Abstract:
BACKGROUND:To study the influencing factors for different healing patterns of patients with idiopathic macular holes (IMH) after vitrectomy surgery performed with the internal limiting membrane (ILM) flap technique. METHODS:This study was a retrospective, consecutive, observational case series study. We recruited 52 IMH patients who underwent vitrectomy with the ILM flap technique. The participants were divided into 2 groups: group A (25 patients), without significant glial cell proliferation in the macular area on postoperative optical coherence tomography (OCT); and group B (27 patients), with significant glial cell proliferation. The postoperative visual acuity (VA), external limiting membrane (ELM) and ellipsoid zone (EZ) recovery characteristics were compared between the two groups. RESULTS:There were statistically significant differences in minimum linear diameter (MLD) of the macular hole and postoperative VA (p = 0.02, 2.81 E-4 respectively) between the two groups. Compared with patients in group A, patients in group B had poorer VA and EZ recovery in the first 12 months after surgery, and a longer ELM recovery period. The OCT results showed that patients in group B had more extensive ILM filling in the macular area after surgery than patients in group A. CONCLUSION:The presence of aberrant glial cell proliferation was related to a larger MLD of the IMH, and the filling approach for the ILM during the operation was related to the postoperative healing pattern and vision acuity.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Liu Y,Wu C,Wang Y,Dong Y,Liang D,Xiao B,Han Q,Chu Ydoi
10.1186/s12886-019-1265-0subject
Has Abstractpub_date
2019-12-21 00:00:00pages
264issue
1issn
1471-2415pii
10.1186/s12886-019-1265-0journal_volume
19pub_type
杂志文章abstract:BACKGROUND:Silicone oil tamponade has become a mainstay in treatment of advanced retinal detachment due to multiple etiologies. The aim of this study is to assess the characteristics, fates and complications of long-term silicone oil tamponade after par plana vitrectomy (PPV), and to compare the outcomes of different s...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01608-5
更新日期:2020-08-17 00:00:00
abstract:BACKGROUND:There is a huge need for the availability of transplantable donor corneas worldwide to reduce the burden of corneal blindness due to corneal opacity. Voluntary eye donation depends on the awareness levels of various stakeholders in the community. This study aimed to assess the awareness level regarding eye d...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-25
更新日期:2014-03-06 00:00:00
abstract:BACKGROUND:The gold standard treatments in amblyopia are penalizing therapies, such as patching or blurring vision with atropine that are aimed at forcing the use of the amblyopic eye. However, in the last years, new therapies are being developed and validated, such as dichoptic visual training, aimed at stimulating th...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0501-8
更新日期:2017-06-28 00:00:00
abstract:BACKGROUND:Ocular hypotony results in an increased break down of the blood-aqueous barrier and an increase in inflammatory mediator release. We postulate that this release may lead to an increased risk of trabeculectomy failure through increased bleb scarring. This study was designed to try to address the question if h...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-5-7
更新日期:2005-04-05 00:00:00
abstract:BACKGROUND:To examine the clinical features of acute acquired comitant esotropia (AACE) and to evaluate the clinical effectiveness of a single injection of botulinum toxin type A (BTXA) on binocular visual function (BVF). METHODS:This retrospective, observational case series study enrolled patients with AACE examined ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01739-9
更新日期:2020-11-25 00:00:00
abstract:BACKGROUND:To evaluate therapeutic outcomes of interferon alpha-2a (IFNα2a) treatment in patients with Behcet's disease who were refractory to immunosuppressive agents. METHODS:This retrospective case series reviewed the medical records of 5 patients with refractory Behcet uveitis from January 2011 to February 2017. I...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0719-0
更新日期:2018-02-20 00:00:00
abstract:BACKGROUND:Lateralization of horizontal semicircular canal benign paroxysmal positional vertigo (HSC-BPPV) is very important for successful repositioning. The directions of lying-down nystagmus (LDN) and head-bending nystagmus (HBN) have been used as ancillary findings to identify the affected sites. This retrospective...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-136
更新日期:2014-11-20 00:00:00
abstract:BACKGROUND:Myopic foveoschisis (MF) is among the leading causes of visual loss in high myopia. However, it remains controversial whether internal limiting membrane (ILM) peeling or gas tamponade is necessary treatment option for MF. METHODS:PubMed, EMBASE, CBM, CNKI, WANFANG DATA and VIP databases were systematically ...
