Assessment of diabetic retinopathy using two ultra-wide-field fundus imaging systems, the Clarus® and Optos™ systems.

abstract：BACKGROUND:The SRK/T formula is one of the third generation IOL calculation formulas. The purpose of this study was to evaluate the performance of the SRK/T formula in predicting a target refraction ±1.0D in short and long eyes using ultrasound biometry after phacoemulsification. METHODS:The present study was a retros...

journal_title：BMC ophthalmology

authors： Karabela Y,Eliacik M,Kaya F

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:To present a case of conjunctival lymphoma in a young woman complicated by pregnancy. CASE PRESENTATION:A 38-year-old previously healthy woman presented with a 2-year history of progressive right blepharoptosis. Giant papillomatous sessile masses were identified in the upper and lower fornix bilaterally and...

journal_title：BMC ophthalmology

authors： Ong SJ,Jung SM,Lin HC

更新日期：2017-07-27 00:00:00

abstract：BACKGROUND:We report a case of Meige's syndrome induced by an atypical antipsychotic (blonanserin) that presented with refractory dry eye disease. CASE PRESENTATION:A 37-year-old woman with a 6-month history of foreign body sensation in the eyes and difficulty in opening her eyes was treated at a local clinic for dry ...

journal_title：BMC ophthalmology

authors： Kim JE,Jung JW

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:Immune responses play a key role in the pathogenesis and progression of polypoidal choroidal vasculopath (PCV) and age-related macular degeneration (AMD). In this study, we determined the Th cell-associated immune responses by measuring the cytokine expression of peripheral blood mononuclear cells (PBMC) in ...

journal_title：BMC ophthalmology

authors： Yu Y,Ren XR,Wen F,Chen H,Su SB

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:Retinitis pigmentosa (RP) is a kind of inherited retinal degenerative diseases characterized by the progressive loss of photoreceptors. RP has been a conundrum without satisfactory countermeasures in clinic until now. Acetaldehyde dehydrogenase 2 (ALDH2), a major enzyme involved in aldehyde detoxification, h...

journal_title：BMC ophthalmology

authors： Yan W,Long P,Wei D,Yan W,Zheng X,Chen G,Wang J,Zhang Z,Chen T,Chen M

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:The repertoire of free-living protozoa in contact lens solutions is poorly known despite the fact that such protozoa may act as direct pathogens and may harbor intra-cellular pathogens. METHODS:Between 2009 and 2014, the contact lens solutions collected from patients presenting at our Ophthalmology Departme...

journal_title：BMC ophthalmology

authors： Bouchoucha I,Aziz A,Hoffart L,Drancourt M

更新日期：2016-10-29 00:00:00

abstract：BACKGROUND:Congenital cataract is the most frequent cause of blindness during infancy or early childhood. To date, more than 40 loci associated with congenital cataract have been identified, including at least 26 genes on different chromosomes associated with inherited cataract. This present study aimed to identify the...

journal_title：BMC ophthalmology

authors： Shen C,Wang J,Wu X,Wang F,Liu Y,Guo X,Zhang L,Cao Y,Cao X,Ma H

更新日期：2017-05-19 00:00:00

abstract：BACKGROUND:To assess visual outcomes over 24 months in patients with neovascular age-related macular degeneration (nAMD) who initiated intravitreal aflibercept therapy under a treat-and-extend (TE) regimen in real-world settings. METHODS:In this retrospective, observational, multicentre study in Slovenia, medical reco...

journal_title：BMC ophthalmology

authors： Jaki Mekjavić P,Gregorčič B,Oberč C,Podgoršek S

更新日期：2018-12-20 00:00:00

abstract：BACKGROUND:P66Shc is partially localised within the mitochondrial fraction. It is primarily related to the generation of mitochondrial reactive oxygen species and apoptosis. Based on previous studies, we hypothesize that in the retina, p66Shc may exist and affect the development of diabetic retinopathy. The purpose of ...

journal_title：BMC ophthalmology

authors： Zhao MH,Hu J,Li S,Wu Q,Lu P

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:Retinal vein occlusion (RVO) is a common retinal venous disorder that causes vision loss. No specific therapy has been developed. Controversy exists regarding two treatments: intravitreal dexamethasone implants and anti-vascular endothelial growth factor (VEGF). The goal of this study is to compare the effec...

