Abstract:
BACKGROUND:Adolescent KC is a special segment of the general KC population because an adolescents's eyes are still susceptible to blurred vision and optical defocus during the sensitive period of ocular and visual development. In the present study, we evaluated the ocular dimensions of 53 KC adolescents. METHODS:One hundred and six KC eyes of 53 (42 boys and 11 girls) KC adolescents (age 15.5 ± 1.7 years, range 11 to 18) were involved in this retrospective study. The eye with more severe KC (Severe Group) of each patient was compared with their less affected eye (Mild Group). Optical axial length (OAL) was measured by optical coherence biometry (IOL-master). Central corneal thickness, anterior chamber depth (ACD), flat keratometry value, steep keratometry value, and maximum keratometry value were assessed with an anterior segment analyzer (Pentacam HR). Anterior segment length (ASL) was manually measured from the 25 scheimpflug images captured by the Pentacam HR with the mean value recorded. The posterior segment length (PSL) was calculated with the formula "PSL = OAL-ASL". RESULTS:The mean ACD, OAL, ASL, and PSL values of the Severe Group were 3.51 ± 0.32 mm, 24.76 ± 1.24 mm, 4.01 ± 0.30 mm and 20.76 ± 1.15 mm.While those of the Mild Group were 3.36 ± 0.29 mm, 24.97 ± 1.40 mm, 3.94 ± 0.35 mm and 21.03 ± 1.31 mm. The Severe Group has significantly higher ACD (t = 4.539, P < 0.001) value but lower OAL (t = - 3.120, P = 0.003) and PSL (t = - 4.537, P < 0.001) values when compared with those of the Mild Group. For the Severe Group, the Kmax values were significantly correlated with the SE values (R = - 0.385, P = 0.004), the ACD values (R = 0.375, P = 0.006), the ASL values (R = 0.308, P = 0.025) and the PSL values (R = - 0.317, P = 0.021), but not with the OAL values (R = - 0.220, P = 0.114). In the Mild Group, the Kmax values were negatively correlated with the SE (R = - 0.577, P < 0.001), OAL(R = - 0.533, P < 0.001), and PSL (R = - 0.523, P < 0.001) values, but not with ACD (R = - 0.110, P = 0.434) or ASL (R = - 0.182, P = 0.192) values. CONCLUSIONS:For adolescent KC, the more keratoconic eyes may be characterized by deeper ACD but shorter OAL and PSL, when compared with the less affected ones.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Jian W,Shen Y,Chen Y,Tian M,Zhou Xdoi
10.1186/s12886-018-0713-6subject
Has Abstractpub_date
2018-02-13 00:00:00pages
43issue
1issn
1471-2415pii
10.1186/s12886-018-0713-6journal_volume
18pub_type
杂志文章abstract:BACKGROUND:Highly aggressive Burkitt lymphoma (BL) with rapidly progressive painful proptosis of the right eye is rarely encountered. CASE PRESENTATION:A 31-year-old Caucasian female presented with rapidly progressive painful proptosis of the right eye and poor visual acuity. Diagnostic Computer tomography, magnetic r...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-109
更新日期:2014-09-08 00:00:00
abstract:BACKGROUND:To assess the precision and agreement of measurements of higher order aberrations (HOAs) obtained with a ray tracing aberrometer (iTrace) and a Hartmann-Shack aberrometer (Topcon KR-1 W). METHODS:Prospective evaluation of the diagnostic test. Data from the right eyes of 92 normal subjects obtained using the...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0683-8
更新日期:2018-01-27 00:00:00
abstract:BACKGROUND:With age, the human lens accumulates variety of substances that absorbs and fluorescence, which explains the color of yellow, brunescent and nigrescent cataract in terms of aging. The aim of this study was to assess lens fluorophores with properties comparable to those of advanced glycated end products (AGEs...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-6-10
更新日期:2006-03-06 00:00:00
abstract:BACKGROUND:A 23 year old white male with a history of social and behavioural problems attempted to blind himself chemically, with alcohol, and mechanically, with a razor blade. METHODS:Observational case report of a patient who self-inflicted bilateral scleral lacerations with a razor blade, after losing his job. RES...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-9-14
更新日期:2009-12-10 00:00:00
abstract:BACKGROUND:Glaucoma is a progressive disease responsible for the second commonest cause of blindness in the UK. Identifying appropriate patients for hospital care remains an ongoing challenge for all UK hospital glaucoma services. The purpose of our study is to evaluate accuracy and outcome of community optometry refer...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0161-5
更新日期:2015-12-07 00:00:00
abstract::Conjunctival and subconjunctival fibrogenesis and inflammation are sight compromising side effects that can occur subsequent to glaucoma filtration surgery. Despite initial declines in intraocular pressure resulting from increasing aqueous outflow, one of the activated responses includes marshalling of proinflammatory...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-015-0134-8
更新日期:2015-12-17 00:00:00
abstract:BACKGROUND:Optical coherence tomography angiography is a novel imaging technique that allows dyeless in vivo visualization of the retinal and choroidal vasculature. The purpose of this study was to describe optical coherence tomography (OCT) angiography findings in patients with retinal arterial macroaneurysms (RAMs). ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0293-2
