Abstract：
BACKGROUND:Orbital exenteration is a disfiguring procedure that aims to achieve local control. It is commonly a part of the management of malignant orbital tumor which is a life-threatening condition. It is necessary to determine predictive factors associated with overall survival (OS) following orbital exenteration. METHODS:This was a retrospective, comparative, case series of 39 patients with malignant tumors who underwent orbital exenteration. Patient records were reviewed for age, clinical presentation, preoperative visual acuity (VA), tumor size, surgical margin, tumor invasiveness, recurrent disease, and status of distant metastasis. Kaplan-Meier curves were used to assess OS and event-free survival (EFS). The predictive factors related to OS were identified using multivariate analysis. RESULTS:The mean age was 62.9 years (range, 5.5 to 89.7 years), 68.4% presented with VA < 20/400. The mean size of all tumors was 32 ± 18 mm. Distant metastasis at diagnosis was reported in 11 patients (28.2%). Twenty-two patients died during follow-up. The median OS and EFS were 3.89 years and 3.01 years, respectively. The predictive factors for worse OS on multivariate analysis were preoperative VA < 20/400 (adjusted hazard ratio [aHR] 4.67, P = 0.003), tumor size larger than 20 mm (aHR 3.14, P = 0.022,) and positive distant metastasis at diagnosis (aHR 15.31, P < 0.001). CONCLUSIONS:The prognostic factors for poor survival outcome following orbital exenteration were a preoperative VA < 20/400, tumor size > 20 mm, and distant metastasis at diagnosis mostly due to patient negligence.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Aryasit O,Preechawai P,Hirunpat C,Horatanaruang O,Singha Pdoi
10.1186/s12886-018-0850-ysubject
Has Abstractpub_date
2018-07-28 00:00:00pages
186issue
1issn
1471-2415pii
10.1186/s12886-018-0850-yjournal_volume
18pub_type
杂志文章abstract：BACKGROUND:To screen for visual impairment in Malaysian preschool children. METHODS:Visual screening was conducted in 400 preschool children aged 4 to 6 years. The screening involved two basic procedures; the distant visual acuity test using the Sheridan Gardiner chart and the depth perception test using the Langs ste...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-13-16
更新日期：2013-04-19 00:00:00
abstract：BACKGROUND:Central corneal thickness (CCT) measurement has become an important test in the diagnosis and management of glaucoma. Currently, ultrasound corneal thickness measurement (pachymetry) is the most frequently used clinical technique and the gold standard to assess CCT. Newer instruments are currently available ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-015-0116-x
更新日期：2015-09-29 00:00:00
abstract：:Meibomian gland dysfunction (MGD) is the major cause of evaporative dry eye disease (EDED) and dysfunction is widely thought to mechanistically involve ductal hyperkeratinization, plugging and obstruction. This review re-evaluates the role of hyperkeratinization in MGD based on more recent findings from mouse models. ...
journal_title：BMC ophthalmology
pub_type： 杂志文章,评审
doi：10.1186/s12886-015-0132-x
更新日期：2015-12-17 00:00:00
abstract：:Mucins locate to the apical surfaces of all wet-surfaced epithelia including ocular surface. The functions of the mucins include anti-adhesive, lubrication, water retention, allergens and pathogen barrier function. Ocular surface pathologies, i.e. dry eye syndrome or allergic conjunctivitis, are reportedly associated ...
journal_title：BMC ophthalmology
pub_type： 杂志文章,评审
doi：10.1186/s12886-015-0137-5
更新日期：2015-12-17 00:00:00
abstract：BACKGROUND:Perfluorocarbon liquid (PFCL) is widely used as an intraoperative heavy tamponade to flatten the retina and is replaced with silicone oil (SO) at the end of the surgery. Due to the long tamponade period, the SO is known to remain attached to the retina at the time of removal, and is commonly termed "sticky o...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0745-y
更新日期：2018-03-27 00:00:00
abstract：BACKGROUND:To investigate machine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-box" approaches, for automated diagnosis of Age-related Macular Degeneration (AMD). METHODS:Data from healthy subjects and patients diagnosed with AMD or other retinal diseases were collecte...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-15-10
更新日期：2015-01-27 00:00:00
abstract：BACKGROUND:In this analysis, we aimed to systematically compare the complications which were associated with femtosecond laser-assisted cataract surgery (FLACS) versus the conventional phacoemulsification surgery (CPE). METHODS:Commonly used search databases, specifically MEDLINE, Cochrane Central, EMBASE, and http://...
