Abstract:
BACKGROUND:Nocardia infection is uncommon in clinical practice, with most cases occuring as the result of opportunistic infection in immunocompromsed patients. Here, we report a case of disseminated nocardiosis with subretinal abscess in a patient with nephrotic syndrome, and whom is receiving immunosuppressive therapy. CASE PRESENTATION:A 58-year-old male presented with decreased vision in his left eye, without redness or floaters, which had persisted for three days. The patient had previously been diagnosed with membranous nephropathy, and as such, had received systemic corticosteroid therapy for four months. Further, the patient had developed pneumonia three weeks prior to this presentation. The ocular lesion appeared as a creamy-white subretinal abscess, with overlying retinal hemorrhages. Subsequent administration of three intravitreal injections of vancomycin and ceftazidime ultimately led to eradication of the intraocular infection, however, two months later, the patient developed a brain abcess. Pathogens isolated from the blood were subsequently identified as Nocardia. The patient was successfully treated via systemic administration of imipenem and trimethoprim-sulfamethoxazole. CONCLUSIONS:Clinicians should be aware of the possibility of Nocardia infections within all immunocompromised patients, as well as the tendency of this infection to disseminate--particularly in the brain. The early detection of Nocardia infections and prolonged treatment of the proper antibiotics may significantly improve the prognosis of this life-threatening infection.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Xu H,Fu B,Xu L,Sun Jdoi
10.1186/s12886-018-0883-2subject
Has Abstractpub_date
2018-09-03 00:00:00pages
234issue
1issn
1471-2415pii
10.1186/s12886-018-0883-2journal_volume
18pub_type
杂志文章abstract:BACKGROUND:Orbital cellulitis is a rare cause of exudative retinal detachment. Hereby, we aimed to report the first case of exudative retinal detachment derived from orbital cellulitis in mainland China. CASE PRESENTATION:A 16-year-old girl developed severe left orbital cellulitis in 4 days. Two exudative retinal deta...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01596-6
更新日期:2020-08-17 00:00:00
abstract:BACKGROUND:Nonarteritic ischemic optic neuropathy affects the anterior portion of the optic nerve and is characterized by sudden, painless visual loss. The affected eye has a relative afferent pupillary defect. The typical funduscopic appearance includes optic disc edema, with associated nerve fiber layer hemorrhage. R...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-6-32
更新日期:2006-10-11 00:00:00
abstract:BACKGROUND:To report a case of multiple evanescent white dot syndrome (MEWDS) following simultaneous rabies vaccination. CASE PRESENTATION:Review of the clinical, laboratory, photographic, optical coherence tomographic (OCT), fundus autofluorescent, angiographic, electrophysiologic, and perimetric records of a patient...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0968-y
更新日期:2018-12-07 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate the efficacy and safety of transepithelial corneal collagen crosslinking (transepithelial CXL) versus standard corneal collagen crosslinking (epithelium-off CXL) on keratoconus. METHODS:Eligible studies were identified by systematically searching PubMed, the Cochrane Li...