更新日期:2016-07-22 00:00:00
abstract:BACKGROUND:A cyclodialysis cleft often leads to direct communication between the anterior chamber and the suprachoroidal space. It is a rare condition that is encountered with blunt trauma, and less commonly, after surgery. Hypotony is the major sequelae that may lead to hypotonous maculopathy, optic disc edema, cornea...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01375-3
更新日期:2020-03-23 00:00:00
abstract:BACKGROUND:Cataract surgery in diabetics is more technically challenging due to a number of factors including poor intraoperative pupil dilation and a higher risk of vision threatening complications. This study evaluates the safety and efficacy of an intracameral combination of 2 mydriatics and 1 anesthetic (ICMA, Mydr...
journal_title:BMC ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12886-020-01343-x
更新日期:2020-03-03 00:00:00
abstract:BACKGROUND:Pterygium is a condition characterized by epithelial overgrowth of the cornea, inflammatory cell infiltration and an abnormal extracellular matrix accumulation. Chronic UV exposure is considered as a pathogenic factor of this disease. Proteasome is an intracellular multi-subunit protease complex that degrade...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0987-8
更新日期:2018-12-18 00:00:00
abstract:BACKGROUND:Stress-induced activation of the sympathetic nervous system leads to a cascade of metabolic reactions. Emotional stress is a more specific form of stress in which the stressor is a psychological response to a situation subjectively perceived as traumatic. Stress hormones can have a wide range of effects on t...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-019-1075-4
更新日期:2019-03-08 00:00:00
abstract:BACKGROUND:Bone marrow transplantation retinopathy is a rare condition affecting the posterior pole. The purpose of this case report is to highlight the possible risk factors and clinical features. CASE PRESENTATION:A 19y old male with relapsed and refractory acute lymphoblastic leukaemia was admitted under haematolog...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0855-6
更新日期:2018-09-14 00:00:00
abstract:BACKGROUND:To report six cases of CD34+ fibroblastic mesenchymal tumours, which are uncommon neoplasms in the orbit. CASE PRESENTATION:Six patients presenting with proptosis and palpable mass who were later diagnosed with fibrous solitary tumours, fibrous histocytoma or haemangiopericytoma in the orbit were included. ...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-017-0455-x
更新日期:2017-04-27 00:00:00
abstract:BACKGROUND:This paper presents and tests a comprehensive computerised system of analysis of digital images of posterior capsule opacification (PCO). It updates and expands significantly on a previous presentation to include facilities for selecting user defined central areas and for registering and subsequent merging o...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-6-30
更新日期:2006-08-23 00:00:00
abstract:BACKGROUND:Iridoschisis is a rare condition that is characterized by the separation of the iris stroma into layers, with portions of the anterior layer floating freely in the aqueous humour. Here, we report three cases of iridoschisis that were complicated by either a cataract or glaucoma. Based on these cases, we spec...
journal_title:BMC ophthalmology
pub_type: 杂志文章,评审
doi:10.1186/s12886-017-0418-2
更新日期:2017-03-14 00:00:00
abstract:BACKGROUND:To study the value and safety of aqueous humor polymerase chain reaction (PCR) analysis for Herpes simplex, varicella zoster, cytomegalovirus, Epstein-Barr virus and Toxoplasma gondii in patients with uveitis. METHODS:Records of 45 consecutive patients with anterior and posterior uveitis who underwent AC pa...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0369-z
更新日期:2016-10-28 00:00:00
abstract:BACKGROUND:Blank cartridge guns are generally regarded as being harmless and relative safe. However recent published articles demonstrated that the gas pressure from the exploding propellant of blank cartridge is powerful enough to penetrate the thoracic wall, abdominal muscle, small intestine and the skull. And there ...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-23
更新日期:2014-03-03 00:00:00
abstract:BACKGROUND:Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological platforms to reveal transcriptome profiles and identify any differentially expressed genes...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01348-6
更新日期:2020-03-06 00:00:00
abstract:BACKGROUND:To assess the efficacy of the intravitreal (IVT) injection of Triamcinolone Acetonide (TA) as compared to posterior subtenon (SBT) capsule injection for the treatment of cystoid diabetic macular edema. METHODS:Fourteen patients with type II diabetes mellitus and on insulin treatment, presenting diffuse cyst...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-8-5
更新日期:2008-03-17 00:00:00
abstract:BACKGROUND:There is no generally accepted medical or surgical treatment to stop the progressive course of retinitis pigmentosa. Previous studies have suggested lutein as a potential treatment with positive effects on macular pigment density. The objective of this study was to examine the effect of lutein supplementatio...