journal_title:BMC ophthalmology
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12886-017-0562-8
更新日期:2017-09-08 00:00:00
abstract:BACKGROUND:To report a case of orbital inflammation after bisphosphonate infusion in a patient who was already receiving immunosuppressive therapy. CASE PRESENTATION:A 56-year-old woman presented to the ophthalmology clinic with acute onset of right eye pain 24 h after receiving her first Zolendronic acid infusion. Sh...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1063-8
更新日期:2019-02-14 00:00:00
abstract:BACKGROUND:Idiopathic orbital pseudotumour is rare in children. We report a case of bilateral paediatric idiopathic orbital pseudotumour and review the characteristics of this case. CASE PRESENTATION:A 14-year-old female patient presented at our Department of Pulmonary and Critical Care Medicine (PCCM) with complaints...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01718-0
更新日期:2020-11-16 00:00:00
abstract:BACKGROUND:Investigating the efficacy and safety of phacoemulsification with intraocular lens (IOL) implantation in corneal opacities. METHODS:This retrospective study was conducted in a tertiary medical center. Twenty-three eyes of 19 patients with cataracts and corneal opacities obscuring the pupillary center having...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0765-7
更新日期:2018-04-23 00:00:00
abstract:BACKGROUND:Previous techniques resulted with low rates of successful fusion after the surgeries and high necessity of additional surgeries in the treatment of thyroid orbitopathy related strabismus. In this study, reviewing the results of our patients who had surgical correction with relaxed muscle positioning techniqu...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0974-0
更新日期:2018-11-23 00:00:00
abstract:BACKGROUND:Perfluorocarbon liquid (PFCL) is widely used as an intraoperative heavy tamponade to flatten the retina and is replaced with silicone oil (SO) at the end of the surgery. Due to the long tamponade period, the SO is known to remain attached to the retina at the time of removal, and is commonly termed "sticky o...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0745-y
更新日期:2018-03-27 00:00:00
abstract:PURPOSE:Outcome measurements currently used in chronic uveitis care fail to cover the full patient perspective. The aim of this study is to develop a conceptual model of the factors that adult patients with chronic uveitis consider to be important when evaluating the impact of their disease and treatment. METHODS:A qu...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01388-y
更新日期:2020-03-30 00:00:00
abstract:BACKGROUND:Acute acquired comitant esotropia (AACE) is a type of strabismus characterized by a sudden onset of large angle esotropia with diplopia, which often occurs in children after infancy, teenagers, and young adolescents. However, studies on the surgical outcomes of only adults are rare. The purpose of this artic...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01793-3
更新日期:2021-01-18 00:00:00
abstract:BACKGROUND:To investigate machine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-box" approaches, for automated diagnosis of Age-related Macular Degeneration (AMD). METHODS:Data from healthy subjects and patients diagnosed with AMD or other retinal diseases were collecte...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-15-10
更新日期:2015-01-27 00:00:00
abstract:BACKGROUND:Iridoschisis is a rare condition that is characterized by the separation of the iris stroma into layers, with portions of the anterior layer floating freely in the aqueous humour. Here, we report three cases of iridoschisis that were complicated by either a cataract or glaucoma. Based on these cases, we spec...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-017-0418-2
更新日期:2017-03-14 00:00:00
abstract:BACKGROUND:The effectiveness of ranibizumab in the treatment of diabetic macular edema has been proven with large clinical trials. For bevacizumab only two clinical trials have been published and a head-to-head comparison is lacking to date. However, if proved non-inferior to ranibizumab, use of the off-label bevacizum...