journal_title:BMC ophthalmology
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12886-017-0657-2
更新日期:2017-12-28 00:00:00
abstract:BACKGROUND:The present study sought to introduce clinical characteristics and stepwise surgical strategies of isolated complete cryptophthalmos, a rare, congenital ocular anomaly. CASE PRESENTATION:Retrospective, noncomparative, clinical study. Six patients with isolated complete cryptophthalmos were diagnosed at the ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1170-6
更新日期:2019-07-31 00:00:00
abstract:BACKGROUND:Surgery for trichiasis is one of the pillars of the World Health Organization's strategy for global elimination of trachoma as a public health problem. A high incidence of post-operative trichiasis or other poor surgical outcomes could jeopardize these efforts. In this review, we aimed to summarize the repor...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01564-0
更新日期:2020-11-17 00:00:00
abstract:BACKGROUND:To report the prevalence of ocular abnormalities and investigate visual acuity in a large cohort of retinitis pigmentosa (RP) patients in Western China. METHODS:The medical records and ophthalmic examination reports of 2127 eyes of 1065 RP patients at one eye hospital were retrospectively reviewed to determ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01797-z
更新日期:2021-01-18 00:00:00
abstract:BACKGROUND:To present a case report of a patient with a mixed choroidal neovascular membrane (CNV) with an asymmetric response to ranibizumab diagnosed on optical coherence tomography angiography (OCTa). CASE PRESENTATION:A 61-year-old male was referred to our department in September 2017 due to decreased vision in hi...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-021-01810-z
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:To examine the clinical features of acute acquired comitant esotropia (AACE) and to evaluate the clinical effectiveness of a single injection of botulinum toxin type A (BTXA) on binocular visual function (BVF). METHODS:This retrospective, observational case series study enrolled patients with AACE examined ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01739-9
更新日期:2020-11-25 00:00:00
abstract::Conjunctival and subconjunctival fibrogenesis and inflammation are sight compromising side effects that can occur subsequent to glaucoma filtration surgery. Despite initial declines in intraocular pressure resulting from increasing aqueous outflow, one of the activated responses includes marshalling of proinflammatory...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-015-0134-8
更新日期:2015-12-17 00:00:00
abstract:BACKGROUND:Sclopetaria is a rare ophthalmic finding in trauma CASE PRESENTATION:This is a report of a patient who developed macular holes from sclopetaria induced by indirect trauma. A 22-year-old male, suffered a gunshot wound that passed behind his eyes, resulting in bilateral macular hole formation CONCLUSION:To o...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-10-6
更新日期:2010-03-19 00:00:00
abstract:BACKGROUND:To screen for visual impairment in Malaysian preschool children. METHODS:Visual screening was conducted in 400 preschool children aged 4 to 6 years. The screening involved two basic procedures; the distant visual acuity test using the Sheridan Gardiner chart and the depth perception test using the Langs ste...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-13-16
更新日期:2013-04-19 00:00:00
abstract:BACKGROUND:Acute acquired comitant esotropia (AACE) is a type of strabismus characterized by a sudden onset of large angle esotropia with diplopia, which often occurs in children after infancy, teenagers, and young adolescents. However, studies on the surgical outcomes of only adults are rare. The purpose of this artic...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01793-3
更新日期:2021-01-18 00:00:00
abstract:BACKGROUND:To understand the clinical and economic outcomes of treatments for managing complications of ischemic central retinal vein occlusion (iCRVO). METHODS:We conducted a systematic literature review by searching multiple databases and ophthalmology conferences from 2004 to 2015. Studies published in English lang...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-016-0282-5
更新日期:2016-07-11 00:00:00
abstract:BACKGROUND:To describe the characteristics of patients with syphilitic uveitis in northern China. METHODS:A case series of 21 patients (33 eyes) diagnosed with syphilitic uveitis from 2011 to 2016 at a tertiary center in northern China was retrospectively analyzed. RESULTS:Twenty-one patients (33 eyes) were diagnosed...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0491-6
更新日期:2017-06-19 00:00:00
abstract:BACKGROUND:Silicone oil tamponade is more frequently reserved for cases of complex retinal detachment. We describe the effects of different variations in oil ratios with the relatively unknown technique of double oil tamponade. METHODS:Retrospective case note review of nine patients with complex rhegmatogenous retinal...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0660-7
更新日期:2017-12-28 00:00:00
abstract:BACKGROUND:There is a huge need for the availability of transplantable donor corneas worldwide to reduce the burden of corneal blindness due to corneal opacity. Voluntary eye donation depends on the awareness levels of various stakeholders in the community. This study aimed to assess the awareness level regarding eye d...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-25
更新日期:2014-03-06 00:00:00
abstract:BACKGROUND:Docetaxel is a chemotherapeutic agent of the taxane class of drugs for the treatment of breast cancer. We present a female patient who noted decreased vision after docetaxel treatment. CASE PRESENTATION:A 45-year-old female patient received docetaxel treatment after resection of a breast carcinoma. Fundusco...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0020-4
更新日期:2015-03-29 00:00:00
abstract:BACKGROUND:To report a rare case of bilateral Purtscher-like retinopathy in a Chinese female patient with dermatomyositis. CASE PRESENTATION:An 18-year-old woman with lower extremity muscle weakness was admitted due to decreased vision of both eyes for two weeks. Ophthalmic examination revealed violaceous eruption on ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-13-36
更新日期:2013-07-24 00:00:00
abstract:BACKGROUND:To study the influencing factors for different healing patterns of patients with idiopathic macular holes (IMH) after vitrectomy surgery performed with the internal limiting membrane (ILM) flap technique. METHODS:This study was a retrospective, consecutive, observational case series study. We recruited 52 I...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1265-0
更新日期:2019-12-21 00:00:00
abstract:BACKGROUND:To evaluate the effects of anterior capsular opening size on deviation from predicted refraction and the effective position of the intraocular lens (ELP) in cataract surgery. METHODS:Nonrandomized clinical trial. Eighty patients (80 eyes) with simple age-related cataracts were treated from May 2018 to Septe...