journal_title：BMC ophthalmology

authors： Gao L,Zhou L,Tian C,Li N,Shao W,Peng X,Shi Q

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:Ocular signs of Fabry disease can be seen in the first decade of life. METHODS:We examined the occurrence of ocular signs in 232 paediatric patients in the Fabry Outcome Survey (FOS) international registry and looked for relationships between the presence of eye findings and disease severity as measured by ...

journal_title：BMC ophthalmology

authors： Kalkum G,Pitz S,Karabul N,Beck M,Pintos-Morell G,Parini R,Rohrbach M,Bizjajeva S,Ramaswami U

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological platforms to reveal transcriptome profiles and identify any differentially expressed genes...

journal_title：BMC ophthalmology

authors： Song WP,Zheng S,Yao HJ,Zhou XF,Li R,Zhang CY,Zhao JY,Wang LW,Shao RG,Li L

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:Orbital exenteration is a disfiguring procedure that aims to achieve local control. It is commonly a part of the management of malignant orbital tumor which is a life-threatening condition. It is necessary to determine predictive factors associated with overall survival (OS) following orbital exenteration. ...

journal_title：BMC ophthalmology

authors： Aryasit O,Preechawai P,Hirunpat C,Horatanaruang O,Singha P

更新日期：2018-07-28 00:00:00

abstract：BACKGROUND:The effectiveness of ranibizumab in the treatment of diabetic macular edema has been proven with large clinical trials. For bevacizumab only two clinical trials have been published and a head-to-head comparison is lacking to date. However, if proved non-inferior to ranibizumab, use of the off-label bevacizum...

journal_title：BMC ophthalmology

authors： Schauwvlieghe AM,Dijkman G,Hooymans JM,Verbraak FD,Hoyng CB,Dijkgraaf MG,Van Leeuwen R,Vingerling JR,Moll AC,Schlingemann RO

更新日期：2015-07-07 00:00:00

abstract：BACKGROUND:To evaluate the efficacy, complications, and clinical characteristics, including the ocular toxicity, of intravitreal melphalan(IVM) treatment for vitreous seeding in Chinese retinoblastoma patients. METHODS:This was a retrospective, non-comparative analysis including 30 consecutive eyes of 23 patients with...

journal_title：BMC ophthalmology

authors： Xue K,Ren H,Meng F,Zhang R,Qian J

更新日期：2019-02-26 00:00:00

abstract：BACKGROUND:Because latanoprost and the original formulation of travoprost that included benzalkonium chloride (BAK) have been shown to be similar with regard to tolerability, we compared initial topical intraocular pressure (IOP)-lowering medication change rates in patients newly treated with latanoprost or travoprost-...

journal_title：BMC ophthalmology

authors： Fain JM,Kotak S,Mardekian J,Bacharach J,Edward DP,Rauchman S,Brevetti T,Fox JL,Lovelace C

更新日期：2011-06-13 00:00:00

abstract：BACKGROUND:To study the healing processes of partial thickness wounds in the adult rabbit cornea after grafting a porous collagen-glycosaminoglycan copolymer matrix (CG). METHODS:In this study, the regeneration of surgically-induced rabbit corneal defect implanted with CG was investigated. The corneal partial thicknes...

journal_title：BMC ophthalmology

authors： Wu SY,Pan CY,Shen EP,Tzeng IS,Hsu WC

更新日期：2018-10-25 00:00:00

abstract：BACKGROUND:Congenital cataract (CC) is a significant cause of lifelong visual loss, and its genetic diagnosis is challenging due to marked genetic heterogeneity. The purpose of this article is to report the genetic findings in sporadic and familial CC patients. METHODS:Patients (n = 53) who were clinically diagnosed w...

journal_title：BMC ophthalmology

authors： Fan F,Luo Y,Wu J,Gao C,Liu X,Mei H,Zhou X

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:To evaluate the safety and effectiveness of the Visian Implantable Collamer Lens (ICL) implantation in high myopic patients with inactive Graves' ophthalmopathy (GO) by observing the changes of choroidal thickness (CT). METHODS:Eight patients (16 eyes) with high myopia accompanied with inactive GO were sele...

journal_title：BMC ophthalmology

authors： He F,Liu Y,Jia R,Zhang J

更新日期：2020-08-25 00:00:00

abstract：BACKGROUND:Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with this impact. METHODS:Six focus group sessions were conducted at t...

journal_title：BMC ophthalmology

authors： Yeo S,Tong L

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:Diabetic macular edema (DME) can be treated with different alternatives, among them Dexamethasone intravitreal implant 0.7 mg (DEX 0.7) has demonstrated that may improve both central macular thickness (CMT) and best corrected visual acuity (BCVA). This study aimed to evaluate the effect of the intravitreal d...