journal_title:BMC ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12886-015-0043-x
更新日期:2015-07-07 00:00:00
abstract:BACKGROUND:To evaluate the changes of choroidal vascular structures in patients after phacoemulsification surgery. METHODS:A self-control study was conducted on 36 eyes of 36 patients who had uneventful phacoemulsification. Choroidal images were acquired preoperatively, 7 days (D7), 1 month (M1), and 3 months (M3) aft...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0749-7
更新日期:2018-03-23 00:00:00
abstract:BACKGROUND:To analyze the positions of intraocular posterior Implantable Collamer Lens (ICL) and its possible relationship with vault. METHODS:This cross-sectional study included 72 patients with high myopia (134 eyes) who were followed up after phakic intraocular lens implantation. The postoperative time ranged from ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0783-5
更新日期:2018-05-09 00:00:00
abstract:BACKGROUND:To present a case report of a patient with a mixed choroidal neovascular membrane (CNV) with an asymmetric response to ranibizumab diagnosed on optical coherence tomography angiography (OCTa). CASE PRESENTATION:A 61-year-old male was referred to our department in September 2017 due to decreased vision in hi...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-021-01810-z
更新日期:2021-01-15 00:00:00
abstract::Mucins locate to the apical surfaces of all wet-surfaced epithelia including ocular surface. The functions of the mucins include anti-adhesive, lubrication, water retention, allergens and pathogen barrier function. Ocular surface pathologies, i.e. dry eye syndrome or allergic conjunctivitis, are reportedly associated ...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-015-0137-5
更新日期:2015-12-17 00:00:00
abstract:BACKGROUND:Older drivers have a crash rate nearly equal to that of young drivers whose crash rate is the highest among all age groups. Contrast sensitivity impairment is common in older adults. The purpose of this study is to examine whether parameters from the photopic and mesopic contrast sensitivity functions (CSF) ...
journal_title:BMC ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12886-020-1331-7
更新日期:2020-02-04 00:00:00
abstract:BACKGROUND:Previous analyses of real-life data indicated that injection frequency and health care costs did not differ for anti-VEGF treatment with aflibercept and ranibizumab. The objective of this study was to investigate whether this finding persisted when analysing a longer time period after licensing. METHODS:Ret...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0617-x
更新日期:2017-12-04 00:00:00
abstract:BACKGROUND:The primary aim was to estimate the incidence of primary and secondary childhood glaucoma in Scotland over a 2-year period. The secondary aim was to gauge the confidence and experience of ophthalmologists in Scotland in managing these patients. METHODS:A 7 question electronic survey was distributed to all c...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01347-7
更新日期:2020-02-27 00:00:00
abstract:BACKGROUND:Adolescent KC is a special segment of the general KC population because an adolescents's eyes are still susceptible to blurred vision and optical defocus during the sensitive period of ocular and visual development. In the present study, we evaluated the ocular dimensions of 53 KC adolescents. METHODS:One h...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0713-6
更新日期:2018-02-13 00:00:00
abstract::An amendment to this paper has been published and can be accessed via the original article. ...
journal_title:BMC ophthalmology
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12886-020-01572-0
更新日期:2020-07-31 00:00:00
abstract:BACKGROUND:To evaluate the relationships between Reichert Ocular Response Analyzer (ORA) parameters corneal hysteresis (CH) and corneal response factor (CRF) and ocular dimensions, age and intraocular pressure. METHODS:Two hundred and twelve eyes of 212 participants with no ocular pathology had CH and CRF measured wit...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-11
更新日期:2014-01-30 00:00:00
abstract:BACKGROUND:The repertoire of free-living protozoa in contact lens solutions is poorly known despite the fact that such protozoa may act as direct pathogens and may harbor intra-cellular pathogens. METHODS:Between 2009 and 2014, the contact lens solutions collected from patients presenting at our Ophthalmology Departme...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0370-6
更新日期:2016-10-29 00:00:00
abstract:BACKGROUND:To determine the most effective route of administration of corticosteroids in the treatment of ocular surface disease, by characterizing the difference between oral prednisolone and topical dexamethasone administration using an animal model. METHODS:Pharmacokinetic analyses determined the corticosteroid con...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0339-5
更新日期:2016-09-05 00:00:00