journal_title:BMC ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1186/s12886-019-1068-3
更新日期:2019-02-21 00:00:00
abstract:BACKGROUND:Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with this impact. METHODS:Six focus group sessions were conducted at t...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0671-z
更新日期:2018-01-16 00:00:00
abstract:BACKGROUND:The SRK/T formula is one of the third generation IOL calculation formulas. The purpose of this study was to evaluate the performance of the SRK/T formula in predicting a target refraction ±1.0D in short and long eyes using ultrasound biometry after phacoemulsification. METHODS:The present study was a retros...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0271-8
更新日期:2016-07-08 00:00:00
abstract:BACKGROUND:To report a patient who presented with bluish scleral discoloration, keratoconus, and progressive high myopia. CASE PRESENTATION:A 6-year-old Chinese female patient presented with a significant bluish discoloration of the sclera in both eyes and extreme corneal thinning with anterior corneal protrusion. Gen...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-018-0903-2
更新日期:2018-09-18 00:00:00
abstract:BACKGROUND:The ability to image wide fundus fields and to conduct swift, non-invasive examinations is increasingly important with the escalation in patients with diabetic retinopathy (DR). METHODS:Fifty eyes of 28 consecutive patients with DR were examined in this prospective observational study. A total of 46 eyes, 2...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-1011-z
更新日期:2018-12-20 00:00:00
abstract:BACKGROUND:Surgeons may be unaware of the ability of plant toxins to cause corneal damage. Therefore, corneal damage following intraocular surgery due to plant toxins may be misdiagnosed as postoperative infection. CASE PRESENTATION:A 74-year-old man presented with hyperemia and reduced visual acuity in both eyes 6 we...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0400-z
更新日期:2017-01-18 00:00:00
abstract:BACKGROUND:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening conditions that initially affect the skin and mucous membranes. The aim of this study was to compare the acute ocular manifestations between SJS and TEN. METHODS:The initial presenting ophthalmic records of pat...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0464-9
更新日期:2017-05-12 00:00:00
abstract:BACKGROUND:This is a case of spontaneous toric implantable collamer lens (TICL) rotation that occurred twice in the left eye of a patient. CASE PRESENTATION:A 24-year-old gentleman received TICL implantation for treatment of myopic astigmatism encountered with spontaneous rotation of approximately 90° from its origina...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01597-5
更新日期:2020-08-28 00:00:00
abstract:BACKGROUND:To report clinical features and risk factors of post-cataract surgery endophthalmitis (PE) due to Stenotrophomonas maltophilia. METHODS:A retrospective case review from December 10, 2010 to April 7, 2011 was performed at the Eye & ENT Hospital, Fudan University. Data were collected for surgical details, dis...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-15-14
更新日期:2015-01-24 00:00:00
abstract:BACKGROUND:A patient's health literacy is fundamental for navigating the health system and managing disease. This study aimed to compare the health literacy levels of patients with chronic retinal disease in Denmark. METHODS:This cross-sectional questionnaire study used the validated HLS-EU-Q16 questionnaire to determ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1191-1
更新日期:2019-08-08 00:00:00