journal_title：BMC ophthalmology
pub_type： 杂志文章,meta分析
doi：10.1186/s12886-019-1190-2
更新日期：2019-08-09 00:00:00
abstract：BACKGROUND:Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy, orbital inflammation and pain which may mimic ophthalmic Graves' diseas...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0672-y
更新日期：2018-01-12 00:00:00
abstract：BACKGROUND:Nocardia infection is uncommon in clinical practice, with most cases occuring as the result of opportunistic infection in immunocompromsed patients. Here, we report a case of disseminated nocardiosis with subretinal abscess in a patient with nephrotic syndrome, and whom is receiving immunosuppressive therapy...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0883-2
更新日期：2018-09-03 00:00:00
abstract：BACKGROUND:To report a patient who presented with bluish scleral discoloration, keratoconus, and progressive high myopia. CASE PRESENTATION:A 6-year-old Chinese female patient presented with a significant bluish discoloration of the sclera in both eyes and extreme corneal thinning with anterior corneal protrusion. Gen...
journal_title：BMC ophthalmology
pub_type： 杂志文章,评审
doi：10.1186/s12886-018-0903-2
更新日期：2018-09-18 00:00:00
abstract：BACKGROUND:To report patients with age-related macular degeneration and atypical central retinal pigment epithelium (RPE) defects not attributable to geographic atrophy (GA) or RPE-tears with overlying preserved photoreceptor layers. METHODS:Multimodal imaging case-series evaluating the course of atypical RPE- defects...
journal_title：BMC ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1186/s12886-017-0452-0
更新日期：2017-05-15 00:00:00
abstract：BACKGROUND:This multicentre, retro-prospective real-world study evaluated the visual, refractive and safety outcomes of a monofocal lens 1 year after implantation in cataract patients with or without pre-existing ocular pathologies. METHODS:Records from 4 centres in Germany and Sweden were reviewed to select eyes with...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01493-y
更新日期：2020-06-11 00:00:00
abstract：BACKGROUND:There is no generally accepted medical or surgical treatment to stop the progressive course of retinitis pigmentosa. Previous studies have suggested lutein as a potential treatment with positive effects on macular pigment density. The objective of this study was to examine the effect of lutein supplementatio...
journal_title：BMC ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1186/1471-2415-6-23
更新日期：2006-06-07 00:00:00
abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a life-threatening hematological condition associated with deficiency in ADAMTS13. Ocular manifestations associated with TTP are uncommon. CASE PRESENTATION:Here we report a case where a 44 year old female patient with a history of symptomatic anemia and cotton w...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01719-z
更新日期：2020-11-19 00:00:00
abstract：BACKGROUND:Patients' feedback is of great importance in health care policy decisions. The Consumer Quality Index Cataract Questionnaire (CQI Cataract) was used to measure patients' experiences with quality of care after a cataract operation. This study aims to evaluate the reliability and the dimensional structure of t...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-7-14
更新日期：2007-09-19 00:00:00
abstract：BACKGROUND:To investigate the clinical features of diabetic macular edema (DME) in eyes with pachychoroid phenotypes using multimodal retinal imaging. METHODS:We retrospectively reviewed 210 eyes from 210 DME patients and analyzed the clinical and imaging parameters, including visual acuity, central macular thickness ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01663-y
更新日期：2020-10-02 00:00:00
abstract：BACKGROUND:A description of the diagnostic features of Miller Fisher syndrome. CASE PRESENTATION:The clinical presentation, investigation, and subsequent progress of our patient with clinical unilateral external ophthalmoplegia. CONCLUSION:Our case demonstrates the presentation of clinical unilateral external ophthal...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-7-7
更新日期：2007-04-17 00:00:00
abstract：BACKGROUND:The use of capsular tension ring (CTR) implantation to treat cataract patients with weak zonules is still controversial. The aim of this study was to examine the effects of CTR implantation on capsular stability after phacoemulsification in patients with weak zonules, especially patients who have undergone p...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01772-8
更新日期：2021-01-07 00:00:00
abstract：BACKGROUND:Previous techniques resulted with low rates of successful fusion after the surgeries and high necessity of additional surgeries in the treatment of thyroid orbitopathy related strabismus. In this study, reviewing the results of our patients who had surgical correction with relaxed muscle positioning techniqu...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0974-0
更新日期：2018-11-23 00:00:00
abstract：BACKGROUND:The aim of this study was to estimate both the direct and indirect annual costs of treating bacterial conjunctivitis (BC) in the United States. This was a cost of illness study performed from a U.S. healthcare payer perspective. METHODS:A comprehensive review of the medical literature was supplemented by da...