journal_title:BMC ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2415-6-23
更新日期:2006-06-07 00:00:00
abstract:BACKGROUND:To present a case of conjunctival lymphoma in a young woman complicated by pregnancy. CASE PRESENTATION:A 38-year-old previously healthy woman presented with a 2-year history of progressive right blepharoptosis. Giant papillomatous sessile masses were identified in the upper and lower fornix bilaterally and...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0518-z
更新日期:2017-07-27 00:00:00
abstract:BACKGROUND:Although the association between metabolic syndrome and intraocular pressure is well known, the relationship between the intraocular pressure and different combination of the components of metabolic syndrome has not been actively researched yet. The study aimed to investigate the relationship between the int...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0263-8
更新日期:2016-06-06 00:00:00
abstract:BACKGROUND:To investigate the effect of idiopathic epiretinal membrane (ERM) on the retinal-image quality and psychophysical contrast sensitivity function (CSF). METHODS:Forty-four subjects with diagnosis of idiopathic unilateral ERM were enrolled in this cross-sectional observational clinical study. The fellow unaffe...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0957-1
更新日期:2018-11-07 00:00:00
abstract:BACKGROUND:Idiopathic elevated episcleral venous pressure (IEEVP) or idiopathic dilated episcleral veins (IDEV) is a rare abnormality, and thus therapeutic treatment for this condition rarely is discussed. We report a case of a patient with bilateral glaucoma secondary to IDEV for whom intraocular pressures (IOPs) were...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-018-0892-1
更新日期:2018-08-23 00:00:00
abstract:BACKGROUND:This is a case of spontaneous toric implantable collamer lens (TICL) rotation that occurred twice in the left eye of a patient. CASE PRESENTATION:A 24-year-old gentleman received TICL implantation for treatment of myopic astigmatism encountered with spontaneous rotation of approximately 90° from its origina...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-020-01597-5
更新日期:2020-08-28 00:00:00
abstract:BACKGROUND:Despite the progress in vitreoretinal surgery and the importance of silicone oil as an adjunct for the treatment of complex forms of retinal detachment, controversy still surrounds the issue of selecting the proper oil viscosity for clinical use. Herein, we evaluate the outcomes of retinal detachment (RD) su...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-6-21
更新日期:2006-05-31 00:00:00
abstract:BACKGROUND:Silicone oil tamponade is more frequently reserved for cases of complex retinal detachment. We describe the effects of different variations in oil ratios with the relatively unknown technique of double oil tamponade. METHODS:Retrospective case note review of nine patients with complex rhegmatogenous retinal...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-017-0660-7
更新日期:2017-12-28 00:00:00
abstract:BACKGROUND:We explore and compare the advantages and disadvantages of different operating methods for a peripheral iridectomy (PI) for phakic posterior chamber implantable contact lens (ICL) implantation in patients with dark-brown irides. METHODS:Forty-six patients completed this prospective comparative study. Neodym...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-016-0229-x
更新日期:2016-05-05 00:00:00
abstract:BACKGROUND:Retinal artery occlusion caused by myxoma is relatively rare. There are several points that should be taken into consideration to avoid overlooking this disorder. CASE PRESENTATION:This case report describes a 43-year-old woman with sudden vision loss in her left eye for 20 days after single sudden syncope....
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/1471-2415-14-164
更新日期:2014-12-23 00:00:00
abstract:BACKGROUND:Central Serous Chorioretinopathy (CSC) has been previously reported as an infrequent complication of pregnancy that usually resolves spontaneously after delivery, with minimal or no sequel. We report a case of a severe form of CSC in an uncomplicated pregnancy with extensive subfoveal exudates and severe per...
journal_title:BMC ophthalmology
pub_type: 杂志文章
doi:10.1186/s12886-015-0169-x
更新日期:2015-12-22 00:00:00