrine regulator by secreting hormones referred to as adipokines. Recent studies showed that adipose tissue considerably responds to hypoxia. Although the impact of white adipose tissue on regulative processes is established, the importance of brown adipose tissu...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.3275/7964
更新日期:2012-05-01 00:00:00
abstract::It has been reported that adult obese subjects present a reduced growth hormone secretion. As no data are available in the pubertal period, which is characterized in lean subjects by an increased spontaneous growth hormone secretion, the growth hormone circadian concentration was studied in a group of 18 obese male su...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03350166
更新日期:1988-07-01 00:00:00
abstract::Erectile dysfunction (ED) has been defined by the National Institute of Health (NIH) as the inability to achieve and/or to maintain an erection for a sufficiently long period of time so as to permit satisfactory sexual intercourse. ED affects millions of men throughout the world and could have a negative influence on ...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章,评审
doi:10.1007/BF03350917
更新日期:2004-01-01 00:00:00
abstract::We have developed a sandwich-type enzyme immunoassay for human chorionic gonadotropin (hCG), in which antibody Fab'-beta-D-galactosidase complex and an antibody-immobilized silicone rubber solid phase were used. Despite the fact this assay system crossreacted about 40% with human luteinizing hormone (LH) that contains...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03349444
更新日期:1981-07-01 00:00:00
abstract::A technique has been developed with which it has been possible to quantify the output of a wide variety of agonists including catecholamines, glucocorticoids, mineralocorticoids, enkephalins and various peptides, from the adrenal gland in the conscious unrestrained calf; also to investigate responses to electrical sti...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03349647
更新日期:1990-12-01 00:00:00
abstract::Patients with simple exogenous obesity are characterized by increased B-endorphin (B-EP) plasma levels, despite normal ACTH and B-Lipotropin (B-LPH). To evaluate the origin of such an hyperendorphinemia, 42 obese patients were submitted to a short overnight dexamethasone suppression test (DST: 1 mg at 23:00 h). Blood ...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03350117
更新日期:1988-02-01 00:00:00
abstract:PURPOSE:In patients with obesity, micronutrient deficiencies have been reported both before and after bariatric surgery (BS). Obesity is a chronic pro-inflammatory status, and inflammation increases the risk of micronutrient malnutrition. Our objective was to assess in pre-BS patients the prevalence of micronutrient de...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/s40618-020-01439-7
更新日期:2020-10-07 00:00:00
abstract:PURPOSE:Primary hyperparathyroidism has deleterious effects on health and causes nephrolithiasis and osteoporosis. However, it remains unclear whether parathyroidectomy benefits kidney function among patients with primary hyperparathyroidism. METHODS:In this retrospective study, patients with primary hyperparathyroidi...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/s40618-020-01369-4
更新日期:2020-07-29 00:00:00
abstract::We investigated ACTH and cortisol responses after ovine CRF injection (1 microgram/kg one bolus) in a group of 11 drug-free patients suffering from major depression. When compared to sex- and age-matched normal controls, our depressed patients showed: Higher ACTH basal values (p less than 0.002); higher cortisol basal...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03350921
更新日期:1988-11-01 00:00:00
abstract::A 36-year-old non-pregnant woman presented with a four-month history of progressive visual deterioration and amenorrhea. The latest gestation was 6 years earlier. Hormonal study revealed central diabetes insipidus, hypopituitarism, and slightly increased prolactin level. Ophthalmologic examination showed bilateral hem...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03343842
更新日期:2001-03-01 00:00:00
abstract::Severe bleeding into the peritoneal cavity from a ruptured ovulatory follicle is a rare complication in women receiving anticoagulation therapy. A number of both surgical and non surgical methods have been proposed to solve this problem. We adopted a novel therapeutic approach in a 40-year old patient who presented wi...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03348998
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:Adipose tissue has been suggested to influence bone density and metabolism through the effect of some adipokines. However, whether adiponectin and visfatin may correlate with bone metabolism is still unclear. AIM:The aim of this study was to investigate the relationship of adiponectin and visfatin with bone...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03346703
更新日期:2011-01-01 00:00:00
abstract::N-Methyl-D-Aspartate(NMDA)-sensitive glutamate receptors, are critically involved in the induction of the learning process. Activation of NMDA receptors by glutamate lead to massive influx of extracellular Ca2+, with ensuing activation of a variety of Ca(2+)-dependent enzymes, including protein kinase C. This triggers...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03348959
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND:Mutations of the thyrotropin receptor (TSHR) and/or Gαs gene have been found in a number of, but not all, autonomously functioning thyroid nodules (AFTNs). Recently, in a 15-year-old girl with a hyperfunctioning papillary thyroid carcinoma, we found two somatic and germline single nucleotide polymorphisms (S...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/s40618-014-0081-x
更新日期:2014-07-01 00:00:00
abstract::Scavenger receptor A (SR-A) is the main receptor through which oxidized LDL (oxLDL) and advanced glycation end products get into the cells. The aim of the present study was to investigate the effect of an ACE inhibitor, perindopril, on the expression of SR-A in renal tubulointerstitium of diabetic rats. Diabetes was i...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.3275/7867
更新日期:2012-05-01 00:00:00
abstract::Thyrotropin binding characteristics and adenylate cyclase (AC) activity of thyroid plasma membranes were studied in 52 tissues from normal and diseased human thyroids. Data from normal glands, Graves' goiters, non toxic multinodular goiters and nodular and perinodular tissue of toxic nodular goiters show the same basa...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03350977
更新日期:1978-10-01 00:00:00
abstract::Endemic goiter in Morocco is localized in the Rif and Atlas mountains. In this study, performed in the Skoura-Toundoute areas (high Atlas), we demonstrate that iodine deficiency is the main factor involved in the development of endemic goiter. However it may not constitute the only etiological factor. The median urina...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03345821
更新日期:1993-01-01 00:00:00
abstract::Impaired glucose tolerance is present in many acromegalic patients and treatment with somatostatin analogs has variable effects on glycemic control. The aim of this study was to compare the effects of 2 somatostatin analogs on glucose metabolism, lanreotide slow release (L-SR) and octreotide long acting release (O-LAR...
journal_title:Journal of endocrinological investigation
pub_type: 临床试验,杂志文章
doi:10.1007/BF03345491
更新日期:2002-06-01 00:00:00
abstract::GH has a pivotal role in maintaining bone mass and metabolism both during childhood and in adult life. This effect depends on a complex interaction between circulating and peripherically produced GH and IGF-I. In vitro data and the use of genetically modified animals have greatly expanded the understanding of regulato...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00
abstract::Pyoderma gangrenosum is a rare chronic and recurrent skin disease characterized by progressing lesions from papulopustules to large necrotic sterile ulcers. Its definite etiology remains unknown. In a 40-year-old woman with typical pyoderma gangrenosum an intrasellar mass with suprasellar extension was diagnosed and r...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03349595
更新日期:1990-09-01 00:00:00
abstract::A comparison of peripheral patterns of androstenedione (A), 17 beta-estradiol (E2) and progesterone (P) is reported in ten infertile women during HMG-HCG induction of ovulation, in order to assess the site of ovarian secretion of plasma A and the possible influence on conception. Evidence for both the follicular and l...
journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
doi:10.1007/BF03351016
更新日期:1984-08-01 00:00:00