journal_title：BMC ophthalmology
pub_type： 杂志文章,评审
doi：10.1186/1471-2415-9-13
更新日期：2009-11-25 00:00:00
abstract：BACKGROUND:Cataract surgery in diabetics is more technically challenging due to a number of factors including poor intraoperative pupil dilation and a higher risk of vision threatening complications. This study evaluates the safety and efficacy of an intracameral combination of 2 mydriatics and 1 anesthetic (ICMA, Mydr...
journal_title：BMC ophthalmology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1186/s12886-020-01343-x
更新日期：2020-03-03 00:00:00
abstract：BACKGROUND:Older drivers have a crash rate nearly equal to that of young drivers whose crash rate is the highest among all age groups. Contrast sensitivity impairment is common in older adults. The purpose of this study is to examine whether parameters from the photopic and mesopic contrast sensitivity functions (CSF) ...
journal_title：BMC ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1186/s12886-020-1331-7
更新日期：2020-02-04 00:00:00
abstract：BACKGROUND:To analyze the clinical characteristics, treatment and prognosis of children with unilateral retinoblastoma (RB) and intracranial segment of retrobulbar optic nerve invasion. METHODS:A total of 14 children with unilateral RB and intracranial segment of retrobulbar optic nerve invasion were enrolled in this ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01768-4
更新日期：2021-01-14 00:00:00
abstract：BACKGROUND:Previous studies described cases of Ocriplasmin injections in patients with vitreo-macular traction and reduced central visual acuity. We describe the first case of a patient with 20/20 visual acuity and vitreo-macular traction treated with Ocriplasmin, and, for the first time in literature, we evaluated the...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-015-0141-9
更新日期：2015-10-29 00:00:00
abstract：BACKGROUND:The repertoire of free-living protozoa in contact lens solutions is poorly known despite the fact that such protozoa may act as direct pathogens and may harbor intra-cellular pathogens. METHODS:Between 2009 and 2014, the contact lens solutions collected from patients presenting at our Ophthalmology Departme...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0370-6
更新日期：2016-10-29 00:00:00
abstract：BACKGROUND:To analyse the associated factors, diagnosis, clinical manifestations and therapeutic effects of Acanthamoeba keratitis at a tertiary ophthalmic centre in Southern China. METHODS:A retrospective clinical study was performed in fifteen patients who were admitted to Zhongshan Ophthalmic Centre (ZOC) from Janu...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0571-7
更新日期：2017-10-02 00:00:00
abstract：BACKGROUND:To report a case of orbital inflammation after bisphosphonate infusion in a patient who was already receiving immunosuppressive therapy. CASE PRESENTATION:A 56-year-old woman presented to the ophthalmology clinic with acute onset of right eye pain 24 h after receiving her first Zolendronic acid infusion. Sh...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1063-8
更新日期：2019-02-14 00:00:00
abstract：BACKGROUND:To compare the efficacy of phacoemulsification (PKE) combined with nonpenetrating deep sclerectomy (NPDS) with mitomycin C (MMC) versus XEN® gel stent with MMC. METHODS:In this nonrandomized, retrospective, comparative, single-center pilot study, 105 consecutive eyes of 75 patients with uncontrolled primary...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01492-z
更新日期：2020-06-16 00:00:00
abstract：BACKGROUND:To evaluate the 6-month clinical outcomes of Flexivue Microlens refractive corneal inlay in emmetropic patients in Asia for the surgical compensation of presbyopia. METHODS:In this retrospective study, corneal inlay implantation was done using a femtosecond laser. The follow-up period was 6 months. Near/int...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1069-2
更新日期：2019-03-05 00:00:00
abstract：BACKGROUND:Since the normative value of the retinal macular thickness is undocumented in the Middle East, the aim of this work is to assess the normative values of the macular thickness in healthy eyes in a Middle Eastern population and its relationship with age, sex, and laterality. METHODS:One hundred sixteen indivi...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01391-3
更新日期：2020-04-07 00:00:00