journal_title：BMC ophthalmology

authors： Castro-Navarro V,Cervera-Taulet E,Navarro-Palop C,Monferrer-Adsuara C,Hernández-Bel L,Montero-Hernández J

更新日期：2019-01-11 00:00:00

abstract：BACKGROUND:To analyse the associated factors, diagnosis, clinical manifestations and therapeutic effects of Acanthamoeba keratitis at a tertiary ophthalmic centre in Southern China. METHODS:A retrospective clinical study was performed in fifteen patients who were admitted to Zhongshan Ophthalmic Centre (ZOC) from Janu...

journal_title：BMC ophthalmology

authors： Zhong J,Li X,Deng Y,Chen L,Zhou S,Huang W,Lin S,Yuan J

更新日期：2017-10-02 00:00:00

abstract：BACKGROUND:The aim of this study was to estimate both the direct and indirect annual costs of treating bacterial conjunctivitis (BC) in the United States. This was a cost of illness study performed from a U.S. healthcare payer perspective. METHODS:A comprehensive review of the medical literature was supplemented by da...

journal_title：BMC ophthalmology

authors： Smith AF,Waycaster C

更新日期：2009-11-25 00:00:00

abstract：BACKGROUND:Glaucoma is a progressive disease responsible for the second commonest cause of blindness in the UK. Identifying appropriate patients for hospital care remains an ongoing challenge for all UK hospital glaucoma services. The purpose of our study is to evaluate accuracy and outcome of community optometry refer...

journal_title：BMC ophthalmology

authors： El-Assal K,Foulds J,Dobson S,Sanders R

更新日期：2015-12-07 00:00:00

abstract：BACKGROUND:The gold standard treatments in amblyopia are penalizing therapies, such as patching or blurring vision with atropine that are aimed at forcing the use of the amblyopic eye. However, in the last years, new therapies are being developed and validated, such as dichoptic visual training, aimed at stimulating th...

journal_title：BMC ophthalmology

authors： Žiak P,Holm A,Halička J,Mojžiš P,Piñero DP

更新日期：2017-06-28 00:00:00

abstract：BACKGROUND:To evaluate the 6-month clinical outcomes of Flexivue Microlens refractive corneal inlay in emmetropic patients in Asia for the surgical compensation of presbyopia. METHODS:In this retrospective study, corneal inlay implantation was done using a femtosecond laser. The follow-up period was 6 months. Near/int...

journal_title：BMC ophthalmology

authors： Han G,Lim DH,Yang CM,Park GH,Park DY,Moon HS,Lee JM,Lee JH,Chung TY

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:To predict the effectiveness of topical glaucoma medications based on initial uniocular and binocular treatment. To test a traditional hypothesis that effectiveness following a uniocular trial is associated with the change in IOP in the initially treated eye minus the change in the initially untreated eye. T...

journal_title：BMC ophthalmology

authors： Leffler CT,Amini L

更新日期：2007-10-05 00:00:00

abstract：BACKGROUND:To investigate the effect of idiopathic epiretinal membrane (ERM) on the retinal-image quality and psychophysical contrast sensitivity function (CSF). METHODS:Forty-four subjects with diagnosis of idiopathic unilateral ERM were enrolled in this cross-sectional observational clinical study. The fellow unaffe...

journal_title：BMC ophthalmology

authors： Liu L,Wang Y,Liu J,Liu W

更新日期：2018-11-07 00:00:00

abstract：BACKGROUND:To evaluate the structural changes associated with visual acuity (VA) in patients with idiopathic macular telangiectasia (MT) type 1 using multimodal imaging modalities. METHODS:A retrospective study of 14 patients with MT type 1 and of 10 eyes from 10 healthy individuals as age-matched controls was conduct...

journal_title：BMC ophthalmology

authors： Guo J,Tang W,Ye X,Wu H,Xu G,Liu W,Zhang Y

更新日期：2018-03-05 00:00:00

abstract：:Ophthalmologists and researchers in ophthalmology understand what a rapidly evolving field ophthalmology is, and that to conduct good research it is essential to use the latest and best methods. In outcomes research, one modern initiative has been to conduct holistic measurement of outcomes inclusive of the patient's ...

journal_title：BMC ophthalmology

authors： Pesudovs K

更新日期：2006-06-15 00:00:00